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Volumn 13, Issue 5, 2004, Pages 353-358

Gene therapy in systemic lupus erythematosus

Author keywords

All therapy; Cytokines; Gene therapy; Genetics; SLE

Indexed keywords

CYTOKINE;

EID: 2942716916     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1191/0961203304lu1026oa     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 2942710089 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Theofilopoulos A, Bona C eds. Gordon and Breach, Harwood Academic Publishers
    • Tsokos GC, Boumpas DT. Systemic lupus erythematosus. In Theofilopoulos A, Bona C eds. Molecular pathology of autoimmunity. Gordon and Breach, Harwood Academic Publishers, 2001: 255-281.
    • (2001) Molecular Pathology of Autoimmunity , pp. 255-281
    • Tsokos, G.C.1    Boumpas, D.T.2
  • 2
    • 0033755567 scopus 로고    scopus 로고
    • Molecular aberrations in human lupus
    • Kammer GM, Tsokos GC. Molecular aberrations in human lupus. Mol Med Today 2000; 6: 418-424.
    • (2000) Mol Med Today , vol.6 , pp. 418-424
    • Kammer, G.M.1    Tsokos, G.C.2
  • 3
    • 0035849176 scopus 로고    scopus 로고
    • Advances in immunology: Complement, second of two parts
    • Mackay I, Rosen F. Advances in immunology: complement, second of two parts. N Engl J Med 2001; 344: 1140-1144.
    • (2001) N Engl J Med , vol.344 , pp. 1140-1144
    • Mackay, I.1    Rosen, F.2
  • 4
    • 0021611957 scopus 로고
    • Systemic lupus erythematosus: Current state of the genetic hypothesis
    • Arnett FC, Reveille JD, Wilson RW et al. Systemic lupus erythematosus: current state of the genetic hypothesis. Semin Arthritis Rheum 1984; 14: 24-35.
    • (1984) Semin Arthritis Rheum , vol.14 , pp. 24-35
    • Arnett, F.C.1    Reveille, J.D.2    Wilson, R.W.3
  • 5
    • 0032725422 scopus 로고    scopus 로고
    • The role of sex hormones in systemic lupus erythematosus
    • Lahita RG. The role of sex hormones in systemic lupus erythematosus. Curr Opin Rheumatol 1999; 11: 352-356.
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 352-356
    • Lahita, R.G.1
  • 6
    • 0026537198 scopus 로고
    • A revised estimate of twin concordance in systemic lupus erythematosus
    • Deapen D, Escalante A, Weinrib L et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 1992; 35: 311-318.
    • (1992) Arthritis Rheum , vol.35 , pp. 311-318
    • Deapen, D.1    Escalante, A.2    Weinrib, L.3
  • 7
    • 0242302583 scopus 로고    scopus 로고
    • The genetics of human systemic lupus erythematosus
    • Tsao BP. The genetics of human systemic lupus erythematosus. Trends Immunol 2003; 24: 595-602.
    • (2003) Trends Immunol , vol.24 , pp. 595-602
    • Tsao, B.P.1
  • 8
    • 0037668666 scopus 로고    scopus 로고
    • Uncovering the genetics of systemic lupus erythematosus
    • Kyttaris VC, Tsokos GC. Uncovering the genetics of systemic lupus erythematosus. Am J Pharmacso 2003; 3: 193-202.
    • (2003) Am J Pharmacso , vol.3 , pp. 193-202
    • Kyttaris, V.C.1    Tsokos, G.C.2
  • 9
    • 0038004857 scopus 로고    scopus 로고
    • Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: An international meta-analysis
    • Karassa FB, Bijl M, Davies KA et al. Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis. Arthritis Rheum 2003; 48: 1930-1938.
    • (2003) Arthritis Rheum , vol.48 , pp. 1930-1938
    • Karassa, F.B.1    Bijl, M.2    Davies, K.A.3
  • 10
    • 0029866721 scopus 로고    scopus 로고
    • Fc gamma RIIA alleles are heritable risk for SLE nephritis in African Americans
    • Salmon JE, Millard S, Schachter LA et al. Fc gamma RIIA alleles are heritable risk for SLE nephritis in African Americans. J Clin Invest 1996; 97: 1348-1354.
    • (1996) J Clin Invest , vol.97 , pp. 1348-1354
