-
1
-
-
0031725620
-
Thymine Metabolism and Thymineless Death in Prokaryotes and Eukaryotes
-
Ahmad, S. I.; Kirk, S. H. and Eisenstark, A. (1998) Thymine Metabolism and Thymineless Death in Prokaryotes and Eukaryotes. Annu. Rev. Microbiol. 52, 591-625.
-
(1998)
Annu. Rev. Microbiol.
, vol.52
, pp. 591-625
-
-
Ahmad, S.I.1
Kirk, S.H.2
Eisenstark, A.3
-
2
-
-
0021683001
-
Isolation of Functional cDNA Clones for Human Thymidylate Synthase
-
Ayusawa, D.; Takeishi, K.; Kaneda, S.; Shimizu, K.; Koyama, H. and Seno, T. (1984) Isolation of Functional cDNA Clones for Human Thymidylate Synthase. J. Biol. Chem. 259, 14361-14364.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 14361-14364
-
-
Ayusawa, D.1
Takeishi, K.2
Kaneda, S.3
Shimizu, K.4
Koyama, H.5
Seno, T.6
-
3
-
-
0027081148
-
A Naturally Occurring Tyrosine to Histidine Replacement at Residue 33 of Human Thymidylate Synthase Confers Resistance to 5-fluoro-2′-deoxyuridine in Mammalian and Bacterial Cells
-
Barbour, K. W.; Hoganson, D. K.; Berger, S. H. and Berger, F. G. (1992) A Naturally Occurring Tyrosine to Histidine Replacement at Residue 33 of Human Thymidylate Synthase Confers Resistance to 5-fluoro-2′-deoxyuridine in Mammalian and Bacterial Cells. Mol. Pharmacol. 42, 242-248.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 242-248
-
-
Barbour, K.W.1
Hoganson, D.K.2
Berger, S.H.3
Berger, F.G.4
-
4
-
-
0022344622
-
Thymidylate Synthase Overproduction and Gene Amplification in Fluorodeoxyuridine-resistant Human Cells
-
Berger, S. H.; Jenh, C. H.; Johnson, L. F. and Berger, F. G. (1985) Thymidylate Synthase Overproduction and Gene Amplification in Fluorodeoxyuridine-resistant Human Cells. Mol. Pharmacol. 28, 461-467.
-
(1985)
Mol. Pharmacol.
, vol.28
, pp. 461-467
-
-
Berger, S.H.1
Jenh, C.H.2
Johnson, L.F.3
Berger, F.G.4
-
5
-
-
0037386688
-
Is the Measurement of Thymidylate Synthase to Determine Suitability for Treatment with 5-fluoropyrimidines Ready for Prime Time?
-
Bertino, J. R. and Banerjee, D. (2003) Is the Measurement of Thymidylate Synthase to Determine Suitability for Treatment with 5-fluoropyrimidines Ready for Prime Time? Clin. Cancer Res. 9, 1235-1239.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1235-1239
-
-
Bertino, J.R.1
Banerjee, D.2
-
6
-
-
0025990937
-
Autoregulation of Human Thymidylate Synthase Messenger RNA Translation by Thymidylate Synthase
-
Chu, E.; Koeller, D. M.; Casey, J. L.; Drake, J. C.; Chabner, B. A.; Elwood, P. C.; Zinn, S. and Allegra, C. J. (1991) Autoregulation of Human Thymidylate Synthase Messenger RNA Translation by Thymidylate Synthase. Proc. Natl. Acad. Sci. USA 88, 8977-8981.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8977-8981
-
-
Chu, E.1
Koeller, D.M.2
Casey, J.L.3
Drake, J.C.4
Chabner, B.A.5
Elwood, P.C.6
Zinn, S.7
Allegra, C.J.8
-
7
-
-
0027531524
-
Identification of an RNA Binding Site for Human Thymidylate Synthase
-
Chu, E.; Voeller, D.; Koeller, D. M.; Drake, J. C.; Takimoto, C. H.; Maley, G. F.; Maley, F. and Allegra, C. J. (1993) Identification of an RNA Binding Site for Human Thymidylate Synthase. Proc. Natl. Acad. Sci. USA 90, 517-521.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 517-521
-
-
Chu, E.1
Voeller, D.2
Koeller, D.M.3
Drake, J.C.4
Takimoto, C.H.5
Maley, G.F.6
Maley, F.7
Allegra, C.J.8
-
8
-
-
0041825123
-
Thymidylate Synthase Inhibitors as Anticancer Agents: From Bench to Bedside
-
Chu, E.; Callender, M. A.; Farrell, M. P. and Schmitz, J. C. (2003) Thymidylate Synthase Inhibitors as Anticancer Agents: From Bench to Bedside. Cancer Chemother. Pharmacol. 52, 80-89.
-
(2003)
Cancer Chemother. Pharmacol.
, vol.52
, pp. 80-89
-
-
Chu, E.1
Callender, M.A.2
Farrell, M.P.3
Schmitz, J.C.4
-
9
-
-
0023111335
-
Thymidylate Synthase Gene Amplification in a Colon Tumor Resistant to Fluoropyrimidine Chemotherapy
-
Clark, J. L.; Berger, S. H.; Mittelman, A. and Berger, F. G. (1987) Thymidylate Synthase Gene Amplification in a Colon Tumor Resistant to Fluoropyrimidine Chemotherapy. Cancer Treat. Rep. 71, 261-265.
-
(1987)
Cancer Treat. Rep.
, vol.71
, pp. 261-265
-
-
Clark, J.L.1
Berger, S.H.2
Mittelman, A.3
Berger, F.G.4
-
10
-
-
0037990003
-
Methylenetetrahydrofolate Reductase Polymorphism in Advanced Colorectal Cancer: A Novel Genomic Predictor of Clinical Response to Fluoropyrimidine-based Chemotherapy
-
Cohen, V.; Panet-Raymond, V.; Sabbaghian, N.; Morin, I.; Batist, G. and Rozen, R. (2003) Methylenetetrahydrofolate Reductase Polymorphism in Advanced Colorectal Cancer: A Novel Genomic Predictor of Clinical Response to Fluoropyrimidine-based Chemotherapy. Clin. Cancer Res. 9, 1611-1615.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1611-1615
-
-
Cohen, V.1
Panet-Raymond, V.2
Sabbaghian, N.3
Morin, I.4
Batist, G.5
Rozen, R.6
-
11
-
-
0029052988
-
Thymidylate Synthase Gene Amplification in Human Colon Cancer Cell Lines Resistant to 5-fluorouracil
-
Copur, S.; Aiba, K.; Drake, J. C.; Allegra, C. J. and Chu, E. (1995) Thymidylate Synthase Gene Amplification in Human Colon Cancer Cell Lines Resistant to 5-fluorouracil. Biochem. Pharmacol. 49, 1419-1426.
