Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide- induced outwardly rectifying potassium current and interleukin-1β production in cultured rat microglia

Journal of Neurochemistry

Volumn 70, Issue 6, 1998, Pages 2357-2368

  Caggiano, Anthony O ^a   Kraig, Richard P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Eicosanoids; Gilosis; Inflammation; Patch clamp; Prostaglandins

Indexed keywords

4 AMINOPYRIDINE; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; CD11B ANTIGEN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; ENCEPHALITIS; INFLAMMATION; LEUKOCYTE ACTIVATION; MICROGLIA; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; METABOLISM; NEWBORN; PATCH CLAMP; WISTAR RAT;

ANIMALIA;

4-AMINOPYRIDINE; ANIMALS; ANIMALS, NEWBORN; CELL DEATH; CELLS, CULTURED; DINOPROSTONE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGE-1 ANTIGEN; MICROGLIA; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, WISTAR;

EID: 0031596838     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70062357.x     Document Type: Article

References (62)

1. Akaike A., Kaneko S., Tamura Y., Nakata N., Shiomi H., Ushikubi F., and Narumiya S. (1994) Prostaglandin E2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res. 663, 237-243.
2. Aktan S., Aykut C., Yegen B. C., Okar I., Ozkutlu U., and Ercan S. (1993) The effect of nordihydroguaiaretic acid on leukotriene C4 and prostaglandin E2 production following different reperfusion periods in rat brain after forebrain ischemia correlated with morphological changes. Prostaglandins Leukot. Essent. Fatty Acids 49, 633-641.
3. Banati R. B., Hoppe D., Gottmann K., Kreutzberg G. W., and Kettenmann H. (1991) A subpopulation of bone marrow-derived macrophage-like cells shares a unique ion channel pattern with microglia. J. Neurosci. Res. 30, 593-600.
4. Bingisser R., Stey C., Weller M., Groscurth P., Russi E., and Frei K. (1996) Apoptosis in human alveolar macrophages is induced by endotoxin and is modulated by cytokines. Am. J. Respir. Cell Mol. Biol. 15, 64-70.
5. Bonney R. J. and Davies P. (1984) Possible autoregulatory functions of the secretory products of mononuclear phagocytes. Contemp. Top. Immunobiol. 13, 199-223.
6. Bottenstein J. E. and Sato G. H. (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc. Natl. Acad. Sci. USA 76, 514-517.
7. Caggiano A. O. and Kraig R. P. (1996) Eicosanoids and nitric oxide influence induction of reactive gliosis from spreading depression in microglia but not astrocytes. J. Comp. Neurol. 369, 93-108.
8. Caggiano A. O., Breder C. D., and Kraig R. P. (1996) Long-term elevation of cyclooxygenase-2, but not lipoxygenase, in regions synaptically distant from spreading depression. J. Comp. Neurol. 376, 447-462.
9. Cazevieille C., Muller A., and Bonne C. (1993) Prostacyclin (PGI2) protects rat cortical neurons in culture against hypoxia/reoxygenation and glutamate-induced injury. Neurosci. Lett. 160, 106-108.
10. Chiu S. Y. and Wilson G. F. (1989) The role of potassium channels in Schwann cell proliferation in Wallerian degeneration of explant rabbit sciatic nerves. J. Physiol. (Lond.) 408, 199-222.
11. Dewitt D. S., Kong D. L., Lyeth B. G., Jenkins L. W., Hayes R. L., Woolen E. D., and Prough D. S. (1988) Experimental traumatic brain injury elevates brain prostaglandin E2 and thromboxane B2 levels in rats. J. Neurotrauma 5, 303-313.
12. Douglas W. W. (1975) Pharmacologic Basis of Therapeutics, p. 664. Macmillan, New York.
13. Ellis E. F., Wright K. F., Wei E. P., and Kontos H. A. (1981) Cyclooxygenase products of arachidonic acid metabolism in cat cerebral cortex after experimental concussive brain injury. J. Neurochem. 37, 892-896.
14. Ellis E. F., Police R. J., Rice L. Y., Grabeel M., and Holt S. (1989) Increased plasma PGE2, 6-keto-PGF1 alpha, and 12-HETE levels following experimental concussive brain injury. J. Neurotrauma 6, 31-37.