    • Salmon, J.E.1    Millard, S.2    Schachter, L.A.3
  • 11
    • 0036676085 scopus 로고    scopus 로고
    • Genetic linkage and association of Fcγr Receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus
    • Edberg JC, Langfeld CD, Wu J et al. Genetic linkage and association of Fcγr Receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2132-2140.
    • (2002) Arthritis Rheum , vol.46 , pp. 2132-2140
    • Edberg, J.C.1    Langfeld, C.D.2    Wu, J.3
  • 12
    • 0035046581 scopus 로고    scopus 로고
    • Human receptors of immunoglobulin G: Key elements in the pathogenesis of rheumatic disease
    • Salmon JE, Pricop L. Human receptors of immunoglobulin G: key elements in the pathogenesis of rheumatic disease. Arthritis Rheum 2001; 44: 739-750.
    • (2001) Arthritis Rheum , vol.44 , pp. 739-750
    • Salmon, J.E.1    Pricop, L.2
  • 13
    • 0028093373 scopus 로고
    • Hereditary C1q deficiency and systemic lupus erythematosus
    • Browness P, Davies KA, Norsworthy PJ et al. Hereditary C1q deficiency and systemic lupus erythematosus. QMJ 1994; 87: 455-464.
    • (1994) QMJ , vol.87 , pp. 455-464
    • Browness, P.1    Davies, K.A.2    Norsworthy, P.J.3
  • 15
    • 0033560931 scopus 로고    scopus 로고
    • PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus
    • Tsao BP, Cantor RM, Grossman M et al. PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus. J Clin Invest 1999; 103: 1135-1140.
    • (1999) J Clin Invest , vol.103 , pp. 1135-1140
    • Tsao, B.P.1    Cantor, R.M.2    Grossman, M.3
  • 16
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
    • Prokunina L, Castillejo-Lopez C, Oberg F et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nature Genetics 2002; 32: 666-669.
    • (2002) Nature Genetics , vol.32 , pp. 666-669
    • Prokunina, L.1    Castillejo-Lopez, C.2    Oberg, F.3
  • 18
    • 0033529049 scopus 로고    scopus 로고
    • Infliximab for the treatment of fistulas in patients with Crohn's disease
    • Present DH, Rutgeerts P, Targan S et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999; 340: 1398-1405.
    • (1999) N Engl J Med , vol.340 , pp. 1398-1405
    • Present, D.H.1    Rutgeerts, P.2    Targan, S.3
  • 20
    • 0038146960 scopus 로고    scopus 로고
    • Immunopathology and the gene therapy in lupus
    • Mageed RA, Prud'homme GJ. Immunopathology and the gene therapy in lupus. Gene Ther 2003; 10: 861-874.
    • (2003) Gene Ther , vol.10 , pp. 861-874
    • Mageed, R.A.1    Prud'homme, G.J.2
  • 21
    • 0029032871 scopus 로고
    • Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1 beta, interleukin-1 and interferon-gamma mRNA in the lymph nodes of lupus-prone mice
    • Prud'homme GJ, Kono DH, Theofilopoulos AN. Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1 beta, interleukin-1 and interferon-gamma mRNA in the lymph nodes of lupus-prone mice. Molec Immunol 1995; 32: 495-503.
    • (1995) Molec Immunol , vol.32 , pp. 495-503
    • Prud'homme, G.J.1    Kono, D.H.2    Theofilopoulos, A.N.3
  • 22
    • 0033020168 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein
    • Prud'homme GJ, Chang Y. Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein. Gene Ther 1999; 6: 771-777.
    • (1999) Gene Ther , vol.6 , pp. 771-777
    • Prud'homme, G.J.1    Chang, Y.2
  • 23
    • 0033222419 scopus 로고    scopus 로고
    • Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 fusion protein
    • Chang Y, Prud'homme GJ. Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 fusion protein. J Gene Med 1999; 1: 415-423.
    • (1999) J Gene Med , vol.1 , pp. 415-423
    • Chang, Y.1    Prud'homme, G.J.2
  • 24
    • 0033942181 scopus 로고    scopus 로고
    • Treatment of murine lupus with cDNA encoding IFN-[gamma]R/Fc
