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Volumn 3, Issue 3, 2003, Pages 193-202

Uncovering the genetics of systemic lupus erythematosus: Implications for therapy

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 2;

EID: 0037668666     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200303030-00005     Document Type: Review
Times cited : (9)

References (116)
  • 1
    • 84892356024 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Theofilopoulos A, Bona C, editors. New York: Taylor and Francis
    • Tsokos GC, Boumpas DT. Systemic lupus erythematosus. In: Theofilopoulos A, Bona C, editors. Molecular pathology of autoimmunity. 2nd ed. New York: Taylor and Francis, 2002: 261-87
    • (2002) Molecular Pathology of Autoimmunity. 2nd Ed. , pp. 261-287
    • Tsokos, G.C.1    Boumpas, D.T.2
  • 2
    • 0033755567 scopus 로고    scopus 로고
    • Molecular aberrations in human lupus
    • Kammer GM, Tsokos GC. Molecular aberrations in human lupus. Mol Med Today 2000; 6: 418-24
    • (2000) Mol Med Today , vol.6 , pp. 418-424
    • Kammer, G.M.1    Tsokos, G.C.2
  • 3
    • 0035849176 scopus 로고    scopus 로고
    • Advances in immunology: Complement, second of two parts
    • Mackay I, Rosen F. Advances in immunology: complement, second of two parts. N Engl J Med 2001; 344: 1140-4
    • (2001) N Engl J Med , vol.344 , pp. 1140-1144
    • Mackay, I.1    Rosen, F.2
  • 4
    • 0031968825 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States
    • Lawrence RC, Helmick CG, Arnett FC, et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 1998; 41: 778-99
    • (1998) Arthritis Rheum , vol.41 , pp. 778-799
    • Lawrence, R.C.1    Helmick, C.G.2    Arnett, F.C.3
  • 5
    • 0025372094 scopus 로고
    • Estimating the incidence of systemic lupus erythematosus in a defined population using multiple sources of retrieval
    • Jonsson H, Nived O, Sturfelt G, et al. Estimating the incidence of systemic lupus erythematosus in a defined population using multiple sources of retrieval. Br J Rheumatol 1990; 29: 185-8
    • (1990) Br J Rheumatol , vol.29 , pp. 185-188
    • Jonsson, H.1    Nived, O.2    Sturfelt, G.3
  • 6
    • 0029143904 scopus 로고
    • Incidence of systemic lupus erythematosus: Race and gender differences
    • McCarty DJ, Manzi S, Medsger Jr TA, et al. Incidence of systemic lupus erythematosus: race and gender differences. Arthritis Rheum 1995; 38: 1260-70
    • (1995) Arthritis Rheum , vol.38 , pp. 1260-1270
    • McCarty, D.J.1    Manzi, S.2    Medsger T.A., Jr.3
  • 7
    • 0032725422 scopus 로고    scopus 로고
    • The role of sex hormones in systemic lupus erythematosus
    • Lahita RG. The role of sex hormones in systemic lupus erythematosus. Curr Opin Rheumatol 1999; 11: 352-6
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 352-356
    • Lahita, R.G.1
  • 8
    • 0022006339 scopus 로고
    • The incidence of systemic lupus erythematosus in Baltimore, Maryland, 1970-1977
    • Hochberg MC. The incidence of systemic lupus erythematosus in Baltimore, Maryland, 1970-1977. Arthritis Rheum 1985; 28: 80-6
    • (1985) Arthritis Rheum , vol.28 , pp. 80-86
    • Hochberg, M.C.1
  • 9
    • 0025357195 scopus 로고
    • Clinical manifestations of systemic lupus erythematosus: Identification of racial and socioeconomic influences
    • Ward MM, Studenski S. Clinical manifestations of systemic lupus erythematosus: identification of racial and socioeconomic influences. Arch Intern Med 1990; 150: 849-53
    • (1990) Arch Intern Med , vol.150 , pp. 849-853
    • Ward, M.M.1    Studenski, S.2
  • 10
    • 0032895063 scopus 로고    scopus 로고
    • Trends in the incidence and mortality of systemic lupus erythematosus
    • Uramoto KM, Michet Jr CJ, Thumboo J, et al. Trends in the incidence and mortality of systemic lupus erythematosus. Arthritis Rheum 1999; 42: 46-50
    • (1999) Arthritis Rheum , vol.42 , pp. 46-50
    • Uramoto, K.M.1    Michet C.J., Jr.2    Thumboo, J.3
  • 11
    • 0027537389 scopus 로고
    • Systemic lupus erythematosus: Clinical and immunologic patterns of disease expression in a cohort of 1,000 patients
    • The European Working Party on Systemic Lupus Erythematosus
    • Cervera R, Khamashta MA, Font J, et al. Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients. The European Working Party on Systemic Lupus Erythematosus. Medicine (Baltimore) 1993; 72: 113-24
    • (1993) Medicine (Baltimore) , vol.72 , pp. 113-124
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3
  • 12
    • 0001957767 scopus 로고    scopus 로고
    • Pathogenesis of rheumatic diseases: Systemic lupus erythematosus
    • Tsokos GC, editor. Totowa (NJ): Humana Press
    • Liossis SN, Tsokos GC. Pathogenesis of rheumatic diseases: systemic lupus erythematosus. In: Tsokos GC, editor. Principles of molecular rheumatology. Totowa (NJ): Humana Press, 2000: 311-23
    • (2000) Principles of Molecular Rheumatology , pp. 311-323
    • Liossis, S.N.1    Tsokos, G.C.2
  • 13
    • 0021611957 scopus 로고
    • Systemic lupus erythematosus: Current state of the genetic hypothesis
    • Arnett FC, Reveille JD, Wilson RW, et al. Systemic lupus erythematosus: current state of the genetic hypothesis. Semin Arthritis Rheum 1984; 14: 24-35
    • (1984) Semin Arthritis Rheum , vol.14 , pp. 24-35
    • Arnett, F.C.1    Reveille, J.D.2    Wilson, R.W.3
  • 14
    • 0023427948 scopus 로고
    • A family survey of lupus erythematosus: Heritability
    • Lawrence JS, Martins CL, Drake GL. A family survey of lupus erythematosus: heritability. J Rheumatol 1987; 14: 913-21
    • (1987) J Rheumatol , vol.14 , pp. 913-921
    • Lawrence, J.S.1    Martins, C.L.2    Drake, G.L.3
  • 15
    • 0026537198 scopus 로고
    • A revised estimate of twin concordance in systemic lupus erythematosus
