-
2
-
-
0026019106
-
Erythropoietin
-
Krantz S.B. Erythropoietin. Blood. 77:1991;419-434
-
(1991)
Blood
, vol.77
, pp. 419-434
-
-
Krantz, S.B.1
-
3
-
-
0030044419
-
Epoetin beta. A review of its pharmacological properties and clinical use in the management of anaemia associated with chronic renal failure
-
Dunn C.J., Markham A. Epoetin beta. A review of its pharmacological properties and clinical use in the management of anaemia associated with chronic renal failure. Drugs. 51:1996;299-318
-
(1996)
Drugs
, vol.51
, pp. 299-318
-
-
Dunn, C.J.1
Markham, A.2
-
5
-
-
0037227316
-
Erythropoietin: Physiology and pharmacology update
-
Fisher J.W. Erythropoietin: physiology and pharmacology update. Exp. Biol Med. 228:2003;1-14
-
(2003)
Exp. Biol Med.
, vol.228
, pp. 1-14
-
-
Fisher, J.W.1
-
6
-
-
0037447256
-
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
-
Calvillo L., Latini R., Kajstura J., et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc. Natl. Acad. Sci. U. S. A. 100:2003;4802-4806
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 4802-4806
-
-
Calvillo, L.1
Latini, R.2
Kajstura, J.3
-
7
-
-
0038163900
-
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
-
Cai Z., Manalo D.J., Wei G., et al. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation. 108:2003;79-85
-
(2003)
Circulation
, vol.108
, pp. 79-85
-
-
Cai, Z.1
Manalo, D.J.2
Wei, G.3
-
8
-
-
85047691007
-
A novel protective effect of erythropoietin in the infarcted heart
-
Parsa C.J., Matsumoto A., Kim J., et al. A novel protective effect of erythropoietin in the infarcted heart. J. Clin. Invest. 112:2003;999-1007
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 999-1007
-
-
Parsa, C.J.1
Matsumoto, A.2
Kim, J.3
-
9
-
-
0041659121
-
Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway
-
Tramontano A.F., Muniyappa R., Black A.D., et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem. Biophys. Res. Commun. 2003;990-994
-
(2003)
Biochem. Biophys. Res. Commun.
, pp. 990-994
-
-
Tramontano, A.F.1
Muniyappa, R.2
Black, A.D.3
-
10
-
-
0141593556
-
Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
-
Moon C., Krawczyk M., Ahn D., et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc. Natl. Acad. Sci. U. S. A. 100:2003;11612-11617
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 11612-11617
-
-
Moon, C.1
Krawczyk, M.2
Ahn, D.3
-
11
-
-
0141888206
-
Researchers probe anemia - Heart failure link
-
Mitka M. Researchers probe anemia - heart failure link. JAMA. 290:2003;1835-1838
-
(2003)
JAMA
, vol.290
, pp. 1835-1838
-
-
Mitka, M.1
-
12
-
-
0034006016
-
HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
-
Semenza G.L. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J. Appl. Physiol. 88:2000;1474-1480
-
(2000)
J. Appl. Physiol.
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
13
-
-
0027956115
-
A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes
-
Masuda S., Okano M., Yamagishi K., et al. A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes. J. Biol. Chem. 269:1994;19488-19493
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19488-19493
-
-
Masuda, S.1
Okano, M.2
Yamagishi, K.3
-
14
-
-
0034013854
-
Neurons and astrocytes express EPO mRNA: Oxygen-sensing mechanisms that involve the redox-state of the brain
-
Bernaudin M., Bellail A., Marti H.H., et al. Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain. Glia. 30:2000;271-278
-
(2000)
Glia
, vol.30
, pp. 271-278
-
-
Bernaudin, M.1
Bellail, A.2
Marti, H.H.3
-
15
-
-
0027302375
-
Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells
-
Masuda S., Nagao M., Takahata K., et al. Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells. J. Biol. Chem. 268:1993;11208-11216
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11208-11216
-
-
Masuda, S.1
Nagao, M.2
Takahata, K.3
-
16
-
-
0035833541
-
Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
-
Digicaylioglu M., Lipton S.A. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature. 412:2001;641-647
-
(2001)
Nature
, vol.412
, pp. 641-647
-
-
Digicaylioglu, M.1
Lipton, S.A.2
-
17
-
-
0036896201
-
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: Evidence from an in vitro model
-
Ruscher K., Freyer D., Karsch M., et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J. Neurosci. 22:2002;10291-10301
-
(2002)
J. Neurosci.
, vol.22
, pp. 10291-10301
-
-
Ruscher, K.1
Freyer, D.2
Karsch, M.3
-
18
-
-
0042122371
-
Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin
-
Prass K., Scharff A., Ruscher K., et al. Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin. Stroke. 34:2003;1981-1986
-
(2003)
Stroke
, vol.34
, pp. 1981-1986
-
-
Prass, K.1
Scharff, A.2
Ruscher, K.3
-
19
-
-
0032516086
-
In vivo evidence that erythropoietin protects neurons from ischemic damage
-
Sakanaka M., Wen T.C., Matsuda S., et al. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc. Natl. Acad. Sci. U. S. A. 95:1998;4635-4640
-
(1998)
Proc. Natl. Acad . Sci. U. S. A.
, vol.95
, pp. 4635-4640
-
-
Sakanaka, M.1
Wen, T.C.2
Matsuda, S.3
-
20
-
-
0034641710
-
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
-
Brines M.L., Ghezzi P., Keenan S., et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc. Natl. Acad. Sci. U. S. A. 97:2000;10526-10531
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 10526-10531
-
-
Brines, M.L.1
Ghezzi, P.2
Keenan, S.3
-
21
-
-
0035957426
-
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
-
Siren A.L., Fratelli M., Brines M., et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4044-4049
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4044-4049
-
-
Siren, A.L.1
Fratelli, M.2
Brines, M.3
-
22
-
-
0037133191
-
Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
-
Celik M., Gokmen N., Erbayraktar S., et al. Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury. Proc. Natl. Acad. Sci. U. S. A. 99:2002;2258-2263
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 2258-2263
-
-
Celik, M.1
Gokmen, N.2
Erbayraktar, S.3
-
23
-
-
0023508493
-
Recombinant human erythropoietin therapy in haemodialysis patients - Dose determination and clinical experience
-
Bommer J., Alexiou C., Muller-Buhl U., Eifert J., Ritz E. Recombinant human erythropoietin therapy in haemodialysis patients - dose determination and clinical experience. Nephrol. Dial. Transplant. 2:1987;238-242
-
(1987)
Nephrol. Dial. Transplant.
, vol.2
, pp. 238-242
-
-
Bommer, J.1
Alexiou, C.2
Muller-Buhl, U.3
Eifert, J.4
Ritz, E.5
-
24
-
-
0024345845
-
Treatment of the anemia of progressive renal failure with recombinant human erythropoietin
-
Eschbach J.W., Kelly M.R., Haley N.R., Abels R.I., Adamson J.W. Treatment of the anemia of progressive renal failure with recombinant human erythropoietin. N. Engl. J. Med. 321:1989;158-163
-
(1989)
