Expression of adrenomedullin and peptide amidation activity in human prostate cancer and in human prostate cancer cell lines

Cancer Research

Volumn 61, Issue 3, 2001, Pages 1196-1206

  Rocchi, Palma ^a   Boudouresque, Françoise ^a   Zamora, Alfredo J ^b   Muracciole, Xavier ^a,c   Lechevallier, Eric ^d   Martin, Pierre Marie ^a   Ouafik, L’Houcine ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^b CNRS   (France)

^c TIMONE HOSPITAL   (France)

^d Child and Adolescent Psychopathology Unit Salvator Hospital Public Assistance Marseille Hospitals University Aix Marseille II   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; ALPHA AMIDATING ENZYME; ANDROGEN; GROWTH FACTOR; MESSENGER RNA; NEURON SPECIFIC ENOLASE; PEPTIDE;

AMIDATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CANCER GROWTH; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCATION; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; MALE; MOUSE; NEUROSECRETORY CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROGNOSIS; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATE HYPERTROPHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; ADRENOMEDULLIN; ANIMALS; CELL DIVISION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, NUDE; MIXED FUNCTION OXYGENASES; MULTIENZYME COMPLEXES; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS, HORMONE-DEPENDENT; PEPTIDES; PHOSPHOPYRUVATE HYDRATASE; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0035117130     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Cancer statistics
2. Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: A stem cell model
3. Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate: Simultaneous demonstration of cell-specific epithelial markers
4. The proliferative function of basal cells in the normal and hyperplastic human prostate
5. Neuroendocrine differentiation in human prostatic carcinoma
6. Neuroendocrine differentiation in prostatic malignancy
7. Bombesin stimulates growth of human prostatic cancer cells in vitro
8. Parathyroid hormone-related protein: A potential autocrine growth regulator in human prostate cancer cell lines
9. 2+transients
10. Peptide-hormone- and serotonin-immunoreactive tumor cells in carcinoma of the prostate
11. Neuroendocrine differentiation in carcinoma of the prostate
12. The course of neuroendocrine differentiation in prostatic carcinomas: An immunohistochemical study testing chromogranin A as an "endocrine marker"
13. Neuro-endocrine cells - A new prognostic parameter in prostate cancer
14. Small cell carcinoma of the prostate: A clinicopathologic study of 20 cases
15. Androgen receptor status in endocrine-paracrine cell types of the normal, hyperplastic, and neoplastic human prostate
16. Decrement of blood flow precedes the involution of the ventral prostate in the rat after castration
17. Rapid reduction in blood flow to the rat ventral prostate gland after castration: Preliminary evidence that androgens influence prostate size by regulating blood flow to the prostate gland and prostatic endothelial cell survival
18. Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation
19. Estrogen regulation of peptidylglycine α-amidating monooxygenase expression in anterior pituitary gland
20. The biosynthesis of neuropeptides: Peptide α-amidation
21. Human peptidylglycine α-amidating monooxygenase: cDNA, cloning, and functional expression of a truncated form in COS cells
22. Localization of the gene encoding peptidylglycine α-amidating monooxygenase (PAM) to human chromosome 5q14-5q21
23. The multifunctional peptidylglycine α-amidating monooxygenase gene: Exon/intron organization of catalytic, processing, and routing domains
24. Alternative splicing and endoproteolytic processing generate tissue-specific forms of pituitary peptidylglycine α-amidating monooxygcnase (PAM)
25. Adrenomedullin: A novel hypotensive peptide isolated from human pheochromocytoma
26. Adrenomedullin, a multifunctional regulatory peptide
27. Adrenomedullin terra incognita
28. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells
29. PCR display identifies tamoxifen induction of the novel angiogenic factor adrenomedullin by a non-estrogenic mechanism in the human endometrium
30. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma
31. Adrenomedullin expression in human tumor cell lines: Its potential role as an autocrine growth factor
32. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
33. Developmental regulation of peptidylglycine α-amidating monooxygenase (PAM) in rat heart atrium and ventricle: Tissue-specific changes in distribution of PAM activity, mRNA levels, and protein forms
34. Cloning and characterization of cDNA encoding a precursor for adrenomedullin
35. The 108-kDA peptidylglycine α-amidating monooxygenase precursor contains two separable enzymatic activities involved in peptide amidation
36. A novel method for real-time quantitative RT-PCR
37. Real-time quantitative PCR
38. Thyroid hormone regulation of peptidylglycine α-amidating monooxygenase expression in anterior pituitary gland
39. Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay
40. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of radiosensitivity
41. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide
42. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells
43. The neuroendocrine cell population of the human prostate gland
44. Neuroendocrine cells in the prostate of the rat, guinea pig, cat, and dog
45. Androgen-independent growth is induced by neuropeptides in human prostate cancer cell lines
46. Prostatic cell lineage markers: Emergence of Bcl2+ cells of human prostate cancer xenograft LuCaP 23 following castration
47. Argyrophilic carcinoma of the male breast: A neuroendocrine tumor containing predominantly chromogranin B (secretogranin I)
48. Mucinous carcinoma of the breast: A clinicopathologic, histochemical, and immunocytochemical study with special reference to neuroendocrine differentiation
49. Argyrophilia and granin (chromogranird secretogranin) expression in female breast carcinomas: Their relationship to survival and other disease parameters
50. A porcine gut polypeptide identical to the pancreatic hormone PP (pancreatic polypeptide)
51. Circulating pancreastutin is a marker for the enterochromaffin-like cells of the rat stomach
52. Peptide α-amidation activity in human plasma: Relationship to gastrin processing
53. Hypergastrinemia and gastric enterochromaffin-like cells
54. Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in human and rat prostate
55. Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: A possible promotion mechanism of carcinogenesis
56. Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells
57. Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
58. The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
59. Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations
60. Partial characterization of a thyroid-stimulating hormone-like peptide in neuroendocrine cells of the human prostate gland
61. Relation of endocrine-paracrine cells to cell proliferation in normal, hyperplastic, and neoplastic human prostate