    • Dcapen D, Escalante A, Weinrib L, et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 1992; 35: 311-8
    • (1992) Arthritis Rheum , vol.35 , pp. 311-318
    • Dcapen, D.1    Escalante, A.2    Weinrib, L.3
  • 16
    • 0028913737 scopus 로고
    • Estrogens, the immune response and autoimmunity
    • Cutolo M, Sulli A, Seriolo B, et al. Estrogens, the immune response and autoimmunity. Clin Exp Rheumatol 1995; 13: 217-26
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 217-226
    • Cutolo, M.1    Sulli, A.2    Seriolo, B.3
  • 17
    • 0002790634 scopus 로고
    • Systemic lupus erythematosus and the skin
    • Lahita RG, editor. New York: Churchill and Livingstone
    • Sontheimer RD, Gilliam JN. Systemic lupus erythematosus and the skin. In: Lahita RG, editor. Systemic lupus erythematosus. New York: Churchill and Livingstone, 1992
    • (1992) Systemic Lupus Erythematosus
    • Sontheimer, R.D.1    Gilliam, J.N.2
  • 18
    • 0031695365 scopus 로고    scopus 로고
    • Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus
    • Cooper GS, Dooley MA, Treadwell EL, et al. Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus. Arthritis Rheum 1998; 41: 1714-24
    • (1998) Arthritis Rheum , vol.41 , pp. 1714-1724
    • Cooper, G.S.1    Dooley, M.A.2    Treadwell, E.L.3
  • 19
    • 0034760335 scopus 로고    scopus 로고
    • Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: A case-control study
    • Ghaussy NO, Sibbitt Jr WL, Qualls CR. Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: a case-control study. J Rheumatol 2001; 28: 2449-53
    • (2001) J Rheumatol , vol.28 , pp. 2449-2453
    • Ghaussy, N.O.1    Sibbitt W.L., Jr.2    Qualls, C.R.3
  • 20
    • 0031465706 scopus 로고    scopus 로고
    • An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus
    • James JA, Kaufman KM, Farris AD, et al. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 1997; 100: 3019-26
    • (1997) J Clin Invest , vol.100 , pp. 3019-3026
    • James, J.A.1    Kaufman, K.M.2    Farris, A.D.3
  • 21
    • 0003194176 scopus 로고    scopus 로고
    • T lymphocytes, natural killer cells, cytokines, and immune regulation
    • Wallace DJ, Hahn BH, editors. Baltimore (MD): Lippincott Williams and Wilkins
    • Horwitz DA, Stohl W, Gray JD. T lymphocytes, natural killer cells, cytokines, and immune regulation. In: Wallace DJ, Hahn BH, editors. Dubois' lupus erythematosus. Baltimore (MD): Lippincott Williams and Wilkins, 1997: 155-94
    • (1997) Dubois' Lupus Erythematosus , pp. 155-194
    • Horwitz, D.A.1    Stohl, W.2    Gray, J.D.3
  • 22
    • 0002895241 scopus 로고    scopus 로고
    • Overview of cellular immune function in systemic lupus erythematosus
    • Lahita RG, editor. New York: Academic Press
    • Tsokos GC. Overview of cellular immune function in systemic lupus erythematosus. In: Lahita RG, editor. Systemic lupus erythematosus. New York: Academic Press, 1999: 17-54
    • (1999) Systemic Lupus Erythematosus , pp. 17-54
    • Tsokos, G.C.1
  • 23
    • 0031267305 scopus 로고    scopus 로고
    • The immunoregulatory effects of NK cells: The role of TGF- and implications for autoimmunity
    • Horwitz DA, Gray JD, Ohtsuka K, et al. The immunoregulatory effects of NK cells: the role of TGF- and implications for autoimmunity. Immunol Today 1997; 18: 538-42
    • (1997) Immunol Today , vol.18 , pp. 538-542
    • Horwitz, D.A.1    Gray, J.D.2    Ohtsuka, K.3
  • 24
    • 0029910218 scopus 로고    scopus 로고
    • Impaired recovery and cytolytic function of CD56+ T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation: Studies in unselected patients and monozygotic disease-discordant twins
    • Stohl W, Elliott JE, Hamilton AS, et al. Impaired recovery and cytolytic function of CD56+ T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation: studies in unselected patients and monozygotic disease-discordant twins. Arthritis Rheum 1996; 39: 1840-51
    • (1996) Arthritis Rheum , vol.39 , pp. 1840-1851
    • Stohl, W.1    Elliott, J.E.2    Hamilton, A.S.3
  • 25
    • 0033065837 scopus 로고    scopus 로고
    • Immune cell signaling defects in lupus: Activation, ancrgy and death
    • Tsokos GC, Liossis S-NC. Immune cell signaling defects in lupus: activation, ancrgy and death. Immunol Today 1999; 20: 119-24
    • (1999) Immunol Today , vol.20 , pp. 119-124
    • Tsokos, G.C.1    Liossis, S.-N.C.2
  • 26
    • 0030848150 scopus 로고    scopus 로고
    • Reduced protein tyrosine phosphatase (PTPase) activity of CD45 on peripheral blood lymphocytes in patients with systemic lupus crythematosus
    • Takeuchi T, Pang M, Amano K, et al. Reduced protein tyrosine phosphatase (PTPase) activity of CD45 on peripheral blood lymphocytes in patients with systemic lupus crythematosus. Clin Exp Immunol 1997; 109: 20-6
    • (1997) Clin Exp Immunol , vol.109 , pp. 20-26
    • Takeuchi, T.1    Pang, M.2    Amano, K.3
  • 27
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TcR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus crythematosus: Deficient expression of the T cell receptor zeta chain
    • Liossis S-NC, Ding XZ, Dennis GJ, et al. Altered pattern of TcR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus crythematosus: deficient expression of the T cell receptor zeta chain. J Clin Invest 1998; 101: 1448-57
    • (1998) J Clin Invest , vol.101 , pp. 1448-1457
    • Liossis, S.-N.C.1    Ding, X.Z.2    Dennis, G.J.3
  • 28
    • 0033494977 scopus 로고    scopus 로고
    • Diminished levels of T cell receptor chains in peripheral blood T lymphocytes from patients with systemic lupus erythematosus
    • Brundula V, Rivas LJ, Blasini AM, et al. Diminished levels of T cell receptor chains in peripheral blood T lymphocytes from patients with systemic lupus erythematosus. Arthritis Rheum 1999; 42: 1908-16
    • (1999) Arthritis Rheum , vol.42 , pp. 1908-1916
