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Volumn 52, Issue 1, 1999, Pages 19-24

Liver enriched transcription factors and differentiation of hepatocellular carcinoma

Author keywords

CCAAT enhancer binding protein; D binding protein; Hepatic nuclear factors; Liver enriched transcription factor

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA FETOPROTEIN; BINDING PROTEIN; DNA; MESSENGER RNA; NUCLEAR FACTOR I; NUCLEAR FACTOR III; NUCLEAR FACTOR IV; NUCLEAR FACTOR VI; NUCLEAR PROTEIN; PREALBUMIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0032949466     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.52.1.19     Document Type: Article
Times cited : (91)

References (86)
  • 1
    • 0023645070 scopus 로고
    • Regulation of inducible and tissue-specific gene expression
    • 1 Maniatis S, Goodbourn S, Fischer J. Regulation of inducible and tissue-specific gene expression. Science 1987; 245:1237-45.
    • (1987) Science , vol.245 , pp. 1237-1245
    • Maniatis, S.1    Goodbourn, S.2    Fischer, J.3
  • 2
    • 0002990053 scopus 로고
    • Genetic control of hepatocyte differentiation
    • Arias IM, Boyer JL, Fausto N, et al, eds. New York: Raven Press
    • 2 Zaret KS. Genetic control of hepatocyte differentiation. In: Arias IM, Boyer JL, Fausto N, et al, eds. The liver: biology and pathology, 3rd ed. New York: Raven Press, 1994:53-68.
    • (1994) The Liver: Biology and Pathology, 3rd Ed. , pp. 53-68
    • Zaret, K.S.1
  • 3
    • 0029962261 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and hepatocyte differentaion
    • 3 Cereghini S. Liver-enriched transcription factors and hepatocyte differentaion. FASEB J 1996;10:267-82.
    • (1996) FASEB J , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 4
    • 85038198834 scopus 로고    scopus 로고
    • Withdrawn
    • 4 Withdrawn.
  • 5
    • 0029002703 scopus 로고
    • The potential for the use of cell proliferation and oncogene expression as intermediate markers during liver carcinogenesis
    • 5 Mehta R. The potential for the use of cell proliferation and oncogene expression as intermediate markers during liver carcinogenesis. Cancer Lett 1995;93:85-102.
    • (1995) Cancer Lett , vol.93 , pp. 85-102
    • Mehta, R.1
  • 6
    • 0023663915 scopus 로고
    • The interplay of DNA binding proteins on the promoter of mouse albumin gene
    • 6 Lichtsteiner S, Wuarin J, Schibler U. The interplay of DNA binding proteins on the promoter of mouse albumin gene. Cell 1987;5:963-73.
    • (1987) Cell , vol.5 , pp. 963-973
    • Lichtsteiner, S.1    Wuarin, J.2    Schibler, U.3
  • 7
    • 0001684630 scopus 로고
    • Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters
    • 7 Cereghini S, Blumenfeld M, Yaniv M. Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters. Proc Natl Acad Sci USA 1988;85:7937-41.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7937-7941
    • Cereghini, S.1    Blumenfeld, M.2    Yaniv, M.3
  • 8
    • 0024023932 scopus 로고
    • Two distinct factors interact with the promoter regions of several liver-specific genes
    • 8 Hardon E, Paonessa G, Frain M, et al. Two distinct factors interact with the promoter regions of several liver-specific genes. EMBO J 1988;7:1711-19.
    • (1988) EMBO J , vol.7 , pp. 1711-1719
    • Hardon, E.1    Paonessa, G.2    Frain, M.3
  • 9
    • 0023628342 scopus 로고
    • Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-antitrypsin promoters
    • 9 Courtois G, Morgan JG, Campbell LA, et al. Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-antitrypsin promoters. Science 1987;238:688-92.
    • (1987) Science , vol.238 , pp. 688-692
    • Courtois, G.1    Morgan, J.G.2    Campbell, L.A.3
  • 10
    • 0023672976 scopus 로고
    • The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites
    • 10 Costa RH, Lai E, Grayson DR, et al. The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites. Mol Cell Biol 1988;8:81-90.
    • (1988) Mol Cell Biol , vol.8 , pp. 81-90
    • Costa, R.H.1    Lai, E.2    Grayson, D.R.3
  • 11
    • 0026334740 scopus 로고
    • Gene structure and expression of the rat cytochrome P450IIC13, polymorphic male-specific cytochrome in the P450IIC subfamily
    • 11 Eguchi H, Westin S, Ström A. Gene structure and expression of the rat cytochrome P450IIC13, polymorphic male-specific cytochrome in the P450IIC subfamily. Biochemistry 1991;30:10844-9.