N. Engl. J. Med.
, vol.321
, pp. 158-163
-
-
Eschbach, J.W.1
Kelly, M.R.2
Haley, N.R.3
Abels, R.I.4
Adamson, J.W.5
-
25
-
-
0042889128
-
Once-weekly dosing of epoetin-alpha increases hemoglobin and improves quality of life in anemic cancer patients receiving radiation therapy either concomitantly or sequentially with chemotherapy
-
Shasha D., George M.J., Harrison L.B. Once-weekly dosing of epoetin-alpha increases hemoglobin and improves quality of life in anemic cancer patients receiving radiation therapy either concomitantly or sequentially with chemotherapy. Cancer. 98:2003;1072-1079
-
(2003)
Cancer
, vol.98
, pp. 1072-1079
-
-
Shasha, D.1
George, M.J.2
Harrison, L.B.3
-
26
-
-
0033996650
-
Intravenous recombinant erythropoietin does not lead to an increase in cerebrospinal fluid erythropoietin concentration
-
Buemi M., Allegra A., Corica F., et al. Intravenous recombinant erythropoietin does not lead to an increase in cerebrospinal fluid erythropoietin concentration. Nephrol. Dial. Transplant. 15:2000;422-423
-
(2000)
Nephrol. Dial. Transplant.
, vol.15
, pp. 422-423
-
-
Buemi, M.1
Allegra, A.2
Corica, F.3
-
27
-
-
0031037376
-
Detection of erythropoietin in human liquor: Intrinsic erythropoietin production in the brain
-
Marti H.H., Gassmann M., Wenger R.H., et al. Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain. Kidney Int. 51:1997;416-418
-
(1997)
Kidney Int.
, vol.51
, pp. 416-418
-
-
Marti, H.H.1
Gassmann, M.2
Wenger, R.H.3
-
28
-
-
0036705708
-
Erythropoietin therapy for acute stroke is both safe and beneficial
-
Ehrenreich H., Hasselblatt M., Dembowski C., et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol. Med. 8:2002;495-505
-
(2002)
Mol. Med.
, vol.8
, pp. 495-505
-
-
Ehrenreich, H.1
Hasselblatt, M.2
Dembowski, C.3
-
29
-
-
0030636320
-
Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death
-
Morishita E., Masuda S., Nagao M., Yasuda Y., Sasaki R. Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death. Neuroscience. 76:1997;105-116
-
(1997)
Neuroscience
, vol.76
, pp. 105-116
-
-
Morishita, E.1
Masuda, S.2
Nagao, M.3
Yasuda, Y.4
Sasaki, R.5
-
30
-
-
0037974734
-
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo
-
Erbayraktar S., Grasso G., Sfacteria A., et al. Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc. Natl. Acad. Sci. U. S. A. 100:2003;6741-6746
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 6741-6746
-
-
Erbayraktar, S.1
Grasso, G.2
Sfacteria, A.3
-
31
-
-
0034952544
-
Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin
-
Wiessner C., Allegrini P.R., Ekatodramis D., et al. Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin. J. Cereb. Blood Flow Metab. 21:2001;857-864
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 857-864
-
-
Wiessner, C.1
Allegrini, P.R.2
Ekatodramis, D.3
-
32
-
-
0036798849
-
Erythropoietin triggers a signaling pathway in endothelial cells and increases the thrombogenicity of their extracellular matrices in vitro
-
Fuste B., Serradell M., Escolar G., et al. Erythropoietin triggers a signaling pathway in endothelial cells and increases the thrombogenicity of their extracellular matrices in vitro. Thromb. Haemost. 88:2002;678-685
-
(2002)
Thromb. Haemost.
, vol.88
, pp. 678-685
-
-
Fuste, B.1
Serradell, M.2
Escolar, G.3
-
33
-
-
0030978397
-
Erythropoietin potentiates thrombus development in a canine arterio-venous shunt model
-
Wolf R.F., Gilmore L.S., Friese P., et al. Erythropoietin potentiates thrombus development in a canine arterio-venous shunt model. Thromb. Haemost. 77:1997;1020-1024
-
(1997)
Thromb. Haemost.
