A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 50, 2005, Pages 17981-17986

  Proszynski, Tomasz J ^a   Klemm, Robin W ^a   Gravert, Maike ^a   Hsu, Peggy P ^a   Gloor, Yvonne ^a   Wagner, Jan ^a   Kozak, Karol ^a   Grabner, Hannes ^a   Walzer, Karen ^a   Bagnat, Michel ^a,b   Simons, Kai ^a   Walch Solimena, Christiane ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Exocytosis; Golgi; Lipid rafts; Saccharomyces cerevisiae; Sorting

Indexed keywords

ACTIN; CELL SURFACE MARKER; ERGOSTEROL; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; PROTEIN; PROTEIN CHS5P; PROTEIN KES1P; PROTEIN RVS161P; PROTEIN VRP1P; SPHINGOLIPID; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CELL SELECTION; CELL SURFACE; CYTOSKELETON; EXOCYTOSIS; GENE IDENTIFICATION; GENETIC SCREENING; GOLGI COMPLEX; LIPID RAFT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; YEAST;

BIOLOGICAL TRANSPORT; CALCIUM-BINDING PROTEINS; DNA MUTATIONAL ANALYSIS; ERGOSTEROL; GENE LIBRARY; GENES, FUNGAL; GREEN FLUORESCENT PROTEINS; MEMBRANE PROTEINS; MUTANT CHIMERIC PROTEINS; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHINGOLIPIDS; TRANS-GOLGI NETWORK; TRANSPORT VESICLES; VESICULAR TRANSPORT PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 29144534564     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509107102     Document Type: Article

References (54)

