Formation of transient covalent protein and DNA adducts by quercetin in cells with and without oxidative enzyme activity

Chemical Research in Toxicology

Volumn 18, Issue 12, 2005, Pages 1907-1916

  Van Der Woude, Hester ^a   Alink, Gerrit M ^a   Van Rossum, Bart E J ^a   Walle, Kristina ^b   Van Steeg, Harry ^c   Walle, Thomas ^b   Rietjens, Ivonne M C M ^a,d  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d TNO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLUTATHIONE; MONOPHENOL MONOOXYGENASE; MUTAGENIC AGENT; OXIDOREDUCTASE; PEROXIDASE; PROTEIN; QUERCETIN;

ARTICLE; BIOLOGICAL ACTIVITY; CARCINOGENICITY; CELL LEVEL; COMPLEX FORMATION; COVALENT BOND; DEPURINATED SITE; DNA ADDUCT; DNA STRUCTURE; ENZYME ACTIVITY; EXCISION REPAIR; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; MODEL; MOLECULAR STABILITY; MUTAGEN TESTING; OXIDATION; PROOXIDANT ACTIVITY; PROTEIN ADDUCT;

ANIMALS; CELL LINE; CELL LINE, TUMOR; DNA ADDUCTS; ENZYME ACTIVATION; GLUTATHIONE; HUMANS; MICE; MOLECULAR STRUCTURE; MONOPHENOL MONOOXYGENASE; OXIDATION-REDUCTION; PEROXIDASE; PROTEINS; QUERCETIN; TIME FACTORS;

EID: 29644439608     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050201m     Document Type: Article

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