메뉴 건너뛰기




Volumn 136, Issue 4, 2005, Pages 991-1001

Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia

Author keywords

Corticosterone; Neuroplasticity; pCREB; Running; Stroke rehabilitation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; ENDOTHELIN 1; SOMATOMEDIN C; SYNAPSIN I;

EID: 29044439363     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.08.037     Document Type: Article
Times cited : (148)

References (72)
  • 1
    • 2442475297 scopus 로고    scopus 로고
    • The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise
    • P.A. Adlard, V.M. Perreau, C. Engesser-Cesar, C.W. Cotman The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise Neurosci Lett 363 2004 43 48
    • (2004) Neurosci Lett , vol.363 , pp. 43-48
    • Adlard, P.A.1    Perreau, V.M.2    Engesser-Cesar, C.3    Cotman, C.W.4
  • 3
    • 0036973397 scopus 로고    scopus 로고
    • Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus
    • M. Alonso, M.R. Vianna, I. Izquierdo, J.H. Medina Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus Cell Mol Neurobiol 22 2002 663 674
    • (2002) Cell Mol Neurobiol , vol.22 , pp. 663-674
    • Alonso, M.1    Vianna, M.R.2    Izquierdo, I.3    Medina, J.H.4
  • 5
    • 0347928852 scopus 로고    scopus 로고
    • Neuroprotection associated with running: Is it a result of increased endogenous neurotrophic factors?
    • E.T. Ang, P.T. Wong, S. Moochhala, Y.K. Ng Neuroprotection associated with running is it a result of increased endogenous neurotrophic factors? Neuroscience 118 2003 335 345
    • (2003) Neuroscience , vol.118 , pp. 335-345
    • Ang, E.T.1    Wong, P.T.2    Moochhala, S.3    Ng, Y.K.4
  • 6
    • 20444398484 scopus 로고    scopus 로고
    • Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    • N.C. Berchtold, G. Chinn, M. Chou, J.P. Kesslak, C.W. Cotman Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus Neuroscience 133 2005 853 861
    • (2005) Neuroscience , vol.133 , pp. 853-861
    • Berchtold, N.C.1    Chinn, G.2    Chou, M.3    Kesslak, J.P.4    Cotman, C.W.5
  • 7
    • 0035879070 scopus 로고    scopus 로고
    • Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury
    • J. Biernaskie, D. Corbett Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury J Neurosci 21 2001 5272 5280
    • (2001) J Neurosci , vol.21 , pp. 5272-5280
    • Biernaskie, J.1    Corbett, D.2
  • 8
    • 0034794176 scopus 로고    scopus 로고
    • A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats
    • J. Biernaskie, D. Corbett, J. Peeling, J. Wells, H. Lei A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats Magn Reson Med 46 2001 827 830
    • (2001) Magn Reson Med , vol.46 , pp. 827-830
    • Biernaskie, J.1    Corbett, D.2    Peeling, J.3    Wells, J.4    Lei, H.5
  • 9
    • 16244363331 scopus 로고    scopus 로고
    • Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats
    • J. Biernaskie, A. Szymanska, V. Windle, D. Corbett Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats Eur J Neurosci 21 2005 989 999
    • (2005) Eur J Neurosci , vol.21 , pp. 989-999
    • Biernaskie, J.1    Szymanska, A.2    Windle, V.3    Corbett, D.4
  • 10
    • 0346725081 scopus 로고    scopus 로고
    • Behaviorally-induced ultrastructural plasticity in the hippocampal region after cerebral ischemia
    • T.L. Briones, E. Suh, L. Jozsa, H. Hattar, J. Chai, M. Wadowska Behaviorally-induced ultrastructural plasticity in the hippocampal region after cerebral ischemia Brain Res 997 2004 137 146
    • (2004) Brain Res , vol.997 , pp. 137-146
    • Briones, T.L.1    Suh, E.2    Jozsa, L.3    Hattar, H.4    Chai, J.5    Wadowska, M.6
  • 12
    • 18144446836 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates effects of exercise on the brain
    • E. Carro, A. Nunez, S. Busiguina, I. Torres-Aleman Circulating insulin-like growth factor I mediates effects of exercise on the brain J Neurosci 20 2000 2926 2933
    • (2000) J Neurosci , vol.20 , pp. 2926-2933
    • Carro, E.1    Nunez, A.2    Busiguina, S.3    Torres-Aleman, I.4
  • 13
    • 0035426212 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy
    • E. Carro, J.L. Trejo, S. Busiguina, I. Torres-Aleman Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy J Neurosci 21 2001 5678 5684
    • (2001) J Neurosci , vol.21 , pp. 5678-5684
    • Carro, E.1    Trejo, J.L.2    Busiguina, S.3    Torres-Aleman, I.4
  • 15
    • 0027228373 scopus 로고
    • Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke
    • M.C. Comelli, D. Guidolin, M.S. Seren, R. Zanoni, R. Canella, R. Rubini, H. Manev Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke Neuroscience 55 1993 473 490
    • (1993) Neuroscience , vol.55 , pp. 473-490
    • Comelli, M.C.1    Guidolin, D.2    Seren, M.S.3    Zanoni, R.4    Canella, R.5    Rubini, R.6    Manev, H.7
  • 17
    • 1342343120 scopus 로고    scopus 로고
    • Exercise pre-conditioning reduces brain damage in ischemic rats that may be associated with regional angiogenesis and cellular overexpression of neurotrophin
    • Y. Ding, J. Li, X. Luan, H. Ding, Q. Lai, J.A. Rafols, J.W. Phillis, J.C. Clark, F.G. Diaz Exercise pre-conditioning reduces brain damage in ischemic rats that may be associated with regional angiogenesis and cellular overexpression of neurotrophin Neuroscience 124 2004 583 591
    • (2004) Neuroscience , vol.124 , pp. 583-591
    • Ding, Y.1    Li, J.2    Luan, X.3    Ding, H.4    Lai, Q.5    Rafols, J.A.6    Phillis, J.W.7    Clark, J.C.8    Diaz, F.G.9
  • 19
    • 0033046355 scopus 로고    scopus 로고
    • Neuroprotective actions of peripherally administered insulin-like growth factor I in the injured olivo-cerebellar pathway
    • A.M. Fernandez, A.G. Gonzalez de la Vega, B. Planas, I. Torres-Aleman Neuroprotective actions of peripherally administered insulin-like growth factor I in the injured olivo-cerebellar pathway Eur J Neurosci 11 1999 2019 2030
    • (1999) Eur J Neurosci , vol.11 , pp. 2019-2030
    • Fernandez, A.M.1    Gonzalez De La Vega, A.G.2    Planas, B.3    Torres-Aleman, I.4
  • 20
    • 0031947836 scopus 로고    scopus 로고
    • BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia
    • I. Ferrer, J. Ballabriga, E. Marti, E. Perez, J. Alberch, E. Arenas BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia Brain Pathol 8 1998 253 261
    • (1998) Brain Pathol , vol.8 , pp. 253-261
    • Ferrer, I.1    Ballabriga, J.2    Marti, E.3    Perez, E.4    Alberch, J.5    Arenas, E.6
  • 21
    • 0035109207 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat
    • I. Ferrer, J. Krupinski, E. Goutan, E. Marti, S. Ambrosio, E. Arenas Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat Acta Neuropathol 101 2001 229 238
    • (2001) Acta Neuropathol , vol.101 , pp. 229-238
    • Ferrer, I.1    Krupinski, J.2    Goutan, E.3    Marti, E.4    Ambrosio, S.5    Arenas, E.6
  • 22
    • 15744391499 scopus 로고    scopus 로고
    • Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor
    • O.L. Gobbo, S.M. O'Mara Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor Behav Brain Res 159 2005 21 26
    • (2005) Behav Brain Res , vol.159 , pp. 21-26
    • Gobbo, O.L.1    O'Mara, S.M.2
  • 23
    • 10744223115 scopus 로고    scopus 로고
    • Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: Water maze performance correlates
    • A. Goldbart, B.W. Row, L. Kheirandish, A. Schurr, E. Gozal, S.Z. Guo, R.S. Payne, Z. Cheng, K.R. Brittian, D. Gozal Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region water maze performance correlates Neuroscience 122 2003 585 590
    • (2003) Neuroscience , vol.122 , pp. 585-590
    • Goldbart, A.1    Row, B.W.2    Kheirandish, L.3    Schurr, A.4    Gozal, E.5    Guo, S.Z.6    Payne, R.S.7    Cheng, Z.8    Brittian, K.R.9    Gozal, D.10
  • 24
    • 0036850342 scopus 로고    scopus 로고
    • Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity
    • F. Gomez-Pinilla, Z. Ying, R.R. Roy, R. Molteni, V.R. Edgerton Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity J Neurophysiol 88 2002 2187 2195
    • (2002) J Neurophysiol , vol.88 , pp. 2187-2195
    • Gomez-Pinilla, F.1    Ying, Z.2    Roy, R.R.3    Molteni, R.4    Edgerton, V.R.5
  • 25
    • 3042818479 scopus 로고    scopus 로고
    • The upregulation of plasticity-related proteins following TBI is disrupted with acute voluntary exercise
    • G.S. Griesbach, F. Gomez-Pinilla, D.A. Hovda The upregulation of plasticity-related proteins following TBI is disrupted with acute voluntary exercise Brain Res 1016 2004 154 162
    • (2004) Brain Res , vol.1016 , pp. 154-162
    • Griesbach, G.S.1    Gomez-Pinilla, F.2    Hovda, D.A.3
  • 26
    • 1642544036 scopus 로고    scopus 로고
    • Voluntary exercise following traumatic brain injury: Brain-derived neurotrophic upregulation and recovery of function
    • G.S. Griesbach, D.A. Hovda, R. Molteni, A. Wu, F. Gomez-Pinilla Voluntary exercise following traumatic brain injury Brain-derived neurotrophic upregulation and recovery of function Neuroscience 125 2004 129 139
    • (2004) Neuroscience , vol.125 , pp. 129-139
    • Griesbach, G.S.1    Hovda, D.A.2    Molteni, R.3    Wu, A.4    Gomez-Pinilla, F.5
  • 29
    • 0030158237 scopus 로고    scopus 로고
    • Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat
    • B.B. Johansson, A.L. Ohlsson Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat Exp Neurol 139 1996 322 327
    • (1996) Exp Neurol , vol.139 , pp. 322-327
    • Johansson, B.B.1    Ohlsson, A.L.2
  • 31
    • 0037008426 scopus 로고    scopus 로고
    • Treadmill exercise increases cell proliferation without altering of apoptosis in dentate gyrus of Sprague-Dawley rats
    • S.H. Kim, H.B. Kim, M.H. Jang, B.V. Lim, Y.J. Kim, Y.P. Kim, S.S. Kim, E.H. Kim, C.J. Kim Treadmill exercise increases cell proliferation without altering of apoptosis in dentate gyrus of Sprague-Dawley rats Life Sci 71 2002 1331 1340
    • (2002) Life Sci , vol.71 , pp. 1331-1340
    • Kim, S.H.1    Kim, H.B.2    Jang, M.H.3    Lim, B.V.4    Kim, Y.J.5    Kim, Y.P.6    Kim, S.S.7    Kim, E.H.8    Kim, C.J.9
  • 33
    • 0029902028 scopus 로고    scopus 로고
    • Synaptogenesis and Fos expression in the motor cortex of the adult rat following motor skill learning
    • J.A. Kleim, E. Lussnig, E.R. Schwartz, T.A. Comery, W.T. Greenough Synaptogenesis and Fos expression in the motor cortex of the adult rat following motor skill learning J Neurosci 16 1996 4529 4535
    • (1996) J Neurosci , vol.16 , pp. 4529-4535
    • Kleim, J.A.1    Lussnig, E.2    Schwartz, E.R.3    Comery, T.A.4    Greenough, W.T.5
  • 34
    • 7244221842 scopus 로고    scopus 로고
    • Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise
    • A.Y. Klintsova, E. Dickson, R. Yoshida, W.T. Greenough Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise Brain Res 1028 2004 92 104
    • (2004) Brain Res , vol.1028 , pp. 92-104
    • Klintsova, A.Y.1    Dickson, E.2    Yoshida, R.3    Greenough, W.T.4
  • 35
    • 0028841482 scopus 로고
    • Regulation of brain-derived neurotrohic factor gene expression after transient middle cerebral artery occlusion with and without brain damage
    • Z. Kokaia, Q. Zhao, M. Kokaia, E. Elmer, M. Metsis, M.-L. Smith, B.K. Siesjo, O. Lindvall Regulation of brain-derived neurotrohic factor gene expression after transient middle cerebral artery occlusion with and without brain damage Exp Neurol 136 1995 73 88
    • (1995) Exp Neurol , vol.136 , pp. 73-88
    • Kokaia, Z.1    Zhao, Q.2    Kokaia, M.3    Elmer, E.4    Metsis, M.5    Smith, M.-L.6    Siesjo, B.K.7    Lindvall, O.8
  • 36
    • 0038579644 scopus 로고    scopus 로고
    • Molecular correlates of impaired prefrontal plasticity in response to chronic stress
    • S.D. Kuipers, A. Trentani, J.A. Den Boer, G.J. Ter Horst Molecular correlates of impaired prefrontal plasticity in response to chronic stress J Neurochem 85 2003 1312 1323
    • (2003) J Neurochem , vol.85 , pp. 1312-1323
    • Kuipers, S.D.1    Trentani, A.2    Den Boer, J.A.3    Ter Horst, G.J.4
  • 38
    • 3042755032 scopus 로고    scopus 로고
    • Insulin-like growth factor I is required for vessel remodeling in the adult brain
    • C. Lopez-Lopez, D. LeRoith, I. Torres-Aleman Insulin-like growth factor I is required for vessel remodeling in the adult brain Proc Natl Acad Sci U S A 101 2004 9833 9838
    • (2004) Proc Natl Acad Sci U S a , vol.101 , pp. 9833-9838
    • Lopez-Lopez, C.1    Leroith, D.2    Torres-Aleman, I.3
  • 39
    • 0036790736 scopus 로고    scopus 로고
    • Cardiovascular stress during a contemporary stroke rehabilitation program: Is the intensity adequate to induce a training effect?
    • M.J. MacKay-Lyons, L. Makrides Cardiovascular stress during a contemporary stroke rehabilitation program is the intensity adequate to induce a training effect? Arch Phys Med Rehabil 83 2002 1378 1383
    • (2002) Arch Phys Med Rehabil , vol.83 , pp. 1378-1383
    • MacKay-Lyons, M.J.1    Makrides, L.2
  • 40
    • 0345447692 scopus 로고    scopus 로고
    • The effect of voluntary exercise exposure on histological and neurobehavioral outcomes after ischemic brain injury in the rat
    • R. Marin, A. Williams, S. Hale, B. Burge, M. Mense, R. Bauman, F. Tortella The effect of voluntary exercise exposure on histological and neurobehavioral outcomes after ischemic brain injury in the rat Physiol Behav 80 2003 167 175
    • (2003) Physiol Behav , vol.80 , pp. 167-175
    • Marin, R.1    Williams, A.2    Hale, S.3    Burge, B.4    Mense, M.5    Bauman, R.6    Tortella, F.7
  • 41
    • 0033541636 scopus 로고    scopus 로고
    • Transient increase of synapsin-I immunoreactivity in the mossy fiber layer of the hippocampus after transient forebrain ischemia in the Mongolian gerbil
    • E. Marti, I. Ferrer, J. Blasi Transient increase of synapsin-I immunoreactivity in the mossy fiber layer of the hippocampus after transient forebrain ischemia in the Mongolian gerbil Brain Res 824 1999 153 160
    • (1999) Brain Res , vol.824 , pp. 153-160
    • Marti, E.1    Ferrer, I.2    Blasi, J.3
  • 42
    • 0037130346 scopus 로고    scopus 로고
    • CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning
    • M. Mizuno, K. Yamada, N. Maekawa, K. Saito, M. Seishima, T. Nabeshima CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning Behav Brain Res 133 2002 135 141
    • (2002) Behav Brain Res , vol.133 , pp. 135-141
    • Mizuno, M.1    Yamada, K.2    Maekawa, N.3    Saito, K.4    Seishima, M.5    Nabeshima, T.6
  • 43
    • 0034666119 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats
    • M. Mizuno, K. Yamada, A. Olariu, H. Nawa, T. Nabeshima Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats J Neurosci 20 2000 7116 7121
    • (2000) J Neurosci , vol.20 , pp. 7116-7121
    • Mizuno, M.1    Yamada, K.2    Olariu, A.3    Nawa, H.4    Nabeshima, T.5
  • 44
    • 1442316352 scopus 로고    scopus 로고
    • Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray
    • R. Molteni, Z. Ying, F. Gomez-Pinilla Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray Eur J Neurosci 16 2002 1107 1116
    • (2002) Eur J Neurosci , vol.16 , pp. 1107-1116
    • Molteni, R.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 45
    • 0037008866 scopus 로고    scopus 로고
    • Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats
    • A. Nagakura, N. Takagi, S. Takeo Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats Neuroscience 113 2002 519 528
    • (2002) Neuroscience , vol.113 , pp. 519-528
    • Nagakura, A.1    Takagi, N.2    Takeo, S.3
  • 46
    • 0010330438 scopus 로고    scopus 로고
    • Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
    • S.A. Neeper, F. Gomez-Pinilla, J. Choi, C.W. Cotman Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain Brain Res 726 1996 49 56
    • (1996) Brain Res , vol.726 , pp. 49-56
    • Neeper, S.A.1    Gomez-Pinilla, F.2    Choi, J.3    Cotman, C.W.4
  • 49
    • 0033496646 scopus 로고    scopus 로고
    • Early training may exacerbate brain damage after focal brain ischemia in the rat
    • A. Risedal, J. Zeng, B.B. Johansson Early training may exacerbate brain damage after focal brain ischemia in the rat J Cereb Blood Flow Metab 19 1999 997 1003
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 997-1003
    • Risedal, A.1    Zeng, J.2    Johansson, B.B.3
  • 50
    • 0032583213 scopus 로고    scopus 로고
    • Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone
    • M.J.M. Schaaf, J. de Jong, R. de Kloet, E. Vreugdenhil Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone Brain Res 813 1998 112 120
    • (1998) Brain Res , vol.813 , pp. 112-120
    • Schaaf, M.J.M.1    De Jong, J.2    De Kloet, R.3    Vreugdenhil, E.4
  • 51
  • 52
    • 1842575785 scopus 로고    scopus 로고
    • Effect of brain-derived neurotrophic factor treatment and forced arm use on functional motor recovery after small cortical ischemia
    • W.R. Schabitz, C. Berger, R. Kollmar, M. Seitz, E. Tanay, M. Kiessling, S. Schwab, C. Sommer Effect of brain-derived neurotrophic factor treatment and forced arm use on functional motor recovery after small cortical ischemia Stroke 35 2004 992 997
    • (2004) Stroke , vol.35 , pp. 992-997
    • Schabitz, W.R.1    Berger, C.2    Kollmar, R.3    Seitz, M.4    Tanay, E.5    Kiessling, M.6    Schwab, S.7    Sommer, C.8
  • 53
    • 0030951213 scopus 로고    scopus 로고
    • Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats
    • W.R. Schabitz, S. Schwab, M. Spranger, W. Hacke Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats J Cereb Blood Flow Metab 17 1997 500 506
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 500-506
    • Schabitz, W.R.1    Schwab, S.2    Spranger, M.3    Hacke, W.4
  • 54
    • 0034536215 scopus 로고    scopus 로고
