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Volumn 166, Issue 2, 2004, Pages 1053-1079

Polygenic Variation Maintained by Balancing Selection: Pleiotropy, Sex-Dependent Allelic Effects and G × E Interactions

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; DNA POLYMORPHISM; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENETIC ANALYSIS; GENETIC MODEL; GENETIC SELECTION; GENETIC TRAIT; GENETIC VARIABILITY; MULTIFACTORIAL INHERITANCE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; SEX DIFFERENCE;

EID: 1642379258     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.166.2.1053     Document Type: Article
Times cited : (194)

References (80)
  • 1
    • 0035108485 scopus 로고    scopus 로고
    • Inversion polymorphisms and nucleotide polymorphism: Lessons from Drosophila
    • ANDOLFATTO, P., F. DEPAULIS and A. NAVARRO, 2001 Inversion polymorphisms and nucleotide polymorphism: lessons from Drosophila. Genet. Res. 77: 1-8.
    • (2001) Genet. Res. , vol.77 , pp. 1-8
    • Andolfatto, P.1    Depaulis, F.2    Navarro, A.3
  • 2
    • 0022470005 scopus 로고
    • The maintenance of polygenic variation through a balance between mutation and stabilising selection
    • BARTON, N. H., 1986 The maintenance of polygenic variation through a balance between mutation and stabilising selection. Genet. Res. 47: 209-216.
    • (1986) Genet. Res. , vol.47 , pp. 209-216
    • Barton, N.H.1
  • 3
    • 0025259533 scopus 로고
    • Pleiotropic models of quantitative variation
    • BARTON, N. H., 1990 Pleiotropic models of quantitative variation. Genetics 124: 773-782.
    • (1990) Genetics , vol.124 , pp. 773-782
    • Barton, N.H.1
  • 4
    • 0033374429 scopus 로고    scopus 로고
    • Clines in polygenic traits
    • BARTON, N. H., 1999 Clines in polygenic traits. Genet. Res. 74: 223-236.
    • (1999) Genet. Res. , vol.74 , pp. 223-236
    • Barton, N.H.1
  • 5
    • 0024792701 scopus 로고
    • Evolutionary quantitative genetics: How little do we know?
    • BARTON, N. H., and M. TURELLI, 1989 Evolutionary quantitative genetics: How little do we know? Annu. Rev. Genet. 23: 337-370.
    • (1989) Annu. Rev. Genet. , vol.23 , pp. 337-370
    • Barton, N.H.1    Turelli, M.2
  • 6
    • 0346664358 scopus 로고    scopus 로고
    • The ecology of individuals: Incidence and implications of individual specialization
    • BOLNICK, D. I., R. SVÄNBACK, J. A. FORDYCE, L. H. YANG, J. M. DAVIS et al., 2003 The ecology of individuals: incidence and implications of individual specialization. Am. Nat. 161: 1-28.
    • (2003) Am. Nat. , vol.161 , pp. 1-28
    • Bolnick, D.I.1    Svänback, R.2    Fordyce, J.A.3    Yang, L.H.4    Davis, J.M.5
  • 7
    • 0015131426 scopus 로고
    • The stability of equilibria under selection
    • BULMER, M. G., 1971 The stability of equilibria under selection. Heredity 27: 157-162.
    • (1971) Heredity , vol.27 , pp. 157-162
    • Bulmer, M.G.1
  • 8
    • 0015810209 scopus 로고
    • The maintenance of the genetic variability of polygenic characters under heterozygote advantage
    • BULMER, M. G., 1973 The maintenance of the genetic variability of polygenic characters under heterozygote advantage. Genet. Res. 22: 9-12.
    • (1973) Genet. Res. , vol.22 , pp. 9-12
    • Bulmer, M.G.1
  • 9
    • 0002390244 scopus 로고
    • Density-dependent selection and character displacement
    • BULMER, M. G., 1974 Density-dependent selection and character displacement. Am. Nat. 108: 45-58.