15. Ferrari D., Chiozzi P., Falzoni S., Hanau S., and Di Virgilio F. (1997) Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 185, 579-582.
16. + channel profile of microglia at immunologically defined functional states. Neuroscience 64, 183-191.
17. Funk C. D. (1993) Molecular biology in the eicosanoid field. Prog. Nucleic Acid Res. 45, 67-98.
18. Furlow T. W. Jr. and Hallenbeck J. M. (1978) Indomethacin prevents impaired perfusion of the dog's brain after global ischemia. Stroke 9, 591-594.
19. + channel block. J. Neurosci. 16, 2659-2670.
20. Gehrmann J., Mies G., Bonnekoh P., Banati R., Iijima T., Kreutzberg G. W., and Hossmann K. A. (1993) Microglial reaction in the rat cerebral cortex induced by cortical spreading depression. Brain Pathol. 3, 11-17.
21. Giulian D. and Baker T. J. (1986) Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 6, 2163-2178.
22. Goetzl E. J., An S., and Smith W. L. (1995) Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases. FASEB J. 9, 1051-1058.
23. Graeber M. B., Streit W. J., and Kreutzberg G. W. (1988a) Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells. J. Neurosci. Res. 21, 18-24.
24. Graeber M. B., Tetzlaff W., Streit W. J., and Kreutzberg G. W. (1988b) Microglial cells but not astrocytes undergo mitosis following rat facial nerve axotomy. Neurosci. Lett. 85, 317-321.
25. Hetier E., Ayala J., Denefle P., Bousseau A., Rouget P., Mallat M., and Prochiantz A. (1988) Brain macrophages synthesize interleukin-1 and interleukin-1 mRNAs in vitro. J. Neurosci. Res. 21, 391-397.
26. Illes P., Nörenberg W., and Gebicke-Haerter P. J. (1996) Molecular mechanisms of microglial activation. B. Voltage- and purino-ceptor-operated channels in microglia. Neurochem. Int. 29, 13-24.
27. Imamura K., Suzumura A., Sawada M., Marunouchi T., and Takahashi A. (1991) Functional and immunohistochemical studies of cultured rat microglia. Rinsho Shinkeigaku 31, 127-134.
28. Kettenmann H., Hoppe D., Gottmann K., Banati R., and Kreutzberg G. (1990) Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. J. Neurosci. Res. 26, 278-287.
29. Kiefer R., Lindholm D., and Kreutzberg G. W. (1993) Interleukin-6 and transforming growth factor-beta 1 mRNAs are induced in rat facial nucleus following motoneuron axotomy. Eur. J. Neurosci. 5, 775-781.
30. Kunkel S. L., Spengler M., May M. A., Spengler R., Larrick J., and Remick D. (1988) Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression. J. Biol. Chem. 263, 5380-5384.
31. Lascola C. D. and Kraig R. P. (1996) Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology. J. Neurosci. 16, 2532-2545.
32. Levison S.W. and McCarthy K. D. (1991) Characterization and partial purification of AIM: a plasma protein that induces rat cerebral type 2 astroglia from bipotential glial progenitors. J. Neurochem. 57, 782-794.
33. Luo Y. and Vallano M. L. (1995) Arachidonic acid, but not sodium nitroprusside, stimulates presynaptic protein kinase C and phosphorylation of GAP-43 in rat hippocampal slices and synaptosomes. J. Neurochem. 64, 1808-1818.
34. MacFarlane S. N. and Sontheimer H. (1997) Electrophysiological changes that accompany reactive gliosis in vitro. J. Neurosci. 17, 7316-7329.
35. McGeer P. L. and McGeer E. G. (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Brain Res. Rev. 21, 195-218.
36. McGeer P. L., Kawamata T., Walker D. G., Akiyama H., Tooyama I., and McGeer E. G. (1993) Microglia in degenerative neurological disease. Glia 7, 84-92.
37. Medana I. M., Hunt N. H., and Chaudhri G. (1997) Tumor necrosis factor-alpha expression in the brain during fatal murine cerebral malaria: evidence for production by microglia and astrocytes. Am. J. Pathol. 150, 1473-1486.
38. Minghetti L., Nicolini A., Polazzi E., Creminon C., Maclouf J., and Levi G. (1997) Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors. Glia 19, 152-160.
