-
1
-
-
0032811658
-
Selective killing of cancer cells based on loss of heterozygosity and normal variation in the human genome: A new paradigm for anticancer drug therapy
-
BASILION, J.P., SCHIEVELLA, A.R., BURNS, E., RIOUS, P., OLSON, J.C., MONIA, B.P., LEMONIDIS, K.M., STANTON, V.P., and, HOUSMAN, D.E. (1999). Selective killing of cancer cells based on loss of heterozygosity and normal variation in the human genome: A new paradigm for anticancer drug therapy. Mol. Pharmacol. 56, 359-369.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 359-369
-
-
Basilion, J.P.1
Schievella, A.R.2
Burns, E.3
Rious, P.4
Olson, J.C.5
Monia, B.P.6
Lemonidis, K.M.7
Stanton, V.P.8
Housman, D.E.9
-
2
-
-
0346850835
-
Structural rearrangements of the 10-23 DNAzyme to beta 3 integrin subunit mRNA induced by cations and their relations to the catalytic activity
-
CIESLAK, M., SZYMANSKI, J., ADAMIAK, R.W., and CIERNIEWSKI, C.S. (2003). Structural rearrangements of the 10-23 DNAzyme to beta 3 integrin subunit mRNA induced by cations and their relations to the catalytic activity. J. Biol. Chem. 278, 47987-47996.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47987-47996
-
-
Cieslak, M.1
Szymanski, J.2
Adamiak, R.W.3
Cierniewski, C.S.4
-
3
-
-
2342459633
-
Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth
-
FAHMY, R.G., and KHACHIGIAN, L.M. (2004). Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth. Nucleic Acids Res. 32, 2281-2285.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2281-2285
-
-
Fahmy, R.G.1
Khachigian, L.M.2
-
4
-
-
0035914482
-
A new and efficient DNA enzyme for the sequence specific cleavage of RNA
-
FELDMAN, A.R., and SEN, D. (2001). A new and efficient DNA enzyme for the sequence specific cleavage of RNA. J. Mol. Biol. 313, 283-294.
-
(2001)
J. Mol. Biol.
, vol.313
, pp. 283-294
-
-
Feldman, A.R.1
Sen, D.2
-
5
-
-
0037600640
-
Killing cancer by targeting genes that cancer cells have lost: Allele-specific inhibition, a novel approach to the treatment of genetic disorders
-
FLUITER, K., HOUSMAN, D., TEN ASBROEK, A.L.M.A., and BAAS, F. (2003a). Killing cancer by targeting genes that cancer cells have lost: Allele-specific inhibition, a novel approach to the treatment of genetic disorders. Cell. Mol. Life Sci. 60, 834-843.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 834-843
-
-
Fluiter, K.1
Housman, D.2
Ten Asbroek, A.L.M.A.3
Baas, F.4
-
6
-
-
0037326836
-
In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides
-
FLUITER, K., TEN ASBROEK, A.L.M.A., DE WISSEL, M.B., JAKOBS, M.E., WISSENBACH, M., OLSSON, H., OLSEN, O., OERUM, H., and BAAS F. (2003b). In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides. Nucleic Acids Res. 31, 953-962.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 953-962
-
-
Fluiter, K.1
Ten Asbroek, A.L.M.A.2
De Wissel, M.B.3
Jakobs, M.E.4
Wissenbach, M.5
Olsson, H.6
Olsen, O.7
Oerum, H.8
Baas, F.9
-
7
-
-
0036532142
-
Tumor genotype specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II
-
FLUITER, K., TEN ASBROEK, A.L.M.A., VAN GROENINGEN, M., NOOIJ, M., AALDERS, M.C.G., and BAAS, F. (2002). Tumor genotype specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II. Cancer Res. 62, 2024-2028.
-
(2002)
Cancer Res.
, vol.62
, pp. 2024-2028
-
-
Fluiter, K.1
Ten Asbroek, A.L.M.A.2
Van Groeningen, M.3
Nooij, M.4
Aalders, M.C.G.5
Baas, F.6
-
8
-
-
0344011088
-
Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA
-
FRIEDEN, M., CHRISTENSEN, S.M., MIKKELSEN, N.D., ROSENBOHM, C., THRUE, C.A., WESTERGAARD, M., HANSEN, H.F., ORUM, H., and KOCH, T. (2003). Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA. Nucleic Acids Res. 31, 6365-6372.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6365-6372
-
-
Frieden, M.1
Christensen, S.M.2
Mikkelsen, N.D.3
Rosenbohm, C.4
Thrue, C.A.5
Westergaard, M.6
Hansen, H.F.7
Orum, H.8
Koch, T.9
-
9
-
-
0031913494
-
Intracellular and extracellular blood magnesium fractions in hemodialysis patients: Is the ionized fraction a measure of magnesium excess?
