The influence of cyclin D1 (CCND1) 870A>G polymorphism and CCND1-thymidylate synthase (TS) gene-gene interaction on the outcome of childhood acute lymphoblastic leukaemia

Pharmacogenetics

Volumn 13, Issue 9, 2003, Pages 577-580

  Costea, Irina ^a   Moghrabi, Albert ^a,b   Krajinovic, Maja ^a,b  

^a Centre de Cancerologie Charles Bruneau   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Childhood ALL; Cyclin D1; Disease outcome; Event free survival; Polymorphism; Thymidylate synthase

Indexed keywords

METHOTREXATE; THYMIDYLATE SYNTHASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; SURVIVAL; TANDEM REPEAT;

EID: 0141426676     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200309000-00006     Document Type: Article

References (17)

1. Pui CH, Campana D, Evans WE. Childhood acute lymphoblastic leukaemia - current status and future perspectives. Lancet Oncol 2001; 2:597 - 607.
2. Krynetski EY, Evans WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology 2000; 61:136-146.
3. Hosokawa Y, Tu T, Tahara H, Smith AP, Arnold A. Absence of cycrin D1/PRAD1 point mutations in human breast cancers and parathyroid adenomas and identification of a new cycrin D1 gene polymorphism. Cancer Lett 1995; 93:165-170.
4. Betticher DC, Thatcher N, Altermatt HJ, Hoban P, Ryder WD, Heighway J. Alternate spicing produces a novel cyclin D1 transcript. Oncogene 1995; 11:1005-1011.
5. Bartkova J, Lukas J, Strauss M, Bartek J. Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 1995; 10:775-778.
6. Wang L, Habuchi T, Takahashi T, Mitsumori K, Kamoto T, Kakehi Y, et al. Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer. Carcinogenesis 2002; 23:257-264.
7. Kong S, Amos CI, Luthra R, Lynch PM, Levin B, Frazier ML. Effects of cyclin D1 porymorphism on age of onset of hereditary nonpolyposis colorectal cancer. Cancer Res 2000; 60:249-252.
8. Hochhauser D, Schnieders B, Ercikan-Abali E, Gorlick R, Muise-Helmericks R, Li WW, et al. Effect of cyclin D1 overexpression on drug sensitivity in a human fibrosarcoma cell line. J Natl Cancer Inst 1996; 88:1269-1275.
9. Li W, Fan J, Hochhauser D, Banerjee D, Zielinski Z, Almasan A, et al. Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. Proc Natl Acad Sci USA 1995; 92:10436-10440.
10. Gorlick R, Goker E, Trippett T, Waltham M, Banerjee D, Bertino JR. Intrinsic and acquired resistance to methotrexate in acute leukemia. N Engl J Med 1996; 335:1041-1048.
11. Krajinovic M, Costea I, Chiasson S. Polymorphism of the thymidylate synthase gene and outcome of acute lymphoblastic leukaemia. Lancet 2002; 359:1033-1034.
12. Laverdiere C, Chiasson S, Costea I, Moghrabi A, Krajinovic M. Polymorphism GSOA in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 2002; 100:3832-3834.
13. Olah E, Balogh E, Kajtar P, Pajor L, Jakab Z, Kiss C. Diagnostic and prognostic significance of chromosome abnormalities in childhood acute lymphoblastic leukemia. Ann NY Acad Sci 1997; 824:8-27.
14. Labuda D, Krajinovic M, Richer C, Skoll A, Sinnett H, Yotova V, et al. Rapid detection of CYP1A1, CYP2D6, and NAT variants by multiplex polymerase chain reaction and allele-specific oligonucleotide assay. Anal Biochem 1999; 275:84-92.
15. Sawa H, Ohshima TA, Ukita H, Murakami H, Chiba Y, Kamada H, et al. Alternatively spliced forms of cyclin D1 modulate entry into the cell cycle in an inverse manner. Oncogene 1998; 16:1701-1712.
16. Matthias C, Branigan K, Jahnke V, Leder K, Haas J, Heighway J, et al. Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck. Clin Cancer Res 1998; 4:2411-2418.
17. Howe D, Lynas C. The cyclin D1 alternative transcripts [a] and [b] are expressed in normal and malignant lymphocytes and their relative levels are influenced by the polymorphism at codon 241. Haematologica 2001; 86:563-569.