-
1
-
-
0036534002
-
Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
-
Allegra CJ, Parr AL, Wold LE, Mahoney MR, Sargent DJ, Johnston P, Klein P, et al. (2002) Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. J Clin Oncol 20:1735-1743
-
(2002)
J Clin Oncol
, vol.20
, pp. 1735-1743
-
-
Allegra, C.J.1
Parr, A.L.2
Wold, L.E.3
Mahoney, M.R.4
Sargent, D.J.5
Johnston, P.6
Klein, P.7
-
2
-
-
17744364074
-
Expression of thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection
-
Choi J, Lim H, Nam DK, Kim HS, Cho DY, Yi JW, Kim HC, et al. (2001) Expression of thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection. Br J Cancer 84:186-192
-
(2001)
Br J Cancer
, vol.84
, pp. 186-192
-
-
Choi, J.1
Lim, H.2
Nam, D.K.3
Kim, H.S.4
Cho, D.Y.5
Yi, J.W.6
Kim, H.C.7
-
3
-
-
0026096558
-
Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth
-
Dall'Olio F, Malagolini N, Di Stefano G, Ciambella M, SerafiniCessi F (1991) Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth. Int J Cancer 47:291-297
-
(1991)
Int J Cancer
, vol.47
, pp. 291-297
-
-
Dall'Olio, F.1
Malagolini, N.2
Di Stefano, G.3
Ciambella, M.4
SerafiniCessi, F.5
-
4
-
-
0017716458
-
Thymidylate synthetase - A target enzyme in cancer chemotherapy
-
Danenberg PV (1977) Thymidylate synthetase - a target enzyme in cancer chemotherapy. Biochim Biophys Acta 473:73-92
-
(1977)
Biochim Biophys Acta
, vol.473
, pp. 73-92
-
-
Danenberg, P.V.1
-
5
-
-
0015993325
-
Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides
-
Danenberg PV, Langenbach RJ, Heidelberger C (1974) Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides. Biochemistry 13:926-933
-
(1974)
Biochemistry
, vol.13
, pp. 926-933
-
-
Danenberg, P.V.1
Langenbach, R.J.2
Heidelberger, C.3
-
7
-
-
85036692789
-
Thymidylate synthase protein expression and activity are related to cell proliferation rate in human cancer cell lines
-
in press
-
Derenzini M, Montanaro L, Treré D, Chillà A, Tazzari PL, Dall'Olio F, Ofner D (in press) Thymidylate synthase protein expression and activity are related to cell proliferation rate in human cancer cell lines. Mol Pathol
-
Mol Pathol
-
-
Derenzini, M.1
Montanaro, L.2
Treré, D.3
Chillà, A.4
Tazzari, P.L.5
Dall'Olio, F.6
Ofner, D.7
-
8
-
-
0034114866
-
Nucleolar size indicates the rapidity of cell proliferation in cancer tissues
-
Derenzini M, Treré D, Pession A, Govoni M, Sirri V, Chieco P (2000) Nucleolar size indicates the rapidity of cell proliferation in cancer tissues. J Pathol 191:181-186
-
(2000)
J Pathol
, vol.191
, pp. 181-186
-
-
Derenzini, M.1
Treré, D.2
Pession, A.3
Govoni, M.4
Sirri, V.5
Chieco, P.6
-
9
-
-
0031946191
-
Nucleolar function and size in cancer cells
-
Derenzini M, Treré D, Pession A, Montanaro L, Sirri V, Ochs RL (1998) Nucleolar function and size in cancer cells. Am J Pathol 152:1291-1297
-
(1998)
Am J Pathol
, vol.152
, pp. 1291-1297
-
-
Derenzini, M.1
Treré, D.2
Pession, A.3
Montanaro, L.4
Sirri, V.5
Ochs, R.L.6
-
10
-
-
0036534108
-
Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy
-
Edler D, Glimelius B, Hallstrom M, Jakobsen A, Johnston PG, Magnusson I, Ragnhammar P, et al. (2002) Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. J Clin Oncol 20:1721-1728
-
(2002)
J Clin Oncol
, vol.20
, pp. 1721-1728
-
-
Edler, D.1
Glimelius, B.2
Hallstrom, M.3
Jakobsen, A.4
Johnston, P.G.5
Magnusson, I.6
Ragnhammar, P.7
-
11
-
-
0034087575
-
Thymidylate synthase expression: An independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer
-