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 1419-1426
-
-
Copur, S.1
Aiba, K.2
Drake, J.C.3
Allegra, C.J.4
Chu, E.5
-
12
-
-
0141426676
-
The Influence of Cyclin D1 (CCND1) 870A>G Polymorphism and CCND1-thymidylate Synthase (TS) Gene-gene Interaction on the Outcome of Childhood Acute Lymphoblastic Leukaemia
-
Costea, I.; Moghrabi, A. and Krajinovic, M. (2003) The Influence of Cyclin D1 (CCND1) 870A>G Polymorphism and CCND1-thymidylate Synthase (TS) Gene-gene Interaction on the Outcome of Childhood Acute Lymphoblastic Leukaemia. Pharmacogenetics 13, 577-580.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 577-580
-
-
Costea, I.1
Moghrabi, A.2
Krajinovic, M.3
-
13
-
-
0017716458
-
Thymidylate Synthetase - A Target Enzyme in Cancer Chemotherapy
-
Danenberg, P. V. (1977) Thymidylate Synthetase - A Target Enzyme in Cancer Chemotherapy. Biochim. Biophys. Acta 473, 73-92.
-
(1977)
Biochim. Biophys. Acta
, vol.473
, pp. 73-92
-
-
Danenberg, P.V.1
-
15
-
-
0027214923
-
Variation in Human Thymidylate Synthase is Associated with Resistance to 5-fluoro-2′-deoxyuridine
-
Davis, S. T. and Berger, S. H. (1993) Variation in Human Thymidylate Synthase is Associated with Resistance to 5-fluoro-2′-deoxyuridine. Mol. Pharmacol. 43, 702-708.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 702-708
-
-
Davis, S.T.1
Berger, S.H.2
-
16
-
-
0023007963
-
Structure of the Gene for Mouse Thymidylate Synthase. Locations of Introns and Multiple Transcriptional Start Sites
-
Deng, T. L.; Li, D. W.; Jenh, C. H. and Johnson, L. F. (1986) Structure of the Gene for Mouse Thymidylate Synthase. Locations of Introns and Multiple Transcriptional Start Sites. J. Biol. Chem. 261, 16000-16005.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 16000-16005
-
-
Deng, T.L.1
Li, D.W.2
Jenh, C.H.3
Johnson, L.F.4
-
17
-
-
0036939857
-
Evaluation of Thymidylate Synthase Protein Expression by Western Blotting and Immunohistochemistry on Human Colon Carcinoma Xenografts in Nude Mice
-
Derenzini, M.; Montanaro, L.; Chilla, A.; Tosti, E.; Ceccarelli, C.; Dall'Olio, F.; Ofner, D. and Trere, D. (2002) Evaluation of Thymidylate Synthase Protein Expression by Western Blotting and Immunohistochemistry on Human Colon Carcinoma Xenografts in Nude Mice. J. Histochem. Cytochem. 50, 1633-1640.
-
(2002)
J. Histochem. Cytochem.
, vol.50
, pp. 1633-1640
-
-
Derenzini, M.1
Montanaro, L.2
Chilla, A.3
Tosti, E.4
Ceccarelli, C.5
Dall'Olio, F.6
Ofner, D.7
Trere, D.8
-
18
-
-
0037317435
-
Prognosis After Rectal Cancer in Blacks and Whites Participating in Adjuvant Therapy Randomized Trials
-
Dignam, J. J.; Ye, Y.; Colangelo, L.; Smith, R.; Mamounas, E. P.; Wieand, H. S. and Wolmark, N. (2003) Prognosis After Rectal Cancer in Blacks and Whites Participating in Adjuvant Therapy Randomized Trials. J. Clin. Oncol. 21, 413-420.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 413-420
-
-
Dignam, J.J.1
Ye, Y.2
Colangelo, L.3
Smith, R.4
Mamounas, E.P.5
Wieand, H.S.6
Wolmark, N.7
-
19
-
-
0037096901
-
Prognostic Value of Tumoral Thymidylate Synthase and p53 in Metastatic Colorectal Cancer Patients Receiving Fluorouracil-Based Chemotherapy: Phenotypic and Genotypic Analyses
-
Etienne, M. C.; Chazal, M.; Laurent-Puig, P.; Magne, N.; Rosty, C.; Formento, J. L.; Francoual, M.; Formento, P.; Renee, N.; Chamorey, E.; Bourgeon, A.; Seitz, J. F.; Delpero, J. R.; Letoublon, C.; Pezet, D. and Milano, G. (2002) Prognostic Value of Tumoral Thymidylate Synthase and p53 in Metastatic Colorectal Cancer Patients Receiving Fluorouracil-Based Chemotherapy: Phenotypic and Genotypic Analyses. J. Clin. Oncol. 20, 2832-2843.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2832-2843
-
-
Etienne, M.C.1
Chazal, M.2
Laurent-Puig, P.3
Magne, N.4
Rosty, C.5
Formento, J.L.6
Francoual, M.7
Formento, P.8
Renee, N.9
Chamorey, E.10
Bourgeon, A.11
Seitz, J.F.12
Delpero, J.R.13
Letoublon, C.14
Pezet, D.15
Milano, G.16
-
20
-
-
33745464490
-
Fluorinated Pyrimidines, A New Class of Tumour-inhibitory Ccompounds
-
Heidelberger, C.; Chaudhuri, N. K.; Dannenberg, P.; Mooren, D.; Griesbach, L.; Duschinsky, R.; Schnitzer, R. J.; Pleven, E. and Scheiner, T. (1957) Fluorinated Pyrimidines, A New Class of Tumour-inhibitory Ccompounds. Nature 179, 663-666.
-
(1957)
Nature
, vol.179
, pp. 663-666
-
-
Heidelberger, C.1
Chaudhuri, N.K.2
Dannenberg, P.3
Mooren, D.4
Griesbach, L.5
Duschinsky, R.6
Schnitzer, R.J.7
Pleven, E.8
Scheiner, T.9
-
21
-
-
0346037290
-
Differential Alternative Splicing Expressions of Thymidylate Synthase Isoforms
-
Hisatomi, H.; Tanemura, H.; Iizuka, T.; Katsumata, K.; Nagao, K.; Sumida, H.; Udagawa, H. and Hikiji, K. (2003) Differential Alternative Splicing Expressions of Thymidylate Synthase Isoforms. Cancer Lett. 193, 127-131.
-
(2003)
Cancer Lett.
, vol.193
, pp. 127-131
-
-
Hisatomi, H.1
Tanemura, H.2
Iizuka, T.3
Katsumata, K.4
Nagao, K.5
Sumida, H.6
Udagawa, H.7
Hikiji, K.8
-
22
-
-
0037946769
-
Associations Between Polymorphisms in the Thymidylate Synthase and Serine Hydroxymethyltransferase Genes and Susceptibility to Malignant Lymphoma
-
Hishida, A.; Matsuo, K.; Hamajima, N.; Ito, H.; Ogura, M.; Kagami, Y.; Taji, H.; Morishima, Y.; Emi, N. and Tajima, K. (2003) Associations Between Polymorphisms in the Thymidylate Synthase and Serine Hydroxymethyltransferase Genes and Susceptibility to Malignant Lymphoma. Haematologica 88, 159-166.
