Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine α-amidating monooxygenase (PAM)

FEBS Letters

Volumn 580, Issue 2, 2006, Pages 521-532

  McIntyre, Neil R ^a   Lowe Jr , Edward W ^a   Chew, Geoffrey H ^a   Owen, Terrence C ^a   Merkler, David J ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Enzyme inhibition; Peptidylglycine amidating enzyme; Thiorphan; Tiopronin

Indexed keywords

ALPHA AMIDATING ENZYME; COPPER; GLYCINE; GLYCINE DERIVATIVE; N ACYLGLYCINE; N BENZOGLYCINE; THIORPHAN; TIOPRONIN; UNCLASSIFIED DRUG;

AMIDATION; ARTICLE; DOSE RESPONSE; DRUG BINDING; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG INHIBITION; HUMAN; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; COPPER; MIXED FUNCTION OXYGENASES; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; OXIDATION-REDUCTION; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; RATS; THIOPRONINE; THIORPHAN;

EID: 30744432397     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.12.058     Document Type: Article

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