Tyrosinase enhances the covalent modification of DNA by dopamine

Molecular Brain Research

Volumn 42, Issue 1, 1996, Pages 167-170

  Stokes, Alan H ^a   Brown, Buddy G ^b   Lee, Chin K ^b   Doolittle, David J ^a,b   Vrana, Kent E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b RJ Reynolds Tobacco Co   (United States)

Author keywords

DNA damage; Dopamine; Parkinson's disease; Tyrosinase

Indexed keywords

CATECHOLAMINE; DNA; DOPAMINE; FREE RADICAL; MONOPHENOL MONOOXYGENASE; PHOSPHORUS 32; TRITIUM;

ARTICLE; AUTOOXIDATION; CONTROLLED STUDY; DNA ADDUCT; DNA MODIFICATION; ISOTOPE LABELING; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY;

TRITIUM;

EID: 0030297648     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00164-7     Document Type: Article

References (21)

1. [1] Barden, H., Aviles, F. and Rivers, W., Interference filter microfluorametry and quantitation of fluorescence of neuromelanin and lipofuscin aged pigments in human brain. In S.N. Klaus (Eds.), Biological Basis of Pigmentation, Karger, Basel, 1979, pp. 263-269.
2. [2] Costa, C., Bertazzo, A., Allegri, G., Toffano, G., Curcuruto, O. and Traldi, P., Melanin biosynthesis from dopamine. II. A mass spectrometric and collisional spectroscopic investigation, Pigment Cell Res., 5 (1992) 122-131.
3. [3] Eling, T.E., Thompson, D.C., Foureman, G.L., Curtis, J.F. and Hughes, M.F., Prostaglandin H synthase and xenobiotic oxidation, Annu. Rev. Pharmacol. Toxicol., 30 (1990) 1-45.
4. [4] Foley, J.M. and Baxter, D., On the nature of pigment granule in the cells of the locus coeruleus and substantia nigra, J. Neuropathol Exp. Neurol., 17 (1958) 586-589.
5. [5] Garai, J., Tiller, A.A. and Clark, J.H., Tyrosinase-like polypeptides in the uterus and in the central nervous system of rats, Steroids, 57 (1992) 183-188.
6. [6] Graham, D.G., Tiffany, S.M., Bell, W.R. Jr. and Gutknecht, W.F., Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro, Mol. Pharmacol., 14 (1978) 644-653.
7. [7] Graham, D.G., Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones, Mol. Pharmacol., 14 (1978) 633-643.
8. 3H]dopamine: impact of ascorbic acid and glutathione, J. Neurochem., 63 (1994) 1126-1132.
9. [9] Hastings, T.G., Enzymatic oxidation of dopamine: the role of prostaglandin H syntbase, J. Neurochem., 64 (1995) 919-924.
10. [10] Hirsch, E.C., Graybiel, A.M. and Agid, Y., Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease, Nature, 334 (1988) 345-348.
11. [11] Kastner, A., Hirsch, E.C., Lejeune, O., Javoy-Agid, F., Rascol, O. and Agid, Y., Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content? J. Neurochem., 59 (1992) 1080-1089.
12. [12] King, R.A. and Witkop, C.J. Jr., Hairbulb tyrosinase activity in oculocutaneus albinism, Nature, 263 (1976) 69-71.
13. 32P-postlabeling assay of DNA adducts, Anal. Biochem., 227 (1995) 166-161.
14. [14] Levay, G. and Bodell, W.J., Detection of dopamine-DNA adducts: potential role in Parkinson's disease, Carcinogenesis, 14 (1993) 1241-1245.
15. [15] Mann, D.M.A. and Yates, P.O., Possible role of neuromelanin in the pathogenesis of Parkinson's disease, Mech. Aging Dev., 21 (1983) 193-203.
16. [16] Marsden, C.D., Brain melanin. In M. Wolman (Ed.), Pigment Pathology, Academic Press, New York, 1969, pp. 395-420.
17. [17] Michel, P.P. and Hefti, F., Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture, J. Neurosci. Res., 26 (1990) 428-435.
18. [18] Miranda, M., Botti, D., Bonfigli, A., Ventura, T. and Arcadi, A., Tyrosinase-like activity in normal human substantia nigra, Gen. Pharmacol., 15 (1984) 541-544.
19. [19] Moldeus, P., Nordenskjold, M., Bolcsfoldi, G., Eiche, A., Haglund, U. and Lambert, B., Genetic toxicity of dopamine, Mut. Res., 124 (1983) 9-24.
20. [20] Rodgers, A.D. and Curzon, G., Melanin formation by human brain in vitro, J. Neurochem., 24 (1975) 1123-1129.
21. [21] Rodriquez-Lopez, J.N., Varon, R. and Garcia-Canovas, F., Oxidation of 6-hydroxydopamine catalyzed by tyrosinase, Int. J. Biochem., 25 (1993) 1175-1182.