Edler D, Hallstrom M, Johnston PG, Magnusson I, Ragnhammar P, Blomgren H (2000a) Thymidylate synthase expression: an independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer. Clin Cancer Res 6:1378-1384
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1378-1384
-
-
Edler, D.1
Hallstrom, M.2
Johnston, P.G.3
Magnusson, I.4
Ragnhammar, P.5
Blomgren, H.6
-
12
-
-
0033981858
-
Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival
-
Edler D, Kressner U, Ragnhammar P, Johnston PG, Magnusson I, Glimelius B, Pahlman L, et al. (2000b) Immunohistochemically detected thymidylate synthase in colorectal cancer: an independent prognostic factor of survival. Clin Cancer Res 6:488-492
-
(2000)
Clin Cancer Res
, vol.6
, pp. 488-492
-
-
Edler, D.1
Kressner, U.2
Ragnhammar, P.3
Johnston, P.G.4
Magnusson, I.5
Glimelius, B.6
Pahlman, L.7
-
13
-
-
0028051625
-
Accumulation of nuclear p53 and tumor progression in bladder cancer
-
Esrig D, Elmajian D, Groshen S, Freeman JA, Stein JP, Chen SC, Nichols PW, et al. (1994) Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 331:1259-1264
-
(1994)
N Engl J Med
, vol.331
, pp. 1259-1264
-
-
Esrig, D.1
Elmajian, D.2
Groshen, S.3
Freeman, J.A.4
Stein, J.P.5
Chen, S.C.6
Nichols, P.W.7
-
14
-
-
0030000639
-
Cytometric measurement of cell proliferation in echo-guided biopsies from focal lesions of the liver
-
Faccioli S, Chieco P, Gramantieri L, Stecca BA, Bolondi L (1996) Cytometric measurement of cell proliferation in echo-guided biopsies from focal lesions of the liver. Mod Pathol 9:120-125
-
(1996)
Mod Pathol
, vol.9
, pp. 120-125
-
-
Faccioli, S.1
Chieco, P.2
Gramantieri, L.3
Stecca, B.A.4
Bolondi, L.5
-
15
-
-
0033824440
-
Thymidylate synthase expression in epithelial ovarian cancer: Relationship with thymidine phosphorylase expression and prognosis
-
Fujiwaki R, Hata K, Nakayama K, Fukumoto M, Miyazaki K (2000) Thymidylate synthase expression in epithelial ovarian cancer: relationship with thymidine phosphorylase expression and prognosis. Oncology 59:152-157
-
(2000)
Oncology
, vol.59
, pp. 152-157
-
-
Fujiwaki, R.1
Hata, K.2
Nakayama, K.3
Fukumoto, M.4
Miyazaki, K.5
-
16
-
-
0026795489
-
Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
-
Johnston PG, Drake JC, Trepel J, Allegra CJ (1992) Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res 52:4306-4312
-
(1992)
Cancer Res
, vol.52
, pp. 4306-4312
-
-
Johnston, P.G.1
Drake, J.C.2
Trepel, J.3
Allegra, C.J.4
-
17
-
-
0028151449
-
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmark N, Drake JC, Chabner BA, et al. (1994) The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12:2640-2647
-
(1994)
J Clin Oncol
, vol.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
-
18
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV, et al. (1995) Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 55:1407-1412
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
-
19
-
-
0026335113
-
Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue
-
Johnston PG, Liang CM, Henry S, Chabner BA, Allegra CJ (1991) Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Cancer Res 51:6668-6676
-
(1991)
Cancer Res
, vol.51
, pp. 6668-6676
-
-
Johnston, P.G.1
Liang, C.M.2
Henry, S.3
Chabner, B.A.4
Allegra, C.J.5
-
20
-
-
0035671827
-
Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression
-
Kawakami K, Salonga D, Park JM, Danenberg KD, Uetake H, Brabender J, Omura K, et al. (2001) Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression. Clin Cancer Res 7:4096-4101