    • (1974) Am. Nat. , vol.108 , pp. 45-58
    • Bulmer, M.G.1
  • 10
    • 0344993925 scopus 로고    scopus 로고
    • Evolution of genetic variability and the advantage of sex and recombination in changing environments
    • BÜRGER, R., 1999 Evolution of genetic variability and the advantage of sex and recombination in changing environments. Genetics 153: 1055-1069.
    • (1999) Genetics , vol.153 , pp. 1055-1069
    • Bürger, R.1
  • 12
    • 0036830161 scopus 로고    scopus 로고
    • On a genetic model of intraspecific competition and stabilizing selection
    • BÜRGER, R., 2002 On a genetic model of intraspecific competition and stabilizing selection. Am. Nat. 160: 661-682.
    • (2002) Am. Nat. , vol.160 , pp. 661-682
    • Bürger, R.1
  • 13
    • 0344689836 scopus 로고    scopus 로고
    • Genetic variation maintained in multilocus models of additive quantitative traits under stabilizing selection
    • BÜRGER, R., and A. GIMELFARB, 1999 Genetic variation maintained in multilocus models of additive quantitative traits under stabilizing selection. Genetics 152: 809-820.
    • (1999) Genetics , vol.152 , pp. 809-820
    • Bürger, R.1    Gimelfarb, A.2
  • 14
    • 0036694885 scopus 로고    scopus 로고
    • Fluctuating environments and the role of mutation in maintaining quantitative genetic variation
    • BÜRGER, R., and A. GIMELFARB, 2002 Fluctuating environments and the role of mutation in maintaining quantitative genetic variation. Genet. Res. 80: 31-46.
    • (2002) Genet. Res. , vol.80 , pp. 31-46
    • Bürger, R.1    Gimelfarb, A.2
  • 15
    • 0027945336 scopus 로고
    • A pleiotropic non-additive model of variation in quantitative traits
    • CABALLERO, A., and P. D. KEIGHTLEY, 1994 A pleiotropic non-additive model of variation in quantitative traits. Genetics 138: 883-900.
    • (1994) Genetics , vol.138 , pp. 883-900
    • Caballero, A.1    Keightley, P.D.2
  • 16
    • 0000823129 scopus 로고    scopus 로고
    • The maintenance of genetic variation in life-history traits
    • edited by R. S. Singh and C. B. Krimbas. Cambridge University Press, Cambridge, UK/London/New York
    • CHARLESWORTH, B., and K. A. HUGHES, 2000 The maintenance of genetic variation in life-history traits, pp. 369-392 in Evolutionary Genetics: From Molecules to Morphology, Vol. 1, edited by R. S. SINGH and C. B. KRIMBAS. Cambridge University Press, Cambridge, UK/London/New York.
    • (2000) Evolutionary Genetics: From Molecules to Morphology , vol.1 , pp. 369-392
    • Charlesworth, B.1    Hughes, K.A.2
  • 17
    • 0028042052 scopus 로고
    • Pleiotropy, reversal of dominance, and genetic polymorphism
    • CURTSINGER, J. W., P. M. SERVICE and T. PROUT, 1994 Pleiotropy, reversal of dominance, and genetic polymorphism. Am. Nat. 144: 210-228.
    • (1994) Am. Nat. , vol.144 , pp. 210-228
    • Curtsinger, J.W.1    Service, P.M.2    Prout, T.3
  • 19
    • 0036959393 scopus 로고    scopus 로고
    • The genetic architecture of Drosophila sensory bristle number
    • DILDA, C. L., and T. F. C. MACKAY, 2002 The genetic architecture of Drosophila sensory bristle number. Genetics 162: 1655-1674.