    • Brundula, V.1    Rivas, L.J.2    Blasini, A.M.3
  • 29
    • 0032587298 scopus 로고    scopus 로고
    • p561ck activity and expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus
    • Matache C, Stefanescu M, Onu A, et al. p561ck activity and expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus. Autoimmunity 1999; 29: 111-20
    • (1999) Autoimmunity , vol.29 , pp. 111-120
    • Matache, C.1    Stefanescu, M.2    Onu, A.3
  • 30
    • 0029164734 scopus 로고
    • TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus
    • Vassilopoulos D, Kovacs B, Tsokos GC. TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus. J Immunol 1995; 155: 2269-81
    • (1995) J Immunol , vol.155 , pp. 2269-2281
    • Vassilopoulos, D.1    Kovacs, B.2    Tsokos, G.C.3
  • 31
    • 0020444252 scopus 로고
    • Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus
    • Mandler R, Birch RE, Polmar S, et al. Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A 1982; 79: 7542-6
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 7542-7546
    • Mandler, R.1    Birch, R.E.2    Polmar, S.3
  • 32
    • 0025219398 scopus 로고
    • Defective cAMP-dependent phosphorylation of intact T lymphocytes in active systemic lupus erythematosus
    • Hasler P, Schultz LA, Kammer GM. Defective cAMP-dependent phosphorylation of intact T lymphocytes in active systemic lupus erythematosus. Proc Natl Acad Sci U S A 1990; 87: 1978-82
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1978-1982
    • Hasler, P.1    Schultz, L.A.2    Kammer, G.M.3
  • 33
    • 0028278214 scopus 로고
    • Deficient type 1 protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes
    • Kammer GM, Khan IU, Malemud CJ. Deficient type 1 protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes. J Clin Invest 1994; 94: 422-30
    • (1994) J Clin Invest , vol.94 , pp. 422-430
    • Kammer, G.M.1    Khan, I.U.2    Malemud, C.J.3
  • 34
    • 0034284238 scopus 로고    scopus 로고
    • Association of deficient type II protein kinase A activity with aberrant nuclear translocation of the RII-subunit in systemic lupus erythematosus T lymphocytes
    • Mishra N, Khan IU, Tsokos GC, et al. Association of deficient type II protein kinase A activity with aberrant nuclear translocation of the RII-subunit in systemic lupus erythematosus T lymphocytes. J Immunol 2000; 165: 2830-40
    • (2000) J Immunol , vol.165 , pp. 2830-2840
    • Mishra, N.1    Khan, I.U.2    Tsokos, G.C.3
  • 35
    • 0025871709 scopus 로고
    • A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus
    • Tada Y, Nagasawa K, Yamauchi Y, et al. A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1991; 60: 220-31
    • (1991) Clin Immunol Immunopathol , vol.60 , pp. 220-231
    • Tada, Y.1    Nagasawa, K.2    Yamauchi, Y.3
  • 36
    • 0033008814 scopus 로고    scopus 로고
    • Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus
    • Ng TT, Collins IE, Kinner SB, et al. Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus. Lupus 1999; 8: 39-51
    • (1999) Lupus , vol.8 , pp. 39-51
    • Ng, T.T.1    Collins, I.E.2    Kinner, S.B.3
  • 37
    • 0035096761 scopus 로고    scopus 로고
    • Decreased ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
    • Deng C, Kaplan MJ, Yang J, et al. Decreased ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum 2001; 44: 397-407
    • (2001) Arthritis Rheum , vol.44 , pp. 397-407
    • Deng, C.1    Kaplan, M.J.2    Yang, J.3
  • 38
    • 0033179001 scopus 로고    scopus 로고
    • Abnormal NF-κB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression
    • Wong HK, Kammer GM, Dennis G, et al. Abnormal NF-κB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression. J Immunol 1999; 163: 1682-9
    • (1999) J Immunol , vol.163 , pp. 1682-1689
    • Wong, H.K.1    Kammer, G.M.2    Dennis, G.3
  • 39
    • 0035869333 scopus 로고    scopus 로고
    • Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus
    • Solomou EE, Juang Y-T, Gourley MF, et al. Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus. J Immunol 2001; 166: 4216-22
    • (2001) J Immunol , vol.166 , pp. 4216-4222
    • Solomou, E.E.1    Juang, Y.-T.2    Gourley, M.F.3
  • 40
    • 0034519709 scopus 로고    scopus 로고
    • Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients
    • Grolleau A, Kaplan MJ, Hanash SM, et al. Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients. J Clin Invest 2000; 106: 1561-8
    • (2000) J Clin Invest , vol.106 , pp. 1561-1568
    • Grolleau, A.1    Kaplan, M.J.2    Hanash, S.M.3
  • 41
    • 0036161789 scopus 로고    scopus 로고
    • Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus
    • Gergely Jr P, Grossman C, Niland B, et al. Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus. Arthritis Rheum 2002; 46: 175-90
    • (2002) Arthritis Rheum , vol.46 , pp. 175-190
    • Gergely P., Jr.1    Grossman, C.2    Niland, B.3
  • 42
    • 8544257832 scopus 로고
    • Histocompatibility antigens, immune responsiveness and susceptibility to disease
    • McDevitt HO, Bodmer WF. Histocompatibility antigens, immune responsiveness and susceptibility to disease. Am J Med 1972; 52: 1-8
    • (1972) Am J Med , vol.52 , pp. 1-8
    • McDevitt, H.O.1    Bodmer, W.F.2
  • 44
    • 0036148823 scopus 로고    scopus 로고
    • Familial systemic lupus erythematosus: The role of genetic and environmental factors
    • Eroglu GE, Kohler PF. Familial systemic lupus erythematosus: the role of genetic and environmental factors. Ann Rheum Dis 2001; 61: 29-31
    • (2001) Ann Rheum Dis , vol.61 , pp. 29-31
    • Eroglu, G.E.1    Kohler, P.F.2
  • 45
    • 0036676656 scopus 로고    scopus 로고
    • An update on genetic studies of systemic lupus erythematosus
    • Tsao BP. An update on genetic studies of systemic lupus erythematosus. Curr Rheumatol Rep 2002; 4: 359-67
    • (2002) Curr Rheumatol Rep , vol.4 , pp. 359-367