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4096-4101
-
-
Kawakami, K.1
Salonga, D.2
Park, J.M.3
Danenberg, K.D.4
Uetake, H.5
Brabender, J.6
Omura, K.7
-
21
-
-
0026458517
-
A non-organic and non-enzymatic extraction method gives higher yields of genomic DNA from whole-blood samples than do nine other methods tested
-
Lahiri DK, Bye S, Nurnberger JI Jr, Hodes ME, Crisp M (1992) A non-organic and non-enzymatic extraction method gives higher yields of genomic DNA from whole-blood samples than do nine other methods tested. J Biochem Biophys Methods 25:193-205
-
(1992)
J Biochem Biophys Methods
, vol.25
, pp. 193-205
-
-
Lahiri, D.K.1
Bye, S.2
Nurnberger J.I., Jr.3
Hodes, M.E.4
Crisp, M.5
-
22
-
-
0031213588
-
Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein
-
Lee Y, Chen Y, Chang LS, Johnson LF (1997) Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein. Exp Cell Res 234:270-276
-
(1997)
Exp Cell Res
, vol.234
, pp. 270-276
-
-
Lee, Y.1
Chen, Y.2
Chang, L.S.3
Johnson, L.F.4
-
23
-
-
14444285483
-
p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival
-
Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, et al. (1998) p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res 4:1243-1250
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1243-1250
-
-
Lenz, H.J.1
Hayashi, K.2
Salonga, D.3
Danenberg, K.D.4
Danenberg, P.V.5
Metzger, R.6
Banerjee, D.7
-
24
-
-
0035321315
-
Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa
-
Miyamoto S, Ochiai A, Boku N, Ohtsu A, Tahara M, Yoshida S, Okabe H, et al. (2001) Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa. Int J Oncol 18:705-713
-
(2001)
Int J Oncol
, vol.18
, pp. 705-713
-
-
Miyamoto, S.1
Ochiai, A.2
Boku, N.3
Ohtsu, A.4
Tahara, M.5
Yoshida, S.6
Okabe, H.7
-
25
-
-
0028351657
-
Chemotherapy for colorectal cancer
-
Moertel CG (1994) Chemotherapy for colorectal cancer. N Engl J Med 330:1136-1142
-
(1994)
N Engl J Med
, vol.330
, pp. 1136-1142
-
-
Moertel, C.G.1
-
26
-
-
0019321438
-
Cell cycle regulation of thymidylate synthetase gene expression in cultured mouse fibroblasts
-
Navaigund LG, Rossana C, Muench AJ, Johnson LF (1980) Cell cycle regulation of thymidylate synthetase gene expression in cultured mouse fibroblasts. J Biol Chem 255:7386-7390
-
(1980)
J Biol Chem
, vol.255
, pp. 7386-7390
-
-
Navaigund, L.G.1
Rossana, C.2
Muench, A.J.3
Johnson, L.F.4
-
27
-
-
0022637925
-
Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level
-
Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ (1986) Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level. Histochem J 18:5-14
-
(1986)
Histochem J
, vol.18
, pp. 5-14
-
-
Ploton, D.1
Menager, M.2
Jeannesson, P.3
Himber, G.4
Pigeon, F.5
Adnet, J.J.6
-
28
-
-
0027419982
-
Demonstration of cytokeratin intermediate filaments in oocytes of the developing and adult human ovary
-
Santini D, Ceccarelli C, Mazzoleni G, Pasquinelli G, Jasonni VM, Martinelli GN (1993) Demonstration of cytokeratin intermediate filaments in oocytes of the developing and adult human ovary. Histochemistry 99:311-319
-
(1993)
Histochemistry
, vol.99
, pp. 311-319
-
-
Santini, D.1
Ceccarelli, C.2
Mazzoleni, G.3
Pasquinelli, G.4
Jasonni, V.M.5
Martinelli, G.N.6
-
29
-
-
67049102265
-
A biomathematical approach to clinical tumor growth
-
Swhartz MA (1961) A biomathematical approach to clinical tumor growth. Cancer 14:1272-1294
-
(1961)
Cancer
, vol.14
, pp. 1272-1294
-
-
Swhartz, M.A.1
-
30
-
-
0033995850
-
