Cannabinoids enhance NMDA-elicited Ca2+ signals in cerebellar granule neurons in culture

Journal of Neuroscience

Volumn 19, Issue 20, 1999, Pages 8765-8777

  Netzeband, Jeffrey G ^a   Conroy, Shannon M ^a   Parsons, Kathy L ^a   Gruol, Donna L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cannabinoid; Cerebellum; Granule neuron; HU 210; Intracellular calcium; Methanandamide; NMDA; WIN

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM; CALCIUM CHANNEL; CANNABINOID; CANNABINOID RECEPTOR; DEXANABINOL; METHADONE; METHANANDAMIDE; N METHYL DEXTRO ASPARTIC ACID; PERTUSSIS TOXIN; PHOSPHOLIPASE C INHIBITOR; RIMONABANT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ACTIVATION; CELL MEMBRANE POTENTIAL; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SECOND MESSENGER;

EID: 0033570361     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-20-08765.1999     Document Type: Article

References (51)

1. Abadji V, Lin S, Taha G, Griffin G, Stevenson LA, Pertwee RG, Makriyannis A (1994) R-Methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability. J Med Chem 37:1889-1893.
2. Adams IB, Martin BR (1996) Cannabis: pharmacology and toxicology in animals and humans. Addiction 91:1585-1614.
3. Beani L, Tomasini C, Govoni BM, Bianchi C (1994) Fluorimetric determination of electrically evoked increase in intracellular calcium in cultured cerebellar granule cells. J Neurosci Methods 51:1-7.
4. 3) receptor. J Membr Biol 145:205-216.
5. Caulfield MP, Brown DA (1992) Cannabincid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. Br J Pharmacol 106:231-232.
6. Childers SR, Sexton T, Roy MB (1994) Effects of anandamide on cannabinoid receptors in rat brain membrines. Biochem Pharmacol 47:711-715.
7. Courtney MJ, Lambert JJ, Nicholls DG (1990) The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium n cultured ccrebcllar granule cells. J Neurosci 10:3873-3879.
8. Deadwylcr SA, Hampson RE, Bennett BA, Edwards TA, Mu J, Pacheco MA, Ward SJ. Childers SR (1993) Cannabinoids modulate potassium current in cultured hippocampal neurons, Receptors Channels 1:121-134.
9. Di Marzo V (1998) "Endocannabinoids" and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. Biochim Biophys Acta 1392:153-175.
10. Exton JH (1996) Regulation of phosphoinos tide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36:481-509.
11. Felder CC, Briley EM, Axclrod J, Simpson JT, Mackie K, Devane WA (1993) Anandamide. an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc Natl Atad Sci USA 90:7656-7660.
12. 2+], increases partly sensitive to capacitative store refilling. Eur J Pharmacol 336:R1-R3.
13. Garcia DE, Brown S, Hille B, Mackic K (1998) Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. J Neurosci 18:2834-2841.
14. Garthwaite G, Yamini Jr B, Garthwaite J (1987) Selective loss of Purkinje and granule cell responsivcncss to N-mcthyl-D-aspartatc in rat cerebellum during development. Dev Brain Res 36:288-292.
15. Gruol DL, Franklin CL (1987) Morphological and physiological differentiation of Purkinje neurons in cultures ol rat cerebellum. J Neurosci 7:1271-1293.
16. 2+ indicators with greatly improved fluorescerce properties. J Biol Chem 260:3440-3450.
17. Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ, Bickler PE (1998) Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J Neurochem 70:671-676.
18. Hell JW, Westenbroek RE, Warner C, Anlijanian MK, Prystay W, Gilbert MM, Snutch TP, Catterall WA (1993) Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel al subunits. J Cel Biol 123:949-962.
19. Henry DJ, Chavkin C (1995) Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat bra n cannabinoid receptors in Xenopus oocytes. Neurosci Lett 186:91-94.
20. Howlett AC, Champion-Dorow TM, McMahcn LL, Westlake TM (1991) The cannabinoid receptor: biochemical and cellular properties in neuroblastoma cells. Pharmacol Biochem Behav 40:565-569.