    • Tsao, B.P.1
  • 46
    • 0029560477 scopus 로고
    • Genetics of systemic lupus erythematosus
    • Schur PH. Genetics of systemic lupus erythematosus. Lupus 1995; 4: 425-37
    • (1995) Lupus , vol.4 , pp. 425-437
    • Schur, P.H.1
  • 47
    • 0036256826 scopus 로고    scopus 로고
    • HLA Class II DNA Typing in a Large series of European Patients with Systemic Lupus Erythematosus
    • Galeazzi M, Sebastiani GD, Morozzi G, et al. HLA Class II DNA Typing in a Large series of European Patients with Systemic Lupus Erythematosus. Medicine (Baltimore) 2002; 81: 169-78
    • (2002) Medicine (Baltimore) , vol.81 , pp. 169-178
    • Galeazzi, M.1    Sebastiani, G.D.2    Morozzi, G.3
  • 48
    • 0031810006 scopus 로고    scopus 로고
    • Systemic lupus erythematosus in three ethnic groups: I, the effects of HLA class II, C4, and CR1 alleles, socioeconomic factors, and ethnicity at disease onset. LUMINA Study Group. Lupus in minority populations, nature versus nurture
    • Reveille JD, Moulds JM, Ahn C, et al. Systemic lupus erythematosus in three ethnic groups: I. the effects of HLA class II, C4, and CR1 alleles, socioeconomic factors, and ethnicity at disease onset. LUMINA Study Group. Lupus in minority populations, nature versus nurture. Arthritis Rheum 1998; 41: 1161-72
    • (1998) Arthritis Rheum , vol.41 , pp. 1161-1172
    • Reveille, J.D.1    Moulds, J.M.2    Ahn, C.3
  • 49
    • 0025324131 scopus 로고
    • The effect of ethnicity on major histocompatibility complex, complement allotypes and extended haplotypes in patients with systemic lupus crythcmatosus
    • Schur PH, Marcus B, Awdeh Z, et al. The effect of ethnicity on major histocompatibility complex, complement allotypes and extended haplotypes in patients with systemic lupus crythcmatosus. Arthritis Rheum 1990; 33: 985-92
    • (1990) Arthritis Rheum , vol.33 , pp. 985-992
    • Schur, P.H.1    Marcus, B.2    Awdeh, Z.3
  • 50
    • 0033188361 scopus 로고    scopus 로고
    • Cytokine gene polymorphism in human disease: On-line databases
    • Bidwell J, Keen L, Gallagher G, et al. Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 1999; 1: 3-19
    • (1999) Genes Immun , vol.1 , pp. 3-19
    • Bidwell, J.1    Keen, L.2    Gallagher, G.3
  • 51
    • 0029847906 scopus 로고    scopus 로고
    • Interethnic differences in the association of tumor necrosis factor promoter polymorphisms with systemic lupus erythematosus
    • Rudwaleit M, Tilky M, Khamashtra M, et al. Interethnic differences in the association of tumor necrosis factor promoter polymorphisms with systemic lupus erythematosus. J Rheumatol 1996; 23: 1723-8
    • (1996) J Rheumatol , vol.23 , pp. 1723-1728
    • Rudwaleit, M.1    Tilky, M.2    Khamashtra, M.3
  • 52
    • 0027534914 scopus 로고
    • An allelic polymorphism with the tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, DR3 alleles
    • Wilson AG, De Vries N, Pociot F, et al. An allelic polymorphism with the tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, DR3 alleles. J Exp Med 1993; 177: 557-60
    • (1993) J Exp Med , vol.177 , pp. 557-560
    • Wilson, A.G.1    De Vries, N.2    Pociot, F.3
  • 53
    • 0035673169 scopus 로고    scopus 로고
    • Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: Molecular and functional analysis
    • Morita C, Horiuchi T, Tsukamoto H, et al. Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: molecular and functional analysis. Arthritis Rheum 2001; 44: 2819-27
    • (2001) Arthritis Rheum , vol.44 , pp. 2819-2827
    • Morita, C.1    Horiuchi, T.2    Tsukamoto, H.3
  • 54
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
    • Wilson AG, Symons JA, McDowell TL, et al. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A 1997; 94: 3195-9
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3195-3199
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3
  • 55
    • 0028990471 scopus 로고
    • Inquiry into human and murine lupus
    • Klinman DM, Steinberg AD. Inquiry into human and murine lupus. Immunol Rev 1995; 144: 157-93
    • (1995) Immunol Rev , vol.144 , pp. 157-193
    • Klinman, D.M.1    Steinberg, A.D.2
  • 56
    • 0025016823 scopus 로고
    • Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: Relevance to genetic predisposition to systemic lupus erythematosus
    • Jacob CO, Fronek Z, Lewis GD, et al. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci U S A 1990; 87: 1233-7
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1233-1237
    • Jacob, C.O.1    Fronek, Z.2    Lewis, G.D.3
  • 57
    • 0033752720 scopus 로고    scopus 로고
    • Systemic lupus erythematosus, complement deficiency, and apoptosis
    • Pickering MC, Botto M, Taylor PR, et al. Systemic lupus erythematosus, complement deficiency, and apoptosis. Adv Immunol 2000; 76: 227-324
    • (2000) Adv Immunol , vol.76 , pp. 227-324
    • Pickering, M.C.1    Botto, M.2    Taylor, P.R.3
  • 58
    • 0028093373 scopus 로고
    • Hereditary C1q deficiency and systemic lupus erythematosus
    • Browness P, Davies KA, Norsworthy PJ, et al. Hereditary C1q deficiency and systemic lupus erythematosus. QMJ 1994; 87: 455-64
    • (1994) QMJ , vol.87 , pp. 455-464
    • Browness, P.1    Davies, K.A.2    Norsworthy, P.J.3
  • 59
    • 0022472150 scopus 로고
    • Relationship between C4 null genes, HLA-D region antigens and genetic susceptibility to systemic lupus erythematosus in Caucasian and black Americans
    • Howard PF, Hochberg MC, Bias WB, et al. Relationship between C4 null genes, HLA-D region antigens and genetic susceptibility to systemic lupus erythematosus in Caucasian and black Americans. Am J Med 1986; 81: 187-93
    • (1986) Am J Med , vol.81 , pp. 187-193
    • Howard, P.F.1    Hochberg, M.C.2    Bias, W.B.3
  • 60
    • 0028857358 scopus 로고
    • Mannose-binding protein gene polymorphism in systemic lupus erythematosus