    • (2002) Genetics , vol.162 , pp. 1655-1674
    • Dilda, C.L.1    Mackay, T.F.C.2
  • 22
    • 0028317159 scopus 로고
    • Maintenance of multilocus variability under strong stabilizing selection
    • GAVRILETS, S., and A. HASTINGS, 1994 Maintenance of multilocus variability under strong stabilizing selection. J. Math. Biol. 32: 287-302.
    • (1994) J. Math. Biol. , vol.32 , pp. 287-302
    • Gavrilets, S.1    Hastings, A.2
  • 23
    • 0001258794 scopus 로고
    • Polymorphisms in random environments
    • GILLESPIE, J. H., 1974 Polymorphisms in random environments. Theor. Popul. Biol. 4: 193-195.
    • (1974) Theor. Popul. Biol. , vol.4 , pp. 193-195
    • Gillespie, J.H.1
  • 24
    • 0021180012 scopus 로고
    • Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters
    • GILLESPIE, J. H., 1984 Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters. Genetics 107: 321-330.
    • (1984) Genetics , vol.107 , pp. 321-330
    • Gillespie, J.H.1
  • 25
    • 0009212233 scopus 로고
    • The effects of environmental autocorrelations on the progress of selection in a random environment
    • GILLESPIE, J. H., and H. A. GUESS, 1978 The effects of environmental autocorrelations on the progress of selection in a random environment. Am. Nat. 112: 897-910.
    • (1978) Am. Nat. , vol.112 , pp. 897-910
    • Gillespie, J.H.1    Guess, H.A.2
  • 26
    • 0017235517 scopus 로고
    • Multilocus behavior in random environments. I. Random Levene models
    • GILLESPIE, J., and C. LANGLEY, 1976 Multilocus behavior in random environments. I. Random Levene models. Genetics 82: 123-137.
    • (1976) Genetics , vol.82 , pp. 123-137
    • Gillespie, J.1    Langley, C.2
  • 27
    • 0024495795 scopus 로고
    • Genotype-environment interactions and the maintenance of polygenic variation
    • GILLESPIE, J. H., and M. TURELLI, 1989 Genotype-environment interactions and the maintenance of polygenic variation. Genetics 121: 129-138.
    • (1989) Genetics , vol.121 , pp. 129-138
    • Gillespie, J.H.1    Turelli, M.2
  • 28
    • 0025019462 scopus 로고
    • Genotype-environment interactions: A reply
    • GILLESPIE, J. H., and M. TURELLI, 1990 Genotype-environment interactions: a reply. Genetics 124: 447.
    • (1990) Genetics , vol.124 , pp. 447
    • Gillespie, J.H.1    Turelli, M.2
  • 29
    • 0024423474 scopus 로고
    • Genotypic variation for a quantitative character maintained under stabilizing selection without mutations: Epistasis
    • GIMELFARB, A., 1989 Genotypic variation for a quantitative character maintained under stabilizing selection without mutations: epistasis. Genetics 123: 217-227.
    • (1989) Genetics , vol.123 , pp. 217-227
    • Gimelfarb, A.1
  • 30
    • 0025137872 scopus 로고
    • How much genetic variation can be maintained by genotype-environment interactions?
    • GIMELFARB, A., 1990 How much genetic variation can be maintained by genotype-environment interactions? Genetics 124: 443-445.
    • (1990) Genetics , vol.124 , pp. 443-445
    • Gimelfarb, A.1
  • 31
    • 0026567308 scopus 로고
    • Pleiotropy and multilocus polymorphisms
    • GIMELFARB, A., 1992 Pleiotropy and multilocus polymorphisms. Genetics 130: 223-227.
    • (1992) Genetics , vol.130 , pp. 223-227
    • Gimelfarb, A.1
  • 32
    • 0030276821 scopus 로고    scopus 로고
    • Some additional results about polymorphisms in models of an additive quantitative trait under stabilizing selection
    • GIMELFARB, A., 1996 Some additional results about polymorphisms in models of an additive quantitative trait under stabilizing selection. J. Math. Biol. 35: 88-96.