21. Hsieh C, Brown S, Derieth C, Mackic K (1999) Internalization and recycling of the CB1 receptor. J Neurochem 73:493-501.
22. Jin W, Lee NM, Loh HH, Thayer SA (1994) Opioids mobilize calcium from inositol 1,4,5-trisphosphatc-sensitivc stores in NG108-15 cells. J Neurosci 14:1920-1929.
23. Ĺvénès C, Daniel H, Soubrié P, Crépel F (1998) Cannabinoids decrease excitatory synaptic transmission and impair long-term depression in rat cercbellar Purkinje cells. J Physiol (Lond) 510:867-879.
24. Mackic K, Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89:3825-3829.
25. Mackie K, Lai Y, Westenbroek R, Mitchel R (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfectcd with rat brain cannabinoid receptor. J Neurosci 15:6552-6561.
26. Mailleux P, Vanderhaeghen J-J (1992) Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience 48:655-668.
27. Martin BR, Welch SP, Abood ME (1994) Progress toward understanding the cannabinoid receptor and its second messenger systems. Adv Pharmacol 25:341-397.
28. Matsuda LA. Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannahinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
29. Matsuda LA, Bonner TI, Lolait SJ (1993) Localization of cannabinoid receptor mRNA in rat brain. J Comp Neurol 327:535-550.
30. Mcrmelstcin PG, Decker JB, Surmeier DJ (1996) Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor. J Neurosci 16:595-604.
31. Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12:529-540.
32. Mori H, Mishina M (1995) Structure and function of the NMDA receptor channel. Neuropharmacology 34:1219-1237.
33. 2+ levels via the phospholipase C transduction pathway in cultured Purkinje neurons. J Neurophysiol 78:63-75.
34. Nogueron MI, Porgilsson B, Hillard CJ (1998) Characterisation of cannabinoids inhibition of calcium entry on cultured rat cerebcllar granule cells. FASEB J 12:A152.
35. Pacheco M, Childers SR, Arnold R, Casiano F, Ward SJ (1991) Aminoalkylindoles: actions on specific G-protein-linked receptors. J Pharmacol Exp Ther 257:170-183.
36. Pacheco MA, Ward SJ, Childers SR (1993) Identification of cannabinoid receptors in cultures of rat cerebcllar granule cells. Brain Res 603:102-110.
37. Pacheco MA, Ward SJ, Childers SR (1994) Differential requirements of sodium for coupling of cannabinoid receptors to adcnylyl cyclase in rat brain membranes. J Neurochem 62:1773-1782.
38. 2+ channels in a neuronal expression system. Mol Pharmacol 49:707-714.
39. Pertwee RG (1997) Pharmacology of cannabinoid CB, and CB, receptors. Pharmacol Ther 74:129-180.
40. Qiu Z, Parsons KL, Gruol DL (1995) Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons. J Neurosci 15:6688-6699.
41. Qiu Z, Sweeney DD, Netzeband JG, Gruol DL (1998) Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons. J Neurosci 18:10445-10456.
42. Romern J, Garcia-Palomero E, Berrendero F, Garcia-Gil L, Hernandez ML, Ramos JA, Fernandez-Ruiz JJ (1997) Atypical location of cannabinoid receptors in white matter areas during rat brain development. Synapse 26:317-323.
43. Shen M, Thayer SA (1998) The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons. Brain Res 783:77-84.
44. Shen M, Riser TM, Seybold VS, Thayer SA (1996) Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J Neurosci 16:4322-4334.
45. 2+ stores: activation and function. Trends Neurosci 18:299-306.
46. + currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proc Natl Acad Sci USA 94:12210-12217.
47. 2+ in neuroblastoma × glioma hybrid NG108-15 cells. Biochem Biophys Res Commun 229:58-64.
48. 2+ transient in NG108-15 cells. J Biochem 122:890-895.
49. Trenkner E (1991) Cerebellar cells in culture. In: Culturing nerve cells (Banker G, Goslin K, cds), pp 283-307. Cambridge, MA: MIT.
50. Tsou K, Brown S, Sañudo-Peña MC, Mackie K, Walker JM (1998) Immunohistochcmical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411.
51. Twitchell W, Brown S, Mackie K (1997) Cannabinoids inhibit N- and P/Q-typc calcium channels in cultured rat hippocampal neurons. J Neurophysiol 78:43-50.