    • The neurotrophin hypothesis for synaptic plasticity
    • A.F. Schinder, M. Poo The neurotrophin hypothesis for synaptic plasticity Trends Neurosci 23 2000 639 645
    • (2000) Trends Neurosci , vol.23 , pp. 639-645
    • Schinder, A.F.1    Poo, M.2
  • 55
    • 0038391161 scopus 로고    scopus 로고
    • Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor
    • K.N. Shaw, S. Commins, S.M. O'Mara Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor Eur J Neurosci 17 2003 2438 2446
    • (2003) Eur J Neurosci , vol.17 , pp. 2438-2446
    • Shaw, K.N.1    Commins, S.2    O'Mara, S.M.3
  • 56
    • 0035900626 scopus 로고    scopus 로고
    • Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus
    • H. Shen, L. Tong, R. Balazs, C.W. Cotman Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus Neuroscience 107 2001 219 229
    • (2001) Neuroscience , vol.107 , pp. 219-229
    • Shen, H.1    Tong, L.2    Balazs, R.3    Cotman, C.W.4
  • 57
    • 0028970281 scopus 로고
    • Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
    • M.A. Smith, S. Makino, R. Kvetnansky, R.M. Post Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus J Neurosci 15 1995 1768 1777
    • (1995) J Neurosci , vol.15 , pp. 1768-1777
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 58
    • 0028086162 scopus 로고
    • Reduced mortality and brain damage after locomotor activity in gerbil forebrain ischemia
    • W. Stummer, D.V.M. Weber, B. Tranmer, A. Baethmann, O. Kempski Reduced mortality and brain damage after locomotor activity in gerbil forebrain ischemia Stroke 25 1994 1862 1869
    • (1994) Stroke , vol.25 , pp. 1862-1869
    • Stummer, W.1    Weber, D.V.M.2    Tranmer, B.3    Baethmann, A.4    Kempski, O.5
  • 59
    • 0030924231 scopus 로고    scopus 로고
    • Insulin-like growth factor-I attenuates apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats
    • M. Tagami, K. Ikeda, Y. Nara, H. Fujino, A. Kubota, F. Numano, Y. Yamori Insulin-like growth factor-I attenuates apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats Lab Invest 76 1997 613 617
    • (1997) Lab Invest , vol.76 , pp. 613-617
    • Tagami, M.1    Ikeda, K.2    Nara, Y.3    Fujino, H.4    Kubota, A.5    Numano, F.6    Yamori, Y.7
  • 60
    • 0034445988 scopus 로고    scopus 로고
    • Serum growth factors and neuroprotective surveillance: Focus on IGF-I
    • I. Torres-Aleman Serum growth factors and neuroprotective surveillance focus on IGF-I Mol Neurobiol 21 2000 153 160
    • (2000) Mol Neurobiol , vol.21 , pp. 153-160
    • Torres-Aleman, I.1
  • 61
    • 0035283153 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus
    • J.L. Trejo, E. Carro, I. Torres-Aleman Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus J Neurosci 21 2001 1628 1634
    • (2001) J Neurosci , vol.21 , pp. 1628-1634
    • Trejo, J.L.1    Carro, E.2    Torres-Aleman, I.3
  • 63
    • 0242653760 scopus 로고    scopus 로고
    • Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic plasticity
    • S. Vaynman, Z. Ying, F. Gomez-Pinilla Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic plasticity Neuroscience 122 2003 647 657
    • (2003) Neuroscience , vol.122 , pp. 647-657
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 64
    • 2342544136 scopus 로고    scopus 로고
    • Exercise induces BDNF and synapsin-I to specific hippocampal subfields
    • S. Vaynman, Z. Ying, F. Gomez-Pinilla Exercise induces BDNF and synapsin-I to specific hippocampal subfields J Neurosci Res 76 2004 356 362
    • (2004) J Neurosci Res , vol.76 , pp. 356-362
