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Volumn 10, Issue 12, 1996, Pages 1361-1367

The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites

Author keywords

Antiviral therapy; HIV infection; Zidovudine phosphorylation

Indexed keywords

ACICLOVIR; COTRIMOXAZOLE; DOSULEPIN; DRUG METABOLITE; FLUCONAZOLE; RANITIDINE; TEMAZEPAM; ZIDOVUDINE; ZIDOVUDINE 5' TRIPHOSPHATE;

EID: 0029768927     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199610000-00008     Document Type: Article
Times cited : (77)

References (26)
  • 1
    • 0029651152 scopus 로고
    • A year of transformation in HIV/AIDS
    • Montaner JSG, Schechter MT: A year of transformation in HIV/AIDS. Lancet 1995, 346 (suppl):12.
    • (1995) Lancet , vol.346 , Issue.SUPPL. , pp. 12
    • Montaner, J.S.G.1    Schechter, M.T.2
  • 2
    • 0023266214 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Fischl MA, Richman DD, Grieco MH, et al.: The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. N Engl J Med 1987, 317:185-191.
    • (1987) N Engl J Med , vol.317 , pp. 185-191
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3
  • 3
    • 0023268502 scopus 로고
    • The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Richman DD, Fischl MA, Grieco MH, et al.: The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. N Engl J Med 1987, 317:192-197.
    • (1987) N Engl J Med , vol.317 , pp. 192-197
    • Richman, D.D.1    Fischl, M.A.2    Grieco, M.H.3
  • 4
    • 0025053184 scopus 로고
    • A pilot study of low-dose zidovudine in human immunodeficiency virus infection
    • Collier AC, Bozzette S, Coombs RW, et al.: A pilot study of low-dose zidovudine in human immunodeficiency virus infection. N Engl J Med 1990, 323:1015-1021.
    • (1990) N Engl J Med , vol.323 , pp. 1015-1021
    • Collier, A.C.1    Bozzette, S.2    Coombs, R.W.3
  • 5
    • 0026567287 scopus 로고
    • Double blind dose response study of zidovudine in AIDS and advanced HIV infection
    • Norrby SR, Gotzsche PC, Melander H, et al.: Double blind dose response study of zidovudine in AIDS and advanced HIV infection. BMJ 1992, 304:13-17.
    • (1992) BMJ , vol.304 , pp. 13-17
    • Norrby, S.R.1    Gotzsche, P.C.2    Melander, H.3
  • 6
    • 0023475103 scopus 로고
    • 3′-Azido-3′-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase
    • St Clair MH, Richards CA, Spector T, et al.: 3′-Azido-3′-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase. Antimicrob Agents Chemother 1987, 31:1972-1977.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 1972-1977
    • St Clair, M.H.1    Richards, C.A.2    Spector, T.3
  • 7
    • 0028227986 scopus 로고
    • Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity
    • Barry M, Howe JL, Back DJ, et al.: Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity. Br J Clin Pharmacol 1994, 37:7-12.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 7-12
    • Barry, M.1    Howe, J.L.2    Back, D.J.3
  • 8
    • 0026742359 scopus 로고
    • Pharmacokinetics of zidovudine phosphorylation in patients infected with the human immunodeficiency virus
    • Stretcher BN, Pesce AJ, Hurtubise PE, Frame PT: Pharmacokinetics of zidovudine phosphorylation in patients infected with the human immunodeficiency virus. Ther Drug Monit 1992, 14:281-285.
    • (1992) Ther Drug Monit , vol.14 , pp. 281-285
    • Stretcher, B.N.1    Pesce, A.J.2    Hurtubise, P.E.3    Frame, P.T.4
  • 9
    • 0025828521 scopus 로고
    • A reduced dose of zidovudine in patients with AIDS
    • Collier AC, Tartaglione T, Corey L: A reduced dose of zidovudine in patients with AIDS. N Engl J Med 1991, 324:994-996.
    • (1991) N Engl J Med , vol.324 , pp. 994-996
    • Collier, A.C.1    Tartaglione, T.2    Corey, L.3
  • 10
    • 0028225227 scopus 로고
    • Correlates of zidovudine phosphorylation with markers of HIV disease progression and drug toxicity
    • Stretcher BN, Pesce AJ, Frame PT, Greenberg KA, Stein DS: Correlates of zidovudine phosphorylation with markers of HIV disease progression and drug toxicity. AIDS 1994, 8:763-769.
    • (1994) AIDS , vol.8 , pp. 763-769
    • Stretcher, B.N.1    Pesce, A.J.2    Frame, P.T.3    Greenberg, K.A.4    Stein, D.S.5
  • 12
    • 0026446188 scopus 로고
    • Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure
    • Slusher JT, Kuwahara SK, Hamzeh FM, Lewis LD, Kornhauser DM, Lietman PS: Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure. Antimicrob Agents Chemother 1992, 36:2473-2477.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 2473-2477
    • Slusher, J.T.1    Kuwahara, S.K.2    Hamzeh, F.M.3    Lewis, L.D.4    Kornhauser, D.M.5    Lietman, P.S.6
  • 13
    • 0025997616 scopus 로고
    • Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells
    • Törnevik Y, Jacobsson B, Britton S, Eriksson S: Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells. AIDS Res Hum Retroviruses 1991, 7:751-759.
    • (1991) AIDS Res Hum Retroviruses , vol.7 , pp. 751-759
    • Törnevik, Y.1    Jacobsson, B.2    Britton, S.3    Eriksson, S.4