-
HUIJGEN, H.J., SANDERS, R., VAN OLDEN, R.W., KLOUS, M.G., GAFFAR, F.R., and SANDERS, G.T. (1998). Intracellular and extracellular blood magnesium fractions in hemodialysis patients: Is the ionized fraction a measure of magnesium excess? Clin. Chem. 44, 639-648.
-
(1998)
Clin. Chem.
, vol.44
, pp. 639-648
-
-
Huijgen, H.J.1
Sanders, R.2
Van Olden, R.W.3
Klous, M.G.4
Gaffar, F.R.5
Sanders, G.T.6
-
10
-
-
0034804143
-
RNA cleavage by the 10-23 DNA enzyme
-
JOYCE, G.F. (2001). RNA cleavage by the 10-23 DNA enzyme. Methods Enzymol. 341, 503-517.
-
(2001)
Methods Enzymol.
, vol.341
, pp. 503-517
-
-
Joyce, G.F.1
-
11
-
-
0032473890
-
LNA: Synthesis of the adenine, cytosine, guanine 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation and unprecedented nucleic acid recognition
-
KOSHKIN, A., SINGH, S.K., NIELSEN, P., RAJWANSHI, V.K., KUMAR, R., MELGAARD, M., OLSEN, C.E., and WENGEL, J. (1998). LNA: Synthesis of the adenine, cytosine, guanine 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation and unprecedented nucleic acid recognition. Tetrahedron 54, 3607-3630.
-
(1998)
Tetrahedron
, vol.54
, pp. 3607-3630
-
-
Koshkin, A.1
Singh, S.K.2
Nielsen, P.3
Rajwanshi, V.K.4
Kumar, R.5
Melgaard, M.6
Olsen, C.E.7
Wengel, J.8
-
12
-
-
0036567147
-
Design of antisense oligonucleotides stabilized by locked nucleic acids
-
KURRECK, J., WYSZKO, E., GILLEN, C., and ERDMANN, V. A. (2002). Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res. 30, 1911-1918.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1911-1918
-
-
Kurreck, J.1
Wyszko, E.2
Gillen, C.3
Erdmann, V.A.4
-
13
-
-
0032542364
-
Genetic instabilities in human cancers
-
LENGAUER, C., KINZLER, K.W., and VOGELSTEIN, B. (1998). Genetic instabilities in human cancers. Nature 396, 643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
14
-
-
2942642252
-
Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1
-
MITCHELL, A., DASS, C.R., SUN, L.Q., and KHACHIGIAN, L.M. (2004). Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1. Nucleic Acids Res. 32, 3065-3069.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 3065-3069
-
-
Mitchell, A.1
Dass, C.R.2
Sun, L.Q.3
Khachigian, L.M.4
-
15
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd ed. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).
-
(1989)
Molecular Cloning: A Laboratory Manual
, vol.2
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
16
-
-
0030898510
-
A general-purpose RNA-cleaving DNA enzyme
-
SANTORO, S.W., and JOYCE, G.F. (1997). A general-purpose RNA-cleaving DNA enzyme. Proc. Natl. Acad. Sci. USA 94, 4262-4266.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4262-4266
-
-
Santoro, S.W.1
Joyce, G.F.2
-
17
-
-
2342523304
-
Gaining target access for deoxyribozymes
-
SCHUBERT, S., FURSTE, J.P., WERK, D., GRUNERT, H.P., ZEICHHARDT, H., ERDMANN, V.A., and KURRECK, J. (2004). Gaining target access for deoxyribozymes J. Mol. Biol. 339, 355-363.