    • Davies EL, Snowden N, Hillarby MC, et al. Mannose-binding protein gene polymorphism in systemic lupus erythematosus. Arthritis Rheum 1995; 38: 110-4
    • (1995) Arthritis Rheum , vol.38 , pp. 110-114
    • Davies, E.L.1    Snowden, N.2    Hillarby, M.C.3
  • 61
    • 0030447092 scopus 로고    scopus 로고
    • Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus
    • Sullivan KE, Wooten C, Goldman D, et al. Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus. Arthritis Rheum 1996; 39: 2046-51
    • (1996) Arthritis Rheum , vol.39 , pp. 2046-2051
    • Sullivan, K.E.1    Wooten, C.2    Goldman, D.3
  • 62
    • 0030947809 scopus 로고    scopus 로고
    • A dysfunctional allele of the mannosc binding protein gene associates with systemic lupus erythematosus in a Spanish population
    • Davies EJ, Teh LS, Ordi-Ros J, et al. A dysfunctional allele of the mannosc binding protein gene associates with systemic lupus erythematosus in a Spanish population. J Rheumatol 1997; 24: 485-8
    • (1997) J Rheumatol , vol.24 , pp. 485-488
    • Davies, E.J.1    Teh, L.S.2    Ordi-Ros, J.3
  • 63
    • 0029866721 scopus 로고    scopus 로고
    • Fc gamma RIIA alleles are heritable risk for SLE nephritis in African Americans
    • Salmon JE, Millard S, Schachter LA, et al. Fc gamma RIIA alleles are heritable risk for SLE nephritis in African Americans. J Clin Invest 1996; 97: 1348-54
    • (1996) J Clin Invest , vol.97 , pp. 1348-1354
    • Salmon, J.E.1    Millard, S.2    Schachter, L.A.3
  • 64
    • 13344279426 scopus 로고
    • Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients
    • Duits AJ, Bootsma H, Derksen R, et al. Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients. Arthritis Rheum 1995; 39: 1832-6
    • (1995) Arthritis Rheum , vol.39 , pp. 1832-1836
    • Duits, A.J.1    Bootsma, H.2    Derksen, R.3
  • 65
    • 0035089823 scopus 로고    scopus 로고
    • Low-binding alleles of Fcgamma receptor types IIA and IIIA are inherited independently and are associated with systemic lupus erythematosus in Hispanic patients
    • Zuniga R, Ng S, Peterson MG, et al. Low-binding alleles of Fcgamma receptor types IIA and IIIA are inherited independently and are associated with systemic lupus erythematosus in Hispanic patients. Arthritis Rheum 2001; 44: 361-7
    • (2001) Arthritis Rheum , vol.44 , pp. 361-367
    • Zuniga, R.1    Ng, S.2    Peterson, M.G.3
  • 66
    • 0029981461 scopus 로고    scopus 로고
    • Fc gamma RIIa polymorphism in systemic lupus erythematosus (SLE): No association with disease
    • Botto M, Theodoridis E, Thompson EM, et al. Fc gamma RIIa polymorphism in systemic lupus erythematosus (SLE): no association with disease. Clin Exp Immunol 1996; 104; 264-8
    • (1996) Clin Exp Immunol , vol.104 , pp. 264-268
    • Botto, M.1    Theodoridis, E.2    Thompson, E.M.3
  • 67
    • 0034121689 scopus 로고    scopus 로고
    • Systemic lupus erythematosus candidate genes in the Italian population: Evidence for a significant association with interleukin-10
    • D'Alfonso S, Rampi M, Bocchio D, et al. Systemic lupus erythematosus candidate genes in the Italian population: evidence for a significant association with interleukin-10. Arthritis Rheum 2000; 43: 120-8
    • (2000) Arthritis Rheum , vol.43 , pp. 120-128
    • D'Alfonso, S.1    Rampi, M.2    Bocchio, D.3
  • 68
    • 0032588691 scopus 로고    scopus 로고
    • Altered distribution of Fcgamma receptor IIIA alleles in a cohort of Korean patients with lupus nephritis
    • Salmon JE, Ng S, Yoo DH, et al. Altered distribution of Fcgamma receptor IIIA alleles in a cohort of Korean patients with lupus nephritis. Arthritis Rheum 1999; 42: 818-9
    • (1999) Arthritis Rheum , vol.42 , pp. 818-819
    • Salmon, J.E.1    Ng, S.2    Yoo, D.H.3
  • 69
    • 0000220519 scopus 로고    scopus 로고
    • Abnormal distribution of Fc gamma receptor type IIa polymorphisms in Korean patients with systemic lupus erythematosus
    • Song YW, Han CW, Kang SW, et al. Abnormal distribution of Fc gamma receptor type IIa polymorphisms in Korean patients with systemic lupus erythematosus. Arthritis Rheum 1998; 41: 421-6
    • (1998) Arthritis Rheum , vol.41 , pp. 421-426
    • Song, Y.W.1    Han, C.W.2    Kang, S.W.3
  • 70
    • 0031596490 scopus 로고    scopus 로고
    • Fcg receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: Association with clinical symptoms
    • Manger K, Repp R, Spriewald BM, et al. Fcg receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms. Arthritis Rheum 1998; 41: 1181-9
    • (1998) Arthritis Rheum , vol.41 , pp. 1181-1189
    • Manger, K.1    Repp, R.2    Spriewald, B.M.3
  • 71
    • 0034353414 scopus 로고    scopus 로고
    • Fc gamma receptor polymorphisms in systemic lupus erythematosus: Association with disease and in vivo clearance of immune complexes
    • Dijstelbloem HM, Biji M, Fijnhcer R, et al. Fc gamma receptor polymorphisms in systemic lupus erythematosus: association with disease and in vivo clearance of immune complexes. Arthritis Rheum 2000; 43: 2793-800
    • (2000) Arthritis Rheum , vol.43 , pp. 2793-2800
    • Dijstelbloem, H.M.1    Biji, M.2    Fijnhcer, R.3
  • 72
    • 0030680185 scopus 로고    scopus 로고
    • Antibodies to Clq in systemic lupus erythematosus: Characteristics and relation to Fc gamma RIIA alleles
    • Hasclcy LA, Wisnieski JJ, Denburg MR, et al. Antibodies to Clq in systemic lupus erythematosus: characteristics and relation to Fc gamma RIIA alleles. Kidney Int 1997; 52: 1375-80
    • (1997) Kidney Int , vol.52 , pp. 1375-1380
    • Hasclcy, L.A.1    Wisnieski, J.J.2    Denburg, M.R.3
  • 73
    • 0033238172 scopus 로고    scopus 로고
    • Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasian systemic lupus erythematosus patients with autoantibodies to Clq and glomerulonephritis