, vol.77
, pp. 1020-1024
-
-
Wolf, R.F.1
Gilmore, L.S.2
Friese, P.3
-
34
-
-
0032987496
-
Recombinant human erythropoietin inhibits iNOS activity and reverts vascular dysfunction in splanchnic artery occlusion shock
-
Squadrito F., Altavilla D., Squadrito G., et al. Recombinant human erythropoietin inhibits iNOS activity and reverts vascular dysfunction in splanchnic artery occlusion shock. Br. J. Pharmacol. 127:1999;482-488
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 482-488
-
-
Squadrito, F.1
Altavilla, D.2
Squadrito, G.3
-
35
-
-
0037117577
-
Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage
-
Grasso G., Buemi M., Alafaci C., et al. Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage. Proc. Natl. Acad. Sci. U. S. A. 99:2002;5627-5631
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5627-5631
-
-
Grasso, G.1
Buemi, M.2
Alafaci, C.3
-
36
-
-
0037016065
-
Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
-
Chong Z.Z., Kang J.-Q., Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation. 106:2002;2973-2979
-
(2002)
Circulation
, vol.106
, pp. 2973-2979
-
-
Chong, Z.Z.1
Kang, J.-Q.2
Maiese, K.3
-
37
-
-
0037064261
-
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
-
Agnello D., Bigini P., Villa P., et al. Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res. 952:2002;128-134
-
(2002)
Brain Res.
, vol.952
, pp. 128-134
-
-
Agnello, D.1
Bigini, P.2
Villa, P.3
-
38
-
-
0141784841
-
Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
-
Villa P., Bigini P., Mennini T., et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J. Exp. Med. 198:2003;971-975
-
(2003)
J. Exp. Med.
, vol.198
, pp. 971-975
-
-
Villa, P.1
Bigini, P.2
Mennini, T.3
-
39
-
-
0035894847
-
Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells
-
Shingo T., Sorokan S.T., Shimazaki T., Weiss S. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J. Neurosci. 21:2001;9733-9743
-
(2001)
J. Neurosci.
, vol.21
, pp. 9733-9743
-
-
Shingo, T.1
Sorokan, S.T.2
Shimazaki, T.3
Weiss, S.4
-
40
-
-
0035914398
-
Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
-
Kawakami M., Sekiguchi M., Sato K., Kozaki S., Takahashi M. Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J. Biol. Chem. 276:2001;39469-39475
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39469-39475
-
-
Kawakami, M.1
Sekiguchi, M.2
Sato, K.3
Kozaki, S.4
Takahashi, M.5
-
41
-
-
0034637297
-
Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation
-
Calapai G., Marciano M.C., Corica F., et al. Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation. Eur. J. Pharmacol. 401:2000;349-356
-
(2000)
Eur. J. Pharmacol.
, vol.401
, pp. 349-356
-
-
Calapai, G.1
Marciano, M.C.2
Corica, F.3
-
42
-
-
0028785505
-
Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity
-
Damen J.E., Cutler R.L., Jiao H., Yi T., Krystal G. Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity. J. Biol. Chem. 270:1995;23402-23408
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23402-23408
-
-
Damen, J.E.1
Cutler, R.L.2
Jiao, H.3
Yi, T.4
Krystal, G.5
-
43
-
-
1842288566
-
Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate: 2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation
-
Verdier F., Chretien S., Billat C., et al. Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate: 2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation. J. Biol. Chem. 272:1997;26173-26178
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26173-26178
-
-
Verdier, F.1
Chretien, S.2
Billat, C.3
-
44
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesbroeck B., Alessi D.R. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346:2000;561-576
-
(2000)
Biochem. J.
, vol.346
, pp. 561-576
-
-
Vanhaesbroeck, B.1
Alessi, D.R.2
-
45
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor M.A., Alessi D.R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114:2001;2903-2910
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
46
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; Comparison with MAPKAP kinase-1 and p70 S6 kinase
-
Alessi D.R., Caudwell F.B., Andjelkovic M., Hemmings B.A., Cohen P. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399:1996;333-338
-
(1996)
FEBS Lett.