    • (1991) Biochemistry , vol.30 , pp. 10844-10849
    • Eguchi, H.1    Westin, S.2    Ström, A.3
  • 12
    • 0025811870 scopus 로고
    • The different tissue transcription patterns of genes for HNF-1, C EBP, HNF3, and HNF-4, protein factors that govern liver specific transcription
    • 12 Xanthopoulos K, Prezioso V, Chen W, et al. The different tissue transcription patterns of genes for HNF-1, C EBP, HNF3, and HNF-4, protein factors that govern liver specific transcription. Proc Natl Acad Sci USA 1991;88: 3807-11.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3807-3811
    • Xanthopoulos, K.1    Prezioso, V.2    Chen, W.3
  • 13
    • 0024452687 scopus 로고
    • The liver-specific transcription factor LFB1 contains a highly diverged homeobox DNA binding domain
    • 13 Frain M, Swart G, Monaci P. The liver-specific transcription factor LFB1 contains a highly diverged homeobox DNA binding domain. Cell 1989;59:145-57.
    • (1989) Cell , vol.59 , pp. 145-157
    • Frain, M.1    Swart, G.2    Monaci, P.3
  • 14
    • 0025853775 scopus 로고
    • LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia
    • 14 DeSimone V, DeMagistris L, Lazzaro D, et al. LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia. EMBO J 1991;10:1435-43.
    • (1991) EMBO J , vol.10 , pp. 1435-1443
    • DeSimone, V.1    DeMagistris, L.2    Lazzaro, D.3
  • 15
    • 0025775278 scopus 로고
    • vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
    • 15 Rey-Campos J, Chouard T, Yaniv M, et al. vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J 1991;10:1445-57.
    • (1991) EMBO J , vol.10 , pp. 1445-1457
    • Rey-Campos, J.1    Chouard, T.2    Yaniv, M.3
  • 16
    • 0025892211 scopus 로고
    • HNF-1α and HNF-1β (vHNF-1) share dimerization and homeodomains, but not activation domains, and form heterodimers in vitro
    • 16 Mendel DB, Hansen LP, Graves MK, et al. HNF-1α and HNF-1β (vHNF-1) share dimerization and homeodomains, but not activation domains, and form heterodimers in vitro. Genes Dev 1991;5:1042-56.
    • (1991) Genes Dev , vol.5 , pp. 1042-1056
    • Mendel, D.B.1    Hansen, L.P.2    Graves, M.K.3
  • 17
    • 0026440658 scopus 로고
    • Expression pattern of vHNF-1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles
    • 17 Cereghini S, Ott MO, Power S, et al. Expression pattern of vHNF-1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles. Development 1992;116:783-97.
    • (1992) Development , vol.116 , pp. 783-797
    • Cereghini, S.1    Ott, M.O.2    Power, S.3
  • 18
    • 0024313881 scopus 로고
    • Developmental appearance of transcription factors that regulate liver-specific expression of the aldolase B gene
    • 18 Tsutsumi K, Ito K, Ishikawa K. Developmental appearance of transcription factors that regulate liver-specific expression of the aldolase B gene. Mol Cell Biol 1989;9:4923-31.
    • (1989) Mol Cell Biol , vol.9 , pp. 4923-4931
    • Tsutsumi, K.1    Ito, K.2    Ishikawa, K.3
  • 19
    • 0024330479 scopus 로고
    • A liver-specific nuclear factor interacts with a region of the large surface protein gene in human hepatitits B virus
    • 19 Chang HK, Wang BY, Yuh CH, et al. A liver-specific nuclear factor interacts with a region of the large surface protein gene in human hepatitits B virus. Mol Cell Biol 1989;9: 5189-97.
    • (1989) Mol Cell Biol , vol.9 , pp. 5189-5197
    • Chang, H.K.1    Wang, B.Y.2    Yuh, C.H.3
  • 20
    • 0024061257 scopus 로고
    • A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells
    • 20 Cereghini S, Blumenfeld M, Yaniv M. A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells. Genes Dev 1988;2:957-74.
    • (1988) Genes Dev , vol.2 , pp. 957-974
    • Cereghini, S.1    Blumenfeld, M.2    Yaniv, M.3
  • 21
    • 0025290218 scopus 로고
    • Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF-1/LFB1
    • 21 Cereghini S, Yaniv M, Cortese R. Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF-1/LFB1. EMBO J 1990;9:2257-63.