    • Norsworthy P, Theodoridis E, Botto M, et al. Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasian systemic lupus erythematosus patients with autoantibodies to Clq and glomerulonephritis. Arthritis Rheum 1999; 42: 1828-32
    • (1999) Arthritis Rheum , vol.42 , pp. 1828-1832
    • Norsworthy, P.1    Theodoridis, E.2    Botto, M.3
  • 74
    • 0031595344 scopus 로고    scopus 로고
    • The Fc gammaRIIIA-158F allele is a risk factor for systemic lupus erythematosus
    • Koene HR, Kleijer M, Swaak AJ, et al. The Fc gammaRIIIA-158F allele is a risk factor for systemic lupus erythematosus. Arthritis Rheum 1998; 41: 1813-8
    • (1998) Arthritis Rheum , vol.41 , pp. 1813-1818
    • Koene, H.R.1    Kleijer, M.2    Swaak, A.J.3
  • 75
    • 0030611089 scopus 로고    scopus 로고
    • A novel polymorphism of FcyRIIIa (CD 16) alters receptor function and predisposes to autoimmune disease
    • Wu J, Edberg JC, Redecha PB, et al. A novel polymorphism of FcyRIIIa (CD 16) alters receptor function and predisposes to autoimmune disease. J Clin Invest 1997; 100: 1059-70
    • (1997) J Clin Invest , vol.100 , pp. 1059-1070
    • Wu, J.1    Edberg, J.C.2    Redecha, P.B.3
  • 76
    • 0036676085 scopus 로고    scopus 로고
    • Genetic linkage and association of Fcã receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus
    • Edberg JC, Langfeld CD, Wu J, et al. Genetic linkage and association of Fcã receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2132-40
    • (2002) Arthritis Rheum , vol.46 , pp. 2132-2140
    • Edberg, J.C.1    Langfeld, C.D.2    Wu, J.3
  • 77
    • 0035983742 scopus 로고    scopus 로고
    • Fc gamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: Contribution of FCGR2B to genetic susceptibility
    • Kyogoku C, Dijstelbloem HM, Tsuchiya N, et al. Fc gamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. Arthritis Rheum 2002; 46: 1242-54
    • (2002) Arthritis Rheum , vol.46 , pp. 1242-1254
    • Kyogoku, C.1    Dijstelbloem, H.M.2    Tsuchiya, N.3
  • 78
    • 4243900937 scopus 로고    scopus 로고
    • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome Iq in African-American pedigrees
    • Moser KL, Ncas BR, Salmon JE, et al. Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome Iq in African-American pedigrees. Proc Natl Acad Sci U S A 1998; 95: 14869-74
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14869-14874
    • Moser, K.L.1    Ncas, B.R.2    Salmon, J.E.3
  • 79
    • 0032483014 scopus 로고    scopus 로고
    • Interleukin 10 secretion in relation to human IL-10 locus haplotypes
    • Eskdale J, Gallagher G, Verweij CL, et al. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc Natl Acad Sci U S A 1998; 95: 9465-70
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9465-9470
    • Eskdale, J.1    Gallagher, G.2    Verweij, C.L.3
  • 80
    • 0031926054 scopus 로고    scopus 로고
    • Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus
    • Mehrian R, Quismorio FP, Strassmann G, et al. Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus. Arthritis Rheum 1998; 41: 596-602
    • (1998) Arthritis Rheum , vol.41 , pp. 596-602
    • Mehrian, R.1    Quismorio, F.P.2    Strassmann, G.3
  • 81
    • 2942643251 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus
    • Mok CC, Lanchbury JS, Chan DW, et al. Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus. Arthritis Rheum 1998; 41: 1090-5
    • (1998) Arthritis Rheum , vol.41 , pp. 1090-1095
    • Mok, C.C.1    Lanchbury, J.S.2    Chan, D.W.3
  • 82
    • 0031453916 scopus 로고    scopus 로고
    • Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus
    • Lazarus M, Hajeer AH, Turner D, et al. Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus. J Rheumatol 1997; 24: 2314-7
    • (1997) J Rheumatol , vol.24 , pp. 2314-2317
    • Lazarus, M.1    Hajeer, A.H.2    Turner, D.3
  • 83
    • 0036176702 scopus 로고    scopus 로고
    • Asssociation of vitamin D receptor gene BsmI polymorphisms in Chinese patients with systemic lupus erythematosus
    • Huang CM, Wu MC, Wu JY, et al. Asssociation of vitamin D receptor gene BsmI polymorphisms in Chinese patients with systemic lupus erythematosus. Lupus 2002; 11: 31-4
    • (2002) Lupus , vol.11 , pp. 31-34
    • Huang, C.M.1    Wu, M.C.2    Wu, J.Y.3
  • 84
    • 0034054443 scopus 로고    scopus 로고
    • Vitamin-D receptor genotype and renal disorder in Japanes patients with systemic lupus erythematosus
    • Ozaki Y, Nomura S, Nagahama M, et al. Vitamin-D receptor genotype and renal disorder in Japanes patients with systemic lupus erythematosus. Nephron 2000; 85: 86-91
    • (2000) Nephron , vol.85 , pp. 86-91
    • Ozaki, Y.1    Nomura, S.2    Nagahama, M.3
  • 85
    • 15144359976 scopus 로고    scopus 로고
    • Angiotensin I converting enzyme gene polymorphisms in systemic lupus erythematosus: Decreased prevalence of DD genotype in African American patients
    • Tassiulas IO, Aksentijevich I, Salmon JE, et al. Angiotensin I converting enzyme gene polymorphisms in systemic lupus erythematosus: decreased prevalence of DD genotype in African American patients. Clin Nephrol 1998; 50: 8-13
    • (1998) Clin Nephrol , vol.50 , pp. 8-13
    • Tassiulas, I.O.1    Aksentijevich, I.2    Salmon, J.E.3
  • 86
    • 0031773383 scopus 로고    scopus 로고
    • Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of systemic lupus erythematosus
    • Sato H, Akai Y, Iwano M, et al. Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of systemic lupus erythematosus. Lupus 1998; 7: 530-4
    • (1998) Lupus , vol.7 , pp. 530-534
    • Sato, H.1    Akai, Y.2    Iwano, M.3
  • 87
    • 0033010292 scopus 로고    scopus 로고
    • Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of lupus nephritis
    • Akai Y, Sato H, Iwano M, et al. Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of lupus nephritis. Clin Nephrology 1999; 51: 141-6
