Adeno-associated virus 2-mediated gene therapy decreases autofluorescent storage material and increases brain mass in a murine model of infantile neuronal ceroid lipofuscinosis

Neurobiology of Disease

Volumn 16, Issue 2, 2004, Pages 360-369

  Griffey, Megan ^a   Bible, Ellen ^b   Vogler, Carole ^c   Levy, Beth ^c   Gupta, Praveena ^d   Cooper, Jonathan ^b   Sands, Mark S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Adeno associated virus; Batten disease; Gene therapy; Infantile neuronal ceroid lipofuscinosis; Lysosomal storage disease; Neurodegenerative disease; Palmitoyl protein thioesterase

Indexed keywords

ADENOVIRUS VECTOR; PALMITOYL PROTEIN THIOESTERASE; PALMITOYL PROTEIN THIOESTERASE 1; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; BRAIN CORTEX; BRAIN WEIGHT; CEREBELLUM; CONTROLLED STUDY; DISEASE MODEL; GENE THERAPY; HIPPOCAMPUS; MOUSE; NERVE CELL; NEURONAL CEROID LIPOFUSCINOSIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL;

ADENOVIRIDAE; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; FLUORESCENCE; GENE THERAPY; HUMANS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NEURONAL CEROID-LIPOFUSCINOSES; THIOLESTER HYDROLASES;

EID: 2942588715     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.03.005     Document Type: Article

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