Co-stimulation and plaque-antigen-specific T-cell responses in atherosclerosis

Trends in Cardiovascular Medicine

Volumn 14, Issue 4, 2004, Pages 166-172

  Buono, Chiara ^a   Lichtman, Andrew H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; B7 ANTIGEN; BETA2 GLYCOPROTEIN 1; CD28 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; IA ANTIGEN; IMMUNOGLOBULIN; T LYMPHOCYTE ANTIGEN;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL FUNCTION; CELL MIGRATION; CELL STIMULATION; CELLULAR IMMUNITY; CHRONIC INFLAMMATION; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSTIMULATION; INFLAMMATION; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 2942560603     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2004.03.001     Document Type: Review

References (60)

1. Afek A., George J., Gilburd B., et al. Immunization of low-density lipoprotein receptor deficient (LDL-RD) mice with heat shock protein 65 (hsp-65) promotes early atherosclerosis. J Autoimmun. 14:2000;115-121
2. Albert L.J., Inman R.D. Molecular mimicry and autoimmunity. N Engl J Med. 341:1999;2068-2074
3. Binder C.J., Chang M.K., Shaw P.X., et al. Innate and acquired immunity in atherogenesis. Nat Med. 8:2002;1218-1226
4. Bobryshev Y.V. Dendritic cells and their involvement in atherosclerosis. Curr Opin Lipidol. 11:2000;511-517
5. Bobryshev Y.V., Lord R.S. CD1 expression and the nature of CD1-expressing cells in human atherosclerotic plaques. Am J Pathol. 156:2000;1477-1478
6. Borriello F., Sethna M.P., Boyd S.D., et al. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity. 6:1997;303-313
7. Bulut Y., Faure E., Thomas L., et al. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD22 in a MYD88-dependent pathway. J Immunol. 168:2002;1435-1440
8. Buono C., Come C.E., Stavrakis G., et al. Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse. Arterioscler Thromb Vasc Biol. 23:2003;454-460
9. Buono C., Pang H., Uchida Y., et al. B7-1/B7-2 co-stimulation regulates plaque antigen-specific T cell responses and atherogenesis in LDLR-deficient mice. Circulation. 109:2004;2009-2015
10. Carreno B.M., Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol. 20:2002;29-53
11. Chang T.T., Jabs C., Sobel R.A., et al. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. J Exp Med. 190:1999;733-740
12. Choi J., Chung S.W., Kim S.J. Establishment of Porphyromonas gingivalis-specific T-cell lines from atherosclerosis patients. Oral Microbiol Immunol. 16:2001;316-318
13. Costa C.P., Kirschning C.J., Busch D., et al. Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae. Eur J Immunol. 32:2002;2460-2470
14. Curry A.J., Portig I., Goodall J.C., et al. T lymphocyte lines isolated from atheromatous plaque contain cells capable of responding to Chlamydia antigens. Clin Exp Immunol. 121:2000;261-269
15. Daugherty A. Mouse models of atherosclerosis. Am J Med Sci. 323:2002;3-10
16. de Boer O.J., van der Wal A.C., Houtkamp M.A., et al. Unstable atherosclerotic plaques contain T-cells that respond to Chlamydia pneumoniae. Cardiovasc Res. 48:2000;402-408
17. Ding L., Green J.M., Thompson C.B., et al. B7/CD28-dependent and -independent induction of CD40 ligand expression. J Immunol. 155:1995;5124-5132
18. Freigang S., Horkko S., Miller E., et al. Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler Thromb Vasc Biol. 18:1998;1972-1982
19. Frostegard J., Ulfgren A.K., Nyberg P., et al. Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis. 145:1999;33-43
20. George J., Afek A., Gilburd B., et al. Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I. Circulation. 98:1998;1108-1115
21. George J., Shoenfeld Y., Afek A., et al. Enhanced fatty streak formation in C57Bl/6J mice by immunization with heat shock protein-65. Arterioscler Thromb Vasc Biol. 19:1999;505-510
22. George J., Harats D., Gilburd B., et al. Adoptive transfer of beta(2)-glycoprotein I-reactive lymphocytes enhances early atherosclerosis in LDL receptor-deficient mice. Circulation. 102:2000;1822-1827
23. George J., Afek A., Gilburd B., et al. Cellular and humoral immune responses to heat shock protein 65 are both involved in promoting fatty-streak formation in LDL-receptor deficient mice. J Am Coll Cardiol. 38:2001;900-905
24. Guermonprez P., Valladeau J., Zitvogel L., et al. Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol. 20:2002;621-667
25. Gupta S., Pablo A.M., Jiang X., et al. IFN-gamma potentiates atherosclerosis in apoE knock-out mice. J Clin Invest. 99:1997;2752-2761
26. Hansson G.K., Zhou X., Tornquist E., et al. The role of adaptive immunity in atherosclerosis. Ann NY Acad Sci. 902:2000;53-62