    • (1999) Clin Nephrology , vol.51 , pp. 141-146
    • Akai, Y.1    Sato, H.2    Iwano, M.3
  • 88
    • 6544282769 scopus 로고    scopus 로고
    • Association between systemic lupus erythematosus and insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene
    • Pullmann Jr R, Lukac J, Skerenova M, et al. Association between systemic lupus erythematosus and insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene. Clin Exp Rheumatol 1999; 17: 593-6
    • (1999) Clin Exp Rheumatol , vol.17 , pp. 593-596
    • Pullmann R., Jr.1    Lukac, J.2    Skerenova, M.3
  • 89
    • 0033783881 scopus 로고    scopus 로고
    • Renal outcome and vascular morbidity in systemic lupus erythematosus (SLE): Lack of association with the angiotensin-converting enzyme gene polymorphism
    • Molad Y, Gal E, Magal N, et al. Renal outcome and vascular morbidity in systemic lupus erythematosus (SLE): lack of association with the angiotensin-converting enzyme gene polymorphism. Semin Arthritis Rheum 2000; 30: 132-7
    • (2000) Semin Arthritis Rheum , vol.30 , pp. 132-137
    • Molad, Y.1    Gal, E.2    Magal, N.3
  • 90
    • 0035947034 scopus 로고    scopus 로고
    • Linkage analysis of angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and systemic lupus erythematosus
    • Kaufman KM, Kelly J, Gray-McGuire C, et al. Linkage analysis of angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and systemic lupus erythematosus. Mol Cell Enocrinol 2001; 177: 81-5
    • (2001) Mol Cell Enocrinol , vol.177 , pp. 81-85
    • Kaufman, K.M.1    Kelly, J.2    Gray-McGuire, C.3
  • 91
    • 0033384968 scopus 로고    scopus 로고
    • Lack of a strong association of CTLA-4 exon 1 polymorphism with the susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese: An association study using a novel variation screening method
    • Matsushita M, Tsuchiya N, Shiota M, et al. Lack of a strong association of CTLA-4 exon 1 polymorphism with the susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese: an association study using a novel variation screening method. Tissue Antigens 1999; 54: 578-84
    • (1999) Tissue Antigens , vol.54 , pp. 578-584
    • Matsushita, M.1    Tsuchiya, N.2    Shiota, M.3
  • 92
    • 0002595674 scopus 로고    scopus 로고
    • The genetics of human lupus
    • Wallace DJ, Hahn BH, editors. Philadelphia (PA): Lippincott Williams and Wilkins
    • Tsao BP. The genetics of human lupus. In: Wallace DJ, Hahn BH, editors. Dubois' lupus erythematosus. Philadelphia (PA): Lippincott Williams and Wilkins, 2002: 97-120
    • (2002) Dubois' Lupus Erythematosus , pp. 97-120
    • Tsao, B.P.1
  • 93
    • 0036560022 scopus 로고    scopus 로고
    • Abnormal T cell signal transduction in systemic lupus erythematosus
    • Kammer GM, Perl A, Richardson BC, et al. Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum 2002; 46: 1139-54
    • (2002) Arthritis Rheum , vol.46 , pp. 1139-1154
    • Kammer, G.M.1    Perl, A.2    Richardson, B.C.3
  • 94
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibitity to systemic lupus erythematosus in humans
    • Prokunina L, Castillejo-Lopez C, Oberg F, et al. A regulatory polymorphism in PDCD1 is associated with susceptibitity to systemic lupus erythematosus in humans. Nat Genet 2002; 32: 666-9
    • (2002) Nat Genet , vol.32 , pp. 666-669
    • Prokunina, L.1    Castillejo-Lopez, C.2    Oberg, F.3
  • 95
    • 0031027561 scopus 로고    scopus 로고
    • Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus
    • Tsao BP, Cantor RM, Kalunian KC, et al. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest 1997; 99: 725-31
    • (1997) J Clin Invest , vol.99 , pp. 725-731
    • Tsao, B.P.1    Cantor, R.M.2    Kalunian, K.C.3
  • 96
    • 0033848380 scopus 로고    scopus 로고
    • A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q
    • Lindqvist AK, Steinsson K, Johanneson B, et al. A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q. J Autoimmun 2000; 14: 169-78
    • (2000) J Autoimmun , vol.14 , pp. 169-178
    • Lindqvist, A.K.1    Steinsson, K.2    Johanneson, B.3
  • 97
    • 0033647280 scopus 로고    scopus 로고
    • Genome scan of human systemic lupus erythematosus by regression modeling: Evidence of linkage and epistasis at 4p16-15.2
    • Gray-McCuire C, Moser KL, Gaffney PM, et al. Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. Am J Hum Genet 2000; 67: 1460-9
    • (2000) Am J Hum Genet , vol.67 , pp. 1460-1469
    • Gray-McCuire, C.1    Moser, K.L.2    Gaffney, P.M.3
  • 98
    • 4243900858 scopus 로고    scopus 로고
    • A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
    • Gaffney PM, Kearns CM, Shark KB, et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci U S A 1998; 95: 14875-9
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14875-14879
    • Gaffney, P.M.1    Kearns, C.M.2    Shark, K.B.3
  • 99
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417-29
    • (2002) N Engl J Med , vol.347 , pp. 417-429
    • Podolsky, D.K.1
  • 100
    • 0033560931 scopus 로고    scopus 로고
    • PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus
    • Tsao BP, Cantor RM, Grossman M, et al. PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus. J Clin Invest 1999; 103: 1135-40
    • (1999) J Clin Invest , vol.103 , pp. 1135-1140
    • Tsao, B.P.1    Cantor, R.M.2    Grossman, M.3
  • 101
    • 0033840495 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase polymorphisms are not a genetic risk factor for systemic lupus erythematosus in German Caucasians
    • Boorboor P, Drescher BE, Hartung K, et al. Poly(ADP-ribose) polymerase polymorphisms are not a genetic risk factor for systemic lupus erythematosus in German Caucasians [letter]. J Rheumatol 2000; 27: 2061
    • (2000) J Rheumatol , vol.27 , pp. 2061
