Effect of Brain-Derived Neurotrophic Factor Treatment and Forced Arm Use on Functional Motor Recovery after Small Cortical Ischemia

Stroke

Volumn 35, Issue 4, 2004, Pages 992-997

  Schäbitz, Wolfe Rüdiger ^a   Berger, C ^a   Kollmar, R ^a   Seitz, M ^a   Tanay, E ^a   Kiessling, M ^a   Schwab, S ^a   Sommer, C ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Brain derived neurotrophic factor; Cerebral ischemia; Forced arm use; Photothrombosis; Regeneration

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 5; SYNAPTOPHYSIN;

ANIMAL MODEL; ANIMAL TISSUE; ARM; ARTICLE; ASTROCYTOSIS; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MOTOR PERFORMANCE; NONHUMAN; PHYSIOTHERAPY; PLASTER CAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STROKE; THROMBOSIS;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL INFARCTION; COMBINED MODALITY THERAPY; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMOBILIZATION; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; NERVE REGENERATION; PHYSICAL THERAPY MODALITIES; RATS; RATS, WISTAR; SYNAPTOPHYSIN; UPPER EXTREMITY;

EID: 1842575785     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000119754.85848.0D     Document Type: Article

References (37)

1. Schäbitz WR, Schwab S, Spranger M, Hacke W. BDNF reduces infarct size after permanent MCA occlusion in the rat. J Cereb Blood Flow Metab. 1997;17:500-506.
2. Schäbitz WR, Sommer C, Zoder W, Kiessling M, Schwaninger M, Schwab S. Intravenous BDNF reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia. Stroke. 2000;31:2212-2217.
3. Wu D, Pardridge WM. Neuroprotection with noninvasive neurotrophin delivery to the brain. Proc Natl Acad Sci USA. 1999;96:254-259.
4. Kiprianova I, Sandkühler J, Schwab S, Hoyer S, Spranger M. BDNF improves long term potentiation and cognitive functions after transient forebrain ischemia in the rat. Exp Neurol. 1999;159:511-519.
5. Nudo RJ, Plautz EJ, Frost SB. Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve. 2001;24: 1000-1019.
6. Taub E, Crago JE, Burgio LD, Groomes TE, Cook EW, DeLuca SC, Miller NE. An operant approach to rehabilitation medicine: overcoming learned non-use by shaping. J Exp Anal Behav. 1994;61:281-293.
7. Miltner WHR, Bauder H, Sommer M, Dettmers C, Taub E. Effects of constraint-induced movement therapy on patients with chronic motor deficits after stroke: a replication. Stroke. 1999;30:586-592.
8. Wolf SL, Lecraw DE, Barton LA, Jann BB. Forced use of hemiplegic upper extremities to reverse the effect of learned nonuse among Chonic stroke and head-injured patients. Exp Neurol. 1994;104:125-132
9. Kozlowski DA, James DC, Schallert T. Use-dependent exaggeration of neuronal injury following unilateral sensorimotor cortex lesions. J Neurosci. 1996;16:4776-4786.
10. Humm JL, Kozlowski DA, James DC, Gotts JE, Schallert T. Use-dependent exacerbation of brain damage occurs during an early post-lesion vulnerable period. Brain Res. 1998;783:286-292.
11. Risedal A, Zeng J, Johansson BB. Early training may exacerbate brain damage after focal brain ischemia in the rat. J Cereb Blood Flow Metab. 1999;19:997-1003.
12. Bland TS, Schallert T, Strong R, Aronowski J, Grotta JC. Early exclusive use of the affected forelimb-after moderate transient focal ischemia in rats: functional and anatomic outcome. Stroke. 2000;31:1144-1152.
13. Bland ST, Pillai RN, Aronowski J, Grotta JC, Schallert T. Early overuse and disuse of the affected forelimb after moderately severe intraluminal suture occlusion of the middle cerebral artery in rats. Behav Brain Res. 2001;126:33.
14. Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol. 1985;17:497-504.
