Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 15, 2004, Pages 4107-4111

  Kamal, Ahmed ^a   Srinivas, O ^a   Ramulu, P ^a   Ramesh, G ^a   Kumar, P Praveen ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Acridine; Acridone; DNA binding affinity; In vitro anticancer activity; Pyrrolobenzodiazepine

Indexed keywords

ACRIDINE DERIVATIVE; ACRIDONE DERIVATIVE; ANTINEOPLASTIC AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CHEMICAL REACTION; CONCENTRATION RESPONSE; DNA BINDING; DRUG EFFECT; DRUG SYNTHESIS; REACTION ANALYSIS;

ACRIDINES; BENZODIAZEPINES; BINDING SITES; DNA; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 3042553996     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.087     Document Type: Article

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