Nitric oxide protects cultured rheumatoid synovial cells from Fas-induced apoptosis by inhibiting caspase-3

Immunology

Volumn 103, Issue 3, 2001, Pages 362-367

  Migita, Kiyoshi ^a   Yamasaki, Satoshi ^a   Kita, Masako ^a   Ida, Hiroaki ^a   Shibatomi, Kazutaka ^a   Kawakami, Atsushi ^a   Aoyagi, Takahiko ^b   Eguchi, Katsuni ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b Ureshino Medical Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CASPASE 3; CASPASE 8; FAS LIGAND; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE;

ANTIGENS, CD95; APOPTOSIS; ARTHRITIS, RHEUMATOID; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL CULTURE TECHNIQUES; ENZYME ACTIVATION; HUMANS; NITRIC OXIDE; NITRIC OXIDE DONORS; PENICILLAMINE; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE;

EID: 0034938198     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2001.01252.x     Document Type: Article

References (32)

1. Programmed cell death in animal development
2. Size control: The regulation of cell numbers in animal development
3. Mature T-lymphocyte apoptosis: Immune regulation is a dynamic and unpredictable antigenic environment
4. Anchorage-independent growth of synoviocytes from arthritic and normal joints
5. Hypothesis: In vitro evidence for the invasive and tumor-like properties of rheumatoid pannus
6. Apoptosis and functional Fas antigen in rheumatoid arthritis synoviocytes
7. Apoptosis in rheumatoid arthritis synovium
8. Apoptosis in rheumatoid arthritis
9. Apoptosis by death factor
10. FADD, a novel death domain containing protein, interacts with the death domain of Fas and initiates apoptosis
11. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
12. FLICE, a novel FADD-homologous ICE/CED-3 like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
13. An induced proximity model for caspase-8 activation
14. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
15. Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients
16. Nitric oxide as S-nitrosoproteins in rheumatoid arthritis
17. Chondrocyte apoptosis induced by nitric oxide
18. Nitric oxide induces apoptosis in mouse thymocytes
19. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
20. Nitric oxide inhibits Fas-induced apoptosis
21. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1 beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases
22. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression of early apoptotic cells using fluorescein labelled Annexin V
23. Bid, a Bc12 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
24. Apoptosis in the pathogenesis and treatment of disease
25. Nitric oxide: A physiologic messenger molecule
26. Elevated nitric oxide production in rheumatoid arthritis
27. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides
28. Nitric oxide reversibly inhibits seven members of caspase family via S-nitrosylation
29. Nitric oxide inhibits caspase-3 by S-nitrosylation in vivo
30. Cleavage of Bid by caspase-8 mediates the mitochondrial damage in the Fas pathway of apoptosis
31. Fas-induced caspase denitrosylation
32. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation