Molecular mediators of arterial inflammation: A role for microbial products?

American Heart Journal

Volumn 138, Issue 5 II, 1999, Pages

  Kol, A ^a   Libby, P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ATHEROSCLEROSIS; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONFERENCE PAPER; DISEASE ASSOCIATION; HUMAN; IMMUNOPATHOGENESIS; INFLAMMATION; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0032694363     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0002-8703(99)70273-5     Document Type: Conference Paper

References (11)

1. Libby P. Molecular bases of the acute coronary syndromes. Circulation 1995;91:2844-50.
2. Gotto AM Jr. Assessing the benefits of lipid-lowering therapy. Am J Cardiol 1998;82:2M-4M.
3. Libby P, Egan D, Skarlatos S. Role of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. Circulation 1997;96:4095-103.
4. Kol A, Libby P. The mechanisms by which infectious agents may contribute to atherosclerosis and its clinical manifestations. Trends Cardiovasc Med 1998;8:191-9.
5. Davidson M, Kuo CC, Middaugh JP, et al. Confirmed previous infection with Chlamydia pneumoniae (TWAR) and its presence in early coronary atherosclerosis. Circulation 1998;98:628-33.
6. Grayston JT. Antibiotic treatment of Chlamydia pneumoniae for secondary prevention of cardiovascular events. Circulation 1998;97:1669-70.
7. Kalayoglu MV, Byrne GI. A chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharide. Infect Immun 1998;66:5067-72.
8. Laurila A, Bloigu A, Nayha S, et al. Chronic Chlamydia pneumoniae infection is associated with a serum lipid profile known to be a risk factor for atherosclerosis. Arterioscler Thromb Vasc Biol 1997;17:2910-3.
9. Beatty WL, Morrison RP, Byrne GI. Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis. Microbiol Rev 1994;58:686-99.
10. Kleindienst R, Xu Q, Willeit J, et al. Immunology of atherosclerosis: demonstration of heat shock protein 60 expression and T lymphocytes bearing alpha/beta or gamma/delta receptor in human atherosclerotic lesions. Am J Pathol 1993;142:1927-37.
11. Kol A, Sukhova GK, Lichtman AH, et al. Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression. Circulation 1998;98:300-7.