Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

Oncogene

Volumn 18, Issue 15, 1999, Pages 2461-2470

  Kim, Young Bae ^a   Lee, Kun Hyung ^a   Sugita, Kenji ^b   Yoshida, Minuro ^a   Horinouchi, Sueharu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

Author keywords

Antitumor; Cell cycle; Histone acetylation; p21(WAF1 cip1)

Indexed keywords

ANTINEOPLASTIC AGENT; BUTYRIC ACID; CYCLIN A; CYCLIN D1; CYCLIN E; FR 901228; GELSOLIN; HISTONE; HISTONE DEACETYLASE; OXAMFLATIN; PROTEIN P21; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOSE RESPONSE; ENZYME INHIBITION; GENE EXPRESSION; HELA CELL; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CDC2-CDC28 KINASES; CELL DIVISION; CYCLIN A; CYCLIN D1; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; CYTOMEGALOVIRUS; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FEMALE; GELSOLIN; GENE EXPRESSION REGULATION; HELA CELLS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; MAMMALS; MELANOMA, EXPERIMENTAL; MICE; PERITONEAL NEOPLASMS; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; UP-REGULATION;

ANIMALIA; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; MAMMALIA;

EID: 0033561497     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202564     Document Type: Article

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