, vol.399
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
47
-
-
0035072833
-
A motif-based profile scanning approach for genome-wide prediction of signaling pathways
-
Yaffe M.B., Leparc G.G., Lai J., et al. A motif-based profile scanning approach for genome-wide prediction of signaling pathways. Nat. Biotechnol. 19:2001;348-353
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 348-353
-
-
Yaffe, M.B.1
Leparc, G.G.2
Lai, J.3
-
48
-
-
0032543578
-
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136
-
Blume-Jensen P., Janknecht R., Hunter T. The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136. Curr. Biol. 8:1998;779-782
-
(1998)
Curr. Biol.
, vol.8
, pp. 779-782
-
-
Blume-Jensen, P.1
Janknecht, R.2
Hunter, T.3
-
49
-
-
0032808154
-
Akt/protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
-
Kennedy S.G., Kandel E.S., Cross T.K., Hay N. Akt/protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol. Cell. Biol. 19:1999;5800-5810
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5800-5810
-
-
Kennedy, S.G.1
Kandel, E.S.2
Cross, T.K.3
Hay, N.4
-
50
-
-
0037077230
-
Akt enhances Mdm2-mediated ubiquitination and degradation of p53
-
Ogawara Y., Kishishita S., Obata T., et al. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J. Biol. Chem. 277:2002;21843-21850
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21843-21850
-
-
Ogawara, Y.1
Kishishita, S.2
Obata, T.3
-
51
-
-
0035895964
-
Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53
-
Yamaguchi A., Tamatani M., Matsuzaki H., et al. Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. J. Biol. Chem. 276:2001;5256-5264
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5256-5264
-
-
Yamaguchi, A.1
Tamatani, M.2
Matsuzaki, H.3
-
52
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 288:2000;1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
-
53
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
54
-
-
0033621956
-
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
Chen C., Edelstein L.C., Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol. Cell. Biol. 20:2000;2687-2695
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
55
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
-
Zong W.X., Edelstein L.C., Chen C., Bash J., Gelinas C. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev. 13:1999;382-387
-
(1999)
Genes Dev.
, vol.13
, pp. 382-387
-
-
Zong, W.X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gelinas, C.5
-
56
-
-
0030885421
-
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
-
Chu Z.L., McKinsey T.A., Liu L., et al. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. Proc. Natl. Acad. Sci. U. S. A. 94:1997;10057-10062
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 10057-10062
-
-
Chu, Z.L.1
McKinsey, T.A.2
Liu, L.3
-
57
-
-
0027967063
-
Reperfusion injury induces apoptosis in rabbit cardiomyocytes
-
Gottlieb R.A., Burleson K.O., Kloner R.A., Babior B.M., Engler R.L. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J. Clin. Invest. 94:1994;1621-1628
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1621-1628
-
-
Gottlieb, R.A.1
Burleson, K.O.2
Kloner, R.A.3
Babior, B.M.4
Engler, R.L.5
-
58
-
-
0034649267
-
Progress in the treatment of acute coronary syndromes. A 50-year perspective (1950-2000)
-
Theroux P., Willersen J.T., Armstrong P.W. Progress in the treatment of acute coronary syndromes. A 50-year perspective (1950-2000). Circulation. 102:2000;IV2-IV13
-
(2000)
Circulation
, vol.102
, pp. 2-IV13
-
-
Theroux, P.1
Willersen, J.T.2
Armstrong, P.W.3
-
59
-
-
0024320314
-
A dose-dependent effect of recombinant erythropoietin on the reticulocyte population of rats
-
Eder H., Rosslenbroich B., Failing K. A dose-dependent effect of recombinant erythropoietin on the reticulocyte population of rats. Blut. 59:1989;184-187
-
(1989)
Blut
, vol.59
, pp. 184-187
-
-
Eder, H.1
Rosslenbroich, B.2
Failing, K.3
-
60
-
-
0042738942
-
Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
-
Heeschen C., Aicher A., Lehmann R., et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood. 102:2003;1340-1346
-
(2003)
Blood
, vol.102
, pp. 1340-1346
-
-
Heeschen, C.1
Aicher, A.2
Lehmann, R.3
-
61
-
-
9144258353
-
Erythropoietin regulates endothelial progenitor cells
-
Bahlmann F.H., DeGroot K., Spandau J.M., et al. Erythropoietin regulates endothelial progenitor cells. Blood. 103:2004;921-926
-
(2004)
Blood
, vol.103
, pp. 921-926
-
-
Bahlmann, F.H.1
Degroot, K.2
Spandau, J.M.3
-
62
-
-
0141816771
-
Erythropoietin as an angiogenic factor
-
Ribatti D., Vacca A., Roccaro A.M., Crivellato E., Presta M. Erythropoietin as an angiogenic factor. Eur. J. Clin. Invest. 33:2003;891-896
-
(2003)
Eur. J. Clin. Invest.
