Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference

Pharmaceutical Research

Volumn 22, Issue 12, 2005, Pages 2091-2098

  Matsui, Yumi ^a   Kobayashi, Naoki ^a   Nishikawa, Makiya ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Hydrodynamics based procedure; Liver; P glycoprotein; Plasmid DNA; RNA interference

Indexed keywords

GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1A; MULTIDRUG RESISTANCE PROTEIN 1B; PLASMID DNA; RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; COLON CARCINOMA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MEGADOSE; DRUG TARGETING; FOLLOW UP; GENE SILENCING; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; LIVER; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; VELOCITY; WESTERN BLOTTING;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CELL LINE, TUMOR; DNA; FEMALE; INJECTIONS, INTRAVENOUS; MICE; MICE, INBRED BALB C; P-GLYCOPROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 29244460591     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-005-8178-8     Document Type: Article

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