n-3 Fatty acids and serum lipoproteins: Animal studies

American Journal of Clinical Nutrition

Volumn 65, Issue 5 SUPPL., 1997, Pages

  Harris, William S ^a  

^a SAINT LUKE S MID AMERICA HEART INSTITUTE   (United States)

Author keywords

animal studies; cholesterol; docosahexaenoic acid; Eicosapentaenoic acid; fish oil; high density lipoproteins; low density lipoproteins; n 3 fatty acid; triacylglycerol

Indexed keywords

FATTY ACID; FISH OIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIPOPROTEIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; CONFERENCE PAPER; DOG; FAT INTAKE; FEEDING; HAMSTER; HUMAN; LIPOPROTEIN METABOLISM; MONKEY; MOUSE; NONHUMAN; RABBIT; RAT; SPECIES DIFFERENCE; SWINE;

ANIMALIA; CANIS FAMILIARIS; CRICETINAE; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0030991110     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/65.5.1611S     Document Type: Conference Paper

References (62)

1. Harris WS. n-3 Fatty acids and serum lipoproteins: human studies. Am J Clin Nutr 1997;65(suppl):1645S-54S.
2. Renier G, Skamene E, DeSanctis J, Radzioch D. Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Arterioscler Thromb 1993;13:1515-24.
3. Jones PJH, Ridgen JE, Benson AP. Influence of dietary fatty acid composition on cholesterol synthesis and esterification in hamsters. Lipids 1990;25:815-20.
4. Surrette ME, Whelan J, Broughton KS, Kinsella JE. Evidence for mechanisms of the hypotriglyceridemic effect of n-3 polyunsaturated fatty acids Biochim Biophys Acta 1992;1126:199-205.
5. Surrette ME, Whelan J, Lu GP, Broughton KS, Kinsella JE. Dependence on dietary cholesterol for n-3 polyunsaturated fatty acid-induced changes in plasma cholesterol in the Syrian hamster. J Lipid Res 1992;33:263-71.
6. Aarsland A, Lundquist M, Borretsen B, Berge RK. On the effect of peroxisomal β-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats. Lipids 1990;25:546-8.
7. Chautan M, Chanussot F, Portugal H, Pauli AM, Lafont H. Effects of salmon oil and corn oil on plasma lipid level and hepato-biliary cholesterol metabolism in rats. Biochim Biophys Acta 1990;1046:40-5.
8. Choi YS, Goto S, Ikeda I, Sugano M. Effect of dietary n-3 polyunsaturated fatty acids on cholesterol synthesis and degradation in rats of different ages. Lipids 1989;24:45-50.
9. Haug A, Hostmark AT. Lipoprotein lipases, lipoproteins and tissue lipids in rats fed fish oil or coconut oil. J Nutr 1987;117:1011-7.
10. Hegsted DM, Andrus SB, Gotsis A, Portman OW. The quantitative effects of cholesterol, cholic acid and type of fat on serum cholesterol and vascular sudanophilia in the rat. J Nutr 1957;63:273-88.
11. Jen KLC, Alexander M, Zhong S, Rose K, Lin PKH, Kasim SE. Lipid lowering effect of omega-3 fatty acids in genetically obese zucker rats. Nutr Res 1989;9:1217-28.
12. Kingsley TR, Snyder DL. Serum lipids in spontaneously hypertensive rats and Sprague-Dawley rats fed menhaden oil. Lipids 1988;23:564-7.
13. Kobatake Y, Kuroda K, Jinnouchi H, Nishida E, Innami S. Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet. J Nutr Sci Vitaminol (Tokyo) 1984;30:357-72.
14. Lakshman MR, Chirtel SJ, Chambers LL. Roles of ω3 fatty acids and chronic ethanol in the regulation of plasma and liver lipids and plasma apoproteins A1 and E in rats. J Nutr 1988;118:1299-303.
15. Otto DA, Tsai CE, Baltzell JK, Wooten JT. Apparent inhibition of hepatic triacylglycerol secretion, independent of synthesis, in high-fat fish oil-fed rats: role for insulin. Biochim Biophys Acta 1991;1082:37-48.
16. Otto DA, Baltzell JK, Wooten JT. Reduction in triacylglycerol levels by fish oil correlates with free fatty acid level in ad libitum fed rats. Lipids 1992;27:1013-7.
17. Roach PD, Dowling K, Balasubramaniam S, et al. Fish oil and oat bran in combination effectively lower plasma cholesterol in rat. Atherosclerosis 1992;96:219-26.
18. Rogers KA, Karnovsky MJ. Dietary fish oil enhances monocyte adhesion and fatty streak formation in the hypercholesterolemic rat. Am J Pathol 1988;132:382-8.
19. Rustan AC, Hustvedt BE, Drevon CA. Dietary supplementation of very long chain n-3 fatty acids decreases whole body lipid utilization in the rat. J Lipid Res 1993;34:1299-309.
