Targeting the minor groove of DNA: Crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2

Journal of Medicinal Chemistry

Volumn 39, Issue 23, 1996, Pages 4554-4562

  Trent, John O ^a   Clark, George R ^b   Kumar, Arvind ^c   Wilson, W David ^c   Boykin, David W ^c   Hall, James Edwin ^d   Tidwell, Richard R ^d   Blagburn, Byron L ^e   Neidle, Stephen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c GEORGIA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 BIS[4 (N CYCLOPROPYLAMIDINO)PHENYL]FURAN DIHYDROCHLORIDE; 2,5 BIS[[4 (N ISOPROPYL)AMIDINO]PHENYL]FURAN DIHYDROCHLORIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTIPROTOZOAL AGENT; CONGOCIDINE; DIMINAZENE ACETURATE; DISTAMYCIN A; FURAN DERIVATIVE; PENTAMIDINE; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYPTOSPORIDIUM PARVUM; CRYSTAL STRUCTURE; DNA STRUCTURE; DRUG DNA BINDING; DRUG STRUCTURE; INTRAVENOUS DRUG ADMINISTRATION; MOLECULAR MODEL; NONHUMAN; OPPORTUNISTIC INFECTION; ORAL DRUG ADMINISTRATION; PNEUMOCYSTIS CARINII; PROTOZOAL INFECTION; RAT;

CRYSTALLOGRAPHY, X-RAY; DIMINAZENE; DNA; FURANS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES;

EID: 0029803441     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9604484     Document Type: Article

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