  • 14
    • 0028308785 scopus 로고
    • Zidovudine phosphorylation in HIV-infected patients and seronegative volunteers
    • Barry M, Wild M, Veal G, et al.: Zidovudine phosphorylation in HIV-infected patients and seronegative volunteers. AIDS 1994, 8:F1-F5.
    • (1994) AIDS , vol.8
    • Barry, M.1    Wild, M.2    Veal, G.3
  • 15
    • 0027939485 scopus 로고
    • Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells
    • Veal GJ, Wild MJ, Barry MG, Back DJ: Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells. Br J Clin Pharmacol 1994, 38:323-328.
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 323-328
    • Veal, G.J.1    Wild, M.J.2    Barry, M.G.3    Back, D.J.4
  • 16
    • 0028232638 scopus 로고
    • Pharmacokinetics of zidovudine phosphorylation in peripheral mononuclear cells from patients infected with human immunodeficiency virus
    • Stretcher BN, Pesce AJ, Frame PT, et al.: Pharmacokinetics of zidovudine phosphorylation in peripheral mononuclear cells from patients infected with human immunodeficiency virus. Antimicrob Agents Chemother 1994, 38:1541-1547.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1541-1547
    • Stretcher, B.N.1    Pesce, A.J.2    Frame, P.T.3
  • 17
    • 0026007216 scopus 로고
    • A method for the quantification of intracellular zidovudine nucleotides
    • Kuster H, Vogt M, Joos B, et al.: A method for the quantification of intracellular zidovudine nucleotides. J Infect Dis 1991, 164:773-776.
    • (1991) J Infect Dis , vol.164 , pp. 773-776
    • Kuster, H.1    Vogt, M.2    Joos, B.3
  • 18
    • 0025743488 scopus 로고
    • Concentrations of phosphorylated zidovudine (ZDV) in patient leucocytes do not correlate with ZDV dose or plasma concentration
    • Stretcher BN, Pesce AJ, Murray JA, et al.: Concentrations of phosphorylated zidovudine (ZDV) in patient leucocytes do not correlate with ZDV dose or plasma concentration. Ther Drug Monit 1991, 13:335-341.
    • (1991) Ther Drug Monit , vol.13 , pp. 335-341
    • Stretcher, B.N.1    Pesce, A.J.2    Murray, J.A.3
  • 19
    • 0022996630 scopus 로고
    • Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase
    • Furman PA, Fyfe JA, St Clair MH, et al.: Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci USA 1986, 83:8333-8337.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8333-8337
    • Furman, P.A.1    Fyfe, J.A.2    St Clair, M.H.3
  • 20
    • 0028332852 scopus 로고
    • 3′-azido-3′-deoxythymidine potentially inhibits protein glycosylation
    • Hall ET, Yan J-P, Melancon P, et al.: 3′-azido-3′-deoxythymidine potentially inhibits protein glycosylation. J Biol Chem 1994, 269:14355-14358.
    • (1994) J Biol Chem , vol.269 , pp. 14355-14358
    • Hall, E.T.1    Yan, J.-P.2    Melancon, P.3
  • 21
    • 0029157098 scopus 로고
    • 3′-Azidothymidine (zidovudine) inhibits glycosylation and dramatically alters glycosphingolipid synthesis in whole cells at clinically relevant concentrations
    • Van J-P, Ilsley DD, Frohlich C, et al.: 3′-Azidothymidine (zidovudine) inhibits glycosylation and dramatically alters glycosphingolipid synthesis in whole cells at clinically relevant concentrations. J Biol Chem 1995, 270:22836-22841.
    • (1995) J Biol Chem , vol.270 , pp. 22836-22841
    • Van, J.-P.1    Ilsley, D.D.2    Frohlich, C.3
  • 22
    • 0028920558 scopus 로고
    • Cytotoxicity of 3′-azido-3′-deoxythymidine correlates with 3′-azidothymidine-5′-monophosphate (AZTMP) levels, whereas anti human immunodeficiency virus (HIV) activity correlates with 3′-azidothymidine-5′-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells
    • Törnevik Y, Ullman B, Balzarini J, Wahren B, Eriksson S: Cytotoxicity of 3′-azido-3′-deoxythymidine correlates with 3′-azidothymidine-5′-monophosphate (AZTMP) levels, whereas anti human immunodeficiency virus (HIV) activity correlates with 3′-azidothymidine-5′-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells. Biochem Pharmacol 1995, 49:829-837.
    • (1995) Biochem Pharmacol , vol.49 , pp. 829-837
    • Törnevik, Y.1    Ullman, B.2    Balzarini, J.3    Wahren, B.4    Eriksson, S.5
  • 24
    • 0029010124 scopus 로고
    • Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection
    • Stretcher BN: Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection. Clin Pharmacokinet 1995, 29:46-65.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 46-65
    • Stretcher, B.N.1
  • 25
    • 0025873389 scopus 로고
    • Pharmacokinetic optimisation of anticancer therapy
    • Liliemark J, Peterson C: Pharmacokinetic optimisation of anticancer therapy. Clin Pharmacokinet 1991, 21:213-231.
    • (1991) Clin Pharmacokinet , vol.21 , pp. 213-231
    • Liliemark, J.1    Peterson, C.2
  • 26
    • 0000243802 scopus 로고
    • Pharmacokinetics of arabinosylcytosine
    • Plunkett W, Gandhi V: Pharmacokinetics of arabinosylcytosine. J Infusion Chemother 1992, 2:167-176.
    • (1992) J Infusion Chemother , vol.2 , pp. 167-176
    • Plunkett, W.1    Gandhi, V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.