Expression of peptidyl-glycine α-amidating mono-oxygenase (PAM) enzymes in morphological abnormalities adjacent to pulmonary tumors

American Journal of Pathology

Volumn 149, Issue 2, 1996, Pages 707-716

  Martínez, Alfredo ^a,c   Treston, Anthony M ^a   Saldise, Laura ^b   Montuenga, Luis M ^b   Linnoila, R Ilona ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF NAVARRA   (Spain)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMIDATING ENZYME; PEPTIDE HORMONE;

ADULT; AGED; ARTICLE; CARCINOMA IN SITU; CELL HYPERPLASIA; ENZYME ANALYSIS; FEMALE; HUMAN; HUMAN TISSUE; LUNG CARCINOGENESIS; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; SQUAMOUS CELL METAPLASIA;

ADULT; AGED; BRONCHI; CARCINOMA; CARCINOMA IN SITU; CARCINOMA, SMALL CELL; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG NEOPLASMS; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES; MULTIENZYME COMPLEXES; PEPTIDES; PRECANCEROUS CONDITIONS; PULMONARY ALVEOLI; TUMOR MARKERS, BIOLOGICAL;

EID: 0030038259     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Parker SL, Tong T, Bolden S, Wingo PA: Cancer Statistics. CA-Cancer J Clin 1996, 65:5-27
2. Mulshine JL, Scott F, Zhou J, Avis I, Vos M, Miller MJ, Szabo E, Martínez A, Treston AM, Cuttitta F, Tockman M: Development of molecular approaches to early lung cancer detection. Semin Rad Oncol 1996, 6:1-5
3. Slaughter DP, Southwick HW, Smejkal W: "Field cancerization" in oral stratified squamous epithelium. Cancer 1953, 6:963-968
4. Sabichi AL, Birrer MJ: The molecular biology of lung cancer: application to early detection and prevention. Oncology 1993, 7:19-26
5. Auerbach O, Stout AP, Hammond C, Garfinkel MA: Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N Engl J Med 1961, 265:253-267
6. Sozzi G, Miozzo M, Pastorino U, Pilotti S, Donghi R, Giarola M, De Gregorio L, Manenti G, Radice P, Minoletti F: Genetic evidence for an independent origin of multiple preneoplastic and neoplastic lesions. Cancer Res 1995, 55:135-140
7. Saccomanno G, Archer VE, Auerbach O: Development of carcinoma of the lung as reflected in exfoliated cells. Cancer 1974, 33:256-270
8. Lee JS, Hong WK: Biology of preneoplastic lesions. Lung Cancer. Edited by JA Roth, JD Cox, WK Hong. Boston, Blackwell Scientific Publications, 1993, pp 34-56
9. Tockman MS, Gupta PK, Myers JD, Frost JK, Baylin SB, Gold EB, Chase AM, Wilkinson PH, Mulshine JL: Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: a new approach to early lung cancer detection. J Clin Oncol 1988, 6:1685-1693
10. Tockman MS, Erozan YS, Gupta PK, Piantadosi S, Mulshine JL, Ruckdeschel JC: The early detection of second primary lung cancers by sputum immunostaining. Chest 1994, 106:385S-390S
11. Jensen SM, Jones JE, Pass H, Steinberg SM, Linnoila RI: Clara cell 10 kDa protein mRNA in normal and atypical regions of human respiratory epithelium, Int J Cancer 1994, 58:629-637
12. Sozzi G, Miozzo M, Tagliabue E, Calderone C, Lombardi L, Pilotti S, Pastorino U, Pierotti MA, Della Porta G: Cytogenetic abnormalities and overexpression of receptors for growth factors in normal bronchial epithelium and tumor samples of lung cancer patients. Cancer Res 1991, 51:400-404
13. Scott F, Cuttitta F, Treston AM, Avis I, Gupta P, Ruckdeschel J, Kelly K, Piantadosi S, Tockman M, Mulshine J: Prospective trial evaluating immunocytochemical-based sputum techniques for early lung cancer detection: assays for promotion factors in the bronchial lavage J Cell Biochem Suppl 1993, 17F:175-183
14. Treston AM, Scott FM, Vos M, Iwai N, Mains RE, Eipper BA, Cuttitta F, Mulshine JL: Biochemical characterization of peptide α-amidation enzyme activities of human neuroendocrine lung cancer cell lines. Cell Growth Differ 1993, 4:911-920
15. Saldise L, Martínez A, Montuenga LM, Treston AM, Springall DR, Polak JM, Vázquez JJ: Distribution of peptidyl-glycine α-amidating monooxygenase (PAM) enzymes in normal human lung and in lung epithelial tumors. J Histochem Cytochem 1996, 44:3-12
16. Merkler DJ: C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb Technol 1994, 16:450-456
17. Eipper BA, Stoffers DS, Mains RE: The biosynthesis of neuropeptides: peptide α-amidation. Annu Rev Neurosci 1992, 15:57-85
18. Mulshine JL, Treston AM, Brown PH. Mirrer MJ, Shaw GL: Initiators and promoters of lung cancer. Chest 1993, 103:4S-11S
19. Treston AM, Mulshine JL, Cuttitta F: Control of tumor cell biology through regulation of peptide hormone processing. J Natl Cancer Inst Monogr 1992, 13:169-175