-
(2003)
Haematologica
, vol.88
, pp. 159-166
-
-
Hishida, A.1
Matsuo, K.2
Hamajima, N.3
Ito, H.4
Ogura, M.5
Kagami, Y.6
Taji, H.7
Morishima, Y.8
Emi, N.9
Tajima, K.10
-
23
-
-
0021802395
-
Assignment of Human Gene Encoding Thymidylate Synthase to Chromosome 18 Using Interspecific Cell Hybrids Between Thymidylate Synthase-negative Mouse Mutant Cells and Human Diploid Fibroblasts
-
Hori, T.; Ayusawa, D.; Shimizu, K.; Koyama, H. and Seno, T. (1985) Assignment of Human Gene Encoding Thymidylate Synthase to Chromosome 18 Using Interspecific Cell Hybrids Between Thymidylate Synthase-negative Mouse Mutant Cells and Human Diploid Fibroblasts. Somat. Cell Mol. Genet. 11, 277-283.
-
(1985)
Somat. Cell Mol. Genet.
, vol.11
, pp. 277-283
-
-
Hori, T.1
Ayusawa, D.2
Shimizu, K.3
Koyama, H.4
Seno, T.5
-
24
-
-
0025083351
-
Regional Assignment of the Human Thymidylate Synthase (TS) Gene to Chromosome Band 18p11.32 by Nonisotopic In Situ Hybridization
-
Hori, T.; Takahashi, E.; Ayusawa, D.; Takeishi, K.; Kaneda, S. and Seno, T. (1990) Regional Assignment of the Human Thymidylate Synthase (TS) Gene to Chromosome Band 18p11.32 by Nonisotopic In Situ Hybridization. Hum. Genet. 85, 576-580.
-
(1990)
Hum. Genet.
, vol.85
, pp. 576-580
-
-
Hori, T.1
Takahashi, E.2
Ayusawa, D.3
Takeishi, K.4
Kaneda, S.5
Seno, T.6
-
25
-
-
0027729193
-
Characterization of Regulatory Sequences and Nuclear Factors that Function in Cooperation with the Promoter of the Human Thymidylate Synthase Gene
-
Horie, N.; Chimoto, M.; Nozawa, R. and Takeishi, K. (1993) Characterization of Regulatory Sequences and Nuclear Factors that Function in Cooperation with the Promoter of the Human Thymidylate Synthase Gene. Biochim. Biophys. Acta 1216, 409-416.
-
(1993)
Biochim. Biophys. Acta
, vol.1216
, pp. 409-416
-
-
Horie, N.1
Chimoto, M.2
Nozawa, R.3
Takeishi, K.4
-
26
-
-
0029122937
-
Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5′-terminal Regulatory Region of the Human Gene for Thymidylate Synthase
-
Horie, N.; Aiba, H.; Oguro, K.; Hojo, H. and Takeishi, K. (1995) Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5′-terminal Regulatory Region of the Human Gene for Thymidylate Synthase. Cell Struct. Funct. 20, 191-197.
-
(1995)
Cell Struct. Funct.
, vol.20
, pp. 191-197
-
-
Horie, N.1
Aiba, H.2
Oguro, K.3
Hojo, H.4
Takeishi, K.5
-
27
-
-
0030750738
-
Identification of Functional Elements in the Promoter Region of the Human Gene for Thymidylate Synthase and Nuclear Factors that Regulate the Expression of the Gene
-
Horie, N. and Takeishi, K. (1997) Identification of Functional Elements in the Promoter Region of the Human Gene for Thymidylate Synthase and Nuclear Factors that Regulate the Expression of the Gene. J. Biol. Chem. 272, 18375-18381.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18375-18381
-
-
Horie, N.1
Takeishi, K.2
-
28
-
-
0031733821
-
Cloning and Characterization of the Promoter Region of Monkey Thymidylate Synthase Gene
-
Horie, N.; Wakabayashi, M.; Katai, H. and Takeishi, K. (1998) Cloning and Characterization of the Promoter Region of Monkey Thymidylate Synthase Gene. Biol. Pharm. Bull. 21, 1020-1023.
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 1020-1023
-
-
Horie, N.1
Wakabayashi, M.2
Katai, H.3
Takeishi, K.4
-
29
-
-
0035207084
-
Characterization of Nuclear Factors that Bind to the Human Thymidylate Synthase Gene in HL-60 Cells Differentiated by All-trans Retinoic Acid Treatment
-
Horie, N.; Komada, Y.; Ueta, Y.; Suzuki, T.; Nozawa, R. and Takeishi, K. (2001) Characterization of Nuclear Factors that Bind to the Human Thymidylate Synthase Gene in HL-60 Cells Differentiated by All-trans Retinoic Acid Treatment. Biol. Pharm. Bull. 24, 1351-1355.
-
(2001)
Biol. Pharm. Bull.
, vol.24
, pp. 1351-1355
-
-
Horie, N.1
Komada, Y.2
Ueta, Y.3
Suzuki, T.4
Nozawa, R.5
Takeishi, K.6
-
30
-
-
0026560328
-
Quantitation of Thymidylate Synthase, Dihydrofolate Reductase, and DT- diaphorase Gene Expression in Human Tumors Using the Polymerase Chain Reaction
-
Horikoshi, T.; Danenberg, K. D.; Stadlbauer, T. H.; Volkenandt, M.; Shea, L. C.; Aigner, K.; Gustavsson, B.; Leichman, L.; Frosing, R.; Ray, M.; Gibson, N. W.; Spears, C. P. and Danenberg, P. V. (1992) Quantitation of Thymidylate Synthase, Dihydrofolate Reductase, and DT- diaphorase Gene Expression in Human Tumors Using the Polymerase Chain Reaction. Cancer Res. 52, 108-116.
-
(1992)
Cancer Res.