-
(2004)
J. Mol. Biol.
, vol.339
, pp. 355-363
-
-
Schubert, S.1
Furste, J.P.2
Werk, D.3
Grunert, H.P.4
Zeichhardt, H.5
Erdmann, V.A.6
Kurreck, J.7
-
18
-
-
0344442416
-
RNA cleaving 10-23 DNAzymes with enhanced stability and activity
-
SCHUBERT, S., GUL, D.C., GRUNERT, H.P., ZEICHHARDT, H., ERDMANN, V.A., and KURRECK, J. (2003). RNA cleaving 10-23 DNAzymes with enhanced stability and activity. Nucleic Acids Res. 31, 5982-5992.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 5982-5992
-
-
Schubert, S.1
Gul, D.C.2
Grunert, H.P.3
Zeichhardt, H.4
Erdmann, V.A.5
Kurreck, J.6
-
19
-
-
0033529188
-
Single-nucleotide polymorphisms can cause different structural folds of mRNA
-
SHEN, L.X., BASILION, J.P., and STANTON, V.P., JR. (1999). Single-nucleotide polymorphisms can cause different structural folds of mRNA. Proc. Natl. Acad. Sci. USA 96, 7871-7876.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7871-7876
-
-
Shen, L.X.1
Basilion, J.P.2
Stanton Jr., V.P.3
-
20
-
-
0034160083
-
Polymorphisms in the large subunit of human RNA polymerase II as target for allele-specific inhibition
-
TEN ASBROEK, A.L.M.A., FLUITER, K., VAN GROENIGEN, M., NOOIJ, M., and BAAS, F. (2000). Polymorphisms in the large subunit of human RNA polymerase II as target for allele-specific inhibition. Nucleic Acids Res. 28, 1133-1138.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1133-1138
-
-
Ten Asbroek, A.L.M.A.1
Fluiter, K.2
Van Groenigen, M.3
Nooij, M.4
Baas, F.5
-
21
-
-
0347768059
-
Genetic variation in mRNA coding sequences of highly conserved genes
-
TEN ASBROEK, A.L.M.A., OLSEN, J., HOUSMAN, D., BAAS, F., and STANTON, V.P., JR. (2001). Genetic variation in mRNA coding sequences of highly conserved genes. Physiol. Genomics 5, 113-118.
-
(2001)
Physiol. Genomics
, vol.5
, pp. 113-118
-
-
Ten Asbroek, A.L.M.A.1
Olsen, J.2
Housman, D.3
Baas, F.4
Stanton Jr., V.P.5
-
22
-
-
0036164420
-
The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides
-
TEN ASBROEK, A.L.M.A., VAN GROENIGEN, M., NOOIJ, M., and BAAS, F. (2002). The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides. Eur. J. Biochem. 269, 583-592.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 583-592
-
-
Ten Asbroek, A.L.M.A.1
Van Groenigen, M.2
Nooij, M.3
Baas, F.4
-
23
-
-
0037145999
-
LNAzymes: Incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage
-
VESTER, B., LUNDBERG, L.B., SORENSEN, M.D., BABU, B.R., DOUTHWAITE, S., and WENGEL, J. (2002). LNAzymes: Incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage. J. Am. Chem. Soc. 124, 13682-13683.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 13682-13683
-
-
Vester, B.1
Lundberg, L.B.2
Sorensen, M.D.3
Babu, B.R.4
Douthwaite, S.5
Wengel, J.6
-
24
-
-
0030962761
-
Allelotype of pediatric rhabdomyosarcoma
-
VISSER, M., SIJMONS, C.C., BRAS, J., ARCECI, R.J., GODFRIED, M., VALENTIJN, L.J., VOÛTE, P.A., and BAAS, F. (1997). Allelotype of pediatric rhabdomyosarcoma. Oncogene 15, 1309-1314.
-
(1997)
Oncogene
, vol.15
, pp. 1309-1314
-
-
Visser, M.1
Sijmons, C.C.2
Bras, J.3
Arceci, R.J.4
Godfried, M.5
Valentijn, L.J.6
Voûte, P.A.7
Baas, F.8
-
25
-
-
0034625010
-
Potent and nontoxic antisense oligonucleotides containing locked nucleic acids
-
WAHLESTEDT, C., SALMI, P., GOOD, L., KELA, J., JOHNSSON, T., HOKFELT, T., BROBERGER, C., PORRECA, F., LAI, J., REN, K., OSSIPOV, M., KOSHKIN, A., JAKOBSEN, N., SKOUV, J., OERUM, H., JACOBSEN, M.H., and WENGEL, J. (2000). Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc. Natl. Acad. Sci. USA 97, 5633-5638.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5633-5638
-
-
Wahlestedt, C.1
Salmi, P.2
Good, L.3
Kela, J.4
Johnsson, T.5
Hokfelt, T.6
Broberger, C.7
Porreca, F.8
Lai, J.9
Ren, K.10
Ossipov, M.11
Koshkin, A.12
Jakobsen, N.13
Skouv, J.14
Oerum, H.15
Jacobsen, M.H.16
Wengel, J.17
|