Synthesis and Antiprotozoal Activity of Aza-Analogues of Furamidine

Journal of Medicinal Chemistry

Volumn 46, Issue 22, 2003, Pages 4761-4769

  Ismail, Mohamed A ^a   Brun, Reto ^b   Easterbrook, Judy D ^b   Tanious, Farial A ^a   Wilson, W David ^a   Boykin, David W ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 BIS(TRI N BUTYLSTANNYL)FURAN; 2,5 BIS[2 AMIDINO 5 PYRIDYL]FURAN ACETATE; 4 CYANOPHENYLBORONIC ACID; 5 [5 (4 CARBAMIMIDOYLPHENYL)FURAN 2 YL]PYRIDINE 2 CARBOXAMIDINE ACETATE; 6 (FURAN 2 YL)NICOTINONITRILE; 6 [5 (3 CARBAMIMIDOYLPHENYL)FURAN 2 YL]NICOTINAMIDINE ACETATE; 6 [5 (4 AMIDINOPHENYL)FURAN 2 YL]NICOTINAMIDINE; 6 [5 (4 CYANOPHENYL)FURAN 2 YL]NICOTINONITRILE; BIS O ACETOXYAMIDOXIME; BORONIC ACID DERIVATIVE; DIAMIDINE DERIVATIVE; DIMETHYL SULFATE; FURAMIDINE DERIVATIVE; FURAN DERIVATIVE; HALIDE; HETEROCYCLIC COMPOUND; N BROMOSUCCINIMIDE; N ETHOXY 6 [5 [4 (N ETHOXYCARBAMIMIDOYL)PHENYL]FURAN 2 YL]NICOTINAMIDINE; N METHOXY 5 [5 [4 (N METHOXYCARBAMIMIDOYL)PHENYL]FURAN 2 YL]PYRIDINE 2 CARBOXAMIDINE; N METHOXY 6 [5 [4 (N METHOXYAMIDINO)PHENYL]FURAN 2 YL]NICOTINAMIDINE; NICOTINIC ACID DERIVATIVE; NITRILE; OXIME; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; IC 50; IN VITRO STUDY; IN VIVO STUDY; METHYLATION; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PROTOZOAL INFECTION; STILLE REACTION; SUZUKI REACTION; TRYPANOSOMA RHODESIENSE;

ANIMALS; ANTIMALARIALS; ANTIPROTOZOAL AGENTS; AZA COMPOUNDS; BENZAMIDINES; MICE; PLASMODIUM FALCIPARUM; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 0142028913     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0302602     Document Type: Article

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