Dissecting the molecular mechanisms of TCR ζ chain downregulation and T cell signaling abnormalities in human systemic lupus erythematosus

International Reviews of Immunology

Volumn 23, Issue 3-4, 2004, Pages 245-263

  Nambiar, Madhusoodana P ^b   Juang, Yuang Taung ^b   Krishnan, Sandeep ^b   Tsokos, George C ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b NONE

Author keywords

Gene therapy; Gene transcription; Signaling; Systemic lupus erythematosus; T cell receptor; Ubiquitination

Indexed keywords

CD3 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

CALCIUM CELL LEVEL; CHROMATIN STRUCTURE; GENE EXPRESSION; HUMAN; LIPID MEMBRANE; LIPID RAFT; MEMBRANE STRUCTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR DOWN REGULATION; REVIEW; RNA EDITING; RNA PROCESSING; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; UBIQUITINATION;

AMINO ACID SEQUENCE; CHROMATIN; DNA-BINDING PROTEINS; DOWN-REGULATION; GENE THERAPY; HUMANS; IMMUNOGLOBULIN EPSILON-CHAINS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTORS;

EID: 3042529734     PISSN: 08830185     EISSN: None     Source Type: Journal    
DOI: 10.1080/08830180490452602     Document Type: Review

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