2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents

Journal of Medicinal Chemistry

Volumn 42, Issue 12, 1999, Pages 2260-2265

  Francesconi, Iris ^a   Wilson, W David ^a   Tanious, Farial A ^a   Hall, James E ^b   Bender, Brendan C ^b   Tidwell, Richard R ^b   McCurdy, Donald ^b   Boykin, David W ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 BIS(4 AMIDINOPHENYL) 3,5 DIMETHYLFURAN; 2,4 BIS(4 AMIDINOPHENYL)FURAN; 2,4 BIS[4 [N (CYCLOPENTYLAMIDINO)PHENYL]]FURAN; 2,4 BIS[4 [N (CYCLOPROPYLAMIDINO)PHENYL]]FURAN; 2,4 BIS[4 [N (ISOPROPYLAMIDINO)PHENYL]] 3,5 DIMETHYLFURAN; 2,4 BIS[4 [N (ISOPROPYLAMIDINO)PHENYL]]FURAN; DIAMIDINE DERIVATIVE; FURAN DERIVATIVE; PENTAMIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PNEUMOCYSTIS PNEUMONIA; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMIDINES; ANIMALS; ANTIFUNGAL AGENTS; DNA; FURANS; IMMUNOCOMPROMISED HOST; PNEUMONIA, PNEUMOCYSTIS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033578038     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990071c     Document Type: Article

References (17)

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