20. Sebokova E, Klimes I, Hermann M, et al. Fish oil modifies lipid composition and liver LDL receptor activity in hypertriglyceridemic rats. Diabetes Nutr Metab 1992;5:249-57.
21. Shimamura T, Wilson AC. Influence of dietary fish oil on the aortic, myocardial and renal lesions of SHR. J Nutr Sci Vitaminol (Tokyo) 1991;37:581-90.
22. Tripodi A, Loria P, Dilengite MA, Carulli N. Effect of fish oil and coconut oil diet on the LDL receptor activity of rat liver plasma membranes. Biochim Biophys Acta 1991;1083:298-304.
23. Ventura MA, Woollett LA, Spady DK. Dietary fish oil stimulates hepatic low density lipoprotein transport in the rat. J Clin Invest 1989;84:528-37.
24. Willumsen N, Hexeberg S, Skorve J, Lundquist M, Berge RK. Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats. J Lipid Res 1993;34:13-22.
25. Adelstein R, Ferguson LD, Rogers KA. Effects of dietary n-3 fatty acid supplementation on lipoproteins and intimai foam cell accumulation in the casein-fed rabbit. Clin Invest Med 1992;15:71-81.
26. Bolton-Smith C, Gibney MJ, Gallagher PJ, Jewell R, Hillier K. Effect of polyunsaturated fatty acids of the n-3 and n-6 series on lipid composition and eicosanoid synthesis of platelets and aorta and on immunological induction of atherosclerosis in rabbits. Atherosclerosis 1988;72:29-35.
27. Campos CT, Michalek VN, Matts JP, Buchwald H. Dietary marine oil supplements fail to affect cholesterol metabolism or inhibit atherosclerosis in rabbits with diet-induced hypercholesterolemia. Surgery 1989;106:177-84.
28. Chen MF, Lee YT, Hsu HC, Yeh PC, Liau CS, Huang PC. Effects of dietary supplementation with fish oil on atherosclerosis and myocardial injury during acute coronary occlusion-reperfusion in diet-induced hypercholesterolemic rabbits. Int J Cardiol 1992;35:323-31.
29. Clubb FJJ, Schmitz JM, Butler MM, Buja LM, Willerson JT, Campbell WB. Effect of dietary omega-3 fatty acid on serum lipids, platelet function, and atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Arteriosclerosis 1989;9:529-37.
30. Demiroglu C, Ozder A, Altug T, et al. Suppression of atherogenesis by n-3 fatty acids in the cholesterol-fed rabbit. Angiology 1991;42:323-30.
31. Kristensen SD, Roberts KM, Lawry J, Martin JF. The effect of fish oil on atherogenesis and thrombopoiesis in rabbits on high cholesterol diet. Artery 1988;15:250-8.
32. Lichtenstein AH, Chobanian AV. Effect of fish oil on atherogenesis in Watanabe heritable hyperlipidemic rabbit. Arteriosclerosis 1990;10:597-606.
33. Loo G, Berlin E, Peters RC, Kliman PG, Wong HYC. Effect of dietary corn, coconut, and menhaden oils on lipoprotein, liver, and heart membrane composition in the hypercholesterolemic rabbit. J Nutr Biochem 1991;2:594-603.
34. Nelson GJ, Kelley DS, Schmidt PC, Serrato CM, Lindgren FT. Effect of menhaden oil and various seed oils on serum lipids and lipoproteins in rabbits. Nutr Res 1989;9:531-44.
35. Rich S, Miller JF, Charous S, et al. Development of atherosclerosis in genetically hyperlipidemic rabbits during chronic fish-oil ingestion. Arteriosclerosis 1989;9:189-94.
36. Rogers KA, Adelstein R. MaxEPA fish oil enhances cholesterol-induced intimal foam cell formation in rabbits. Am J Pathol 1990;137:945-51.
37. Samman S. The effect of Max EPA on low density lipoprotein metabolism: perspectives from an animal model. Prostaglandins Leukot Essent Fatty Acids 1991;43:83-5.
38. Thiery J, Seidel D. Fish oil feeding results in an enhancement of cholesterol-induced atherosclerosis in rabbits. Atherosclerosis 1987;63:53-6.
39. Yamaguchi K, Mizota M, Hashizume H, Kumagai A. Antiatherogenic action of eicosapentaenoic acid (EPA) in multiple oral doses. Prostaglandins Leukot Med 1987;28:35-43.
40. Yun KL, Fann JI, Sokoloff MH, et al. Dose response of fish oil versus safflower oil on graft arteriosclerosis in rabbit heterotopic cardiac allografts. Ann Surg 1991;214:155-67.
41. Zhu BQ, Smith DL, Sievers RE, Isenberg WM, Parmley WW. Inhibition of atherosclerosis by fish oil in cholesterol-fed rabbits. J Am Coll Cardiol 1988;12:1073-8.