    • Boorboor, P.1    Drescher, B.E.2    Hartung, K.3
  • 102
    • 0034121119 scopus 로고    scopus 로고
    • PARP alleles and SLE: Failure to confirm association with disease susceptibility
    • Criswell LA, Moser KL, Gaffney PM, et al. PARP alleles and SLE: failure to confirm association with disease susceptibility. J Clin Invest 2000; 105: 1501-2
    • (2000) J Clin Invest , vol.105 , pp. 1501-1502
    • Criswell, L.A.1    Moser, K.L.2    Gaffney, P.M.3
  • 103
    • 0034041234 scopus 로고    scopus 로고
    • Searching for genes in complex diseases: Lessons from systemic lupus erythematosus
    • Risch N. Searching for genes in complex diseases: lessons from systemic lupus erythematosus. J Clin Invest 2000; 105: 1503-6
    • (2000) J Clin Invest , vol.105 , pp. 1503-1506
    • Risch, N.1
  • 104
    • 0037305577 scopus 로고    scopus 로고
    • Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13
    • Feb 1
    • Scofield RH, Bruner GR, Kelly JA, et al. Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13. Blood 2003 Feb 1; 101 (3): 992-7
    • (2003) Blood , vol.101 , Issue.3 , pp. 992-997
    • Scofield, R.H.1    Bruner, G.R.2    Kelly, J.A.3
  • 105
    • 18544367517 scopus 로고    scopus 로고
    • Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia
    • Kelly J, Thompson K, Kilpatrick J, et al. Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia. Proc Natl Acad Sci U S A 2002; 99: 11766-71
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11766-11771
    • Kelly, J.1    Thompson, K.2    Kilpatrick, J.3
  • 106
    • 0036845210 scopus 로고    scopus 로고
    • Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3
    • Namjou B, Nath SK, Kilpatrick J, et al. Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3. Arthritis Rheum 2002; 46: 2937-45
    • (2002) Arthritis Rheum , vol.46 , pp. 2937-2945
    • Namjou, B.1    Nath, S.K.2    Kilpatrick, J.3
  • 107
    • 0036822311 scopus 로고    scopus 로고
    • Familiarity and co-occurence of clinical features of systemic lupus erythematosus
    • Tsao BP, Grossman JM, Riekmekasten G, et al. Familiarity and Co-occurence of clinical features of systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2678-85
    • (2002) Arthritis Rheum , vol.46 , pp. 2678-2685
    • Tsao, B.P.1    Grossman, J.M.2    Riekmekasten, G.3
  • 108
    • 34547481484 scopus 로고    scopus 로고
    • Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2)
    • Namjou B, Nath S, Kilpatrick J, et al. Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2). Genes Immun 2002; 3 Suppl. 1: S35-4
    • (2002) Genes Immun , vol.3 , Issue.SUPPL. 1
    • Namjou, B.1    Nath, S.2    Kilpatrick, J.3
  • 109
    • 34547414073 scopus 로고    scopus 로고
    • The genetics of systemic lupus erythematosus stratified by renal disease: Linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3)
    • Quintero-Del-Rio AI, Kelly JA, Kilpatrick J, et al. The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). Genes Immun 2002; 3 Suppl. 1: S57-62
    • (2002) Genes Immun , vol.3 , Issue.SUPPL. 1
    • Quintero-Del-Rio, A.I.1    Kelly, J.A.2    Kilpatrick, J.3
  • 110
    • 0036846043 scopus 로고    scopus 로고
    • Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus
    • Tsao BP, Cantor RM, Grossman JM, et al. Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2928-36
    • (2002) Arthritis Rheum , vol.46 , pp. 2928-2936
    • Tsao, B.P.1    Cantor, R.M.2    Grossman, J.M.3
  • 111
    • 0033927668 scopus 로고    scopus 로고
    • Gene therapy in the treatment of autoimmune diseases
    • Tsokos GC, Neprom GT. Gene therapy in the treatment of autoimmune diseases. J Clin Invest 2000; 106: 181-3
    • (2000) J Clin Invest , vol.106 , pp. 181-183
    • Tsokos, G.C.1    Neprom, G.T.2
  • 112
    • 0029929607 scopus 로고    scopus 로고
    • Defective antigen presenting cell function in patients with systemic lupus erythematosus: Role of the B7/BB1(CD80) costimulatory molecule
    • Tsokos GC, Kovacs F, Sfikakis PP, et al. Defective antigen presenting cell function in patients with systemic lupus erythematosus: Role of the B7/BB1(CD80) costimulatory molecule. Arthritis Rheum 1996; 39: 600-9
    • (1996) Arthritis Rheum , vol.39 , pp. 600-609
    • Tsokos, G.C.1    Kovacs, F.2    Sfikakis, P.P.3
  • 113
    • 0027208746 scopus 로고
    • Multiple T cell-antigen presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects
    • Via CS, Tsokos GC, Bermas B, et al. Multiple T cell-antigen presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects. J Immunol 1993; 151: 3914-22
    • (1993) J Immunol , vol.151 , pp. 3914-3922
    • Via, C.S.1    Tsokos, G.C.2    Bermas, B.3
  • 114
    • 0029862632 scopus 로고    scopus 로고
    • Immunopathogenesis and spectrum of infections in systemic lupus erythematosus
    • Iliopoulos AG, Tsokos GC. Immunopathogenesis and spectrum of infections in systemic lupus erythematosus. Semin Arthritis Rheum 1996; 25: 318-36
    • (1996) Semin Arthritis Rheum , vol.25 , pp. 318-336
    • Iliopoulos, A.G.1    Tsokos, G.C.2
  • 115
    • 0036264363 scopus 로고    scopus 로고
    • Electroporation-mediated gene transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity
    • Herndon TM, Juang Y-T, Solomou E, et al. Electroporation-mediated gene transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity. Clin Immunol 2002; 103: 145-53
    • (2002) Clin Immunol , vol.103 , pp. 145-153
    • Herndon, T.M.1    Juang, Y.-T.2    Solomou, E.3
  • 116
    • 0037108487 scopus 로고    scopus 로고
    • Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus
    • Tenbrock K, Juang Y-T, Gourley MF, et al. Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus. J Immunol 2002; 169: 4147-52
    • (2002) J Immunol , vol.169 , pp. 4147-4152
    • Tenbrock, K.1    Juang, Y.-T.2    Gourley, M.F.3


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