15. Schallert T, Hernandez TD, Barth TM. Recovery of function after brain damage: severe and chronic disruption by diazepam. Brain Res. 1986; 379:104-111.
16. Hamm RJ, Pike BR, O'Dell DM, Lyeth BG, Jenkins LW. The Rotarod test: an evaluation of its effectiveness in motor deficits following traumatic brain injury. J Neurotrauma. 1994;11:187-196.
17. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M: therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke. 2001;32:1005-1011.
18. Schallert T, Kozlowski DA, Humm JL, Cocke RR. Use-dependent structural events in recovery of function. Adv Neurol. 1997;73:229-238.
19. Hargreaves H, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 1988;32:77-88.
20. Germano AF, Dixon CE, d'Avella D, Hayes RL, Tomasello F. Behavioral deficits following experimental subarachnoid hemorrhage: in the rat. J Neurotrauma. 1994;11:345-353.
21. Sommer C, Kiessling M. Ischemia and ischemia tolerance induction differentially regulate protein expression of GluR1, GluR2, and AMPA receptor binding protein (ABP) in the gerbil hippocampus: GluR2 (GluR-B) reduction does not predict neuronal death. Stroke. 2002;33: 1093-1100.
22. Kawamata T, Dietrich WD, Schallert T, Gotts JE, Cocke RR, Benowitz LI, Finklestein SP. Intracisternal bFGF enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc Natl Acad Sci. U S A. 1997;94: 8179-84.
23. Kawamata T, Ren J, Chan TC, Charette M, Finklestein SP. Intracisternal OP-1 enhances functional recovery following focal stroke. Neuroreport. 1998;9:1441-1445.
24. Ren J, Kaplan PL, Charette MF, Speller H, Finklestein SP. Time window of intracisternal OP-1 in enhancing functional recovery after stroke. Neuropharmacology. 2000;39:860-865.
25. A-receptor expression in the surround of cerebral photothrombosis. J Cereb Blood Flow Metab. 1996;16:906-914.
26. A receptors in the cortical penumbra. Mol Brain Res. 2003;111:24-30.
27. Stroemer RP, Kent TA, Hulsebosch CE. Neocortical neural sprouting, synaptogenesis, and behavioral recovery following neocortical infarction in rats. Stroke. 1995;26:2135-2144.
28. Hess G, Donoghue JP. Long-term potentiation of horizontal connections provides a mechanism to reorganize cortical maps. J Neurophysiol. 1994; 71:2543-2547.
29. Stroemer RP, Kent TA, Hulsebosch CE. Enhanced neocortical neural sprouting, synaptogenesis, and behavioral recovery with D-amphetamine therapy after neocortical infarction in rats. Stroke. 1998;29:2381-2393.
30. Horch HW, Katz LC. BDNF release from single cells elicits local dendritic growth in nearby neurons. Nat Neurosci. 2002;5:1177-1184.
31. Tucker RP. The role of microtubule-associated proteins in brain morphogenesis: a review. Brain Res Rev. 1990;15:101-120.
32. Acarin L, Gonzalez B, Castellano B. Triflusal posttreatment inhibits glial NF-κb, downregulates the glial response, and is neuroprotective in an excitotoxic injury model in postnatal brain. Stroke. 2001;32:2394-2402.
33. Hart CL, Davis GW, Barth TM. Forced activity facilitates recovery of function following cortical lesions in rats. Natl Neurotr Soc Abstr. 1997;101. Abstract.
34. Farrell R, Evans S, Corbett D. Environmental enrichment enhances recovery of function but exacerbates ischemic cell death. Neuroscience. 2001;107:585-592.
35. Tillerson JL, Cohen AD, Philhower J, Miller GW, Zigmond MJ, Schallert T. Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine. J Neurosci. 2001;21:4427-4435.
36. Bland ST, Gonzales RA, Schallert T. Movement-related glutamate levels in rat hippocampus, striatum, and sensorimotor cortex. Neurosci Lett. 1999;277:119-122.
37. Neeper SA, Gomez-Pinilla F, Choi J, Cotman CW. Physical activity increases mRNA for BDNF and NGF in rat brain. Brain Res. 1996;726:49-56.