, vol.33
, pp. 891-896
-
-
Ribatti, D.1
Vacca, A.2
Roccaro, A.M.3
Crivellato, E.4
Presta, M.5
-
63
-
-
0033561341
-
Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
-
Ribatti D., Presta M., Vacca A., et al. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood. 93:1999;2627-2636
-
(1999)
Blood
, vol.93
, pp. 2627-2636
-
-
Ribatti, D.1
Presta, M.2
Vacca, A.3
-
64
-
-
0036384462
-
Erythropoietin and VEGF exhibit equal angiogenic potential
-
Jaquet K., Krause K., Tawakol-Khodai M., Geidel S., Kuck K.H. Erythropoietin and VEGF exhibit equal angiogenic potential. Microvasc. Res. 64:2002;326-333
-
(2002)
Microvasc. Res.
, vol.64
, pp. 326-333
-
-
Jaquet, K.1
Krause, K.2
Tawakol-Khodai, M.3
Geidel, S.4
Kuck, K.H.5
-
65
-
-
0036041422
-
Erythropoietin, anemia, and orthostatic hypotension: The evidence mounts
-
Rao S.V., Stamler J.S. Erythropoietin, anemia, and orthostatic hypotension: the evidence mounts. Clin. Auton. Res. 12:2002;141-143
-
(2002)
Clin. Auton. Res.
, vol.12
, pp. 141-143
-
-
Rao, S.V.1
Stamler, J.S.2
-
66
-
-
0343360868
-
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group
-
Hebert P.C., Wells G., Blajchman M.A., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N. Engl. J. Med. 340:1999;409-417
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 409-417
-
-
Hebert, P.C.1
Wells, G.2
Blajchman, M.A.3
-
67
-
-
0032572913
-
The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
-
Besarab A., Bolton W.K., Browne J.K., et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N. Engl. J. Med. 339:1998;584-590
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 584-590
-
-
Besarab, A.1
Bolton, W.K.2
Browne, J.K.3
-
68
-
-
0035863943
-
Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin
-
Wagner K.F., Katschinski D.M., Hasegawa J., et al. Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin. Blood. 97:2001;536-542
-
(2001)
Blood
, vol.97
, pp. 536-542
-
-
Wagner, K.F.1
Katschinski, D.M.2
Hasegawa, J.3
-
69
-
-
0346096546
-
Norepinephrine-induced acute heart failure in transgenic mice overexpressing erythropoietin
-
Deten A., Shibata J., Scholz D., et al. Norepinephrine-induced acute heart failure in transgenic mice overexpressing erythropoietin. Cardiovasc. Res. 61:2004;105-114
-
(2004)
Cardiovasc. Res.
, vol.61
, pp. 105-114
-
-
Deten, A.1
Shibata, J.2
Scholz, D.3
-
70
-
-
85048550370
-
Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice
-
Quaschning T., Ruschitzka F., Stallmach T., et al. Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice. FASEB J. 17:2003;259-261
-
(2003)
FASEB J.