    • Lawson BR, Prud'homme GJ, Chang Y et al. Treatment of murine lupus with cDNA encoding IFN-[gamma]R/Fc. J Clin Inv 2000; 106: 207-215.
    • (2000) J Clin Inv , vol.106 , pp. 207-215
    • Lawson, B.R.1    Prud'homme, G.J.2    Chang, Y.3
  • 25
    • 0029021257 scopus 로고
    • Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery
    • Raz E, Dudler J, Lotz M et al. Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery. Lupus 1995; 4: 286-292.
    • (1995) Lupus , vol.4 , pp. 286-292
    • Raz, E.1    Dudler, J.2    Lotz, M.3
  • 26
    • 0033046191 scopus 로고    scopus 로고
    • Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF-beta1 gene therapy using attenuated Salmonella typhimurium as gene carrier
    • Huggins ML, Huang FP, Xu D, Lindop G, Stott DI. Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF-beta1 gene therapy using attenuated Salmonella typhimurium as gene carrier. Lupus 1999; 8: 29-38.
    • (1999) Lupus , vol.8 , pp. 29-38
    • Huggins, M.L.1    Huang, F.P.2    Xu, D.3    Lindop, G.4    Stott, D.I.5
  • 27
    • 0025289913 scopus 로고
    • Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus
    • Gutierrez-Ramos JC, Andreu JL, Revilla Y, Vinuela E, Martinez C. Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/ vaccinia recombinant virus. Nature 1990; 346: 271-274.
    • (1990) Nature , vol.346 , pp. 271-274
    • Gutierrez-Ramos, J.C.1    Andreu, J.L.2    Revilla, Y.3    Vinuela, E.4    Martinez, C.5
  • 28
    • 0029880442 scopus 로고    scopus 로고
    • The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice
    • Huang FP, Feng GJ, Lindop G, Strott DI, Liew FY. The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. J Exp Med 1996; 183: 1447-1459.
    • (1996) J Exp Med , vol.183 , pp. 1447-1459
    • Huang, F.P.1    Feng, G.J.2    Lindop, G.3    Strott, D.I.4    Liew, F.Y.5
  • 29
    • 18244422120 scopus 로고    scopus 로고
    • IL-12-encoding plasmid has a beneficial effect on spontaneous autoimmune disease in MRL/MP-lpr/lpr mice
    • Hagiwara E, Okubo T, Aoki I et al. IL-12-encoding plasmid has a beneficial effect on spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. Cytokine 2000; 12: 1035-1041.
    • (2000) Cytokine , vol.12 , pp. 1035-1041
    • Hagiwara, E.1    Okubo, T.2    Aoki, I.3
  • 30
    • 0035874769 scopus 로고    scopus 로고
    • Clear suppression of Th1 responses but marginal amelioration of autoimmune manifestations by IL-12p40 transgene in MRL-FAS(lprcg)/FAS(lprcg) mice
    • Yasuda T, Yoshimoto T, Tsubura A, Matsuzawa A. Clear suppression of Th1 responses but marginal amelioration of autoimmune manifestations by IL-12p40 transgene in MRL-FAS(lprcg)/FAS(lprcg) mice. Cell Immunol 2001; 210: 77-86.
    • (2001) Cell Immunol , vol.210 , pp. 77-86
    • Yasuda, T.1    Yoshimoto, T.2    Tsubura, A.3    Matsuzawa, A.4
  • 31
    • 0033976034 scopus 로고    scopus 로고
    • CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice
    • Takiguchi M, Murakami M, Nakagawa I, Salto I, Hashimoto A, Uede T. CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice. Life Sci 2000; 66: 991-1001.
    • (2000) Life Sci , vol.66 , pp. 991-1001
    • Takiguchi, M.1    Murakami, M.2    Nakagawa, I.3    Salto, I.4    Hashimoto, A.5    Uede, T.6
  • 32
    • 0033179001 scopus 로고    scopus 로고
    • Abnormal NF-kB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression
    • Wong HK, Kammer GM, Dennis G, Tsokos GC. Abnormal NF-kB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression. J Immunol 1999; 163: 1682-1689.
    • (1999) J Immunol , vol.163 , pp. 1682-1689
    • Wong, H.K.1    Kammer, G.M.2    Dennis, G.3    Tsokos, G.C.4
  • 33
    • 0036264363 scopus 로고    scopus 로고
    • Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity
    • Hemdon TM, Juang Y-T, Solomou EE, Rothwell SW, Gourley MF, Tsokos GC. Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity. Clin Immunol 2002; 103: 145-153.
    • (2002) Clin Immunol , vol.103 , pp. 145-153
    • Hemdon, T.M.1    Juang, Y.-T.2    Solomou, E.E.3    Rothwell, S.W.4    Gourley, M.F.5    Tsokos, G.C.6
  • 34
    • 0035869333 scopus 로고    scopus 로고
    • Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus
    • Solomou EE, Juang Y-T, Gourley MF, Kammer GM, Tsokos GC. Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus. J Immunol 2001; 166: 4216-4222.
    • (2001) J Immunol , vol.166 , pp. 4216-4222
    • Solomou, E.E.1    Juang, Y.-T.2    Gourley, M.F.3    Kammer, G.M.4    Tsokos, G.C.5
  • 35
    • 0037108487 scopus 로고    scopus 로고
    • Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus
    • Tenbrock K, Juang Y-T, Gourley MF, Nambiar MP, Tsokos GC. Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus. J Immunol 2002; 169: 4147-4152.
    • (2002) J Immunol , vol.169 , pp. 4147-4152
    • Tenbrock, K.1    Juang, Y.-T.2    Gourley, M.F.3    Nambiar, M.P.4    Tsokos, G.C.5
  • 36
    • 0036560022 scopus 로고    scopus 로고
    • Abnormal T cell signal transduction in systemic lupus erythematosus
    • Kammer GM, Perl A, Richardson BC, Tsokos GC. Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum 2002; 46: 1139-1154.
    • (2002) Arthritis Rheum , vol.46 , pp. 1139-1154
    • Kammer, G.M.1    Perl, A.2    Richardson, B.C.3    Tsokos, G.C.4
  • 37
    • 0038342830 scopus 로고    scopus 로고
    • Reconstitution of deficient T cell receptor æ chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus
    • Nambiar MP, Fisher CU, Warke VG et al. Reconstitution of deficient T cell receptor æ chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus. Arthritis Rheum 2003; 48: 1948-1955.
    • (2003) Arthritis Rheum , vol.48 , pp. 1948-1955
    • Nambiar, M.P.1    Fisher, C.U.2    Warke, V.G.3
  • 38
    • 0346969979 scopus 로고    scopus 로고
    • CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis
    • Liu Z, Xu X, Hsu HC et al. CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis. J Clin Inv 2003; 112: 1332-1341.
    • (2003) J Clin Inv , vol.112 , pp. 1332-1341
    • Liu, Z.1    Xu, X.2    Hsu, H.C.3
  • 39
    • 0034669953 scopus 로고    scopus 로고
    • Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells
    • El Amine M, Melo M, Kang Y, Nguyen H, Qian J, Scott DW. Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells. J Immunol 2000; 165: 5631-5636.
    • (2000) J Immunol , vol.165 , pp. 5631-5636
    • El Amine, M.1    Melo, M.2    Kang, Y.3    Nguyen, H.4    Qian, J.5    Scott, D.W.6
  • 40
    • 0031093505 scopus 로고    scopus 로고
    • Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients
    • Zambidis ET, Barth RK, Scott DW. Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients. J Immunol 1997; 158: 2174-2182.
    • (1997) J Immunol , vol.158 , pp. 2174-2182
    • Zambidis, E.T.1    Barth, R.K.2    Scott, D.W.3
  • 41
    • 0033927572 scopus 로고    scopus 로고
    • Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis
    • Agarwal RK, Kang Y, Zambidis E, Scott DW, Chan CC, Caspi RR. Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis. J Clin Invest 2000; 106: 245-252.
    • (2000) J Clin Invest , vol.106 , pp. 245-252
    • Agarwal, R.K.1    Kang, Y.2    Zambidis, E.3    Scott, D.W.4    Chan, C.C.5    Caspi, R.R.6
  • 42
    • 0036569428 scopus 로고    scopus 로고
    • Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases
    • Melo ME, Qian J, El Amine M et al. Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases. J Immunol 2002; 168: 4788-4795.
    • (2002) J Immunol , vol.168 , pp. 4788-4795
    • Melo, M.E.1    Qian, J.2    El Amine, M.3


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