20. Vos MD, Scott FM, Iwai N, Treston AM: Expression in human lung cancer cell lines of genes of prohormone processing and the neuroendocrine phenotype. J Cell Biochem 1996 (in press)
21. Colby TV, Koss MN, Travis WD: Atlas of Tumor Pathology. Tumors of the Respiratory Tract. Edited by J Rosai, LH Sobin. Washington, DC, Armed Forces Institute of Pathology, 1994
22. Hsu SM, Raine L, Fanger H: Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison betwen ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981, 29:577-580
23. Martínez A, Montuenga LM, Springall DR, Treston A, Cuttitta F, Polak JM: Immunocytochemical localization of peptidylglycine α-amidating monooxygenase enzymes (PAM) in human endocrine pancreas. J Histochem Cytochem 1993, 41:375-380
24. Tateishi K, Arakawa F, Misumi Y, Treston AM, Vos M, Matsuoka Y: Isolation and functional expression of human pancreatic peptidylglycine α-amidating monooxygenase. Biochem Biophys Res Commun 1994, 205: 282-290
25. Shu SY, Ju G, Fan LZ: The glucose-oxidase DAB-nickel method in peroxidase histochemistry of the nervous system. Neurosci Lett 1988, 85:169-171
26. Gibson SJ, Polak JM: Principles and applications of complementary RNA probes. In Situ Hybridization: Principles and Practice. Edited by JM Polak, JO'D McGee. New York, Oxford University Press, 1990, pp 81-94
27. Glauder J, Ragg H, Rauch J, Engels JW: Human peptidyl-glycine α-amidating monooxygenase: c-DNA, cloning, and functional expression of a truncated form in COS cells. Biochem Biophys Res Commun 1990, 169:551-558
28. Nasiell M: The general appearance of the bronchial epithelium in bronchial carcinoma: a histopathological study with some cytological viewpoints. Acta Cytol 1963, 7:97-106
29. Nettesheim P, Szakal MS: Morphogenesis of alveolar bronchiolization. Lab Invest 1972, 26:210-219
30. Mori M, Chiba R, Takahashi T: Atypical adenomatous hyperplasia of the lung and its differentiation from adenocarcinoma: characterization of atypical cells by morphometry and multivariate cluster analysis. Cancer 1993, 72:2331-2340
31. Solomon M, Greenberg D, Spjut H: Morphology of bronchial epithelium adjacent to adenocarcinoma of the lung. Mod Pathol 1990, 3:684-687
32. Broers JLV, Jensen SM, Travis WD, Pass H, Whitsett JA, Singh G, Katyal SL, Gazdar AF, Minna JD, Linnoila RI: Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization. Lab Invest 1992, 66:337-346
33. Linnoila RI, Mulshine JL, Steinberg SM, Gazdar AF: Expression of surfactant-associated protein in non-small-cell lung cancer: a discriminant between biologic subsets. J Natl Cancer Inst Monogr 1992, 13:61-66
34. Ulich TR, Yi ES, Longmuir K, Yin S, Biltz R, Morris CF, Housley RM, Pierce GF: Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo. J Clin Invest 1994, 93:1298-1306
35. Iwai N, Avis I, Scott F, Quinn K, Cuttitta F, Mulshine JL, Treston A: Novel tumor cell growth inhibitors acting via autocrine loops which are dependent on peptidyl α-amidating enzyme. Proc Am Assoc Cancer Res 1993, 34:266
36. Martínez A, Vos M, Treston A: Antisense expression of peptide amidating enzyme RNA reduces growth in tumor cells. 77th Annual Meeting Endocrine Society 1995, p 277
37. Rao SK, Fraire AE: Alveolar cell hyperplasia in association with adenocarcinoma of lung Mod Pathol 1995, 8:165-169
38. Carey FA, Wallace WA, Fergusson RJ, Kerr KM, Lamb D: Alveolar atypical hyperplasia in association with primary pulmonary adenocarcinoma: a clinicopathological study of 10 cases. Thorax 1992, 47:1041-1043
39. Belinsky SA, Devereux TR, Foley JF, Maronpot RR, Anderson MW: Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse. Cancer Res 1992, 52:3164-3173
40. Kerr KM, Carey FA, King G, Lamb D: Atypical alveolar hyperplasia: relationship with pulmonary adenocarcinoma, p53, and c-erbB-2 expression. J Pathol 1994, 174:249-256
41. Williams AO, Flanders KC, Saffiotti U: Immunohistochemical localization of transforming growth factor-β 1 in rats with experimental silicosis, alveolar type II hyperplasia, and lung cancer. Am J Pathol 1993, 142: 1831-1840
42. Keenan KP: Cell injury and repair of the tracheobronchial epithelium. Lung Carcinomas Edited by EM McDowell. New York, Churchill Livingstone, 1987, pp 74-93
43. Plopper CG, Dungworth DL: Structure, function, cell injury, and cell renewal of bronchiolar-alveolar epithelium. Lung Carcinomas Edited by EM McDowell. New York, Churchill Livingstone, 1987, pp 94-128