, vol.52
, pp. 108-116
-
-
Horikoshi, T.1
Danenberg, K.D.2
Stadlbauer, T.H.3
Volkenandt, M.4
Shea, L.C.5
Aigner, K.6
Gustavsson, B.7
Leichman, L.8
Frosing, R.9
Ray, M.10
Gibson, N.W.11
Spears, C.P.12
Danenberg, P.V.13
-
31
-
-
0035860142
-
A Polymorphism in the Enhancer Region of the Thymidylate Synthase Promoter Influences the Survival of Colorectal Cancer Patients Treated with 5-fluorouracil
-
Iacopetta, B.; Grieu, F.; Joseph, D. and Elsaleh, H. (2001) A Polymorphism in the Enhancer Region of the Thymidylate Synthase Promoter Influences the Survival of Colorectal Cancer Patients Treated with 5-fluorouracil. Br. J. Cancer 85, 827-830.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 827-830
-
-
Iacopetta, B.1
Grieu, F.2
Joseph, D.3
Elsaleh, H.4
-
32
-
-
0036765664
-
Association of Thymidylate Synthase Gene Polymorphism with its mRNA and Protein Expression and With Prognosis in Gastric Cancer
-
Ishida, Y.; Kawakami, K.; Tanaka, Y.; Kanehira, E.; Omura, K. and Watanabe, G. (2002) Association of Thymidylate Synthase Gene Polymorphism with its mRNA and Protein Expression and With Prognosis in Gastric Cancer. Anticancer Res. 22, 2805-2809.
-
(2002)
Anticancer Res.
, vol.22
, pp. 2805-2809
-
-
Ishida, Y.1
Kawakami, K.2
Tanaka, Y.3
Kanehira, E.4
Omura, K.5
Watanabe, G.6
-
33
-
-
0026335113
-
Production and Characterization of Monoclonal Antibodies that Localize Human Thymidylate Synthase in the Cytoplasm of Human Cells and Tissue
-
Johnston, P. G.; Liang, C. M.; Henry, S.; Chabner, B. A. and Allegra, C. J. (1991) Production and Characterization of Monoclonal Antibodies that Localize Human Thymidylate Synthase in the Cytoplasm of Human Cells and Tissue. Cancer Res. 51, 6668-6676.
-
(1991)
Cancer Res.
, vol.51
, pp. 6668-6676
-
-
Johnston, P.G.1
Liang, C.M.2
Henry, S.3
Chabner, B.A.4
Allegra, C.J.5
-
34
-
-
0023134446
-
Role in Translation of a Triple Tandemly Repeated Sequence in the 5′- Untranslated Region of Human Thymidylate Synthase mRNA
-
Kaneda, S.; Takeishi, K.; Ayusawa, D.; Shimizu, K.; Seno, T. and Altman, S. (1987) Role in Translation of a Triple Tandemly Repeated Sequence in the 5′- Untranslated Region of Human Thymidylate Synthase mRNA. Nucleic Acids Res. 15, 1259-1270.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 1259-1270
-
-
Kaneda, S.1
Takeishi, K.2
Ayusawa, D.3
Shimizu, K.4
Seno, T.5
Altman, S.6
-
35
-
-
0025243534
-
Structural and Functional Analysis of the Human Thymidylate Synthase Gene
-
Kaneda, S.; Nalbantoglu, J.; Takeishi, K.; Shimizu, K.; Gotoh, O.; Seno, T. and Ayusawa, D. (1990) Structural and Functional Analysis of the Human Thymidylate Synthase Gene. J. Biol. Chem. 265, 20277-20284.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20277-20284
-
-
Kaneda, S.1
Nalbantoglu, J.2
Takeishi, K.3
Shimizu, K.4
Gotoh, O.5
Seno, T.6
Ayusawa, D.7
-
36
-
-
0033822956
-
Refinement of Regions with Allelic Loss on Chromosome 18p11.2 and 18q12.2 in Esophageal Squamous Cell Carcinoma
-
Karkera, J.D.; Ayache, S.; Ransome, R. J., Jr.; Jackson, M. A.; Elsayem, A. F.; Sridhar, R.; Detera-Wadleigh, S. D. and Wadleigh, R. G. (2000) Refinement of Regions with Allelic Loss on Chromosome 18p11.2 and 18q12.2 in Esophageal Squamous Cell Carcinoma. Clin. Cancer Res. 6, 3565-3569.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3565-3569
-
-
Karkera, J.D.1
Ayache, S.2
Ransome Jr., R.J.3
Jackson, M.A.4
Elsayem, A.F.5
Sridhar, R.6
Detera-Wadleigh, S.D.7
Wadleigh, R.G.8
-
37
-
-
0033941117
-
Thymidylate Synthase Expression Correlates Closely with E2F1 Expression in Colon Cancer
-
Kasahara, M.; Takahashi, Y.; Nagata, T.; Asai, S.; Eguchi, T.; Ishii, Y.; Fujii, M. and Ishikawa, K. (2000) Thymidylate Synthase Expression Correlates Closely with E2F1 Expression in Colon Cancer. Clin. Cancer Res. 6, 2707-2711.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2707-2711
-
-
Kasahara, M.1
Takahashi, Y.2
Nagata, T.3
Asai, S.4
Eguchi, T.5
Ishii, Y.6
Fujii, M.7
Ishikawa, K.8
-
38
-
-
0033427561
-
Polymorphic Tandem Repeats in the Thymidylate Synthase Gene is Associated with its Protein Expression in Human Gastrointestinal Cancers
-
Kawakami, K.; Omura, K.; Kanehira, E. and Watanabe, Y. (1999) Polymorphic Tandem Repeats in the Thymidylate Synthase Gene is Associated with its Protein Expression in Human Gastrointestinal Cancers. Anticancer Res. 19, 3249-3252.
-
(1999)
Anticancer Res.
, vol.19
, pp. 3249-3252
-
-
Kawakami, K.1
Omura, K.2
Kanehira, E.3
Watanabe, Y.4
-
39
-
-
0035064464
-
Methylenetetrahydrofolate Reductase Polymorphism is Associated with Folate Pool in Gastrointestinal Cancer Tissue
-
Kawakami, K.; Omura, K.; Kanehira, E. and Watanabe, G. (2001a) Methylenetetrahydrofolate Reductase Polymorphism is Associated with Folate Pool in Gastrointestinal Cancer Tissue. Anticancer Res. 21, 285-289.
-
(2001)
Anticancer Res.
, vol.21
, pp. 285-289
-
-
Kawakami, K.1
Omura, K.2
Kanehira, E.3
Watanabe, G.4
-
40
-
-
0035671827
-
Different Lengths of a Polymorphic Repeat Sequence in the Thymidylate Synthase Gene Affect Translational Efficiency but not its Gene Expression
-
Kawakami, K.; Salonga, D.; Park, J. M.; Danenberg, K. D.; Uetake, H.; Brabender, J.; Omura, K.; Watanabe, G. and Danenberg, P. V. (2001b) Different Lengths of a Polymorphic Repeat Sequence in the Thymidylate Synthase Gene Affect Translational Efficiency but not its Gene Expression. Clin. Cancer Res. 7, 4096-4101.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 4096-4101
-
-
Kawakami, K.1
Salonga, D.2
Park, J.M.3
Danenberg, K.D.4
Uetake, H.5
Brabender, J.6
Omura, K.7
Watanabe, G.8
Danenberg, P.V.9
-
41
-
-
0036868961
-
Functional Polymorphism of the Thymidylate Synthase Gene in Colorectal Cancer Accompanied by Frequent Loss of Heterozygosity
-
Kawakami, K.; Ishida, Y.; Danenberg, K. D.; Omura, K.; Watanabe, G. and Danenberg, P. V. (2002) Functional Polymorphism of the Thymidylate Synthase Gene in Colorectal Cancer Accompanied by Frequent Loss of Heterozygosity. Jpn. J. Cancer Res. 93, 1221-1229.
