Effects of a medium chain triglyceride oil mixture and α-lipoic acid diet on body composition, antioxidant status, and plasma lipid levels in the Golden Syrian hamster

Journal of Nutritional Biochemistry

Volumn 15, Issue 7, 2004, Pages 402-410

  Wollin, Stephanie D ^a   Wang, Yanwen ^a   Kubow, Stan ^a   Jones, Peter J H ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FAT; GLUTATHIONE; GLUTATHIONE DISULFIDE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LINSEED OIL; LIPOPROTEIN; MEDIUM CHAIN TRIACYLGLYCEROL; OMEGA 3 FATTY ACID; PHYTOSTEROL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID; TRIACYLGLYCEROL; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY COMPOSITION; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DIET; DIET SUPPLEMENTATION; ENERGY EXPENDITURE; FEEDING; FOOD INTAKE; HEALTH STATUS; HEART; HYPERCHOLESTEROLEMIA; LEAN BODY WEIGHT; LIPID ANALYSIS; LIPID BLOOD LEVEL; LIPID DIET; LIVER; NONHUMAN; QUANTITATIVE ANALYSIS; SYRIAN HAMSTER; TISSUE LEVEL; TOTAL BODY WATER;

ANIMALS; ANTIOXIDANTS; BODY COMPOSITION; BODY WEIGHT; CHOLESTEROL; CHOLESTEROL, DIETARY; CHOLESTEROL, HDL; CRICETINAE; DIETARY FATS, UNSATURATED; EATING; ENERGY METABOLISM; FATTY ACIDS, OMEGA-3; GLUTATHIONE; LINSEED OIL; LIPIDS; LIPOPROTEINS; LIVER; MESOCRICETUS; MYOCARDIUM; OXIDATION-REDUCTION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THIOCTIC ACID; TRIGLYCERIDES;

CRICETINAE; MESOCRICETUS AURATUS;

EID: 3042515949     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2003.12.001     Document Type: Article

References (68)

