A computational model of mitochondrial AZT metabolism

Biochemical Journal

Volumn 392, Issue 2, 2005, Pages 363-373

  Bradshaw, Patrick C ^a   Li, Jiaxin ^a   Samuels, David C ^a  

^a VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

Author keywords

Antiviral toxicity; AZT; Deoxynucleotide metabolism; Mitochondrial DNA; Polymerase ; Zidovudine

Indexed keywords

CELLS; COMPUTATIONAL METHODS; COMPUTER SIMULATION; DNA; MATHEMATICAL MODELS; TOXICITY;

ANTIVIRAL TOXICITY; AZT; DEOXYNUCLEOTIDE METABOLISM; MITOCHONDRIAL DNA; POLYMERASE Γ; ZIDOVUDINE;

METABOLISM;

DEOXYRIBONUCLEOTIDE; MITOCHONDRIAL DNA; THYMIDINE TRIPHOSPHATE; ZIDOVUDINE;

ARTICLE; CELL TYPE; COMPUTATIONAL FLUID DYNAMICS; COMPUTER PREDICTION; COMPUTER SIMULATION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG METABOLISM; DRUG TRANSPORT; DRUG UPTAKE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOSIS INDEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; COMPUTER SIMULATION; DNA REPLICATION; DNA, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; RATS; ZIDOVUDINE;

EID: 29144503030     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050749     Document Type: Article

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