    • (1996) J. Math. Biol. , vol.35 , pp. 88-96
    • Gimelfarb, A.1
  • 33
    • 0031902270 scopus 로고    scopus 로고
    • Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster
    • GURGANUS, M. C., J. D. FRY, S. V. NUZHDIN, E. G. PASYUKOVA, R. F. LYMAN et al., 1998 Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster. Genetics 149: 1883-1898.
    • (1998) Genetics , vol.149 , pp. 1883-1898
    • Gurganus, M.C.1    Fry, J.D.2    Nuzhdin, S.V.3    Pasyukova, E.G.4    Lyman, R.F.5
  • 34
    • 0344747918 scopus 로고
    • A mathematical theory of natural and artificial selection. III
    • HALDANE, J. B. S., 1926 A mathematical theory of natural and artificial selection, III. Camb. Philos. Soc. Proc. 23: 363-372.
    • (1926) Camb. Philos. Soc. Proc. , vol.23 , pp. 363-372
    • Haldane, J.B.S.1
  • 35
    • 0036157464 scopus 로고    scopus 로고
    • Complex signatures of natural selection at the Duffy blood group locus
    • HAMBLIN, M. T., E. E. THOMPSON and A. DI RIENZO, 2002 Complex signatures of natural selection at the Duffy blood group locus. Am. J. Hum. Genet. 70: 369-383.
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 369-383
    • Hamblin, M.T.1    Thompson, E.E.2    Di Rienzo, A.3
  • 36
    • 0024354727 scopus 로고
    • Pleiotropic stabilizing selection limits the number of pleiotropic loci to at most the number of characters
    • HASTINGS, A., and C. L. HOM, 1989 Pleiotropic stabilizing selection limits the number of pleiotropic loci to at most the number of characters. Genetics 122: 459-463.
    • (1989) Genetics , vol.122 , pp. 459-463
    • Hastings, A.1    Hom, C.L.2
  • 37
    • 0000648593 scopus 로고
    • Multiple equilibria and maintenance of additive genetic variance in a model of pleiotropy
    • HASTINGS, A., and C. L. HOM, 1990 Multiple equilibria and maintenance of additive genetic variance in a model of pleiotropy. Evolution 44: 1153-1163.
    • (1990) Evolution , vol.44 , pp. 1153-1163
    • Hastings, A.1    Hom, C.L.2
  • 38
    • 0038104682 scopus 로고    scopus 로고
    • Epistasis in polygenic traits and the evolution of genetic architecture under stabilizing selection
    • HERMISSON, J., T. F. HANSEN and G. P. WAGNER, 2003 Epistasis in polygenic traits and the evolution of genetic architecture under stabilizing selection. Am. Nat. 161: 708-734.
    • (2003) Am. Nat. , vol.161 , pp. 708-734
    • Hermisson, J.1    Hansen, T.F.2    Wagner, G.P.3
  • 39
    • 0023339852 scopus 로고
    • A test for neutral molecular evolution based on nucleotide data
    • HUDSON, R. R., M. KREITMAN and M. AGUADE, 1987 A test for neutral molecular evolution based on nucleotide data. Genetics 116: 153-159.
    • (1987) Genetics , vol.116 , pp. 153-159
    • Hudson, R.R.1    Kreitman, M.2    Aguade, M.3
  • 41
    • 0015348065 scopus 로고
    • Polymorphisms for genetic and ecological systems with weak coupling
    • KARLIN, S., and J. MCGREGOR, 1972 Polymorphisms for genetic and ecological systems with weak coupling. Theor. Popul. Biol. 3: 210-238.
    • (1972) Theor. Popul. Biol. , vol.3 , pp. 210-238
    • Karlin, S.1    McGregor, J.2
  • 42
    • 0017354727 scopus 로고
    • Regions of stable equilibria for models with differential selection in the two sexes under random mating
    • KIDWELL, M. G., M. T. CLEGG, F. M. STEWART and T. PROUT, 1977 Regions of stable equilibria for models with differential selection in the two sexes under random mating. Genetics 85: 171-183.