    • (1990) EMBO J , vol.9 , pp. 2257-2263
    • Cereghini, S.1    Yaniv, M.2    Cortese, R.3
  • 22
    • 0030273537 scopus 로고    scopus 로고
    • Expression ratio of hepatocyte nuclear factor-1 to variant hepatocyte nuclear factor-1 in differentiation of hepatocellular carcinoma and hepatoblastoma
    • 22 Ninomiya T, Hayashi Y, Saijoh K, et al. Expression ratio of hepatocyte nuclear factor-1 to variant hepatocyte nuclear factor-1 in differentiation of hepatocellular carcinoma and hepatoblastoma. J Hepatol 1996;25:445-53.
    • (1996) J Hepatol , vol.25 , pp. 445-453
    • Ninomiya, T.1    Hayashi, Y.2    Saijoh, K.3
  • 23
    • 0029915773 scopus 로고    scopus 로고
    • Expression of hepatocyte-enriched nuclear transcription factors in mouse liver tumors
    • 23 Kalkuhl A, Kaestner K. Buchmann A, et al. Expression of hepatocyte-enriched nuclear transcription factors in mouse liver tumors. Carcinogenesis 1996;17:609-12.
    • (1996) Carcinogenesis , vol.17 , pp. 609-612
    • Kalkuhl, A.1    Kaestner, K.2    Buchmann, A.3
  • 24
    • 0013506103 scopus 로고    scopus 로고
    • Expression of liver-enriched transcription factors C/EBPα C/EBPβ, HNF-1 and HNF-4 in preneoplastic nodules hepatocellular carcinoma in rat liver
    • 24 Flodby P, Liao D.Z, Blanck A, et al. Expression of liver-enriched transcription factors C/EBPα C/EBPβ, HNF-1 and HNF-4 in preneoplastic nodules hepatocellular carcinoma in rat liver. Mol Carcinog 1996;17: 600-12.
    • (1996) Mol Carcinog , vol.17 , pp. 600-612
    • Flodby, P.1    Liao, D.Z.2    Blanck, A.3
  • 25
    • 0031595805 scopus 로고    scopus 로고
    • Expression of HNF-1α and HNF-1β in various histological differentiations of hepatocellular carcinoma
    • 25 Wang W, Hayashi Y, Ninomiya T, et al. Expression of HNF-1α and HNF-1β in various histological differentiations of hepatocellular carcinoma. J Pathol 1998;184:272-8.
    • (1998) J Pathol , vol.184 , pp. 272-278
    • Wang, W.1    Hayashi, Y.2    Ninomiya, T.3
  • 26
    • 0028198313 scopus 로고
    • Lowered amounts of the tissue-specific tanscription factor LFB1 (HNF-1) correlate with decreased levels of glutathione S-transferase a messenger RNA in human renal cell carcinoma
    • 26 Clairmont A, Ebert T, Weber H, et al. Lowered amounts of the tissue-specific tanscription factor LFB1 (HNF-1) correlate with decreased levels of glutathione S-transferase a messenger RNA in human renal cell carcinoma. Cancer Res 1994;54:1319-23.
    • (1994) Cancer Res , vol.54 , pp. 1319-1323
    • Clairmont, A.1    Ebert, T.2    Weber, H.3
  • 27
    • 0013512684 scopus 로고
    • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
    • 27 Sladek F, Zhong W, Lai E, et al. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990;10:1239-43.
    • (1990) Genes Dev , vol.10 , pp. 1239-1243
    • Sladek, F.1    Zhong, W.2    Lai, E.3
  • 28
    • 0024556115 scopus 로고
    • Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antirypsin gene
    • 28 Costa R, Grayson D, Darnell J, Jr. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antirypsin gene. Mol Cell Biol 1989;9: 1415-25.
    • (1989) Mol Cell Biol , vol.9 , pp. 1415-1425
    • Costa, R.1    Grayson, D.2    Darnell J., Jr.3
  • 29
    • 0026589377 scopus 로고
    • Antagonism between apolipoprotein A1 regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein in liver and intestinal cells
    • 29 Mietus-Snyder M, Sladek F, Ginsburg S, et al. Antagonism between apolipoprotein A1 regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein in liver and intestinal cells. Mol Cell Biol 1992;12:1708-18.
    • (1992) Mol Cell Biol , vol.12 , pp. 1708-1718
    • Mietus-Snyder, M.1    Sladek, F.2    Ginsburg, S.3
  • 30
    • 0345245156 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentated hepatoma cells
    • 30 Späth G, Weiss M. Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentated hepatoma cells. Mol Cell Biol 1997;17:1913-22.
