Synthesis of novel simplified eleutheside analogues with potent microtubule-stabilizing activity, using ring-closing metathesis as the key-step

Tetrahedron Letters

Volumn 44, Issue 4, 2003, Pages 681-684

  Beumer, Raphael ^a   Bayón, Pau ^a   Bugada, Piergiuliano ^a   Ducki, Sylvie ^b,c   Mongelli, Nicola ^b   Sirtori, Federico Riccardi ^b   Telser, Joachim ^a,d   Gennari, Cesare ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Pharmacia   (Italy)

^c UNIVERSITY OF SALFORD   (United Kingdom)

^d BAYER AG   (Germany)

Author keywords

Allylation; Antitumour compounds; Metathesis; Stereocontrol

Indexed keywords

CHEMICAL COMPOUND; ELEUTHESIDE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; MOLECULAR STABILITY; RING CLOSING METATHESIS; SYNTHESIS;

EID: 0037454986     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02646-1     Document Type: Article

References (46)

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