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
-
Takenoue T, Nagawa H, Matsuda K, Fujii S, Nita ME, Hatano K, Kitayama J, et al. (2000) Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 7:193-198
-
(2000)
Ann Surg Oncol
, vol.7
, pp. 193-198
-
-
Takenoue, T.1
Nagawa, H.2
Matsuda, K.3
Fujii, S.4
Nita, M.E.5
Hatano, K.6
Kitayama, J.7
-
31
-
-
0034174667
-
AgNOR staining and quantification
-
Treré D (2000) AgNOR staining and quantification. Micron 31:127-131
-
(2000)
Micron
, vol.31
, pp. 127-131
-
-
Treré, D.1
-
32
-
-
0033913428
-
Expression of thymidylate synthase in relation to survival and chemosensitivity in gastric cancer patients
-
Tsujitani S, Konishi I, Suzuki K, Oka S, Gomyo Y, Matsumoto S, Hirooka Y, et al. (2000) Expression of thymidylate synthase in relation to survival and chemosensitivity in gastric cancer patients. J Exp Clin Cancer Res 19:189-195
-
(2000)
J Exp Clin Cancer Res
, vol.19
, pp. 189-195
-
-
Tsujitani, S.1
Konishi, I.2
Suzuki, K.3
Oka, S.4
Gomyo, Y.5
Matsumoto, S.6
Hirooka, Y.7
-
33
-
-
18344408584
-
Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody
-
Van Triest B, Loftus BM, Pinedo HM, Backus HH, Schoenmakers P, Telleman F, Tadema T, et al. (2000a) Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody. J Histochem Cytochem 48:755-760
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 755-760
-
-
Van Triest, B.1
Loftus, B.M.2
Pinedo, H.M.3
Backus, H.H.4
Schoenmakers, P.5
Telleman, F.6
Tadema, T.7
-
34
-
-
0032868050
-
Thymidylate synthase: A target for combination therapy and determinant of chemotherapeutic response in colorectal cancer
-
Van Triest B, Peters GJ (1999) Thymidylate synthase: a target for combination therapy and determinant of chemotherapeutic response in colorectal cancer. Oncology 57:179-194
-
(1999)
Oncology
, vol.57
, pp. 179-194
-
-
Van Triest, B.1
Peters, G.J.2
-
35
-
-
12944293119
-
Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer
-
Van Triest B, Pinedo HM, Blaauwgeers JL, van Diest PJ, Schoenmakers PS, Voorn DA, Smid K, et al. (2000b) Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer. Clin Cancer Res 6:1063-1072
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1063-1072
-
-
Van Triest, B.1
Pinedo, H.M.2
Blaauwgeers, J.L.3
Van Diest, P.J.4
Schoenmakers, P.S.5
Voorn, D.A.6
Smid, K.7
-
36
-
-
0035868667
-
Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer
-
Villafranca E, Okruzhnov Y, Dominguez MA, Garcia-Foncillas J, Azinovic I, Martinez E, Illarramendi JJ, et al. (2001) Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J Clin Oncol 19:1779-1786
-
(2001)
J Clin Oncol
, vol.19
, pp. 1779-1786
-
-
Villafranca, E.1
Okruzhnov, Y.2
Dominguez, M.A.3
Garcia-Foncillas, J.4
Azinovic, I.5
Martinez, E.6
Illarramendi, J.J.7
-
37
-
-
0035555656
-
Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma
-
Wong NA, Brett L, Stewart M, Leitch A, Longley DB, Dunlop MG, Johnston PG, et al. (2001) Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma. Br J Cancer 85:1937-1943
-
(2001)
Br J Cancer
, vol.85
, pp. 1937-1943
-
-
Wong, N.A.1
Brett, L.2
Stewart, M.3
Leitch, A.4
Longley, D.B.5
Dunlop, M.G.6
Johnston, P.G.7
-
38
-
-
0031941249
-
A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
-
Yamachika T, Nakanishi H, Inada K, Tsukamoto T, Kato T, Fukushima M, Inoue M, et al. (1998) A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 82:70-77
-
(1998)
Cancer
, vol.82
, pp. 70-77
-
-
Yamachika, T.1
Nakanishi, H.2
Inada, K.3
Tsukamoto, T.4
Kato, T.5
Fukushima, M.6
Inoue, M.7
|