    • (1997) Mol Cell Biol , vol.17 , pp. 1913-1922
    • Späth, G.1    Weiss, M.2
  • 31
    • 0032559647 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
    • 31 Späth G, Weiss M. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J Cell Biol 1998;140:935-46.
    • (1998) J Cell Biol , vol.140 , pp. 935-946
    • Späth, G.1    Weiss, M.2
  • 32
    • 0028108926 scopus 로고
    • Embryonic fat-cell lineage in Drosophila melanogaster
    • 32 Hoshizaki KD, Blackburn T, Price C, et al. Embryonic fat-cell lineage in Drosophila melanogaster. Development 1994;120:2489-99.
    • (1994) Development , vol.120 , pp. 2489-2499
    • Hoshizaki, K.D.1    Blackburn, T.2    Price, C.3
  • 33
    • 0028799497 scopus 로고
    • The DNA binding activity of the liver transcription factors LFB1 (HNF1) and HNF4 varies coordinately in rat hepatocellular carcinoma
    • 33 Stumpf H, Senkel S, Rabes H, et al. The DNA binding activity of the liver transcription factors LFB1 (HNF1) and HNF4 varies coordinately in rat hepatocellular carcinoma. Carcinogenesis 1995;16:143-5.
    • (1995) Carcinogenesis , vol.16 , pp. 143-145
    • Stumpf, H.1    Senkel, S.2    Rabes, H.3
  • 34
    • 0030848766 scopus 로고    scopus 로고
    • Modulation of hepatic gene expression by hepatocyte nuclear factor 1
    • 34 Ktistaki E, Talianidis I. Modulation of hepatic gene expression by hepatocyte nuclear factor 1. Science 1997;277:109-12.
    • (1997) Science , vol.277 , pp. 109-112
    • Ktistaki, E.1    Talianidis, I.2
  • 35
    • 0028820158 scopus 로고
    • Recruitment of hepatocytre nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential
    • 35 Ktistaki E, Ktistakis N, Papadogeorgaki E, et al. Recruitment of hepatocytre nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential. Proc Natl Acad Sci USA 1995;92:9876-80.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9876-9880
    • Ktistaki, E.1    Ktistakis, N.2    Papadogeorgaki, E.3
  • 36
    • 0030877342 scopus 로고    scopus 로고
    • Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4
    • 36 Viollet B, Kahn A, Raymondjean. Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4. Mol Cell Biol 1997; 17:4208-19.
    • (1997) Mol Cell Biol , vol.17 , pp. 4208-4219
    • Viollet, B.1    Kahn, A.2    Raymondjean3
  • 37
    • 0027432554 scopus 로고
    • Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference
    • 37 Johnson P. Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference. Mol Cell Biol 1993;13:6919-30.
    • (1993) Mol Cell Biol , vol.13 , pp. 6919-6930
    • Johnson, P.1
  • 38
    • 0024295767 scopus 로고
    • The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite
    • 38 Landschulz W, Johnson P, McKnight S. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. Science 1988;240:1759-64.
    • (1988) Science , vol.240 , pp. 1759-1764
    • Landschulz, W.1    Johnson, P.2    McKnight, S.3
  • 39
    • 0027049805 scopus 로고
    • The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted a helices: Crystal structure of the protein DNA complex
    • 39 Ellenberger T, Brandle C, Struhl K, et al. The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted a helices: crystal structure of the protein DNA complex. Cell 1993;71:1223-37.
    • (1993) Cell , vol.71 , pp. 1223-1237
    • Ellenberger, T.1    Brandle, C.2    Struhl, K.3
  • 40
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • 40 Cao Z, Umek R, McKnight S. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 1991;5:1538-52.
    • (1991) Genes Dev , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.2    McKnight, S.3
  • 41
    • 0024711273 scopus 로고
    • Tissue-specific expression, developmental regulation, genetic mapping of the gene encoding CCAAT/enhancer binding protein
    • 41 Birkenmeier E, Gwynn B, Howard S, et al. Tissue-specific expression, developmental regulation, genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev 1989;3:1146-56.
    • (1989) Genes Dev , vol.3 , pp. 1146-1156
    • Birkenmeier, E.1    Gwynn, B.2    Howard, S.3
  • 42
    • 0023322681 scopus 로고
    • Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses
    • 42 Johnson P, Landschulz W, Graves B, et al. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev 1987;1:133-46.
    • (1987) Genes Dev , vol.1 , pp. 133-146
    • Johnson, P.1    Landschulz, W.2    Graves, B.3
  • 43
    • 0024046156 scopus 로고
    • Isolation of a recombinant copy of the gene encoding C/EBP
    • 43 Landschulz W, Johnson P, Adashi E, et al. Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev 1988;2:786-800.
