Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1, 2-a]pyridines as antiprotozoal agents

Journal of Medicinal Chemistry

Volumn 47, Issue 14, 2004, Pages 3658-3664

  Ismail, Mohamed A ^a   Brun, Reto ^b   Wenzler, Tanja ^b   Tanious, Farial A ^a   Wilson, W David ^a   Boykin, David W ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 (4 AMIDINOPHENYL)FURAN 2 YL] 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 6 CARBOXAMIDINE; 2 [5 (4 AMIDINOPHENYL)FURAN 2 YL]IMIDAZO[1,2 A]PYRIDINE 6 CARBOXAMIDINE; 5,6,7,8 TETRAHYDRO IMIDAZO[1,2 A]PYRIDINE DERIVATIVE; ACETIC ACID; ACETIC ACID DERIVATIVE; ACETIC ACID ETHYL ESTER; ALCOHOL; ANTIPROTOZOAL AGENT; BORONIC ACID DERIVATIVE; CYANIDE; DIAMIDINE DERIVATIVE; DIMETHYL SULFATE; FURAN DERIVATIVE; IMIDAZO[1,2 A]PYRIDINE DERIVATIVE; IMIDAZOLE DERIVATIVE; N BROMOSUCCINIMIDE; N METHOXY 2 [5 [4 (N METHOXYAMIDINO)PHENYL]FURAN 2 YL]IMIDAZO[1,2 A]PYRIDINE 6 CARBOXAMIDINE; NITRILE; PRODRUG; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; BROMINATION; DRUG DNA BINDING; HYDROGENATION; IC 50; METHYLATION; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; POLYMERIZATION; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION; TRYPANOSOMA RHODESIENSE;

ANIMALS; ANTIMALARIALS; ANTIPROTOZOAL AGENTS; IMIDAZOLES; MICE; PLASMODIUM FALCIPARUM; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 3042552194     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0400092     Document Type: Article

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