Relationships between topoisomerase II inhibition, sequence-specificity and DNA binding mode of dicationic diphenylfuran derivatives

Anti-Cancer Drug Design

Volumn 14, Issue 1, 1999, Pages 47-60

  Bailly, Christian ^a   Dassonneville, Laurent ^a   Carrasco, Carolina ^a   Lucas, Delphine ^a   Kumar, Arvind ^b   Boykin, David W ^b   Wilson, W David ^b  

^a CENTRE OSCAR LAMBRET   (France)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Diphenylfurans; DNA intercalation; DNA minor groove; Pneumocystis carinii; Sequence specific binding; Topoisomerase II

Indexed keywords

DB226; DB244; DB60; DB75; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); FURAMIDINE; FURAN DERIVATIVE; FURIMIDAZOLINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA FOOTPRINTING; DNA SEQUENCE; DRUG DNA BINDING; ENZYME INHIBITION; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; BINDING SITES; DNA FOOTPRINTING; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA, BACTERIAL; DNA, SUPERHELICAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ESCHERICHIA COLI; FURANS; HUMANS; INDICATORS AND REAGENTS; POTASSIUM PERMANGANATE;

PNEUMOCYSTIS CARINII;

EID: 0032913039     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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