    • (1988) Genes Dev , vol.2 , pp. 786-800
    • Landschulz, W.1    Johnson, P.2    Adashi, E.3
  • 44
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: A component of differentiation switch
    • 44 Umek R, Friedman A, McKnight S. CCAAT-enhancer binding protein: a component of differentiation switch. Science 1991;251:288-92.
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.1    Friedman, A.2    McKnight, S.3
  • 45
    • 0028564903 scopus 로고
    • CCAAT-enhancer binding protein a is sufficient to initiate the 3T3-L1 adipocyte differentiation program
    • 45 Lin F, Lane M. CCAAT-enhancer binding protein a is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci USA 1994;91:8757-61.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8757-8761
    • Lin, F.1    Lane, M.2
  • 46
    • 0028129499 scopus 로고
    • Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells
    • 46 Freytag SO, Paielli DL, Gilbert JD. Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev 1994;8:1654-63.
    • (1994) Genes Dev , vol.8 , pp. 1654-1663
    • Freytag, S.O.1    Paielli, D.L.2    Gilbert, J.D.3
  • 47
    • 0026048640 scopus 로고
    • The CCAAT/enhancer binding protein and its role in adipocyte differentiation: Evidence for direct involvement in terminal adipocyte development
    • 47 Samuelsson L, Stromberg K, Vikman K, et al. The CCAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte development. EMBO J 1991;10:3787-93.
    • (1991) EMBO J , vol.10 , pp. 3787-3793
    • Samuelsson, L.1    Stromberg, K.2    Vikman, K.3
  • 48
    • 0026511284 scopus 로고
    • Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
    • 48 Lin FT, Lane MD. Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev 1992;6:533-44.
    • (1992) Genes Dev , vol.6 , pp. 533-544
    • Lin, F.T.1    Lane, M.D.2
  • 49
    • 0024725630 scopus 로고
    • CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cell
    • 49 Friedman AD, Landschulz WH, McKnight SL. CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cell. Genes Dev 1989;3:1314-22.
    • (1989) Genes Dev , vol.3 , pp. 1314-1322
    • Friedman, A.D.1    Landschulz, W.H.2    McKnight, S.L.3
  • 50
    • 0013535442 scopus 로고
    • Positive and negative regulatory elements in mouse albumin enhancer
    • 50 Herbst RS, Friedman N, Darnell JE, et al. Positive and negative regulatory elements in mouse albumin enhancer. Proc Natl Acad Sci USA 1989;86:1533-57.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1533-1557
    • Herbst, R.S.1    Friedman, N.2    Darnell, J.E.3
  • 51
    • 0024556115 scopus 로고
    • Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha1-antitrypsin genes
    • 51 Costa RH, Grayson DR, Darnell JE. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha1-antitrypsin genes. Mol Cell Biol 1989;9:1415-25.
    • (1989) Mol Cell Biol , vol.9 , pp. 1415-1425
    • Costa, R.H.1    Grayson, D.R.2    Darnell, J.E.3
  • 52
    • 0026638061 scopus 로고
    • Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBPα) gene expression during hepatocyte proliferation in the regenerating liver and in culture
    • 52 Mischoulon D, Rana B, Nancy L, et al. Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBPα) gene expression during hepatocyte proliferation in the regenerating liver and in culture. Mol Cell Biol 1992;12: 2553-60.
    • (1992) Mol Cell Biol , vol.12 , pp. 2553-2560
    • Mischoulon, D.1    Rana, B.2    Nancy, L.3
  • 53
    • 0029976068 scopus 로고    scopus 로고
    • ACCAAT/enhancer-binding protein (C/EBPα) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein
    • 53 Timchenko NA, Wilde M, Nakanishi M, et al. ACCAAT/enhancer-binding protein (C/EBPα) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Genes Dev 1996;10:804-15.
    • (1996) Genes Dev , vol.10 , pp. 804-815
    • Timchenko, N.A.1    Wilde, M.2    Nakanishi, M.3
  • 54
    • 85038206397 scopus 로고    scopus 로고
    • Withdrawn
    • 54 Withdrawn.
  • 55
    • 0030022255 scopus 로고    scopus 로고
    • Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein
    • 55 Watkins, PJ, Condreay JP, Huber BE, et al. Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein. Cancer Res 1996;56:1063-7.
    • (1996) Cancer Res , vol.56 , pp. 1063-1067
    • Watkins, P.J.1    Condreay, J.P.2    Huber, B.E.3
  • 56
    • 85038196879 scopus 로고    scopus 로고
    • Withdrawn
    • 56 Withdrawn.