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 65
    • 9644270414 scopus 로고    scopus 로고
    • Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
    • S. Vaynman, Z. Ying, F. Gomez-Pinilla Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition Eur J Neurosci 20 2004 2580 2590
    • (2004) Eur J Neurosci , vol.20 , pp. 2580-2590
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 66
    • 0032530675 scopus 로고    scopus 로고
    • Neurotrophins induce formation of functional excitatory and inhibitory synapses between cultured hippocampal neurons
    • C. Vicario-Abejon, C. Collin, R.D. McKay, M. Segal Neurotrophins induce formation of functional excitatory and inhibitory synapses between cultured hippocampal neurons J Neurosci 18 1998 7256 7271
    • (1998) J Neurosci , vol.18 , pp. 7256-7271
    • Vicario-Abejon, C.1    Collin, C.2    McKay, R.D.3    Segal, M.4
  • 67
    • 0031799182 scopus 로고    scopus 로고
    • A new approach to retrain gait in stroke patients through body weight support and treadmill stimulation
    • M. Visintin, H. Barbeau, N. Korner-Bitensky, N.E. Mayo A new approach to retrain gait in stroke patients through body weight support and treadmill stimulation Stroke 29 1998 1122 1128
    • (1998) Stroke , vol.29 , pp. 1122-1128
    • Visintin, M.1    Barbeau, H.2    Korner-Bitensky, N.3    Mayo, N.E.4
  • 68
    • 0030608446 scopus 로고    scopus 로고
    • The role of the cyclic AMP-responsive element binding protein (CREB) in hypoxic-ischemic brain damage and repair
    • M. Walton, E. Sirimanne, C. Williams, P. Gluckman, M. Dragunow The role of the cyclic AMP-responsive element binding protein (CREB) in hypoxic-ischemic brain damage and repair Brain Res Mol Brain Res 43 1996 21 29
    • (1996) Brain Res Mol Brain Res , vol.43 , pp. 21-29
    • Walton, M.1    Sirimanne, E.2    Williams, C.3    Gluckman, P.4    Dragunow, M.5
  • 69
    • 0031415298 scopus 로고    scopus 로고
    • Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat
    • K. Yamashita, C. Weissner, D. Lindholm, H. Thoenen, K.-A. Hossman Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat Metab Brain Dis 12 1997 271 280
    • (1997) Metab Brain Dis , vol.12 , pp. 271-280
    • Yamashita, K.1    Weissner, C.2    Lindholm, D.3    Thoenen, H.4    Hossman, K.-A.5
  • 70
    • 0037457353 scopus 로고    scopus 로고
    • Early and late treadmill training after focal brain ischemia in rats
    • Y.R. Yang, R.Y. Wang, P.S. Wang Early and late treadmill training after focal brain ischemia in rats Neurosci Lett 339 2003 91 94
    • (2003) Neurosci Lett , vol.339 , pp. 91-94
    • Yang, Y.R.1    Wang, R.Y.2    Wang, P.S.3
  • 71
    • 0034988984 scopus 로고    scopus 로고
    • Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system
    • Y. Zhang, W.M. Pardridge Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system Stroke 32 2001 1378 1384
    • (2001) Stroke , vol.32 , pp. 1378-1384
    • Zhang, Y.1    Pardridge, W.M.2
  • 72
    • 0035877195 scopus 로고    scopus 로고
    • Enriched environment influences brain-derived neurotrophic factor levels in rat forebrain after focal stroke
    • L.R. Zhao, A. Risedal, A. Wojcik, J. Hejzlar, B.B. Johansson, Z. Kokaia Enriched environment influences brain-derived neurotrophic factor levels in rat forebrain after focal stroke Neurosci Lett 305 2001 169 172
    • (2001) Neurosci Lett , vol.305 , pp. 169-172
    • Zhao, L.R.1    Risedal, A.2    Wojcik, A.3    Hejzlar, J.4    Johansson, B.B.5    Kokaia, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.