Intracellular and extracellular blood magnesium fractions in hemodialysis patients; Is the ionized fraction a measure of magnesium excess?

Clinical Chemistry

Volumn 44, Issue 3, 1998, Pages 639-648

  Huijgen, Henk J ^a   Sanders, Renata ^a   Van Olden, Rudolf W ^b   Klous, Marjolein G ^a   Gaffar, Faryal R ^a   Sanders, Gerard T B ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b F1 217 ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION;

ARTICLE; CONTROLLED STUDY; ERYTHROCYTE LEVEL; HEMODIALYSIS; HUMAN; HYPERMAGNESEMIA; MAGNESIUM BLOOD LEVEL; MINERAL BALANCE; MONONUCLEAR CELL;

EID: 0031913494     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/44.3.639     Document Type: Article

References (40)

1. Rouilly M, Rusterholz B, Spichiger UE, Simon W. Neutral ionophore-based selective electrode for assaying the activity of Mg in undiluted blood serum. Clin Chem 1990;36:466-9.
2. van Ingen HE, Huijgen HJ, Kok WTh, Sanders GTB. Analytical evaluation of Kone Microlyte determination of ionized magnesium. Clin Chem 1994;40:52-5.
3. Huijgen HJ, van Ingen HE, Kok WTh, Sanders GTB. Magnesium fractions in serum of healthy individuals and CAPD patients, measured by an ion-selective electrode and Ultrafiltration. Clin Biochem 1996;29:261-6.
4. Swinger R, Antoni DH, Guder WG. Simultaneous determination of magnesium and potassium in lymphocytes, erythrocytes and thrombocytes. J Trace Elem Electrolytes Health Dis 1987;1:89-98.
5. Contigluglia SR, Alfrey AC, Miller N, Butkus D. Total-body magnesium excess in chronic renal failure. Lancet 1972;i:1300-2.
6. Touyz RM, Milne FJ. A method for determining the total magnesium, calcium, sodium and potassium contents of human platelets. Miner Electrolyte Metab 1991;17:173-8.
7. Ng LL, Davies JE, Garrido MC. Intracellular free magnesium in human lymphocytes and the response to lectins. Clin Sci 1991; 80:539-47.
8. Huijgen HJ, van Ingen HE, Sanders R, Gaffar FR, Oosting J, Sanders GTB. Precision of the magnesium determination in mononuclear blood cells and erythrocytes. Clin Biochem 1997;30: 203-8.
9. Raju B, Murphy E, Levy LA, Hall RD, London RE. A fluorescent indicator for measuring cytosolic free magnesium. Am J Physiol 1989;256:C540-8.
10. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-50.
11. 2+ signaling during activation with opsonized particles. FEBS Lett 1990;270: 49-52.
12. 2+ from intracellular stores in rat portal vein myocytes. Br J Pharmacol 1996;118:73-8.
13. Elin RJ. Assessment of magnesium status [Review]. Clin Chem 1987;33:1965-70.
14. Reinhard RA. Magnesium metabolism: a review with special reference to the relationship between intracellular content and serum levels. Arch Intern Med 1988;148:2415-20.
15. Elin RJ. Magnesium: the fifth but forgotten electrolyte [Review]. Am J Clin Pathol 1994;102:616-22.
16. Shafik IM, Dirks JH. Hypo- and hypermagnesaemia. Chap. 14 in: Cameron S, Davidson AM, Grünfeld JP, Kerr D, Ritz E, eds. Oxford textbook of clinical nephrology, Vol. 3. Oxford: Oxford University Press, 1992:1802-21.
17. Gonella M, Giovanni C. Magnesium status in chronically haemodialyzed patients: the role of dialysate magnesium concentration. Magnes Res 1989;2:259-66.
18. Niemela JE, Brent M, Snader, Elin RJ. Determination of ionized magnesium in platelets and correlation with selected variables. Clin Chem 1996;42:744-8.
19. Kisters K, Spieker C, Tepel M, Wenserski F, Zidek W. Plasma, cytosolic and membrane magnesium content in renal insufficiency. Magnes Res 1995;8:167-72.
