Cadmium induces caspase-independent apoptosis in liver Hep3B cells: Role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor

Free Radical Biology and Medicine

Volumn 36, Issue 12, 2004, Pages 1517-1531

  Lemarié, Anthony ^a   Lagadic Gossmann, Dominique ^a   Morzadec, Claudie ^a   Allain, Nathalie ^a   Fardel, Olivier ^a   Vernhet, Laurent ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

Author keywords

A5; AIF; annexin V; Apoptosis; apoptosis inducing factor; Bapta AM; Cadmium; Calcium; Endonuclease G; Free radicals; Mitochondrial toxicity; Nuclear factor B inhibition; Oxidative stress

Indexed keywords

5,5' DIMETHYLBIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; APOPTOSIS INDUCING FACTOR; CADMIUM; CALCIUM; CALCIUM CHELATING AGENT; CASPASE; DIPHENYLIODONIUM SALT; ENDONUCLEASE; ENDONUCLEASE G; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; ROTENONE; RUTHENIUM RED; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL LINE; CELL SECRETION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME LOCALIZATION; ENZYME MECHANISM; HOMEOSTASIS; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ACTIVE TRANSPORT, CELL NUCLEUS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, NORTHERN; BLOTTING, WESTERN; CADMIUM; CALCIUM; CASPASES; CELL LINE; CHELATING AGENTS; CYTOPLASM; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; ENDODEOXYRIBONUCLEASES; HUMANS; LIVER; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NECROSIS; NF-KAPPA B; ONIUM COMPOUNDS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RNA; ROTENONE; RUTHENIUM RED; TIME FACTORS; UNCOUPLING AGENTS;

EID: 2942527308     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.03.020     Document Type: Article

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