1. Keller, P. & Simons, K. (1997) J. Cell. Sci. 110, 3001-3009.
2. Ang, A. L., Taguchi, T., Francis, S., Folsch, H., Murrells, L. J., Pypaert, M., Warren, G. & Mellman, I. (2004) J. Cell. Biol. 167, 531-543.
3. Schuck, S. & Simons, K. (2004) J. Cell. Sci. 117, 5955-5964.
4. Rodriguez-Boulan, E., Kreitze, G. & Musch, A. (2005) Nat. Rev. Mol. Cell. Biol. 6, 233-247.
5. Harsay, E. & Bretscher, A. (1995) J. Cell Biol. 131, 297-310.
6. David, D., Sundarababu, S. & Gerst, J. E. (1998) J. Cell Biol. 143, 1167-1182.
7. Harsay, E. & Schekman, R. (2002) J. Cell Biol. 156, 271-285.
8. Gurunathan, S., David, D. & Gerst, J. E. (2002) EMBO J. 21, 602-614.
9. Novick, P., Field, C. & Schekman, R. (1980) Cell 21, 205-215.
10. Newman, A. P. & Ferro-Novick, S. (1987) J. Cell Biol. 105, 1587-1594.
11. Tong, A. H., Evangelista, M., Parsons, A. B., Xu, H., Bader, G. D., Page, N., Robinson, M., Raghibizadeh, S., Hogue, C. W., Bussey, H., et al. (2001) Science 294, 2364-2368.
12. Proszynski, T. J., Simons, K. & Bagnat, M. (2004) Mol. Biol. Cell. 15, 1533-1543.
13. Mumberg, D., Muller, R. & Funk, M. (1994) Nucleic Acids Res. 22, 5767-5768.
14. Han, G., Gable, K., Kohlwein, S. D., Beaudoin, F., Napier, J. A. & Dunn, T. M. (2002) J. Biol. Chem. 277, 35440-35449.
15. Lee, M. C., Hamamoto, S. & Schekman, R. (2002) J. Biol. Chem. 277, 22395-22401.
16. Bagnat, M., Chang, A. & Simons, K. (2001) Mol. Biol. Cell 12, 4129-4138.
17. Santos, B. & Snyder, M. (2003) Eukaryot. Cell 2, 821-825.
18. Santos, B. & Snyder, M. (1997) J. Cell Biol. 136, 95-110.
19. Evangelista, M., Klebl, B. M., Tong, A. H., Webb, B. A., Leeuw, T., Leberer, E., Whiteway, M., Thomas, D. Y. & Boone, C. (2000) J. Cell Biol. 148, 353-362.
20. Geissler, S., Siegers, K. & Schiebel, E. (1998) EMBO J. 17, 952-966.
21. Siegers, K., Waldmann, T., Leroux, M. R., Grein, K., Shevchenko, A., Schiebel, E. & Hartl, F. U. (1999) EMBO J. 18, 75-84.
22. Gstaiger, M., Luke, B., Hess, D., Oakeley, E. J., Wirbelauer, C., Blondel, M., Vigneron, M., Peter, M. & Krek, W. (2003) Science 302, 1208-1212.
23. Giaever, G., Flaherty, P., Kumm, J., Proctor, M., Nislow, C., Jaramillo, D. F., Chu, A. M., Jordan, M. I., Arkin, A. P. & Davis, R. W. (2004) Proc. Natl. Acad. Sci. USA 101, 793-798.
24. Robinson, J. S., Klionsky, D. J., Banta, L. M. & Emr, S. D. (1988) Mol. Cell. Biol. 8, 4936-4948.
25. Rothman, J. H. & Stevens, T. H. (1986) Cell 47, 1041-1051.
26. Bonangelino, C. J., Chavez, E. M. & Bonifacino, J. S. (2002) Mol. Biol. Cell 13, 2486-2501.
27. Wickner, W. (2002) EMBO J. 21, 1241-1247.
28. Marston, A. L., Tham, W. H., Shah, H. & Amon, A. (2004) Science 303, 1367-1370.
29. Guo, W., Roth, D., Walch-Solimena, C. & Novick, P. (1999) EMBO J. 18, 1071-1080.
30. Funato, K., Vallee, B. & Riezman, H. (2002) Biochemistry 41, 15105-15114.
31. Oh, C. S., Toke, D. A., Mandala, S. & Martin, C. E. (1997) J. Biol. Chem. 272, 17376-17384.
32. Obeid, L. M., Okamoto, Y. & Mao, C. (2002) Biochim. Biophys. Acta 1585, 163-171.
33. Athenstaedt, K. & Daum, G. (2000) J. Biol. Chem. 275, 235-240.
34. Munro, S. (1995) EMBO J. 14, 4695-4704.
35. Rayner, J. C. & Pelham, H. R. (1997) EMBO J. 16, 1832-1841.
36. Daum, G., Lees, N. D., Bard, M. & Dickson, R. (1998) Yeast 14, 1471-1510.
37. Umebayashi, K. & Nakano, A. (2003) J. Cell Biol. 161, 1117-1131.
38. Eisenkolb, M., Zenzmaier, C., Leitner, E. & Schneiter, R. (2002) Mol. Biol. Cell. 13, 4414-4428.
39. Bagnat, M., Keranen, S., Shevchenko, A. & Simons, K. (2000) Proc. Natl. Acad. Sci. USA 97, 3254-3259.
40. Munn, A. L., Stevenson, B. J., Geli, M. I. & Riezman, H. (1995) Mol. Biol. Cell 6, 1721-1742.
41. Brizzio, V., Gammie, A. E. & Rose, M. D. (1998) J. Cell Biol. 141, 567-584.
42. Breton, A. M., Schaeffer, J. & Aigle, M. (2001) Yeast 18, 1053-1068.
43. Breton, A. M. & Aigle, M. (1998) Curr. Genet. 34, 280-286.
44. Balguerie, A., Bagnat, M., Bonneu, M., Aigle, M. & Breton, A. M. (2002) Eukaryot. Cell. 1, 1021-1031.
45. Peter, B. J., Kent, H. M., Mills, I. G., Vallis, Y., Butler, P. J., Evans, P. R. & McMahon, H. T. (2004) Science 303, 495-499.
46. Rozelle, A. L., Machesky, L. M., Yamamoto, M., Driessens, M. H., Insall, R. H., Roth, M. G., Luby-Phelps, K., Marriott, G., Hall, A. & Yin, H. L. (2000) Curr. Biol. 10, 311-320.
47. Rodriguez-Pena, J. M., Rodriguez, C., Alvarez, A., Nombela, C. & Arroyo, J. (2002) J. Cell Sci. 115, 2549-2558.
48. Tong, A. H., Lesage, G., Bader, G. D., Ding, H., Xu, H., Xin, X., Young, J., Berriz, G. F., Brost, R. L., Chang, M., et al. (2004) Science 303, 808-813.
49. Im, Y. J., Raychaudhuri, S., Prinz, W. A. & Hurley, J. H. (2005) Nature 437, 154-158.
50. Li, X., Rivas, M. P., Fang, M., Marchena, J., Mehrotra, B., Chaudhary, A., Feng, L., Prestwich, G. D. & Bankaitis, V. A. (2002) J. Cell Biol. 157, 63-77.
51. Godi, A., Di Campli, A., Konstantakopoulos, A., Di Tullio, G., Alessi, D. R., Kular, G. S., Daniele, T., Marra, P., Lucocq, J. M. & De Matteis, M. A. (2004) Nat. Cell Biol. 6, 393-404.
52. Vieira, O. V., Verkade, P., Manninen, A. & Simons, K. (2005) J. Cell Biol. 170, 521-526.
53. Romero, P. A., Lussier, M., Veronneau, S., Sdicu, A. M., Herscovics, A. & Bussey, H. (1999) Glycobiology 9, 1045-1051.
54. Bagnat, M. & Simons, K. (2002) Biol. Chem. 383, 1475-1480.