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 1221-1229
-
-
Kawakami, K.1
Ishida, Y.2
Danenberg, K.D.3
Omura, K.4
Watanabe, G.5
Danenberg, P.V.6
-
42
-
-
0141507954
-
Identification and Functional Analysis of Single Nucleotide Polymorphism in the Tandem Repeat Sequence of Thymidylate Synthase Gene
-
Kawakami, K. and Watanabe, G. (2003a) Identification and Functional Analysis of Single Nucleotide Polymorphism in the Tandem Repeat Sequence of Thymidylate Synthase Gene. Cancer Res. 63, 6004-6007.
-
(2003)
Cancer Res.
, vol.63
, pp. 6004-6007
-
-
Kawakami, K.1
Watanabe, G.2
-
43
-
-
0346103808
-
The Folate Pool in Colorectal Cancers is Associated with DNA Hypermethylation and with a Polymorphism in Methylenetetrahydrofolate Reductase
-
Kawakami, K.; Ruszkiewicz, A.; Bennett, G.; Moore, J.; Watanabe, G. and Iacopetta, B. (2003b) The Folate Pool in Colorectal Cancers is Associated with DNA Hypermethylation and with a Polymorphism in Methylenetetrahydrofolate Reductase. Clin. Cancer Res. 9, 5860-5865.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5860-5865
-
-
Kawakami, K.1
Ruszkiewicz, A.2
Bennett, G.3
Moore, J.4
Watanabe, G.5
Iacopetta, B.6
-
44
-
-
0037161062
-
Polymorphism of the Thymidylate Synthase Gene and Outcome of Acute Lymphoblastic Leukaemia
-
Krajinovic, M., Costea, I. and Chiasson, S. (2002) Polymorphism of the Thymidylate Synthase Gene and Outcome of Acute Lymphoblastic Leukaemia. Lancet 359, 1033-1034.
-
(2002)
Lancet
, vol.359
, pp. 1033-1034
-
-
Krajinovic, M.1
Costea, I.2
Chiasson, S.3
-
45
-
-
0037346011
-
Thymidylate Synthase Gene Polymorphism and its Association with Relapse in Childhood B-cell Precursor Acute Lymphoblastic Leukemia
-
Lauten, M.; Asgedom, G.; Welte, K., Schrappe, M. and Stanulla, M. (2003) Thymidylate Synthase Gene Polymorphism and its Association with Relapse in Childhood B-cell Precursor Acute Lymphoblastic Leukemia. Haematologica 88, 353-354.
-
(2003)
Haematologica
, vol.88
, pp. 353-354
-
-
Lauten, M.1
Asgedom, G.2
Welte, K.3
Schrappe, M.4
Stanulla, M.5
-
46
-
-
0038387494
-
5-fluorouracil: Mechanisms of Action and Clinical Strategies
-
Longley, D. B.; Harkin, D. P. and Johnston, P. G. (2003) 5-fluorouracil: Mechanisms of Action and Clinical Strategies. Nat. Rev. Cancer 3, 330-338.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
47
-
-
0036102129
-
Length Polymorphism of Thymidylate Synthase Regulatory Region in Chinese Populations and Evolution of the Novel Alleles
-
Luo, H. R.; Lu, X. M.; Yao, Y. G.; Horie, N., Takeishi, K.; Jorde, L. B. and Zhang, Y. P. (2002) Length Polymorphism of Thymidylate Synthase Regulatory Region in Chinese Populations and Evolution of the Novel Alleles. Biochem. Genet. 40, 41-51.
-
(2002)
Biochem. Genet.
, vol.40
, pp. 41-51
-
-
Luo, H.R.1
Lu, X.M.2
Yao, Y.G.3
Horie, N.4
Takeishi, K.5
Jorde, L.B.6
Zhang, Y.P.7
-
48
-
-
0037567591
-
A Novel Single Nucleotide Polymorphism within the 5′ Tandem Repeat Polymorphism of the Thymidylate Synthase Gene Abolishes USF-1 Binding and Alters Transcriptional Activity
-
Mandola, M.V.; Stoehlmacher, J.; Muller-Weeks, S.; Cesarone, G.; Yu, M. C.; Lenz, H. J.; Ladner, R. D. (2003) A Novel Single Nucleotide Polymorphism within the 5′ Tandem Repeat Polymorphism of the Thymidylate Synthase Gene Abolishes USF-1 Binding and Alters Transcriptional Activity. Cancer Res. 63, 2898-2904.
-
(2003)
Cancer Res.
, vol.63
, pp. 2898-2904
-
-
Mandola, M.V.1
Stoehlmacher, J.2
Muller-Weeks, S.3
Cesarone, G.4
Yu, M.C.5
Lenz, H.J.6
Ladner, R.D.7
-
49
-
-
0033564283
-
Ethnic Variation in the Thymidylate Synthase Enhancer Region Polymorphism Among Caucasian and Asian Populations
-
Marsh, S.; Collie Duguid, E. S.; Li, T.; Liu, X. and McLeod, H. L. (1999) Ethnic Variation in the Thymidylate Synthase Enhancer Region Polymorphism Among Caucasian and Asian Populations. Genomics 58, 310-312.
-
(1999)
Genomics
, vol.58
, pp. 310-312
-
-
Marsh, S.1
Collie Duguid, E.S.2
Li, T.3
Liu, X.4
McLeod, H.L.5
-
50
-
-
0034548477
-
Novel Thymidylate Synthase Enhancer Region Alleles in African Populations
-
Marsh, S.; Ameyaw, M. M.; Githang'a, J.; Indalo, A.; Ofori-Adjei, D. and McLeod, H. L. (2000) Novel Thymidylate Synthase Enhancer Region Alleles in African Populations. Hum. Mutat. 16, 528.
-
(2000)
Hum. Mutat.
, vol.16
, pp. 528
-
-
Marsh, S.1
Ameyaw, M.M.2
Githang'a, J.3
Indalo, A.4
Ofori-Adjei, D.5
McLeod, H.L.6
-
51
-
-
0035430487
-
Polymorphism in the Thymidylate Synthase Promoter Enhancer Region in Colorectal Cancer
-
Marsh, S.; McKay, J. A.; Cassidy, J. and McLeod, H. L. (2001) Polymorphism in the Thymidylate Synthase Promoter Enhancer Region in Colorectal Cancer. Int. J. Oncol. 19, 383-386.