27. Kiechl S., Lorenz E., Reindl M., et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med. 347:2002;185-192
28. Kleindienst R., Xu Q., Willeit J., et al. Immunology of atherosclerosis. Demonstration of heat shock protein 60. Am J Pathol. 142:1993;1927-1937
29. Knoflach M., Kiechl S., Kind M., et al. Cardiovascular risk factors and atherosclerosis in young males: Army study. Circulation. 108:2003;1064-1069
30. Kol A., Libby P. Molecular mediators of arterial inflammation: a role for microbial products? Am Heart J. 138:1999;S450-S452
31. Kol A., Sukhova G.K., Lichtman A.H., et al. Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression. Circulation. 98:1998;300-307
32. Laurat E., Poirier B., Tupin E., et al. In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation. 104:2001;197-202
33. Lee T.S., Yen H.C., Pan C.C., et al. The role of interleukin 12 in the development of atherosclerosis in apoE-deficient mice. Arterioscler Thromb Vasc Biol. 19:1999;734-742
34. Libby P. Inflammation in atherosclerosis. Nature. 420:2002;868-874
35. Mach F., Schonbeck U., Sukhova G.K., et al. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature. 394:1998;200-203
36. Mahdi O.S., Horne B.D., Mullen K., et al. Serum immunoglobulin G antibodies to chlamydial heat shock protein 60 but not to human and bacterial homologs are associated with coronary artery disease. Circulation. 106:2002;1659-1663
37. Mallat Z., Gojova A., Brun V., et al. Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice. Circulation. 108:2003;1232-1237
38. Mayr M., Kiechl S., Willeit J., et al. Infections, immunity, and atherosclerosis: associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosis. Circulation. 102:2000;833-839
39. + T cells. Immunol Rev. 165:1998;231-247
40. Melian A., Geng Y.J., Sukhova G.K., et al. CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells. Am J Pathol. 155:1999;775-786
41. Miller Y.I., Chang M.K., Binder C.J., et al. Oxidized low density lipoprotein and innate immune receptors. Curr Opin Lipidol. 14:2003;437-445
42. Millonig G., Schwentner C., Mueller P., et al. The vascular-associated lymphoid tissue: a new site of local immunity. Curr Opin Lipidol. 12:2001;547-553
43. Mosorin M., Surcel H.M., Laurila A., et al. Detection of Chlamydia pneumoniae-reactive T lymphocytes in human atherosclerotic plaques of carotid artery. Arterioscler Thromb Vasc Biol. 20:2000;1061-1067
44. Palinski W., Miller E., Witztum J.L. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci USA. 92:1995a;821-825
45. Palinski W., Tangirala R.K., Miller E., et al. Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler Thromb Vasc Biol. 15:1995b;1569-1576
46. Schonbeck U., Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci. 58:2001;4-43
47. Sharpe A.H., Freeman G.J. The B7-CD28 superfamily. Nat Rev Immunol. 2:2002;116-126
48. Song L., Leung C., Schindler C. Lymphocytes are important in early atherosclerosis. J Clin Invest. 108:2001;251-259
49. Stemme S., Faber B., Holm J., et al. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci USA. 92:1995;3893-3897
50. Takeda K., Kaisho T., Akira S. Toll-like receptors. Annu Rev Immunol. 21:2003;335-376
51. Tupin E., Nicoletti A., Elhage R., et al. CD1D-dependent activation of NKT cells aggravates atherosclerosis. J Exp Med. 199:2004;417-422
52. Veres A., Fust G., Smieja M., et al. Relationship of anti-60 kDa heat shock protein and anti-cholesterol antibodies to cardiovascular events. Circulation. 106:2002;2775-2780
53. Virella G., Virella I., Leman R.B., et al. Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers. Int J Clin Lab Res. 23:1993;95-101
54. -/- mice. J Interferon Cytokine Res. 22:2002;661-670
55. Wick G., Perschinka H., Millonig G. Atherosclerosis as an autoimmune disease: an update. Trends Immunol. 22:2001;665-669
56. Xu Q., Dietrich H., Steiner H.J., et al. Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65. Arterioscler Thromb. 12:1992;789-799
57. Xu Q., Kleindienst R., Waitz W., et al. Increased expression of heat shock protein 65 coincides with a population of infiltrating T lymphocytes in atherosclerotic lesions of rabbits specifically responding to heat shock protein 65. J Clin Invest. 91:1993a;2693-2702
58. Xu Q., Willeit J., Marosi M., et al. Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. Lancet. 341:1993b;255-259
59. Yi Y., Yang X., Brunham R.C. Autoimmunity to heat shock protein 60 and antigen-specific production of interleukin-10. Infect Immun. 65:1997;1669-1674
60. Zhou X., Caligiuri G., Hamsten A., et al. LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler Thromb Vasc Biol. 21:2001;108-114