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Volumn 51, Issue 6, 2005, Pages 658-666

CYP2A13, CYP2A6, and the risk of lung adenocarcinoma in a Japanese population

Author keywords

CYP2A13; CYP2A6; Lung adenocarcinoma; Tobacco specific N nitrosamine

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2A13; CYTOCHROME P450 2A6; DNA; UNCLASSIFIED DRUG;

EID: 28544447343     PISSN: 13449702     EISSN: 13475207     Source Type: Journal    
DOI: 10.1248/jhs.51.658     Document Type: Article
Times cited : (13)

References (47)
  • 2
    • 0025012598 scopus 로고
    • Genetic predisposition to lung cancer
    • Law, M. R. (1990) Genetic predisposition to lung cancer. Br. J. Cancer, 61, 195-206.
    • (1990) Br. J. Cancer , vol.61 , pp. 195-206
    • Law, M.R.1
  • 3
    • 0027304210 scopus 로고
    • Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population
    • Nakachi, K., Imai, K., Hayashi, S. and Kawajiri, K. (1993) Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res., 53, 2994-2999.
    • (1993) Cancer Res. , vol.53 , pp. 2994-2999
    • Nakachi, K.1    Imai, K.2    Hayashi, S.3    Kawajiri, K.4
  • 4
    • 33845630951 scopus 로고    scopus 로고
    • Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer
    • Kiyohara, C. (2000) Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer. J. Epidemiol., 10, 349-360.
    • (2000) J. Epidemiol. , vol.10 , pp. 349-360
    • Kiyohara, C.1
  • 5
    • 0026741674 scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells
    • Smith, T. J., Guo, Z., Gonzalez, F. J., Guengerich, F. P., Stoner, G. D. and Yang, C. S. (1992) Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells. Cancer Res., 52, 1757-1763.
    • (1992) Cancer Res. , vol.52 , pp. 1757-1763
    • Smith, T.J.1    Guo, Z.2    Gonzalez, F.J.3    Guengerich, F.P.4    Stoner, G.D.5    Yang, C.S.6
  • 6
    • 0031037572 scopus 로고    scopus 로고
    • Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanol, and N′-nitrosonornicotine in human hepatic microsomes
    • Staretz, M. E., Murphy, S. E., Patten, C. J., Nunes, M. G., Koehl, W., Amin, S., Koenig, L. A., Guengerich, F. P. and Hecht, S. S. (1997) Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanol, and N′-nitrosonornicotine in human hepatic microsomes. Drug Metab. Dispos., 25, 154-162.
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 154-162
    • Staretz, M.E.1    Murphy, S.E.2    Patten, C.J.3    Nunes, M.G.4    Koehl, W.5    Amin, S.6    Koenig, L.A.7    Guengerich, F.P.8    Hecht, S.S.9
  • 7
    • 0141688389 scopus 로고    scopus 로고
    • Genetic influences on smoking behavior and nicotine dependence: A review
    • Yoshimasu, K. and Kiyohara, C. (2003) Genetic influences on smoking behavior and nicotine dependence: a review. J. Epidemiol., 13, 183-192.
    • (2003) J. Epidemiol. , vol.13 , pp. 183-192
    • Yoshimasu, K.1    Kiyohara, C.2
  • 9
    • 0030697098 scopus 로고    scopus 로고
    • A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin
    • Hadidi, H., Zahlsen, K., Idle, J. R. and Cholerton, S. (1997) A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin. Food Chem. Toxicol., 35, 903-907.
    • (1997) Food Chem. Toxicol. , vol.35 , pp. 903-907
    • Hadidi, H.1    Zahlsen, K.2    Idle, J.R.3    Cholerton, S.4
  • 10
    • 0343433298 scopus 로고    scopus 로고
    • Expression and function of CYP2A genes in humans