-
(2001)
Int. J. Oncol.
, vol.19
, pp. 383-386
-
-
Marsh, S.1
McKay, J.A.2
Cassidy, J.3
McLeod, H.L.4
-
52
-
-
0037036689
-
Outcomes and Toxicity in African-american and Caucasian Patients in a Randomized Adjuvant Chemotherapy Trial for Colon Cancer
-
McCollum, A. D.; Catalano, P. J.; Haller, D. G.; Mayer, R. J.; Macdonald, J. S.; Benson, A. B., 3rd and Fuchs, C. S. (2002) Outcomes and Toxicity in African-american and Caucasian Patients in a Randomized Adjuvant Chemotherapy Trial for Colon Cancer. J. Natl. Cancer Inst. 94, 1160-1167.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1160-1167
-
-
McCollum, A.D.1
Catalano, P.J.2
Haller, D.G.3
Mayer, R.J.4
Macdonald, J.S.5
Benson III, A.B.6
Fuchs, C.S.7
-
53
-
-
0000163968
-
Dihydropyrimidine Dehydrogenase Deficiency and Fluorouracil-related Toxicity
-
Milano, G.; Etienne, M. C.; Pierrefite, V.; Barberi-Heyob, M.; Deporte-Fety, R. and Renee, N. (1999) Dihydropyrimidine Dehydrogenase Deficiency and Fluorouracil-related Toxicity. Br. J. Cancer 79, 627-630.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 627-630
-
-
Milano, G.1
Etienne, M.C.2
Pierrefite, V.3
Barberi-Heyob, M.4
Deporte-Fety, R.5
Renee, N.6
-
55
-
-
0035864968
-
Genetic Changes in Colorectal Carcinoma Tumors with Liver Metastases Analyzed by Comparative Genomic Hybridization and DNA Ploidy
-
Nakao, K.; Shibusawa, M.; Ishihara, A.; Yoshizawa, H.; Tsunoda, A.; Kusano, M.; Kurose, A.; Makita, T. and Sasaki, K. (2001) Genetic Changes in Colorectal Carcinoma Tumors with Liver Metastases Analyzed by Comparative Genomic Hybridization and DNA Ploidy. Cancer 91, 721-726.
-
(2001)
Cancer
, vol.91
, pp. 721-726
-
-
Nakao, K.1
Shibusawa, M.2
Ishihara, A.3
Yoshizawa, H.4
Tsunoda, A.5
Kusano, M.6
Kurose, A.7
Makita, T.8
Sasaki, K.9
-
56
-
-
0029149035
-
The Number of 5-fluoro-2′-deoxyuridine-5′-monophosphate Binding Sites and Reduced Folate Pool in Human Colorectal Carcinoma Tissues: Changes After Tegafur and Uracil Treatment
-
Omura, K.; Kawakami, K.; Kanehira, E.; Nagasato, A.; Kawashima, S.; Tawaraya, K.; Watanabe, S.; Hirano, K.; Shirasaka, T. and Watanabe, Y. (1995) The Number of 5-fluoro-2′-deoxyuridine-5′-monophosphate Binding Sites and Reduced Folate Pool in Human Colorectal Carcinoma Tissues: Changes After Tegafur and Uracil Treatment. Cancer Res. 55, 3897-3901.
-
(1995)
Cancer Res.
, vol.55
, pp. 3897-3901
-
-
Omura, K.1
Kawakami, K.2
Kanehira, E.3
Nagasato, A.4
Kawashima, S.5
Tawaraya, K.6
Watanabe, S.7
Hirano, K.8
Shirasaka, T.9
Watanabe, Y.10
-
57
-
-
0036355046
-
Thymidylate Synthase Gene Polymorphism Predicts Response to Capecitabine in Advanced Colorectal Cancer
-
Park, D. J.; Stoehlmacher, J.; Zhang, W.; Tsao-Wei, D.; Groshen, S. and Lenz, H. J. (2002) Thymidylate Synthase Gene Polymorphism Predicts Response to Capecitabine in Advanced Colorectal Cancer. Int. J. Colorectal Dis. 17, 46-49.
-
(2002)
Int. J. Colorectal Dis.
, vol.17
, pp. 46-49
-
-
Park, D.J.1
Stoehlmacher, J.2
Zhang, W.3
Tsao-Wei, D.4
Groshen, S.5
Lenz, H.J.6
-
58
-
-
0035750549
-
Thymidylate Synthase Gene Polymorphism Determines Response and Toxicity of 5-FU Chemotherapy
-
Pullarkat, S. T.; Stoehlmacher, J.; Ghaderi, V.; Xiong, Y. P., Ingles, S. A.; Sherrod, A.; Warren, R.; Tsao-Wei, D.; Groshen, S. and Lenz, H. J. (2001) Thymidylate Synthase Gene Polymorphism Determines Response and Toxicity of 5-FU Chemotherapy. Pharmacogenomics J. 1, 65-70.
-
(2001)
Pharmacogenomics J.
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
Xiong, Y.P.4
Ingles, S.A.5
Sherrod, A.6
Warren, R.7
Tsao-Wei, D.8
Groshen, S.9
Lenz, H.J.10
-
59
-
-
0032533513
-
Comparative Genomic Hybridization Analysis of Chromosomal Alterations Induced by the Development of Resistance to Thymidylate Synthase Inhibitors
-
Rooney, P. H.; Stevenson, D. A.; Marsh, S.; Johnston, P. G.; Haites, N. E.; Cassidy, J. and McLeod, H. L. (1998) Comparative Genomic Hybridization Analysis of Chromosomal Alterations Induced by the Development of Resistance to Thymidylate Synthase Inhibitors. Cancer Res. 58, 5042-5045.
-
(1998)
Cancer Res.
