메뉴 건너뛰기




Volumn 129, Issue 2, 2005, Pages 251-259

The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice

Author keywords

Angiogenesis inhibitor; VEGF; Wound healing; ZD6474

Indexed keywords

VANDETANIB; VASCULOTROPIN;

EID: 29144510498     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2005.05.006     Document Type: Article
Times cited : (35)

References (40)
  • 1
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • J. Folkman Role of angiogenesis in tumor growth and metastasis Semin. Oncol. 29 2002 15
    • (2002) Semin. Oncol. , vol.29 , pp. 15
    • Folkman, J.1
  • 2
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • D. Hanahan, J. Folkman Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 1996 353
    • (1996) Cell , vol.86 , pp. 353
    • Hanahan, D.1    Folkman, J.2
  • 3
    • 0033650988 scopus 로고    scopus 로고
    • New paradigms for the treatment of cancer: The role of anti-angiogenesis agents
    • J.M. Cherrington, L.M. Strawn, L.K. Shawver New paradigms for the treatment of cancer The role of anti-angiogenesis agents Adv. Cancer Res. 79 2000 1
    • (2000) Adv. Cancer Res. , vol.79 , pp. 1
    • Cherrington, J.M.1    Strawn, L.M.2    Shawver, L.K.3
  • 4
    • 0033556287 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases
    • M. Meyer, M. Clauss, A. Lepple-Wienhues A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases EMBO J. 18 1999 363
    • (1999) EMBO J. , vol.18 , pp. 363
    • Meyer, M.1    Clauss, M.2    Lepple-Wienhues, A.3
  • 5
    • 0035793623 scopus 로고    scopus 로고
    • Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). a reassessment using novel receptor-specific vascular endothelial growth factor mutants
    • H. Gille, J. Kowalski, B. Li Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants J. Biol. Chem. 276 2001 3222
    • (2001) J. Biol. Chem. , vol.276 , pp. 3222
    • Gille, H.1    Kowalski, J.2    Li, B.3
  • 6
    • 0035980051 scopus 로고    scopus 로고
    • Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively
    • H. Zeng, S. Sanyal, D. Mukhopadhyay Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively J. Biol. Chem. 276 2001 32714
    • (2001) J. Biol. Chem. , vol.276 , pp. 32714
    • Zeng, H.1    Sanyal, S.2    Mukhopadhyay, D.3
  • 7
    • 0032852528 scopus 로고    scopus 로고
    • Molecular and biological properties of vascular endothelial growth factor
    • N. Ferrara Molecular and biological properties of vascular endothelial growth factor J. Molec. Med. 77 1999 527
    • (1999) J. Molec. Med. , vol.77 , pp. 527
    • Ferrara, N.1
  • 8
    • 0030713446 scopus 로고    scopus 로고
    • Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1- mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells
    • A. Damert, E. Ikeda, W. Risau Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells Biochem. J. 327 1997 419
    • (1997) Biochem. J. , vol.327 , pp. 419
    • Damert, A.1    Ikeda, E.2    Risau, W.3
  • 9
    • 0032941747 scopus 로고    scopus 로고
    • Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements
    • J.A. Dibbens, D.L. Miller, A. Damert, W. Risau, M.A. Vadas, G.J. Goodall Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements Molec. Biol. Cell 10 1999 907
    • (1999) Molec. Biol. Cell , vol.10 , pp. 907
    • Dibbens, J.A.1    Miller, D.L.2    Damert, A.3    Risau, W.4    Vadas, M.A.5    Goodall, G.J.6
  • 10
    • 0028822834 scopus 로고
    • Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumor angiogenesis
    • J. Rak, Y. Mitsuhashi, L. Bayko Mutant ras oncogenes upregulate VEGF/VPF expression Implications for induction and inhibition of tumor angiogenesis Cancer Res. 55 1995 4575
    • (1995) Cancer Res. , vol.55 , pp. 4575
    • Rak, J.1    Mitsuhashi, Y.2    Bayko, L.3
  • 11
    • 0031985127 scopus 로고    scopus 로고
    • Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src
    • L.M. Ellis, C.A. Staley, W. Liu Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src J. Biol. Chem. 273 1998 1052