, vol.17
, pp. 259-261
-
-
Quaschning, T.1
Ruschitzka, F.2
Stallmach, T.3
-
71
-
-
0036269528
-
Pharmacological possibilities for protection against myocardial reperfusion injury
-
Wang Q.D., Pernow J., Sjoquist P.O., Ryden L. Pharmacological possibilities for protection against myocardial reperfusion injury. Cardiovasc. Res. 55:2002;25-37
-
(2002)
Cardiovasc. Res.
, vol.55
, pp. 25-37
-
-
Wang, Q.D.1
Pernow, J.2
Sjoquist, P.O.3
Ryden, L.4
-
72
-
-
0042704727
-
Hypoxia rapidly activates HIF-3alpha mRNA expression
-
Heidbreder M., Frohlich F., Johren O., et al. Hypoxia rapidly activates HIF-3alpha mRNA expression. FASEB J. 17:2003;1541-1543
-
(2003)
FASEB J.
, vol.17
, pp. 1541-1543
-
-
Heidbreder, M.1
Frohlich, F.2
Johren, O.3
-
73
-
-
0033976342
-
Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes
-
Jung F., Palmer L.A., Zhou N., Johns R.A. Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes. Circ. Res. 86:2000;319-325
-
(2000)
Circ. Res.
, vol.86
, pp. 319-325
-
-
Jung, F.1
Palmer, L.A.2
Zhou, N.3
Johns, R.A.4
-
74
-
-
1642535393
-
Hepatic erythropoietin gene regulation by GATA-4
-
Dame C., Sola M.C., Lim K.C., et al. Hepatic erythropoietin gene regulation by GATA-4. J. Biol. Chem. 279:2004;2955-2961
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2955-2961
-
-
Dame, C.1
Sola, M.C.2
Lim, K.C.3
-
75
-
-
0037025326
-
The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
-
Dai Y.S., Cserjesi P., Markham B.E., Molkentin J.D. The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism. J. Biol. Chem. 277:2002;24390-24398
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24390-24398
-
-
Dai, Y.S.1
Cserjesi, P.2
Markham, B.E.3
Molkentin, J.D.4
-
76
-
-
0033534088
-
Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocyts in vitro
-
Matsui T., Li L., del Monte F., et al. Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocyts in vitro. Circulation. 100:1999;2373-2379
-
(1999)
Circulation
, vol.100
, pp. 2373-2379
-
-
Matsui, T.1
Li, L.2
Del Monte, F.3
-
77
-
-
0035902451
-
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
-
Matsui T., Tao J., del Monte F., et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation. 104:2001;330-335
-
(2001)
Circulation
, vol.104
, pp. 330-335
-
-
Matsui, T.1
Tao, J.2
Del Monte, F.3
-
78
-
-
0036772579
-
Elevated myocardial Akt signaling ameliorates doxorubicin-induced congestive heart failure and promotes heart growth
-
Taniyama Y., Walsh K. Elevated myocardial Akt signaling ameliorates doxorubicin-induced congestive heart failure and promotes heart growth. J. Mol. Cell. Cardiol. 34:2002;1241-1247
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 1241-1247
-
-
Taniyama, Y.1
Walsh, K.2
-
79
-
-
0032745819
-
Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes. Association with changes in mitochondrial membrane potential
-
Cook S.A., Sugden P.H., Clerk A. Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes. Association with changes in mitochondrial membrane potential. Circ. Res. 85:1999;940-949
-
(1999)
Circ. Res.