    • (1977) Genetics , vol.85 , pp. 171-183
    • Kidwell, M.G.1    Clegg, M.T.2    Stewart, F.M.3    Prout, T.4
  • 44
    • 0031090405 scopus 로고    scopus 로고
    • Multilocus dynamics under haploid selection
    • KIRZHNER, V., and Y. LYUBICH, 1997 Multilocus dynamics under haploid selection. J. Math. Biol. 35: 391.
    • (1997) J. Math. Biol. , vol.35 , pp. 391
    • Kirzhner, V.1    Lyubich, Y.2
  • 45
    • 0029842292 scopus 로고    scopus 로고
    • High genetic variability under the balance between symmetric mutation and fluctuating stabilizing selection
    • KONDRASHOV, A. S., and L. Y. YAMPOLSKY, 1996 High genetic variability under the balance between symmetric mutation and fluctuating stabilizing selection. Genet. Res. 68: 157-164.
    • (1996) Genet. Res. , vol.68 , pp. 157-164
    • Kondrashov, A.S.1    Yampolsky, L.Y.2
  • 46
    • 0028578184 scopus 로고
    • Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster
    • LAI, C., R. F. LYMAN, A. D. LONG, C. H. LANGLEY and T. F. C. MACKAY, 1995 Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster. Science 266: 1697-1702.
    • (1995) Science , vol.266 , pp. 1697-1702
    • Lai, C.1    Lyman, R.F.2    Long, A.D.3    Langley, C.H.4    Mackay, T.F.C.5
  • 47
    • 0016814243 scopus 로고
    • The maintenance of genetic variability by mutation in a polygenic character with linked loci
    • LANDE, R., 1975 The maintenance of genetic variability by mutation in a polygenic character with linked loci. Genet. Res. 26: 221-235.
    • (1975) Genet. Res. , vol.26 , pp. 221-235
    • Lande, R.1
  • 48
    • 0001493328 scopus 로고
    • Genetic equilibrium when more than one ecological niche is available
    • LEVENE, H., 1953 Genetic equilibrium when more than one ecological niche is available. Am. Nat. 87: 331-333.
    • (1953) Am. Nat. , vol.87 , pp. 331-333
    • Levene, H.1
  • 49
    • 0030465899 scopus 로고    scopus 로고
    • Genetic interactions between naturally occurring alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila melanogaster
    • LONG, A. D., S. L. MULLANEY, T. F. C. MACKAY and C. H. LANGLEY, 1996 Genetic interactions between naturally occurring alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila melanogaster. Genetics 144: 1497-1510.
    • (1996) Genetics , vol.144 , pp. 1497-1510
    • Long, A.D.1    Mullaney, S.L.2    Mackay, T.F.C.3    Langley, C.H.4
  • 50
    • 0034056305 scopus 로고    scopus 로고
    • Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete-scute complex are associated with variation in bristle number in Drosophila melanogaster
    • LONG, A. D., R. F. LYMAN, A. H. MORGAN, C. H. LANGLEY and T. F. C. MACKAY, 2000 Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete-scute complex are associated with variation in bristle number in Drosophila melanogaster. Genetics 54: 1255-1269.
    • (2000) Genetics , vol.54 , pp. 1255-1269
    • Long, A.D.1    Lyman, R.F.2    Morgan, A.H.3    Langley, C.H.4    Mackay, T.F.C.5
  • 51
    • 0025123985 scopus 로고
    • Molecular and phenotypic variation in the achaete-scute region of Drosophila melanogaster
    • MACKAY, T. F. C., and C. H. LANGLEY, 1990 Molecular and phenotypic variation in the achaete-scute region of Drosophila melanogaster. Nature 348: 64-66.
