Synthesis of C-8 methanesulphonate substituted pyrrolobenzodiazepines as potential antitumour agents

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 20, 2003, Pages 3517-3519

  Kamal, Ahmed ^a   Ramulu, P ^a   Srinivas, O ^a   Ramesh, G ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZODIAZEPINE DERIVATIVE; MESYLIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; REACTION ANALYSIS; SUBSTITUTION REACTION;

EID: 0141739811     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00738-8     Document Type: Article

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27. 3) δ 1.80-2.40 (m, 4H), 3.00 (s, 3H), 3.40-3.85 (m, 2H), 3.95 (s, 3H), 4.05-4.40 (m, 3H), 4.40-4.55 (m, 2H), 6.82 (s, 1H), 7.5 (s, 1H), 7.65 (d, 1H, J=4.4 Hz); MS (EI) m/z 368.