    • (1998) J. Biol. Chem. , vol.273 , pp. 1052
    • Ellis, L.M.1    Staley, C.A.2    Liu, W.3
  • 12
    • 0030834249 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity
    • D. Mukhopadhyay, B. Knebelmann, H.T. Cohen, S. Ananth, V.P. Sukhatme The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity Molec. Cell. Biol. 17 1997 5629
    • (1997) Molec. Cell. Biol. , vol.17 , pp. 5629
    • Mukhopadhyay, D.1    Knebelmann, B.2    Cohen, H.T.3    Ananth, S.4    Sukhatme, V.P.5
  • 13
    • 0034235047 scopus 로고    scopus 로고
    • Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression
    • L. Zhang, D. Yu, M. Hu Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression Cancer Res. 60 2000 3655
    • (2000) Cancer Res. , vol.60 , pp. 3655
    • Zhang, L.1    Yu, D.2    Hu, M.3
  • 14
    • 0028090642 scopus 로고
    • Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms
    • K.H. Plate, G. Breier, H.A. Weich, H.D. Mennel, W. Risau Vascular endothelial growth factor and glioma angiogenesis Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms Int. J. Cancer 59 1994 520
    • (1994) Int. J. Cancer , vol.59 , pp. 520
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Mennel, H.D.4    Risau, W.5
  • 15
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Y. Takahashi, Y. Kitadai, C.D. Bucana, K.R. Cleary, L.M. Ellis Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer Cancer Res. 55 1995 3964
    • (1995) Cancer Res. , vol.55 , pp. 3964
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 16
    • 0344109584 scopus 로고    scopus 로고
    • Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients
    • U. Eppenberger, W. Kueng Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients J. Clin. Oncol. 16 1998 3129
    • (1998) J. Clin. Oncol. , vol.16 , pp. 3129
    • Eppenberger, U.1    Kueng, W.2
  • 17
    • 0033063774 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its inhibition in cancer therapy
    • J.R. Woodburn The epidermal growth factor receptor and its inhibition in cancer therapy Pharmacol. Ther. 82 1999 241
    • (1999) Pharmacol. Ther. , vol.82 , pp. 241
    • Woodburn, J.R.1
  • 21
    • 0034896362 scopus 로고    scopus 로고
    • Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
    • F. Ciardiello, R. Caputo, R. Bianco Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor Clin. Cancer Res. 7 2001 1459
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1459
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3
  • 22
    • 19244366949 scopus 로고    scopus 로고
    • Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
    • J. Baselga, D. Pfister, M.R. Cooper Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin J. Clin. Oncol. 18 2000 904
    • (2000) J. Clin. Oncol. , vol.18 , pp. 904
    • Baselga, J.1    Pfister, D.2    Cooper, M.R.3
  • 23
    • 0033757346 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
    • F. Ciardiello Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents Drugs 60 2000 25
    • (2000) Drugs , vol.60 , pp. 25
    • Ciardiello, F.1
  • 24
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • R. Kerbel, J. Folkman Clinical translation of angiogenesis inhibitors Nat. Rev. Cancer. 2 2002 727
    • (2002) Nat. Rev. Cancer. , vol.2 , pp. 727
    • Kerbel, R.1    Folkman, J.2
  • 25
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
    • S.R. Wedge, D.J. Ogilvie, M. Dukes ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration Cancer Res. 62 2002 4645
    • (2002) Cancer Res. , vol.62 , pp. 4645
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3
  • 26
    • 0037115405 scopus 로고    scopus 로고
    • ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
    • F. Carlomagno, D. Vitagliano, T. Guida ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases Cancer Res. 62 2002 7284
    • (2002) Cancer Res. , vol.62 , pp. 7284
    • Carlomagno, F.1    Vitagliano, D.2    Guida, T.3
  • 27
    • 0000162958 scopus 로고    scopus 로고
