Translocation of tyrosine-phosphorylated TCRζ chain to glycolipid-enriched membrane domains upon T cell activation

International Immunology

Volumn 11, Issue 9, 1999, Pages 1395-1401

  Kosugi, Atsushi ^a   Saitoh, Shin Ichiroh ^a   Noda, Satoshi ^b   Yasuda, Koubun ^a   Hayashi, Fumie ^a   Ogata, Masato ^a   Hamaoka, Toshiyuki ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glycolipid enriched membrane; Microdomain; Phosphorylation; TCR; TCR chain

Indexed keywords

CD3 ANTIGEN; GLYCOLIPID; MEMBRANE LIPID; PROTEIN SUBUNIT; T LYMPHOCYTE RECEPTOR; TRITON X 100;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DNA TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SUCROSE DENSITY GRADIENT CENTRIFUGATION; T LYMPHOCYTE ACTIVATION;

EID: 0032882619     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.9.1395     Document Type: Article

References (35)

1. Weiss, A. and Littman, D. R. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
2. Wange, R. L. and Samelson, L. E. 1996. Complex complexes: signaling at the TCR. Immunity 5:197.
3. Saitoh, S.-I., Kosugi, A., Noda, S., Yamamoto, N., Ogata, M., Minami, Y., Miyake, K. and Hamaoka, T. 1995. Modulation of T cell receptor-mediated signaling pathway by thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2). J. Immunol. 155:5574.
4. Noda, S., Kosugi, A., Saitoh, S.-I., Narumiya, S. and Hamaoka, T. 1996. Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2. J. Exp. Med. 183:2355.
5. Kosugi, A., Saitoh, S.-I., Noda, S., Miyake, K., Yamashita, Y., Kimoto, M., Ogata, M. and Hamaoka, T. 1998. Physical and functional association between thymic shared antigen-1/stem cell antigen-2 and the T cell receptor complex. J. Biol. Chem. 273:12301.
6. Simons, K. and Ikonen, E. 1997. Functional rafts in cell membranes. Nature 387:569.
7. Brown, D. A. and London, E. 1997. Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes? Biochem. Biophys. Res. Commun. 240:1.
8. Anderson, R. G. W. 1993. Plasmalemmal caveolae and GPI-anchored membrane proteins. Curr. Opin. Cell Biol. 5:647.
9. Xavier, R., Brennan, T., Li, Q., McCormack, C. and Seed, B. 1998. Membrane compartmentation is required for efficient T cell activation. Immunity 8:723.
10. Zhang, W., Trible, R. P. and Samelson, L. E. 1998. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 9:239.
11. Samelson, L. E., Germain, R. N. and Schwartz, R. H. 1983. Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. Proc. Natl Acad. Sci. USA 80:6972.
12. + B cell hybridomas to H-2-restricted T cell hybridomas. Proc. Natl Acad. Sci. USA 79:3604.
13. Leo, O., Foo, M., Sachs, D. H., Samelson, L. E. and Bluestone, J. A. 1987. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc. Natl Acad. Sci. USA 84:1374.
14. Born, W., Miles, C., White, J., O'Brien, R., Freed, J. H., Marrack, P., Kappler, J. P. and Kubo, R. T. 1987. Peptide sequences of T cell receptor 8 and ychains are identical to predicted X and y proteins. Nature 330:572.
15. Punt, J. A., Kubo, R. T., Saito, T., Finkel, T. H., Kathiresan, S., Blank, K. J. and Hashimoto, Y. 1991. Surface expression of a T cell receptor β (TCR-β) chain in the absence of TCR-α, -δ, and -γ proteins. J. Exp. Med. 174:775.
16. Becker, M. L. B., Near, R., Mudgett-Hunter, M., Margolies, M. N., Kubo, R. T., Kaye, J. and Hedrick, S. M. 1989. Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice. Cell 58:911.
17. Ortega, G., Korty, P. E., Shevach, E. M. and Malek, T. R. 1986. Role of Ly-6 in lymphocyte activation I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity. J. Immunol 137:3240.
18. lck in HTLV-I-transformed T cell lines detected by an anti-Lck monoclonal antibody, MOL 171. Jpn. J. Cancer Res. 82:909.
19. ck associated with glycolipid-enriched membrane domains. J. Cell Biol. 135:1515.
20. Schnitzer, J. E., McIntosh, D. P., Dvorak, A. N., Liu, J. and Oh, P. 1995. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 269:1435.
21. Rodgers, W., Crise, B. and Rose, J. K. 1994. Signals determining protein tyrosine kinase and glycosylphosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction. Mol. Cell. Biol. 14:5384.
22. Caplan, S., Zeliger, S., Wang, L. and Baniyash, M. 1995. Cell-surface-expressed T-cell antigen-receptor C chain is associated with the cytoskeleton. Proc. Natl. Acad. Sci. USA 92:4768.
23. Kersh, E. N., Shaw, A. S. and Allen, P. M. 1998. Fidelity of T cell activation through multiple T cell receptor C phosphorylation. Science 281:572.
24. Mineo, C., James, G. L., Smart, E. J. and Anderson, R. G. W. 1996. Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane. J. Biol. Chem. 271:11930.
25. Ilangumaran, S., Briol, A. and Hoessli, D. C. 1998. CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes. Blood 91:3901.
26. lyn to detergent-resistant membrane domains accompanies cellular signaling. Proc. Natl Acad. Sci. USA 92:9201.
27. Field, K. A., Holowka, D. and Baird, B. 1997. Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains J. Biol. Chem. 272:4276.
28. Brdicka, T., Cerny, J. and Horejsi, V. 1998. T cell receptor signalling results in rapid tyrosine phosphorylation of the linker protein LAT present in detergent-resistant membrane microdomains. Biochem. Biophys. Res. Commun. 248:356.
29. Kabouridis, P. S., Magee, A. I. and Ley, S. C. 1997. S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. EMBO J. 16:4983.
30. Montixi, C., Langlet, C., Bernard, A.-N., Thimonier, J., Dubois, C., Wurbel, M.-A., Chauvin, J.-P., Pierres, M. and He, H.-T. 1998. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J. 17:5334.
31. Rodgers, W., Crise, B. and Rose, J. K. 1994. Signals determining protein tyrosine kinase and glycosylphosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction. mol. Cell Biol. 14:5384.
32. lck. Biochem. Biophys. Res. Commun. 207:868.
33. Valitutti, S. and Lanzavecchia, A. 1997. Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol. Today 18:299.
34. Viola, A. and Lanzavecchia, A. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science 273:104.
35. Valitutti, S., Müller, S., Salio, M. and Lanzavecchia, A. 1997. Degradation of T cell receptor (TCR)-CD3-ζ complexes after antigenic stimulation. J. Exp. Med. 185:1859.