    • (1990) Nature , vol.348 , pp. 64-66
    • Mackay, T.F.C.1    Langley, C.H.2
  • 52
    • 0018681923 scopus 로고
    • Selection in dioecious populations
    • NAGYLAKI, T., 1979 Selection in dioecious populations. Ann. Hum. Genet. 43: 143-150.
    • (1979) Ann. Hum. Genet. , vol.43 , pp. 143-150
    • Nagylaki, T.1
  • 53
    • 0024558263 scopus 로고
    • The maintenance of quantitative genetic variation in two-locus models of stabilizing selection
    • NAGYLAKI, T., 1989 The maintenance of quantitative genetic variation in two-locus models of stabilizing selection. Genetics 122: 235-248.
    • (1989) Genetics , vol.122 , pp. 235-248
    • Nagylaki, T.1
  • 54
    • 0035989435 scopus 로고    scopus 로고
    • The effects of multilocus balancing selection on neutral variability
    • NAVARRO, A., and N. H. BARTON, 2002 The effects of multilocus balancing selection on neutral variability. Genetics 161: 849-863.
    • (2002) Genetics , vol.161 , pp. 849-863
    • Navarro, A.1    Barton, N.H.2
  • 56
    • 0034025692 scopus 로고    scopus 로고
    • Adaptation and the cost of complexity
    • ORR, H. A., 2000 Adaptation and the cost of complexity. Evolution 54: 13-20.
    • (2000) Evolution , vol.54 , pp. 13-20
    • Orr, H.A.1
  • 57
    • 1642316716 scopus 로고
    • Synthesis
    • edited by S. J. Geerts. Pergamon Press, Oxford
    • ROBERTSON, A., 1965 Synthesis, pp. 527-532 in Genetics Today, Vol. 3, edited by S. J. GEERTS. Pergamon Press, Oxford.
    • (1965) Genetics Today , vol.3 , pp. 527-532
    • Robertson, A.1
  • 58
    • 84966160050 scopus 로고
    • Antagonistic pleiotropy, dominance, and genetic variation
    • ROSE, M. R., 1982 Antagonistic pleiotropy, dominance, and genetic variation. Heredity 48: 63-78.
    • (1982) Heredity , vol.48 , pp. 63-78
    • Rose, M.R.1
  • 59
    • 0028011209 scopus 로고
    • Dynamics of the two-locus haploid model
    • RUTSCHMAN, D. H., 1994 Dynamics of the two-locus haploid model. Theor. Popul. Biol. 45: 167-176.
    • (1994) Theor. Popul. Biol. , vol.45 , pp. 167-176
    • Rutschman, D.H.1
  • 60
    • 0037167852 scopus 로고    scopus 로고
    • Detecting recent positive selection in the human genome from haplotype structure
    • SABETI, P. C., D. REICH, J. M. HIGGINS, H. Z. P. LEVINE, D. J. RICHTER et al., 2002 Detecting recent positive selection in the human genome from haplotype structure. Nature 419: 832-837.
    • (2002) Nature , vol.419 , pp. 832-837
    • Sabeti, P.C.1    Reich, D.2    Higgins, J.M.3    Levine, H.Z.P.4    Richter, D.J.5
  • 61
    • 0028872553 scopus 로고
    • Quantitative genetics of response to competitors in Nemophila menziesii: A field experiment
    • SHAW, R. G., G. A. J. PLATENKAMP, F. H. SHAW and R. H. PODOLSKY, 1995 Quantitative genetics of response to competitors in Nemophila menziesii: a field experiment. Genetics 139: 397-406.
    • (1995) Genetics , vol.139 , pp. 397-406
    • Shaw, R.G.1    Platenkamp, G.A.J.2    Shaw, F.H.3    Podolsky, R.H.4
  • 62
    • 0032734337 scopus 로고    scopus 로고
    • Quantitative trait loci affecting survival and fertility-related traits in Caenorhabditis elegans show genotype-environment interactions, pleiotropy and epistasis
    • SHOOK, D. R., and T. E. JOHNSON, 1999 Quantitative trait loci affecting survival and fertility-related traits in Caenorhabditis elegans show genotype-environment interactions, pleiotropy and epistasis. Genetics 153: 1233-1243.