1. Health Canada. Heart Disease and Stroke in Canada. Ottawa: Health and Protection Branch-Lab Center for Disease Control, 1997
2. Westhuysen J. The oxidation hypothesis of atherosclerosis an update. Ann Clin Lab Sci. 27:1997;1-10
3. Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J Biol Chem. 272:1997;20963-20966
4. Quinn M.T., Parthasarathy S., Fong L.G., Steinberg D. Oxidatively modified low density lipoproteins a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Nat Acad Sci USA. 84:1987;2995-2998
5. Packer L., Witt E.H., Tritschler H. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med. 19:1995;227-250
6. Kagan V.E., Serbinova E.A., Forte T., Scita G., Packer L. Recycling of vitamin E in human low density lipoproteins. J Lipid Res. 33:1992;385-397
7. Marangon K., Devaraj S., Tirosh O., Packer L., Jialal I. Comparison of the effect of α-lipoic acid and α-tocopherol supplementation on measures of oxidative stress. Free Radical Biol Med. 27:1999;1114-1121
8. Lodge J.K., Traber M.G., Packer L. Thiol chelation of Cu2+ by dihydrolipoic acid prevents human low density lipoprotein peroxidation. Free Radical Biol Med. 25:1998;287-297
9. Busse E., Zimmer G., Schopohl B., Kornhuber B. Influence of alpha-lipoic acid on intracellular glutathione in vitro and in vivo. Arzneim-Forsch. 42:1992;829-831
10. Hagen T.M., Ingersoll R.T., Lykkesfeldt J., Liu J., Wehr C.M., Vinarsky V., Bartholomew J.C., Ames B.N. (R)-α-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 13:1999;411-418
11. Ivanov V.N. Effect of lipoic acid on tissue respiration in rabbits with experimental atherosclerosis. Cor et Vasa. 16:1974;141-150
12. Shih J.C. Atherosclerosis in Japanese quail and the effect of lipoic acid. Fed Proc. 42:1983;2494-2497
13. Ford I., Cotter M.A., Cameron N.E., Greaves M. The effects of treatment with α-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. Metabolism. 50:2001;868-875
14. Segermann J., Hotze A., Ulrich H., Rao G.S. Effect of α-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid, protein and glucose levels. Arzneim-Forsch. 41:1991;1294-1298
15. Caspary W.F. Physiology and pathophysiology of intestinal absorption. Am J Clin Nutr. 55S:1992;299S-308S
16. Leyton J., Drury P.J., Crawford M.A. Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr. 57:1987;383-393
17. Johnson R.C., Young S.K., Cotter R., Lin L., Rowe W.B. Medium chain triglyceride lipid emulsion metabolism and tissue distribution. Am J.Clin Nutr. 52:1990;502-508
18. Mascioli E.A., Lopes S., Randall S., Porter K.A., Kater G., Hirschberg Y., Babayan V.K., Bistrian B.R., Blackburn G.L. Serum fatty acid profiles after intravenous medium-chain triglyceride administration. Lipids. 24:1989;793-798
19. Hill J.O., Peters J.C., Swift L.L., Yang D., Sharp T., Abumrad N., Greene H.L. Changes in blood lipids during six days of overfeeding with medium or long chain triglycerides. J Lipid Res. 31:1990;407-416
20. Binnert C., Pachiaudi C., Beylot M., Hans D., Vandermander J., Chantre P., Riou J.P., Laville M. Influence of human obesity on the metabolic fate of dietary long- and medium-chain triacylglycerols. Am J Clin Nutr. 67:1998;595-601
21. Swift L.L., Hill J.O., Peters J.C., Greene H.L. Plasma lipids and lipoproteins during 6-d of maintenance feeding with long-chain, medium chain, and mixed chain triglycerides. Am J Clin Nutr. 56:1992;881-886
22. Geelen M.J.H., Schoots W.J., Bijleveld C., Beynen A.C. Dietary medium chain fatty acids raise and (n-3) polyunsaturated fatty acids lower hepatic triacylglycerol synthesis in rats. J Nutr. 125:1995;2449-2456
23. Tsai Y.H., Park S., Kovacic J., Snook J.T. Mechanisms mediating lipoprotein responses to diets with medium-chain triglyceride and lauric acid. Lipids. 34:1999;895-905
24. Cater N.B., Heller H.J., Denke M.A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am J Clin Nutr. 65:1997;41-45