20. Kaupke CJ, Zhou XJ, Vaziri D. Cytosolic ionized magnesium concentration in end-stage renal disease: effect of hemodialysis. ASAIO J 1993;39:M614-7.
21. Walser M. Magnesium metabolism. Rev Physiol Biochem Exp Pharmacol 1967;59:185-296.
22. Watson WS, Lyon TDB, Hildittch TE. Red cell magnesium as a function of cell age. Metabolism 1980;29:397-9.
23. Elin RJ, Utter A, Tan HK, Corash L. Effect of magnesium deficiency on erythrocyte aging in rats. Am J Pathol 1980;100:765-78.
24. Vormann J, Günther T, Perras B, Rob PM. Magnesium metabolism in erythrocytes of patients with chronic renal failure and after renal transplantation. Eur J Clin Chem Clin Biochem 1994;32:901-4.
25. Ng LL, Garrido MC, Davies JE, Brochwicz-Lewinski MJ, Tan LB. Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics with and without amiloride. J Clin Pharmacol 1992;33:329-32.
26. Willems HL, Kruse J, Geven WB, Vis P, Monnens LAH. Defibrination essential in the assay of ionized magnesium in mononuclear cells. Eur J Clin Chem Clin Biochem 1995;33:103-4.
27. Lemmers J, Willems JL, Vis P, Reddingius RE, Schroder CH, Monnens LAH. Intracellular (free) ionized magnesium in lymphocytes of young CAPD patients [Dutch]. Ned Tijdschr Klin Chem 1995;20:122.
28. Grierson JP, Petroski RE, O'Connell SM, Geller HM. Calcium homeostasis in dissociated embryonic neurons: a flow cytometric study. J Neurophysiol 1992;67:704-14.
29. Yoshimura M, Oshima T, Matsuura H, Watanabe M, Hogashi Y, Ono N, et al. Effect of the transmembrane gradient of magnesium and sodium on the regulation of cytosolic free magnesium concentration in human platelets. Clin Sci 1995;89:293-8.
30. Yoshimura M, Oshima T, Matsuura H, Watanabe M, Hogashi Y, Ono N, et al. Assessment of platelet cytosolic concentration of free magnesium in healthy subjects. J Lab Clin Med 1995;125: 743-7.
31. Syrjälä MT, Tiirikainen M, Jansson SE, Krusius T. Flow cytometric analysis of terminal deoxynucleotidyl transferase, a simplified method. Am J Clin Pathol 1993;99:298-303.
32. Chrzanowska-Nightowlers ZMA, Turnbull DM, Nightowlers RN. A microtiter plate assay for cytochrome c oxidase in permeabilized whole cells. Anal Biochem 1993;214:45-9.
33. Tiirikainen MI. Evaluation of red blood cell lysing solutions for the detection of intracellular antigens by flow cytometry. Cytometry 1995;20:241-8.
34. Grubbs RD, Beltz PA, Koss KL. Practical considerations for using Mag-fura-2 to measure cytosolic free magnesium. Magnes Trace Elem 1991;92:10:142-50.
35. Schoenmakers TJM, Visser GJ, Flik G, Theuvenet APR. CHELATOR. An improved method for computing metal ion concentrations in physiological solutions. BioTechniques 1992;12:870-9.
36. Morelle B, Salmon JM, Vigo J, Viallet P. Are intracellular ionic concentrations accessible using fluorescent probes? The example of Mag-indo-1. Cell Biol Toxicol 1994;10:339-44.
37. Lattanzio FA, Bartschat KD. The effect of pH on rate constant, ion selectivity and thermodynamic properties of fluorescent calcium and magnesium indicators. Biochem Biophys Res Commun 1991; 177:184-91.
38. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;i:307-10.
39. Markell MS, Altura BT, Sarn Y, Delano BG, Ifudu O, Friedman EA, Altura BM. Deficiency of serum ionized magnesium in patients receiving hemodialysis or peritoneal dialysis. ASAIO J 1993;39: M801-4.
40. Sanders R, Draaijer A, Gerritsen GC, Houpt RM, Levine YK. Quantitative pH imaging in cells using confocal fluorescence lifetime imaging microscopy. Anal Biochem 1995;227:302-8.