, vol.58
, pp. 5042-5045
-
-
Rooney, P.H.1
Stevenson, D.A.2
Marsh, S.3
Johnston, P.G.4
Haites, N.E.5
Cassidy, J.6
McLeod, H.L.7
-
60
-
-
0035900809
-
Colorectal Cancer Genomics: Evidence for Multiple Genotypes Which Influence Survival
-
Rooney, P. H.; Boonsong, A.; McKay, J. A.; Marsh, S.; Stevenson, D. A.; Murray, G. I.; Curran, S.; Haites, N. E.; Cassidy, J. and McLeod, H. L. (2001) Colorectal Cancer Genomics: Evidence for Multiple Genotypes Which Influence Survival. Br. J. Cancer 85, 1492-1498.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 1492-1498
-
-
Rooney, P.H.1
Boonsong, A.2
McKay, J.A.3
Marsh, S.4
Stevenson, D.A.5
Murray, G.I.6
Curran, S.7
Haites, N.E.8
Cassidy, J.9
McLeod, H.L.10
-
61
-
-
0034048729
-
Colorectal Tumors Responding to 5-fluorouracil have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase and Thymidine Phosphorylase
-
Salonga, D.; Danenberg, K. D.; Johnson, M.; Metzger, R.; Groshen, S.; Tsao-Wei, D. D.; Lenz, H. J.; Leichman, C. G.; Leichman, L.; Diasio, R. B. and Danenberg, P. V. (2000) Colorectal Tumors Responding to 5-fluorouracil have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase and Thymidine Phosphorylase. Clin. Cancer Res. 6, 1322-1327.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
Lenz, H.J.7
Leichman, C.G.8
Leichman, L.9
Diasio, R.B.10
Danenberg, P.V.11
-
62
-
-
0034484473
-
Failure of Detection of the Tyrosine to Histidine Substitution at the Residue 33 of Thymidylate Synthase in Human Colorectal Cancer. A Preliminary Study
-
Sanguedolce, R.; Alessandro, R.; De Leo, G.; Gullotti, L.; Sanguedolce, F.; Vultaggio, G.; Diana, G.; Cirello, B. and Rausa, L. (2000) Failure of Detection of the Tyrosine to Histidine Substitution at the Residue 33 of Thymidylate Synthase in Human Colorectal Cancer. A Preliminary Study. Anticancer Res. 20, 4347-4350.
-
(2000)
Anticancer Res.
, vol.20
, pp. 4347-4350
-
-
Sanguedolce, R.1
Alessandro, R.2
De Leo, G.3
Gullotti, L.4
Sanguedolce, F.5
Vultaggio, G.6
Diana, G.7
Cirello, B.8
Rausa, L.9
-
63
-
-
0037093272
-
Polymorphisms in the Thymidylate Synthase and Serine Hydroxymethyltransferase Genes and Risk of Adult Acute Lymphocytic Leukemia
-
Skibola, C. F.; Smith, M. T.; Hubbard, A.; Shane, B.; Roberts, A. C.; Law, G. R.; Rollinson, S.; Roman, E.; Cartwright, R. A. and Morgan, G. J. (2002) Polymorphisms in the Thymidylate Synthase and Serine Hydroxymethyltransferase Genes and Risk of Adult Acute Lymphocytic Leukemia. Blood 99, 3786-3791.
-
(2002)
Blood
, vol.99
, pp. 3786-3791
-
-
Skibola, C.F.1
Smith, M.T.2
Hubbard, A.3
Shane, B.4
Roberts, A.C.5
Law, G.R.6
Rollinson, S.7
Roman, E.8
Cartwright, R.A.9
Morgan, G.J.10
-
64
-
-
0021428547
-
Molecular Cloning of Genomic DNA Segments Partially Coding for Human Thymidylate Synthase from the Mouse Cell Transformant
-
Takeishi, K.; Ayusawa, D.; Kaneda, S.; Shimizu, K. and Seno, T. (1984) Molecular Cloning of Genomic DNA Segments Partially Coding for Human Thymidylate Synthase from the Mouse Cell Transformant. J. Biochem. 95, 1477-1483.
-
(1984)
J. Biochem.
, vol.95
, pp. 1477-1483
-
-
Takeishi, K.1
Ayusawa, D.2
Kaneda, S.3
Shimizu, K.4
Seno, T.5
-
65
-
-
0022431983
-
Nucleotide Sequence of a Functional cDNA for Human Thymidylate Synthase
-
Takeishi, K.; Kaneda, S.; Ayusawa, D.; Shimizu, K.; Gotoh, O. and Seno, T. (1985) Nucleotide Sequence of a Functional cDNA for Human Thymidylate Synthase. Nucleic Acids Res. 13, 2035-2043.
-
(1985)
Nucleic Acids Res.
, vol.13
, pp. 2035-2043
-
-
Takeishi, K.1
Kaneda, S.2
Ayusawa, D.3
Shimizu, K.4
Gotoh, O.5
Seno, T.6
-
66
-
-
0024437529
-
Human Thymidylate Synthase Gene: Isolation of Phage Clones which Cover a Functionally Active Gene and Structural Analysis of the Region Upstream from the Translation Initiation Codon
-
Takeishi, K.; Kaneda, S.; Ayusawa, D.; Shimizu, K.; Gotoh, O. and Seno, T. (1989) Human Thymidylate Synthase Gene: Isolation of Phage Clones which Cover a Functionally Active Gene and Structural Analysis of the Region Upstream from the Translation Initiation Codon. J. Biochem. 106, 575-583.
-
(1989)
J. Biochem.
, vol.106
, pp. 575-583
-
-
Takeishi, K.1
Kaneda, S.2
Ayusawa, D.3
Shimizu, K.4
Gotoh, O.5
Seno, T.6
-
67
-
-
0032585642
-
Novel Regions of Allelic Deletion on Chromosome 18p in Tumors of the Lung, Brain and Breast
-
Tran, Y.; Benbatoul, K.; Gorse, K.; Rempel, S.; Futreal, A.; Green, M. and Newsham, I. (1998) Novel Regions of Allelic Deletion on Chromosome 18p in Tumors of the Lung, Brain and Breast. Oncogene 17, 3499-3505.
-
(1998)
Oncogene
, vol.17
, pp. 3499-3505
-
-
Tran, Y.1
Benbatoul, K.2
Gorse, K.3
Rempel, S.4
Futreal, A.5
Green, M.6
Newsham, I.7
-
68
-
-
0036765747
-
Thymidylate Synthase: A Novel Genetic Determinant of Plasma Homocysteine and Folate Levels
-
Trinh, B. N.; Ong, C. N.; Coetzee, G. A.; Yu, M. C. and Laird, P. W. (2002) Thymidylate Synthase: A Novel Genetic Determinant of Plasma Homocysteine and Folate Levels. Hum. Genet. 111, 299-302.
-
(2002)
Hum. Genet.
