Engineering cyclic tetrapeptides containing chimeric amino acids as preferred reverse-turn scaffolds

Journal of Medicinal Chemistry

Volumn 49, Issue 1, 2006, Pages 111-124

  Che, Ye ^a,b   Marshall, Garland R ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMINO ACID; AZAPIPECOLIC ACID; AZAPROLINE; CYCLO(DEXTRO PROLYLPROLYLPROLYLPROLINE); ISONIPECOTIC ACID; NIPECOTIC ACID; PIPECOLIC ACID; PROLINE DERIVATIVE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CHIRALITY; CONFORMATIONAL TRANSITION; CYCLIZATION; DENSITY FUNCTIONAL THEORY; DIPOLE; EVALUATION; HIGH TEMPERATURE; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN MOTIF; SIMULATION; STRUCTURE ANALYSIS;

AMINO ACIDS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

EID: 30444460118     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0507072     Document Type: Article

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