Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: Synthesis and antiviral activity

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 10-12, 2005, Pages 1763-1774

  Ambrose, Amalraj ^a   Zemlicka, Jiri ^a   Kern, Earl R ^b   Drach, John C ^c   Gullen, Elizabeth ^d   Cheng, Yung Chi ^d  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham and Children's Hospital   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antivirals; EBV; HCMV; Methylenecyclopropane analogues; Phenyl phosphoralaninates; Prodrugs; Pronucleotides; VZV

Indexed keywords

1 [[(2 HYDROXYMETHYL)CYCLOPROPYLIDENE]METHYL] CYTOSINE(METHYLPHENYLPHOSPHORYL)ALANINATE; 1 [[(2 HYDROXYMETHYL)CYCLOPROPYLIDENE]METHYL] THYMINE(METHYLPHENYLPHOSPHORYL)ALANINATE; 1 [[(2 HYDROXYMETHYL)CYCLOPROPYLIDENE]METHYL]CYTOSINE; 1 [[(2 HYDROXYMETHYL)CYCLOPROPYLIDENE]METHYL]THYMINE; 1 [[(HYDROXYMETHYL)CYCLOPROPYLIDENE]METHYL]THYMINE(METHYLPHENYLPHOSPHORYL) ALANINATE; ANTIVIRUS AGENT; CYCLOPROPANE DERIVATIVE; CYTOSINE; NUCLEOTIDE DERIVATIVE; PROPANE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOMEGALOVIRUS; DEPROTECTION REACTION; DRUG POTENCY; DRUG SYNTHESIS; EPSTEIN BARR VIRUS; HEPATITIS B VIRUS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PHOSPHORYLATION; VARICELLA ZOSTER VIRUS;

ANTIVIRAL AGENTS; CELL LINE; CYCLOPROPANES; HUMANS; NUCLEOSIDES; PYRIMIDINES; VIRUS REPLICATION; VIRUSES;

CYTOMEGALOVIRUS; HEPATITIS B VIRUS; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; HUMAN HERPESVIRUS 3; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 5; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 29244482292     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770500266867     Document Type: Article

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