  • 57
    • 0025297353 scopus 로고
    • A nuclear facter for IL-6 expression (NF-IL6) is a member of the C/EBP family
    • 57 Akira S, Isshiki H, Sugita T, et al. A nuclear facter for IL-6 expression (NF-IL6) is a member of the C/EBP family. EMBO J 1990;9:1897-906.
    • (1990) EMBO J , vol.9 , pp. 1897-1906
    • Akira, S.1    Isshiki, H.2    Sugita, T.3
  • 58
    • 0028853334 scopus 로고
    • Targeted disruption of the NF-IL6 gene discloses its essential role in bacterial killing and tumor cytotoxicity by macrophages
    • 58 Tanaka T, Akira S, Yoshida K, et al. Targeted disruption of the NF-IL6 gene discloses its essential role in bacterial killing and tumor cytotoxicity by macrophages. Cell 1995;80:353-61.
    • (1995) Cell , vol.80 , pp. 353-361
    • Tanaka, T.1    Akira, S.2    Yoshida, K.3
  • 59
    • 0029024113 scopus 로고
    • Lymphoproliferative disorder and imbalanced T-helper response in C/EBPb-deficient mice
    • 59 Screpanti I, Romani L, Musiani P, et al. Lymphoproliferative disorder and imbalanced T-helper response in C/EBPb-deficient mice. EMBO J 1995;14:1932-41.
    • (1995) EMBO J , vol.14 , pp. 1932-1941
    • Screpanti, I.1    Romani, L.2    Musiani, P.3
  • 60
    • 0026501412 scopus 로고
    • Macrophage differentiation specific expression of NF-IL6, a transcription factor for IL-6
    • 60 Natsuka S, Akira S, Nishio Y, et al. Macrophage differentiation specific expression of NF-IL6, a transcription factor for IL-6. Blood 1992;79:460-6.
    • (1992) Blood , vol.79 , pp. 460-466
    • Natsuka, S.1    Akira, S.2    Nishio, Y.3
  • 61
    • 0031029557 scopus 로고    scopus 로고
    • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein a-deficient mice
    • 61 Zhang DE, Zhang P Wang ND, et al. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein a-deficient mice. Proc Natl Acad Sci USA 1997;94:569-74.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 569-574
    • Zhang, D.E.1    Zhang, P.2    Wang, N.D.3
  • 62
    • 0025319528 scopus 로고
    • DBP, a liver-enriched transcriptional activator is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
    • 62 Mueller C R, Maire P, Schibler U. DBP, a liver-enriched transcriptional activator is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally. Cell 1990;61:279-91.
    • (1990) Cell , vol.61 , pp. 279-291
    • Mueller, C.R.1    Maire, P.2    Schibler, U.3
  • 63
    • 0027428137 scopus 로고
    • Circadian transcription of the cholesterol-7α hydroxylase gene may involve the liver enriched b-ZIP-protein DBP
    • 63 Lavery DJ, Schiblez V, Circadian transcription of the cholesterol-7α hydroxylase gene may involve the liver enriched b-ZIP-protein DBP. Genes Dev 1993;7:1871-84.
    • (1993) Genes Dev , vol.7 , pp. 1871-1884
    • Lavery, D.J.1    Schiblez, V.2
  • 64
    • 0027176792 scopus 로고
    • Dimerization specificity of the leucine zipper-containing bZip motif on DNA-binding: Prediction and rational design
    • 64 Vinson CR, Hai T, Boyd S. Dimerization specificity of the leucine zipper-containing bZip motif on DNA-binding: prediction and rational design. Genes Dev 1993;7:2081-6.
    • (1993) Genes Dev , vol.7 , pp. 2081-2086
    • Vinson, C.R.1    Hai, T.2    Boyd, S.3
  • 65
    • 0030445282 scopus 로고    scopus 로고
    • DNA-binding specificity of PAR and C/EBP leucine zipper proteins: A single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP
    • 65 Falvey E, Marcacci L, Schibler U. DNA-binding specificity of PAR and C/EBP leucine zipper proteins: a single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP. Biol Chem 1996;377: 797-809.
    • (1996) Biol Chem , vol.377 , pp. 797-809
    • Falvey, E.1    Marcacci, L.2    Schibler, U.3
  • 66
    • 0025162339 scopus 로고
    • HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally
    • 66 Lai E, Prezioso VR, Smith E, et al. HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev 1990;4:1427-36.
