Benzamides and benzamidines as specific inhibitors of epidermal growth factor receptor and v-Src protein tyrosine kinases

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 13, 2004, Pages 3529-3542

  Asano, Toru ^b   Yoshikawa, Tomohiro ^a   Usui, Taikou ^a   Yamamoto, Hiroshi ^a   Yamamoto, Yoshinori ^b   Uehara, Yoshimasa ^c   Nakamura, Hiroyuki ^a  

^a GAKUSHUIN UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

EGFR; Inhibitor; Tyrosine kinase

Indexed keywords

2 AMINO 4,5 DIMETHOXY N (1 PHENYLETHYL)BENZAMIDE; 2 AMINO 4,5 DIMETHOXY N (3 METHOXYPHENYL)BENZAMIDE; 2 AMINO 4,5 DIMETHOXY N (3 METHOXYPHENYL)BENZAMIDINE; 2 AMINO 4,5 DIMETHOXY N (3 TRIFLUOROMETHYLPHENYL)BENZAMIDE; 2 AMINO 4,5 DIMETHOXY N PYRIDIN 2 YLBENZAMIDE; 2 AMINO 4,5 DIMETHOXY N PYRIDIN 3 YLBENZAMIDE; 2 AMINO 4,5 DIMETHOXY N PYRIDIN 4 YLBENZAMIDE; 2 AMINO N (3 BROMOPHENYL) 4,5 DIMETHOXYBENZAMIDE; 2 AMINO N (3 BROMOPHENYL) 4,5 DIMETHOXYBENZAMIDINE; 2 AMINO N (3 CHLOROPHENYL) 4,5 DIMETHOXYBENZAMIDINE; 2 AMINO N (4 CHLORO 3 FLUOROPHENYL) 4,5 BENZAMIDE; 2 AMINO N (4 CHLORO 3 FLUOROPHENYL) 4,5 DIMETHOXYBENZAMIDINE; 2 AMINO N CYCLOHEXYL 4,5 DIMETHOXYBENZAMIDE; 2 NITRO 4,5 DIMETHOXY N PYRIDIN 2 YLBENZAMIDE; 2 NITRO 4,5 DIMETHOXY N PYRIDIN 3 YLBENZAMIDE; 2 NITRO 4,5 DIMETHOXY N PYRIDIN 4 YLBENZAMIDE; 4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6 AMINO N (3 BROMOPHENYL) 2,3,4 TRIMETHOXYBENZAMIDINE; 6 NITRO N (3 BROMOPHENYL) 2,3,4 TRIMETHOXYBENZAMIDINE; BENZAMIDE DERIVATIVE; BENZAMIDINE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VANDETANIB;

ARTICLE; CONCENTRATION RESPONSE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; PROTEINASE INHIBITION; X RAY ANALYSIS;

BENZAMIDES; BENZAMIDINES; CELL LINE, TUMOR; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; HUMANS; HYDROGEN BONDING; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES;

STAPHYLOCOCCUS PHAGE 3A;

EID: 2942521736     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.04.030     Document Type: Article

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