, vol.85
, pp. 940-949
-
-
Cook, S.A.1
Sugden, P.H.2
Clerk, A.3
-
80
-
-
0034704134
-
Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells
-
Wu W., Lee W.L., Wu Y.Y., et al. Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells. J. Biol. Chem. 275:2000;40113-40119
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40113-40119
-
-
Wu, W.1
Lee, W.L.2
Wu, Y.Y.3
-
81
-
-
0037151101
-
Transcriptional effects of chronic Akt activation in the heart
-
Cook S.A., Matsui T., Li L., Rosenzweig A. Transcriptional effects of chronic Akt activation in the heart. J. Biol. Chem. 277:2002;22528-22533
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22528-22533
-
-
Cook, S.A.1
Matsui, T.2
Li, L.3
Rosenzweig, A.4
-
82
-
-
0030666262
-
Molecular mechanisms for the control of translation by insulin
-
Proud C.G., Denton R.M. Molecular mechanisms for the control of translation by insulin. Biochem. J. 328:1997;329-341
-
(1997)
Biochem. J.
, vol.328
, pp. 329-341
-
-
Proud, C.G.1
Denton, R.M.2
-
83
-
-
0037177142
-
Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
-
Gao F., Gao E., Yue T.L., et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation. 105:2002;1497-1502
-
(2002)
Circulation
, vol.105
, pp. 1497-1502
-
-
Gao, F.1
Gao, E.2
Yue, T.L.3
-
84
-
-
0030036727
-
Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal protein kinases are activated by ischemia/reperfusion
-
Bogoyevitch M.A., Gillespie-Brown J., Ketterman A.J., et al. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal protein kinases are activated by ischemia/reperfusion. Circ. Res. 79:1996;162-173
-
(1996)
Circ. Res.
, vol.79
, pp. 162-173
-
-
Bogoyevitch, M.A.1
Gillespie-Brown, J.2
Ketterman, A.J.3
-
85
-
-
0037169526
-
Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation
-
Park H.S., Kim M.S., Huh S.H., et al. Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J. Biol. Chem. 277:2002;2573-2578
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2573-2578
-
-
Park, H.S.1
Kim, M.S.2
Huh, S.H.3
-
86
-
-
0033595720
-
Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9
-
Fujita E., Jinbo A., Matuzaki H., et al. Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9. Biochem. Biophys. Res. Commun. 264:1999;550-555
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 550-555
-
-
Fujita, E.1
Jinbo, A.2
Matuzaki, H.3
-
87
-
-
85047694494
-
A mechanistic role for cardiac myocyte apoptosis in heart failure
-
Wencker D., Chandra M., Nguyen K., et al. A mechanistic role for cardiac myocyte apoptosis in heart failure. J. Clin. Invest. 111:2003;1497-1504
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1497-1504
-
-
Wencker, D.1
Chandra, M.2
Nguyen, K.3
-
88
-
-
0037392297
-
Erythropoietin improves cardiac contractility in post-hypoxic mice
-
Sterin-Borda L., Barcelo A.C., Bozzini C.E. Erythropoietin improves cardiac contractility in post-hypoxic mice. Br. J. Haematol. 121:2003;180-186
-
(2003)
Br. J. Haematol.
, vol.121
, pp. 180-186
-
-
Sterin-Borda, L.1
Barcelo, A.C.2
Bozzini, C.E.3
-
89
-
-
0037443954
-
Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation
-
Stuckmann I., Evans S., Lasar A.B. Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation. Dev. Biol. 255:2003;334-349
-
(2003)
Dev. Biol.
, vol.255
, pp. 334-349
-
-
Stuckmann, I.1
Evans, S.2
Lasar, A.B.3
-
90
-
-
0029924757
-
Mitogenic effect of erythropoietin on neonatal rat cardiomyocytes: Signal transduction pathways
-
Wald M.R., Borda E.S., Sterin-Borda L. Mitogenic effect of erythropoietin on neonatal rat cardiomyocytes: signal transduction pathways. J. Cell. Physiol. 167:1996;461-468
-
(1996)
J. Cell. Physiol.
, vol.167
, pp. 461-468
-
-
Wald, M.R.1
Borda, E.S.2
Sterin-Borda, L.3
|