    • (1990) Genes Dev , vol.4 , pp. 1427-1436
    • Lai, E.1    Prezioso, V.R.2    Smith, E.3
  • 67
    • 0026083212 scopus 로고
    • Hepatocyte nuclear factor 3α belongs to a gene family in mammals that is homelogous to the Drosophila homeotic gene fork head
    • 67 Lai E, Prezioso VR, Tao W, et al. Hepatocyte nuclear factor 3α belongs to a gene family in mammals that is homelogous to the Drosophila homeotic gene fork head. Genes Dev 1991;5:416-27.
    • (1991) Genes Dev , vol.5 , pp. 416-427
    • Lai, E.1    Prezioso, V.R.2    Tao, W.3
  • 68
    • 0026672433 scopus 로고
    • Hepatocyte nuclear factor 3β contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein
    • 68 Pani L, Overdier DG, Porcella A, et al. Hepatocyte nuclear factor 3β contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein. Mol Cell Biol 1992;12:3723-32.
    • (1992) Mol Cell Biol , vol.12 , pp. 3723-3732
    • Pani, L.1    Overdier, D.G.2    Porcella, A.3
  • 69
    • 0028025566 scopus 로고
    • The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
    • 69 Weinstein DC, Altaba AR, Chen WS, et al. The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo. Cell 1994;78:575-88.
    • (1994) Cell , vol.78 , pp. 575-588
    • Weinstein, D.C.1    Altaba, A.R.2    Chen, W.S.3
  • 70
    • 0027425136 scopus 로고
    • The formation and maintenance of the definitive endoderm lineage in mouse: Involvement of HNF-3/forkhead proteins
    • 70 Ang SL, Weirds A, Wong D, et al. The formation and maintenance of the definitive endoderm lineage in mouse: involvement of HNF-3/forkhead proteins Development 1993;119:1301-15.
    • (1993) Development , vol.119 , pp. 1301-1315
    • Ang, S.L.1    Weirds, A.2    Wong, D.3
  • 71
    • 0027425313 scopus 로고
    • Postimplantation expression pattern indicates a role for the mouse forkhead/HNF-3α, β, γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm
    • 71 Monaghan AP, Kaestner KH, Grau E, et al. Postimplantation expression pattern indicates a role for the mouse forkhead/HNF-3α, β, γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 1993;119:567-78.
    • (1993) Development , vol.119 , pp. 567-578
    • Monaghan, A.P.1    Kaestner, K.H.2    Grau, E.3
  • 72
    • 0027408752 scopus 로고
    • Modulation of liver-specific transcriptions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close apposition
    • 72 Jackson DA, Rowader KE, Stevens K, et al. Modulation of liver-specific transcriptions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close apposition. Mol Cell Biol 1993;13:2401-10.
    • (1993) Mol Cell Biol , vol.13 , pp. 2401-2410
    • Jackson, D.A.1    Rowader, K.E.2    Stevens, K.3
  • 73
    • 0026555197 scopus 로고
    • A transcriptional hierarchy involved in mammalian cell type specification
    • 73 Kuo CJ, Conley PB, Chen L, et al. A transcriptional hierarchy involved in mammalian cell type specification. Nature 1992;355:457-61.
    • (1992) Nature , vol.355 , pp. 457-461
    • Kuo, C.J.1    Conley, P.B.2    Chen, L.3
  • 74
    • 0025813282 scopus 로고
    • The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology
    • 74 DiPersio CM, Jackson DA, Zaret KS. The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Mol Cell Biol 1991;11:4405-14.
    • (1991) Mol Cell Biol , vol.11 , pp. 4405-4414
    • DiPersio, C.M.1    Jackson, D.A.2    Zaret, K.S.3
  • 75
    • 0025058804 scopus 로고
    • Induction of albumin gene transcription in hepatocytes by extracellular matrix proteins
    • 75 Caron JM. Induction of albumin gene transcription in hepatocytes by extracellular matrix proteins. Mol Cell Biol 1990; 10:1239-43.
    • (1990) Mol Cell Biol , vol.10 , pp. 1239-1243
    • Caron, J.M.1
  • 76
    • 0027939978 scopus 로고
    • Signal transduction and cell fate specification during Caenorhabditis elegans vulval development
    • 76 Eisenmann DM, Kim SK. Signal transduction and cell fate specification during Caenorhabditis elegans vulval development. Curr Opin Genet Dev 1994;4:508-16
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 508-516
    • Eisenmann, D.M.1    Kim, S.K.2
  • 77
    • 0026516677 scopus 로고
    • The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor-3β involves a cell-specific factor and positive autoactivation
    • 77 Pani L, Clevidence DE, Qian X, et al. The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor-3β involves a cell-specific factor and positive autoactivation. Mol Cell Biol 1992;12:552-62.