25. Hainer V., Kunesova M., Stich V., Zak A., Parizkova J. The role of oils containing triacylglycerols and medium-chain fatty acids in the dietary treatment of obesity. The effect on resting energy expenditure and serum lipids. [Abstract in English] Casopis Lekaru Ceskych. 133:1994;373-375
26. Nicolosi R.J., Wilson T.A., Rogers E.J., Kritchevsky D. Effects of specific fatty acids (8 0, 14:0, cis-18:1, trans-18:1) on plasma lipoproteins, early atherogenic potential, and LDL oxidative properties in the hamster. J Lipid Res. 39:1998;1972-1980
27. Woollett L.A., Spady D.K., Dietschy J.M. Regulatory effects of the saturated fatty acids 6 0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster. J Clin Invest. 80:1992;1133-1141
28. Gylling H., Miettinen T.A. Cholesterol reduction by different plant stanol mixtures with variable fat intake. Metabolism. 48:1999;575-580
29. Miettinen T.A., Puska P., Gylling H., Vanhanen H., Vartiainen E. Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population. N Engl J Med. 333:1995;1308-1312
30. Pelletier X., Belbraouet S., Mirabel D., Mordret F., Perrin J.L., Pages X., Derby G. A diet moderately enriched in phytosterols lowers plasma cholesterol concentrations in normocholesterolemic humans. Ann Nutr Metab. 39:1995;291-295
31. Jones P.J., Ntanios F.Y., Raeini-Sarjaz M., Vanstone C. Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men. Am J Clin Nutr. 69:1999;1144-1150
32. Jones P.J., MacDougall D., Ntanios F., Vanstone C.A. Dietary phytosterols as cholesterol lowering agents in humans. Can J Physiol Pharmacol. 75:1997;217-227
33. Mantzioris E., James M.J., Gibson R.A., Cleland L.G. Dietary substitution with an α-linolenic acid-rich vegetable oil increases eicosapentaenoic acid concentrations in tissues. Am J Clin Nutr. 59:1994;1304-1309
34. Harris W.S. n-3 Fatty acids and serum lipoproteins animal studies. Am J Clin Nutr. 65S:1997;1611S-1615S
35. Singer P., Wirth M., Berger I., Heinrich B., Gödicke W., Voigt S., Taube C., Jaross W., Gehrisch S. Long chain ω3 fatty acids are the most effective polyunsaturated fatty acids for dietary prevention and treatment of cardiovascular risk factors. World Rev Nutr Dietetics. 69:1992;74-112
36. Bourque C., St-Onge M.P., Papamandjaris A.A., Cohn J.S., Jones P.J. Consumption of an oil composed of medium chain triacylglycerols, phytosterols, and n-3 fatty acids improves cardiovascular risk profile of overweight women. Metabolism. 52:2003;771-777
37. St-Onge M.P., Bourque C., Jones P.J., Ross R., Parsons W.E. Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting changes in body composition in overweight women. Int J Obesity. 27:2003;95-102
38. St-Onge M.P., Lamarche B., Mauger J.F., Jones P.J. Consumption of a functional oil rich in phtosterols and medium chain triglyceride oil improves plasma lipid profiles in men. J Nutr. 133:2003;1815-1820
39. St-Onge M.P., Ross R., Parsons W.D., Jones P.J. Medium chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obesity Res. 11:2003;395-402
40. Cha M.C., Jones P.J. Dietary fat type and energy restriction interactively influence plasma leptin concentrations in rats. J Lipid Res. 39:1998;1655-1660
41. Jones P.J., Kubow S. Lipids, sterols, and their metabolites. Shils M.E., Olson J.A., Shike M., Ross A.C. Modern Nutrition in Health and Disease. 1999;67-94 Lippincott, Williams & Wilkins, Philadelphia. 9th ed.
42. 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem. 28:1982;1379-1388
43. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 18:1972;499-502
44. Jones P.J., Scanu A.M., Schoeller D.A. Plasma cholesterol synthesis using deuterated water in humans Effect of short term food restriction. J Clin Lab Med. 111:1988;627-633
45. Pace N., Rathburn E.N. Studies on body composition III The body water and chemically combined nitrogen content in relation to fat content. J Biol Chem. 158:1945;685-691
46. Asakawa T., Matsushita S. Thiobarbituric acid test for detecting lipid peroxides. Lipids. 14:1980;401-406
47. Wong S.H., Knight J.A., Hopfer S.M., Zaharia O., Leach C.N. Jr, Sunderman F.W. Jr. Lipidperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin Chem. 33:1987;214-220
