Inhibition of nitric oxide and caspase-3 mediated apoptosis by a tetrapeptide derivative (PEP1261) in cultured synovial fibroblasts from collagen-induced arthritis

Molecular and Cellular Biochemistry

Volumn 282, Issue 1-2, 2006, Pages 125-139

  Kumar, Dilly Ashok ^a   Settu, K ^a   Narayana Raju, Kalidindi V S ^b   Kumanan, K ^b   Manohar, Bhakthavatchalam Murali ^b   Puvanakrishnan, Rengarajulu ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^b MADRAS VETERINARY COLLEGE   (India)

Author keywords

Apoptosis; Collagen induced arthritis; Nitricoxide; Peptides; Synovial fibroblasts

Indexed keywords

ARGININE DERIVATIVE; ASPARAGINE DERIVATIVE; CASPASE 1 INHIBITOR; CASPASE 2 INHIBITOR; CASPASE 3; CASPASE 3 INHIBITOR; COLLAGEN; CYSTEINE PROTEINASE INHIBITOR; DNA FRAGMENT; LIPOCORTIN 5; N ACETYL S NITROSOPENICILLAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE DONOR; PEPTIDE DERIVATIVE; PROPIDIUM IODIDE; SERINE DERIVATIVE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME SUBSTRATE; FIBROBLAST; FLOW CYTOMETRY; INTRACELLULAR SPACE; MALE; NONHUMAN; RAT; RHEUMATOID ARTHRITIS; SYNOVIUM; WESTERN BLOTTING;

ANIMALS; ANNEXIN A5; APOPTOSIS; ARTHRITIS; CASPASE 3; CASPASES; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE II; ENZYME ACTIVATION; FIBROBLASTS; LACTOFERRIN; MALE; NITRIC OXIDE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; RATS; RATS, WISTAR; SYNOVIAL FLUID;

ANIMALIA;

EID: 29644438946     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-1737-4     Document Type: Article

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