    • (1992) Mol Cell Biol , vol.12 , pp. 552-562
    • Pani, L.1    Clevidence, D.E.2    Qian, X.3
  • 78
    • 0031017018 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-3α promoter regulation involves recognition by cell-specific factors, thyroid transcription factor-1, and autoactivation
    • 78 Peterson RS, Clevidence DE, Ye H, et al. Hepatocyte nuclear factor-3α promoter regulation involves recognition by cell-specific factors, thyroid transcription factor-1, and autoactivation. Cell Growth Differ 1997;8:69-82.
    • (1997) Cell Growth Differ , vol.8 , pp. 69-82
    • Peterson, R.S.1    Clevidence, D.E.2    Ye, H.3
  • 79
    • 0031938017 scopus 로고    scopus 로고
    • Alteration of expression of liver-enriched transcription factors in the transition between growth and differentiation of primary cultured rat hepatocytes
    • 79 Mizuguchi T, Mitaka T, Hirata K, et al. Alteration of expression of liver-enriched transcription factors in the transition between growth and differentiation of primary cultured rat hepatocytes. J Cell Physiol 1998;174:273-84.
    • (1998) J Cell Physiol , vol.174 , pp. 273-284
    • Mizuguchi, T.1    Mitaka, T.2    Hirata, K.3
  • 80
    • 0029841390 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain
    • 80 Lemaigre FP, Durviaux SM, Truong O, et al. Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain. Proc Natl Acad Sci USA 1996;93:9460-4.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9460-9464
    • Lemaigre, F.P.1    Durviaux, S.M.2    Truong, O.3
  • 81
    • 0029824047 scopus 로고    scopus 로고
    • The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression
    • 81 Samadani U, Costa RH. The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression. Mol Cell Biol 1996;16:6273-84.
    • (1996) Mol Cell Biol , vol.16 , pp. 6273-6284
    • Samadani, U.1    Costa, R.H.2
  • 82
    • 0031573874 scopus 로고    scopus 로고
    • HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates in the cross-regulatory network of liver-enriched transcription factors
    • 82 Landry C, Clotman F, Hioki T, et al. HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates in the cross-regulatory network of liver-enriched transcription factors. Dev Biol 1997;192: 247-57.
    • (1997) Dev Biol , vol.192 , pp. 247-257
    • Landry, C.1    Clotman, F.2    Hioki, T.3
  • 83
    • 0031573810 scopus 로고    scopus 로고
    • The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its gene HNF-3β in the developing murine liver and pancreas
    • 83 Rausa F, Samadani U, Ye H, et al. The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its gene HNF-3β in the developing murine liver and pancreas. Dev Biol 1997;192;228-46.
    • (1997) Dev Biol , vol.192 , pp. 228-246
    • Rausa, F.1    Samadani, U.2    Ye, H.3
  • 84
    • 0027546305 scopus 로고
    • Pathology and DNA cytophometry of small hepatocellular carcinoma with a nodule in nodule appearance - Evidence for stepwise progression of hepatocellular carcinoma
    • 84 Rim KS, Sakamoto M, Watanabe H, et al. Pathology and DNA cytophometry of small hepatocellular carcinoma with a nodule in nodule appearance - evidence for stepwise progression of hepatocellular carcinoma. Jpn J Clin Oncol 1992;23:26-33.
    • (1992) Jpn J Clin Oncol , vol.23 , pp. 26-33
    • Rim, K.S.1    Sakamoto, M.2    Watanabe, H.3
  • 85
    • 0029131938 scopus 로고
    • Pathomorphologic characteristics of small hepatocellular carcinoma: A special reference to small hepatocellular carcinoma with indistinct margins
    • 85 Nakashima O, Sugihara S, Kage M, et al. Pathomorphologic characteristics of small hepatocellular carcinoma: a special reference to small hepatocellular carcinoma with indistinct margins, Hepatology 1995;22:101-5.
    • (1995) Hepatology , vol.22 , pp. 101-105
    • Nakashima, O.1    Sugihara, S.2    Kage, M.3
  • 86
    • 0031059533 scopus 로고    scopus 로고
    • Stromal and blood vessel wall invasion in well-differentiated hepatocellular carcinoma
    • 86 Nakano M, Saito A, Yamamoto M, et al. Stromal and blood vessel wall invasion in well-differentiated hepatocellular carcinoma. Liver 1997;17:41-6.
    • (1997) Liver , vol.17 , pp. 41-46
    • Nakano, M.1    Saito, A.2    Yamamoto, M.3


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