48. Poirier J., Cockell K., Hidiroglou N., Madere R., Trick K., Kubow S. The effects of vitamin E and selenium intake on oxidative stress and plasma lipids in hamsters fed fish oil. Lipids. 37:2002;1125-1133
49. Williams P.T. High-density lipoprotein cholesterol and other risk factors for coronary heart disease in female runners. N Engl J Med. 334:1996;1298-1303
50. Wood PD. A round table: The health benefits of exercise (part 1 of 2). The Physician and Sports Medicine, Minneapolis. 1987;15:115-32
51. Manninen V., Elo M.O., Frick M.H. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. J Am Med Assoc. 260:1988;641-651
52. Furberg C.D. The usefulness of information on HDL-cholesterol potential pitfalls of conventional assumptions. Curr Control Trials Cardiovasc Med. 2:2001;107-108
53. Asakura L., Lottenburg A.M., Neves M.Q., Nunes V.S., Rocha J.C., Passarelli M., Nakandakare E.R., Quintao E.C. Dietary medium chain triacylglycerol prevents the postprandial rise in plasma triacylglycerols but induces hypercholesterolemia in primary hypertriglyceridemic subjects. Am J Clin Nutr. 71:2000;701-705
54. Wardlaw G.M., Snook J.T., Park S., Patel P.K., Pendley F.C., Lee M.S., Jandacek R.J. Reflective effects of serum lipids and apolipoproteins of a caprenin-rich diet compared with diets rich in palm oil/palm kernel oil or butter. Am J Clin Nutr. 61:1995;535-542
55. Arivazhagan P., Juliet P., Panneerselvam C. Effect of DL-α-lipoic acid on the status of lipid peroxidation and antioxidants in aged rats. Pharmacol Res. 41:2000;299-303
56. Haramake N., Handelman G.J. Tissue specific pathways of alpha-lipoate reduction in mammalian systems. Fuchs J., Packer L., Zimmer G. Lipoic Acid in Health and Disease. 1997;145-162 Marcel Dekker, New York
57. Packer L., Roy S., Sen C.K. α-Lipoic acid A metabolic antioxidant and potential redox modulator of transcription. Adv Pharmacol. 38:1997;79-101
58. Jones W., Li X., Qu Z.C., Perriott L., Whitesell R.R., May J.M. Uptake, recycling, and antioxidant actions of α-lipoic acid in endothelial cells. Free Radic Biol Med. 33:2002;83-93
59. Baba N., Bracco E.F., Hashim S.A. Enhanced thermogenesis and diminished deposition of fat in response to overfeeding with diet containing medium-chain triglyceride. Am J Clin Nutr. 35:1982;678-682
60. Chanez M., Bois-Joyeux B., Arnaud M., Peret J. Metabolic effects in rats of a diet with a moderate level of medium-chain triglycerides. J Nutr. 121:1991;594-595
61. Geliebter A., Torbay N., Bracco E.F., Hashim S.A., Van Itallie T.B. Overfeeding with medium-chain triglyceride diet results in diminished deposition of fat. Am J Clin Nutr. 37:1983;1-4
62. Hwang S.G., Yano H., Kawashima R. Influence of dietary medium-chain and long-chain triglycerides on fat deposition and lipogenic enzyme activities in rats. J Am Coll Nutr. 12:1993;643-650
63. Hill J.O., Peters J.C., Lin D., Yakubu F., Greene H., Swift L. Lipid accumulation and body fat distribution is influenced by type of dietary fat fed to rats. Int J Obesity. 17:1993;223-236
64. Bach A.C., Ingenbleek Y., Frey A. The usefulness of dietary medium-chain triglycerides in body weight control fact or fancy? J Lipid Res. 37:1996;708-726
65. Gleiter C.H., Schug B.S., Hermann R., Elze M., Blume H.H., Gundert-Remy U. Influence of food intake on the bioavailability of thioctic acid enantiomers. Eur J Clin Pharmacol. 50:1996;513-514
66. Hermann R., Niebch G., Borbe H.O., Fieger-Büschges H., Ruus P., Nowak H., Riethmüller H., Peukert M., Blume H. Enantioselective pharmacokinetics and bioavailability of different racemic α-lipoic acid formulations in healthy volunteers. Eur J Pharm Sci. 4:1996;167-174
67. Biewenga G.P., Haenen G.R., Bast A. An overview of lipoate chemistry. Fuchs J., Packer L., Zimmer G. Lipoic Acid in Health and Disease. 1997;1-32 Marcel Dekker, New York
68. Morikawa T., Yasuno R., Wada H. Do animal cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria. Fed Eur Biochem Soc. 498:2001;16-21