Synthesis and DNA interactions of benzimidazole dications which have activity against opportunistic infections

Journal of Medicinal Chemistry

Volumn 39, Issue 7, 1996, Pages 1452-1462

  Lombardy, Richard L ^a   Tanious, Farial A ^a   Ramachandran, Kishore ^b   Tidwell, Richard R ^b   Wilson, W David ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 4',6 DIAMIDINO 2 PHENYLINDOLE; BENZIMIDAZOLE DERIVATIVE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CALCULATION; CIRCULAR DICHROISM; DNA BINDING; DNA SYNTHESIS; IONIC STRENGTH; NUCLEAR MAGNETIC RESONANCE; OPPORTUNISTIC INFECTION; PNEUMOCYSTIS PNEUMONIA; PROTEIN DNA INTERACTION;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIFUNGAL AGENTS; BASE SEQUENCE; BENZIMIDAZOLES; BINDING SITES; CIRCULAR DICHROISM; DNA; DRUG DESIGN; ETHIDIUM; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; PNEUMONIA, PNEUMOCYSTIS; POLY DA-DT; RNA; SPECTROPHOTOMETRY; THERMODYNAMICS;

EID: 0029983537     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9507946     Document Type: Article

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