    • (1999) Genetics , vol.153 , pp. 1233-1243
    • Shook, D.R.1    Johnson, T.E.2
  • 63
    • 0018563643 scopus 로고
    • Frequency- and density-dependent selection on a quantitative character
    • SLATKIN, M., 1979 Frequency- and density-dependent selection on a quantitative character. Genetics 93: 755-771.
    • (1979) Genetics , vol.93 , pp. 755-771
    • Slatkin, M.1
  • 64
    • 0025232697 scopus 로고
    • The quantitative genetic consequences of pleiotropy under stabilizing and directional selection
    • SLATKIN, M., and S. A. FRANK, 1990 The quantitative genetic consequences of pleiotropy under stabilizing and directional selection. Genetics 125: 207-213.
    • (1990) Genetics , vol.125 , pp. 207-213
    • Slatkin, M.1    Frank, S.A.2
  • 65
    • 0021419667 scopus 로고
    • Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle
    • TURELLI, M., 1984 Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theor. Popul. Biol. 25: 138-193.
    • (1984) Theor. Popul. Biol. , vol.25 , pp. 138-193
    • Turelli, M.1
  • 66
    • 0022233074 scopus 로고
    • Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits
    • TURELLI, M., 1985 Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits. Genetics 111: 165-195.
    • (1985) Genetics , vol.111 , pp. 165-195
    • Turelli, M.1
  • 67
    • 0002225567 scopus 로고
    • Population genetic models for polygenic variation and evolution
    • edited by B. S. Weir, E. J. Eisen, M. M. Goodman and G. Namkoong. Sinauer, Sunderland, MA
    • TURELLI, M., 1988 Population genetic models for polygenic variation and evolution, pp. 601-618 in Proceedings of the Second International Conference on Quantitative Genetics, edited by B. S. WEIR, E. J. EISEN, M. M. GOODMAN and G. NAMKOONG. Sinauer, Sunderland, MA.
    • (1988) Proceedings of the Second International Conference on Quantitative Genetics , pp. 601-618
    • Turelli, M.1
  • 68
    • 0001065304 scopus 로고
    • Rate tests for selection on quantitative characters during macroevolution and microevolution
    • TURELLI, M., J. H. GILLESPIE and R. LANDE, 1988 Rate tests for selection on quantitative characters during macroevolution and microevolution. Evolution 42: 1085-1089.
    • (1988) Evolution , vol.42 , pp. 1085-1089
    • Turelli, M.1    Gillespie, J.H.2    Lande, R.3
  • 69
    • 0023319788 scopus 로고
    • Evolution of genetic variability in a spatially heterogeneous environment: Effects of genotype-environment interaction
    • VIA, S., and R. LANDE, 1987 Evolution of genetic variability in a spatially heterogeneous environment: effects of genotype-environment interaction. Genet. Res. 49: 147-156.
    • (1987) Genet. Res. , vol.49 , pp. 147-156
    • Via, S.1    Lande, R.2
  • 70
    • 0033979887 scopus 로고    scopus 로고
    • Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster
    • VIEIRA, C., E. G. PASYUKOVA, Z-B. ZENG, J. B. HACKETT, R. F. LYMAN et al., 2000 Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster. Genetics 154: 213-227.
    • (2000) Genetics , vol.154 , pp. 213-227
    • Vieira, C.1    Pasyukova, E.G.2    Zeng, Z.-B.3    Hackett, J.B.4    Lyman, R.F.5
  • 71
    • 0024523744 scopus 로고
    • Multivariate mutation-selection balance with constrained pleiotropic effects
    • WAGNER, G. P., 1989 Multivariate mutation-selection balance with constrained pleiotropic effects. Genetics 122: 223-234.
