A formal total synthesis of eleutherobin using the ring-closing metathesis (RCM) reaction of a densely functionalized diene as the key step: Investigation of the unusual kinetically controlled RCM stereochemistry

Chemistry - A European Journal

Volumn 12, Issue 1, 2005, Pages 51-62

  Castoldi, Damiano ^a   Caggiano, Lorenzo ^a,c   Panigada, Laura ^a   Sharon, Ofer ^a   Costa, Anna M ^b   Gennari, Cesare ^a  

^a CNR   (Italy)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Antitumor agents; Natural products; Ring closing metathesis; Stereocontrol; Total synthesis

Indexed keywords

ANTITUMOR AGENTS; NATURAL PRODUCTS; RING-CLOSING METATHESIS; STEREOCONTROL; TOTAL SYNTHESIS;

ALCOHOLS; ALDEHYDES; CHEMICAL REACTIONS; ISOMERS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

AROMATIC COMPOUNDS;

DITERPENE; ELEUTHEROBIN; TUBULIN MODULATOR;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; KINETICS; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; CYCLIZATION; DITERPENES; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; TUBULIN MODULATORS;

EID: 29344446565     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/chem.200500749     Document Type: Article

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