39. Morioka T. and Streit W. J. (1991) Expression of immunomolecules on microglial cells following neonatal sciatic nerve axotomy. J. Neuroimmunol. 35, 21-30.
40. Moskowitz M. A., Nozaki K., and Kraig R. P. (1993) Neocortical spreading depression provokes the expression of c-Fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms. J. Neurosci. 13, 1167-1177.
41. Needleman P., Turk J., Jakschik B. A., Morrison A. R., and Lefkowith J.B. (1986) Arachidonic acid metabolism. Annu. Rev. Biochem. 55, 69-102.
42. + outward current in cultured rat microglia. Neurosci. Lett. 147, 171-174.
43. Nörenberg W., Gebicke-Haerter P. J., and Illes P. (1994) Voltage-dependent potassium channels in activated rat microglia. J. Physiol. (Lond.) 475, 15-32.
44. Paakkari I. and Lindsberg P. (1995) Nitric oxide in the central nervous system. Ann. Med. 27, 369-377.
45. i. Neuroreport 6, 193-196.
46. Piomelli D. (1993) Arachidonic acid in cell signaling. Curr. Opin. Cell Biol. 5, 274-280.
47. Puro D. G., Roberge F., and Chan C. C. (1989) Retinal glial cell proliferation and ion channels: a possible link. Invest. Ophthalmoi Vis. Sci. 30, 521-529.
48. Sawada M., Kondo N., Suzumura A., and Marunouchi T. (1989) Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Res. 491, 394-397.
49. - channels and their involvement in proliferation of rat microglial cells. Glia 17, 225-236.
50. Schluter D., Kaefer N., Hof H., Wiestler O. D., and Deckert-Schluter M. (1997) Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain. Am. J. Pathol. 150, 1021-1035.
51. Shohami E., Shapira Y., Sidi A., and Cotev S. (1987) Head injury induces increased prostaglandin synthesis in rat brain. J. Cereb. Blood Flow Metab. 7, 58-63.
52. Stewart R. R. (1994) Membrane properties of microglial cells isolated from the leech central nervous system. Proc. R. Soc. Lond. [Biol.] 255, 201-208.
53. Théry C., Dobbertin A., and Mallat M. (1994) Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a β-adrenergic agonist. Glia 11, 383-386.
54. Van Dam A. M., Brouns M., Man-A-Hing W., and Berkenbosch F. (1993) Immunocytochemical detection of prostaglandin E2 in microvasculature and in neurons of rat brain after administration of bacterial endotoxin. Brain Res. 613, 331-336.
55. Visentin S., Agresti C., Patrizio M., and Levi G. (1995 ) Ion channels in rat microglia and their different sensitivity to lipopolysaccharide and interferon-gamma. J. Neurosci. Res. 42, 439-451.
56. Williams T. E., Ayala A., and Chaudry I. H. (1997) Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release. J. Surg. Res. 70, 113-118.
57. Wong G. H., Bartlett P. F., Clark-Lewis I., Battye F., and Schrader J. W. (1984) Inducible expression of H-2 and Ia antigens on brain cells. Nature 310, 688-691.
58. Woodroofe M. N., Hayes G. M., and Cuzner M. L. (1989) Fc receptor density, MHC antigen expression and superoxide production are increased in interferon-gamma-treated microglia isolated from adult rat brain. Immunology 68, 421-426.
59. Yamagata K., Andreasson K. I., Kaufmann W. E., Barnes C. A., and Worley P. F. (1993) Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11, 371-386.
60. Yokochi T., Kato Y., Sugiyama T., Koide N., Morikawa A., Jiang G. Z., Kawai M., Yoshida T., Fukada M., and Takahashi K. (1996) Lipopolysaccharide induces apoptotic cell death of B memory cells and regulates B cell memory in antigen-nonspecific manner. FEMS Immunol. Med. Microbiol. 15, 1-8.
61. Young J. D., Unkeless J. C., Young T. M., Mauro A., and Cohn Z. A. (1983) Role for mouse macrophage IgG Fc receptor as ligand-dependent ion channel. Nature 306, 186-189.
62. Zielasek J., Tausch M., Toyka K. V., and Hartung H. P. (1992) Production of nitrite by neonatal rat microglial cells/brain macrophages. Cell. Immunol. 141, 111-120.