42. Cahill PD, Sarris GE, Cooper AD, et al. Inhibition of vein graft intimal thickening by eicosapentaenoic acid: reduced thromboxane production without change in lipoprotein levels or low-density lipoprotein receptor density. J Vasc Surg 1988;7:108-18.
43. Casali RE, Hale JA, LeNarz L, Faas F, Morris MD. Improved graft patency associated with altered platelet function induced by marine fatty acids in dogs. J Surg Res 1986;40:6-12.
44. Landymore RW, Kinley CE, Cooper JH, MacAulay M, Sheridan B, Cameron C. Cod-liver oil in the prevention of intimal hyperplasia in autogenous vein grafts used for arterial bypass. J Thorac Cardiovasc Surg 1985;89:351-7.
45. Otsuji S, Shibata N, Hirota H, Akagami, H, Wada A. Highly purified eicosapentaenoic acid attenuates tissue damage in experimental myocardial infarction. Jpn Circ J 1993;57:335-43.
46. Foxall TL, Shwaery GT. Effects of dietary fish oil and butterfat on serum lipids and monocyte and platelet interactions with aortic endothelial cells. Atherosclerosis 1990;80:171-9.
47. Groot PHE, Scheek LM, Dubelaar ML, Verdouw PD, Hartog JM, Lamers JMJ. Effects of diets supplemented with lard fat or mackerel oil on plasma lipoprotein lipid concentrations and lipoprotein lipase activities in domestic swine. Atherosclerosis 1989;77:1-6.
48. Hartog JM, Lamers JMJ, Montfoort A, et al. Comparison of mackerel-oil and lard-fat enriched diets on plasma lipids, cardiac membrane phospholipids, cardiovascular performance, and morphology in young pigs. Am J Clin Nutr 1987;46:258-66.
49. Hartog JM, Lamers JMJ, Essed CE, Schalkwijk WP, Verdouw PD. Does platelet aggregation play a role in the reduction in localized intimal proliferation in normolipidemic pigs with fixed coronary artery stenosis fed dietary fish oil? Atherosclerosis 1989;76:79-88.
50. Huff MW, Telford DE. Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein. Arteriosclerosis 1989;9:58-66.
51. Huff MW, Telford DE, Edmonds BW, McDonald CG, Evans AJ. Lipoprotein lipases, lipoprotein density gradient profile and LDL receptor activity in miniature pigs fed fish oil and corn oil. Biochim Biophys Acta 1993;1210:113-22.
52. Kim DN, Ho HT, Lawrence DA, Schmee J, Thomas WA. Modification of lipoprotein patterns and retardation of atherogenesis by a fish oil supplement to a hyperlipidemic diet for swine. Atherosclerosis 1989;76:35-54.
53. Kim DN, Schmee J, Baker JE, et al. Dietary fish oil reduces microthrombi over atherosclerotic lesions in hyperlipidemic swine even in the absence of plasma cholesterol reduction. Exp Mol Pathol 1993;59:122-35.
54. Sassen LMA, Lamers JMJ, Sluiter W, et al. Development and regression of atherosclerosis in pigs. Arterioscler Thromb 1993;13:651-60.
55. Weiner BH, Ockene IS, Levine PH, et al. Inhibition of atherosclerosis by cod-liver oil in a hyperlipidemic swine model. N Engl J Med 1986;315:841-6.
56. Abbey M, Clifton PM, McMurchie EJ, McIntosh GH, Nestel PJ. Effect of a high fat/cholesterol diet with or without eicosapentaenoic acid on plasma lipids, lipoproteins and lipid transfer protein activity in the marmoset. Atherosclerosis 1990;81:163-74.
57. Davis HR, Bridenstine RT, Vesselinovitch D, Wissler RW. Fish oil inhibits development of atherosclerosis in rhesus monkeys. Arteriosclerosis 1987;7:441-9.
58. Parks JS, Wilson MD, Johnson FL, Rudel LL. Fish oil decreases hepatic cholesteryl ester secretion but not apoB secretion in African green monkeys. J Lipid Res 1989;30:1535-44.
59. Parks JS, Kaduck-Sawyer J, Bullock BC, Rudel LL. Effect of dietary fish oil on coronary artery and aortic atherosclerosis in African green monkeys. Arteriosclerosis 1990;10:1102-12.
60. Parks JS, Gebre AK. Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys. J Lipid Res 1991;32:305-15.
61. Smuts CM, Kruger M, van Jaarsveld PJ, et al. The influence of fish oil supplementation on plasma lipoproteins and arterial lipids in vervet monkeys with established atherosclerosis. Prostaglandins Leukot Essent Fatty Acids 1992;47:129-38.
62. Ward MV, Clarkson TB. The effect of a menhaden oil-containing diet on hemostatic and lipid parameters of nonhuman primates with atherosclerosis. Atherosclerosis 1985;57:325-35.