, vol.111
, pp. 299-302
-
-
Trinh, B.N.1
Ong, C.N.2
Coetzee, G.A.3
Yu, M.C.4
Laird, P.W.5
-
69
-
-
12444302837
-
Polymorphism in the Thymidylate Synthase Promoter Enhancer Region is not an Efficacious Marker for Tumor Sensitivity to 5-Fluorouracil-based Oral Adjuvant Chemotherapy in Colorectal Cancer
-
Tsuji, T.; Hidaka, S.; Sawai, T.; Nakagoe, T.; Yano, H.; Haseba, M.; Komatsu, H.; Shindou, H.; Fukuoka, H.; Yoshinaga, M.; Shibasaki, S.; Nanashima, A.; Yamaguchi, H.; Yasutake, T. and Tagawa, Y. (2003) Polymorphism in the Thymidylate Synthase Promoter Enhancer Region is not an Efficacious Marker for Tumor Sensitivity to 5-Fluorouracil-based Oral Adjuvant Chemotherapy in Colorectal Cancer. Clin. Cancer Res. 9, 3700-3704.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 3700-3704
-
-
Tsuji, T.1
Hidaka, S.2
Sawai, T.3
Nakagoe, T.4
Yano, H.5
Haseba, M.6
Komatsu, H.7
Shindou, H.8
Fukuoka, H.9
Yoshinaga, M.10
Shibasaki, S.11
Nanashima, A.12
Yamaguchi, H.13
Yasutake, T.14
Tagawa, Y.15
-
70
-
-
0842268401
-
Loss of Heterozygosity at the Thymidylate Synthase Locus on Chromosome 18 Affects Tumor Response and Survival in Individuals Heterozygous for a 28-bp Polymorphism in the TS Gene
-
Uchida, K.; Hayashi, K.; Kawakami, K; Schneider, S.; Yochim, J.M.; Kuramochi, H.; Takasaki, K.; Danenberg, K.D. and Danenberg, P.V. (2004) Loss of Heterozygosity at the Thymidylate Synthase Locus on Chromosome 18 Affects Tumor Response and Survival in Individuals Heterozygous for a 28-bp Polymorphism in the TS Gene. Clin. Cancer Res. 10, 433-439.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 433-439
-
-
Uchida, K.1
Hayashi, K.2
Kawakami, K.3
Schneider, S.4
Yochim, J.M.5
Kuramochi, H.6
Takasaki, K.7
Danenberg, K.D.8
Danenberg, P.V.9
-
71
-
-
0034518362
-
Searching Expressed Sequence Tag Databases: Discovery and Confirmation of a Common Polymorphism in the Thymidylate Synthase Gene
-
Ulrich, C. M.; Bigler, J.; Velicer, C. M.; Greene, E. A.; Farin, F. M. and Potter, J. D. (2000) Searching Expressed Sequence Tag Databases: Discovery and Confirmation of a Common Polymorphism in the Thymidylate Synthase Gene. Cancer Epidemiol. Biomarkers Prev. 9, 1381-1385.
-
(2000)
Cancer Epidemiol. Biomarkers Prev.
, vol.9
, pp. 1381-1385
-
-
Ulrich, C.M.1
Bigler, J.2
Velicer, C.M.3
Greene, E.A.4
Farin, F.M.5
Potter, J.D.6
-
72
-
-
0037096858
-
Thymidylate Synthase Promoter Polymorphism, Interaction with Folate Intake and Risk of Colorectal Adenomas
-
Ulrich, C. M.; Bigler, J.; Bostick, R.; Fosdick, L. and Potter, J. D. (2002) Thymidylate Synthase Promoter Polymorphism, Interaction with Folate Intake and Risk of Colorectal Adenomas. Cancer Res. 62, 3361-3364.
-
(2002)
Cancer Res.
, vol.62
, pp. 3361-3364
-
-
Ulrich, C.M.1
Bigler, J.2
Bostick, R.3
Fosdick, L.4
Potter, J.D.5
-
73
-
-
0041524111
-
CpG Island Methylator Phenotype is an Independent Predictor of Survival Benefit from 5-fluorouracil in Stage III Colorectal Cancer
-
Van Rijnsoever, M.; Elsaleh, H.; Joseph, D.; McCaul, K. and Iacopetta, B. (2003) CpG Island Methylator Phenotype is an Independent Predictor of Survival Benefit from 5-fluorouracil in Stage III Colorectal Cancer. Clin. Cancer Res. 9, 2898-2903.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2898-2903
-
-
Van Rijnsoever, M.1
Elsaleh, H.2
Joseph, D.3
McCaul, K.4
Iacopetta, B.5
-
74
-
-
0032868050
-
Thymidylate Synthase: A Target for Combination Therapy and Determinant of Chemotherapeutic Response in Colorectal Cancer
-
Van Triest, B. and Peters, G. J. (1999) Thymidylate Synthase: A Target for Combination Therapy and Determinant of Chemotherapeutic Response in Colorectal Cancer. Oncology 57, 179-194.
-
(1999)
Oncology
, vol.57
, pp. 179-194
-
-
Van Triest, B.1
Peters, G.J.2
-
75
-
-
0035868667
-
Polymorphisms of the Repeated Sequences in the Enhancer Region of the Thymidylate Synthase Gene Promoter may Predict Downstaging After Preoperative Chemoradiation in Rectal Cancer
-
Villafranca, E.; Okruzhnov, Y.; Dominguez, M. A.; Garcia-Foncillas, J.; Azinovic, I.; Martinez, E.; Illarramendi, J. J.; Arias, F.; Martinez Monge, R.; Salgado, E.; Angeletti, S. and Brugarolas, A. (2001) Polymorphisms of the Repeated Sequences in the Enhancer Region of the Thymidylate Synthase Gene Promoter may Predict Downstaging After Preoperative Chemoradiation in Rectal Cancer. J. Clin. Oncol. 19, 1779-1786.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1779-1786
-
-
Villafranca, E.1
Okruzhnov, Y.2
Dominguez, M.A.3
Garcia-Foncillas, J.4
Azinovic, I.5
Martinez, E.6
Illarramendi, J.J.7
Arias, F.8
Martinez Monge, R.9
Salgado, E.10
Angeletti, S.11
Brugarolas, A.12
-
76
-
-
0024514647
-
Allelotype of Colorectal Carcinomas
-
Vogelstein, B.; Fearon, E. R.; Kern, S. E.; Hamilton, S. R.; Preisinger, A. C.; Nakamura, Y. and White, R. (1989) Allelotype of Colorectal Carcinomas. Science 244, 207-211.
-
(1989)
Science
, vol.244
, pp. 207-211
-
-
Vogelstein, B.1
Fearon, E.R.2
Kern, S.E.3
Hamilton, S.R.4
Preisinger, A.C.5
Nakamura, Y.6
White, R.7
-
77
-
-
0037451804
-
Cancer Pharmacogenomics: Current and Future Applications
-
Watters, J. W. and McLeod, H. L. (2003) Cancer Pharmacogenomics: Current and Future Applications. Biochim. Biophys. Acta 1603, 99-111.
-
(2003)
Biochim. Biophys. Acta
, vol.1603
, pp. 99-111
-
-
Watters, J.W.1
McLeod, H.L.2
-
78
-
-
0034805118
-
Structural Analysis of cDNA Encoding Thymidylate Synthase in Hepatic Metastases of Human Colorectal Tumors
-
Yousef, A. M.; Davis, R. A.; Sticca, R. P. and Berger, S. H. (2001) Structural Analysis of cDNA Encoding Thymidylate Synthase in Hepatic Metastases of Human Colorectal Tumors. Int. J. Colorectal Dis. 16, 318-325.
-
(2001)
Int. J. Colorectal Dis.
, vol.16
, pp. 318-325
-
-
Yousef, A.M.1
Davis, R.A.2
Sticca, R.P.3
Berger, S.H.4
|