    • (1989) Genetics , vol.122 , pp. 223-234
    • Wagner, G.P.1
  • 72
    • 0038620463 scopus 로고    scopus 로고
    • The balance between pleiotropic mutation and selection, when alleles have discrete effects
    • WAXMAN, D., 2003 The balance between pleiotropic mutation and selection, when alleles have discrete effects. Theor. Popul. Biol. 63: 105-114.
    • (2003) Theor. Popul. Biol. , vol.63 , pp. 105-114
    • Waxman, D.1
  • 73
    • 0032845950 scopus 로고    scopus 로고
    • Sex and adaptation in a changing environment
    • WAXMAN, D., and J. R. PECK, 1999 Sex and adaptation in a changing environment. Genetics 153: 1041-1053.
    • (1999) Genetics , vol.153 , pp. 1041-1053
    • Waxman, D.1    Peck, J.R.2
  • 74
    • 0031883577 scopus 로고    scopus 로고
    • Quantitative genetics of ovariole number in Drosophila melanogaster: II. Mutational variance and genotype-environment interaction
    • WAYNE, M. L., and T. F. C. MACKAY, 1998 Quantitative genetics of ovariole number in Drosophila melanogaster: II. Mutational variance and genotype-environment interaction. Genetics 148: 201-210.
    • (1998) Genetics , vol.148 , pp. 201-210
    • Wayne, M.L.1    Mackay, T.F.C.2
  • 75
    • 0030301370 scopus 로고    scopus 로고
    • Natural heritabilities: Can they be reliably estimated in the laboratory?
    • WEIGENSBERG, I., and D. A. ROFF, 1996 Natural heritabilities: Can they be reliably estimated in the laboratory? Evolution 50: 2149-2157.
    • (1996) Evolution , vol.50 , pp. 2149-2157
    • Weigensberg, I.1    Roff, D.A.2
  • 76
    • 77951515648 scopus 로고
    • Evolution of populations in approximate equilibrium
    • WRIGHT, S., 1935 Evolution of populations in approximate equilibrium. J. Genet. 30: 257-266.
    • (1935) J. Genet. , vol.30 , pp. 257-266
    • Wright, S.1
  • 77
    • 0001111820 scopus 로고
    • The distribution of gene frequencies in populations
    • WRIGHT, S., 1937 The distribution of gene frequencies in populations. Proc. Natl. Acad. Sci. USA 23: 307-320.
    • (1937) Proc. Natl. Acad. Sci. USA , vol.23 , pp. 307-320
    • Wright, S.1
  • 78
    • 84996367494 scopus 로고
    • Genotype by environment interaction and genetic correlation of the same trait under different environments
    • YAMADA, Y., 1962 Genotype by environment interaction and genetic correlation of the same trait under different environments. Jpn. J. Genet. 37: 498-509.
    • (1962) Jpn. J. Genet. , vol.37 , pp. 498-509
    • Yamada, Y.1
  • 79
    • 0036743347 scopus 로고    scopus 로고
    • Joint effects of pleiotropic selection and stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance
    • ZHANG, X.-S., and W. G. HILL, 2002 Joint effects of pleiotropic selection and stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance. Genetics 162: 459-471.
    • (2002) Genetics , vol.162 , pp. 459-471
    • Zhang, X.-S.1    Hill, W.G.2
  • 80
    • 0027008226 scopus 로고
    • Quantitative variability and multilocus polymorphism under epistatic selection
    • ZHIVOTOVSKY, L., and S. GAVRILETS, 1992 Quantitative variability and multilocus polymorphism under epistatic selection. Theor. Popul. Biol. 42: 254-283.
    • (1992) Theor. Popul. Biol. , vol.42 , pp. 254-283
    • Zhivotovsky, L.1    Gavrilets, S.2


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