    • Phase I pharmacokinetics and biological study of the angiogenesis inhibitor, ZD6474, in patients with solid tumors
    • R. Basser, H. Hurwitz, A. Barge Phase I pharmacokinetics and biological study of the angiogenesis inhibitor, ZD6474, in patients with solid tumors Proc. Am. Soc. Clin. Oncol. 37 2001 21
    • (2001) Proc. Am. Soc. Clin. Oncol. , vol.37 , pp. 21
    • Basser, R.1    Hurwitz, H.2    Barge, A.3
  • 28
    • 0141542201 scopus 로고    scopus 로고
    • A Phase I study of an oral VEGF receptor tyrosine kinase inhibitor ZD6474, in Japanese patients with solid tumors
    • H. Minami, H. Ebi, M. Tahara A Phase I study of an oral VEGF receptor tyrosine kinase inhibitor ZD6474, in Japanese patients with solid tumors Proc. Am. Soc. Clin. Oncol. 22 2003 194 (abst 778)
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 194
    • Minami, H.1    Ebi, H.2    Tahara, M.3
  • 29
    • 0029803590 scopus 로고    scopus 로고
    • Angiogenesis inhibitor TNP-470 prevents implanted liver metastases after partial hepatectomy in an experimental model without impairing wound healing
    • H. Tanaka, H. Taniguchi, T. Mugitani Angiogenesis inhibitor TNP-470 prevents implanted liver metastases after partial hepatectomy in an experimental model without impairing wound healing Br. J. Surg. 83 1996 1444
    • (1996) Br. J. Surg. , vol.83 , pp. 1444
    • Tanaka, H.1    Taniguchi, H.2    Mugitani, T.3
  • 31
    • 0034212417 scopus 로고    scopus 로고
    • The angiogenesis inhibitor, endostatin, does not affect murine cutaneous wound healing
    • A.C. Berger, A.L. Feldman, M.F. Gnant The angiogenesis inhibitor, endostatin, does not affect murine cutaneous wound healing J. Surg. Res. 91 2000 26
    • (2000) J. Surg. Res. , vol.91 , pp. 26
    • Berger, A.C.1    Feldman, A.L.2    Gnant, M.F.3
  • 32
    • 0035679574 scopus 로고    scopus 로고
    • CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism
    • L.B. Nanney, B.D. Wamil, J. Whitsitt CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism Angiogenesis 4 2001 61
    • (2001) Angiogenesis , vol.4 , pp. 61
    • Nanney, L.B.1    Wamil, B.D.2    Whitsitt, J.3
  • 33
    • 0036294343 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated angiogenesis inhibition and postoperative wound healing in rats
    • C.D. Roman, H. Choy, L. Nanney Vascular endothelial growth factor-mediated angiogenesis inhibition and postoperative wound healing in rats J. Surg. Res. 105 2002 43
    • (2002) J. Surg. Res. , vol.105 , pp. 43
    • Roman, C.D.1    Choy, H.2    Nanney, L.3
  • 34
    • 0034655182 scopus 로고    scopus 로고
    • PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
    • J.M. Wood, G. Bold, E. Buchdunger PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration Cancer Res. 60 2000 2178
    • (2000) Cancer Res. , vol.60 , pp. 2178
    • Wood, J.M.1    Bold, G.2    Buchdunger, E.3
  • 38
    • 0026857893 scopus 로고
    • Effects of freezing on mechanical properties of rat skin
    • T.L. Foutz, E.A. Stone, C.F. Abrams Jr Effects of freezing on mechanical properties of rat skin Am. J. Vet. Res. 53 1992 788
    • (1992) Am. J. Vet. Res. , vol.53 , pp. 788
    • Foutz, T.L.1    Stone, E.A.2    Abrams Jr., C.F.3
  • 39
    • 0025740211 scopus 로고
    • Freezing for postmortal storage influences the biomechanical properties of linear skin wounds
    • A. Quirinia, A. Viidik Freezing for postmortal storage influences the biomechanical properties of linear skin wounds J. Biomech. 24 1991 819
    • (1991) J. Biomech. , vol.24 , pp. 819
    • Quirinia, A.1    Viidik, A.2
  • 40
    • 0037134709 scopus 로고    scopus 로고
    • Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us
    • L. Hlatky, P. Hahnfeldt, J. Folkman Clinical application of antiangiogenic therapy Microvessel density, what it does and doesn't tell us J. Natl. Cancer Inst. 94 2002 883
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 883
    • Hlatky, L.1    Hahnfeldt, P.2    Folkman, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.