    • Rautio, A., Gullsten, H. and Pelkonen, O. (1998) Expression and function of CYP2A genes in humans. Exp. Toxicol. Pathol., 50, 133-134.
    • (1998) Exp. Toxicol. Pathol. , vol.50 , pp. 133-134
    • Rautio, A.1    Gullsten, H.2    Pelkonen, O.3
  • 12
    • 0033550994 scopus 로고    scopus 로고
    • Genetic variation of CYP2A6, smoking, and risk of cancer
    • London, S. J., Idle, J. R., Daly, A. K. and Coetzee, G. A. (1999) Genetic variation of CYP2A6, smoking, and risk of cancer. Lancet, 353, 898-899.
    • (1999) Lancet , vol.353 , pp. 898-899
    • London, S.J.1    Idle, J.R.2    Daly, A.K.3    Coetzee, G.A.4
  • 13
  • 17
    • 0035916969 scopus 로고    scopus 로고
    • Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population
    • Tan, W., Chen, G. F., Xing, D. Y., Song, C. Y., Kadlubar, F. F. and Lin, D. X. (2001) Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. Int. J. Cancer, 95, 96-101.
    • (2001) Int. J. Cancer , vol.95 , pp. 96-101
    • Tan, W.1    Chen, G.F.2    Xing, D.Y.3    Song, C.Y.4    Kadlubar, F.F.5    Lin, D.X.6
  • 18
    • 0034665139 scopus 로고    scopus 로고
    • Human cytochrome P450 CYP2A13: Predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Su, T., Bao, Z., Zhang, Q. Y., Smith, T. J., Hong, J. Y. and Ding, X. (2000) Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res., 60, 5074-5079.
    • (2000) Cancer Res. , vol.60 , pp. 5074-5079
    • Su, T.1    Bao, Z.2    Zhang, Q.Y.3    Smith, T.J.4    Hong, J.Y.5    Ding, X.6
  • 19
    • 0036070530 scopus 로고    scopus 로고
    • Genetic polymorphisms of the human CYP2A13 gene: Identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant
    • Zhang, X., Su, T., Zhang, Q. Y., Gu, J., Caggana, M., Li, H. and Ding, X. (2002) Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant. J. Pharmacol. Exp. Ther., 302, 416-423.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 416-423
    • Zhang, X.1    Su, T.2    Zhang, Q.Y.3    Gu, J.4    Caggana, M.5    Li, H.6    Ding, X.7
  • 20
    • 0041856513 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of the human cyp2a13 gene: Evidence for a null allele
    • Zhang, X., Chen, Y., Liu, Y., Ren, X., Zhang, Q. Y., Caggana, M. and Ding, X. (2003) Single nucleotide polymorphisms of the human cyp2a13 gene: evidence for a null allele. Drug Metab Dispos., 31, 1081-1085.
    • (2003) Drug Metab Dispos. , vol.31 , pp. 1081-1085
    • Zhang, X.1    Chen, Y.2    Liu, Y.3    Ren, X.4    Zhang, Q.Y.5    Caggana, M.6    Ding, X.7
  • 22
    • 0345707570 scopus 로고    scopus 로고
    • Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK
    • Wang, H., Tan, W., Hao, B., Miao, X., Zhou, G., He, F. and Lin, D. (2003) Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res., 63, 8057-8061.
    • (2003) Cancer Res. , vol.63 , pp. 8057-8061
    • Wang, H.1    Tan, W.2    Hao, B.3    Miao, X.4    Zhou, G.5    He, F.6    Lin, D.7
  • 25
    • 0036667958 scopus 로고    scopus 로고
    • Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese
    • Ariyoshi, N., Sekine, H., Saito, K. and Kamataki, T. (2002) Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese. Pharmacogenetics, 12, 501-504.
    • (2002) Pharmacogenetics , vol.12 , pp. 501-504
    • Ariyoshi, N.1    Sekine, H.2    Saito, K.3    Kamataki, T.4
  • 26
    • 0032838745 scopus 로고    scopus 로고
    • Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype
    • Tokyo
    • Nunoya, K., Yokoi, T., Takahashi, Y., Kimura, K., Kinoshita, M. and Kamataki, T. (1999) Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype. J. Biochem. (Tokyo), 126, 402-407.
    • (1999) J. Biochem. , vol.126 , pp. 402-407
    • Nunoya, K.1    Yokoi, T.2    Takahashi, Y.3    Kimura, K.4    Kinoshita, M.5    Kamataki, T.6
  • 27
    • 0032945691 scopus 로고    scopus 로고
    • A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dim-ethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans
    • Nunoya, K., Yokoi, T., Kimura, K., Kainuma, T., Satoh, K., Kinoshita, M. and Kamataki, T. (1999) A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dim-ethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans. J. Pharmacol Exp. Ther., 289, 437-442.
    • (1999) J. Pharmacol Exp. Ther. , vol.289 , pp. 437-442
    • Nunoya, K.1    Yokoi, T.2    Kimura, K.3    Kainuma, T.4    Satoh, K.5    Kinoshita, M.6    Kamataki, T.7
  • 28
    • 0031050648 scopus 로고    scopus 로고
    • Lung carcinoma trends by histologic type in Vaud and Neuchatel, Switzerland, 1974-1994
    • Levi, F., Franceschi, S., La Vecchia, C., Randimbison, L. and Te, V. C. (1997) Lung carcinoma trends by histologic type in Vaud and Neuchatel, Switzerland, 1974-1994. Cancer, 79, 906-914.
    • (1997) Cancer , vol.79 , pp. 906-914
    • Levi, F.1    Franceschi, S.2    La Vecchia, C.3    Randimbison, L.4    Te, V.C.5
  • 29
    • 0029620449 scopus 로고
    • The changing epidemiology of smoking and lung cancer histology
    • Wynder, E. L. and Muscat, J. E. (1995) The changing epidemiology of smoking and lung cancer histology. Environ. Health Perspect., 103, 143-148.
    • (1995) Environ. Health Perspect. , vol.103 , pp. 143-148
    • Wynder, E.L.1    Muscat, J.E.2
  • 31
    • 0029950535 scopus 로고    scopus 로고
    • United States lung carcinoma incidence trends: Declining for most histologic types among males, increasing among females
    • Travis, W. D., Lubin, J., Ries, L. and Devesa, S. (1996) United States lung carcinoma incidence trends: declining for most histologic types among males, increasing among females. Cancer, 77, 2464-2470.
    • (1996) Cancer , vol.77 , pp. 2464-2470
    • Travis, W.D.1    Lubin, J.2    Ries, L.3    Devesa, S.4
  • 32
    • 0030892766 scopus 로고    scopus 로고
    • The increasing incidence of lung adenocarcinoma: Reality or artefact? A review of the epidemiology of lung adenocarcinoma
    • Charloux, A., Quoix, E., Wolkove, N., Small, D., Pauli, G. and Kreisman, H. (1997) The increasing incidence of lung adenocarcinoma: reality or artefact? A review of the epidemiology of lung adenocarcinoma. Int. J. Epidemiol., 26, 14-23.
    • (1997) Int. J. Epidemiol. , vol.26 , pp. 14-23
    • Charloux, A.1    Quoix, E.2    Wolkove, N.3    Small, D.4    Pauli, G.5    Kreisman, H.6
  • 33
    • 0033045320 scopus 로고    scopus 로고
    • Trends of lung cancer incidence by histologic type: A population-based study in Osaka, Japan
    • Sobue, T., Ajiki, W., Tsukuma, H., Oshima, A., Hanai, A. and Fujimoto, I. (1999) Trends of lung cancer incidence by histologic type: a population-based study in Osaka, Japan. Jpn. J. Cancer Res., 90, 6-15.
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 6-15
    • Sobue, T.1    Ajiki, W.2    Tsukuma, H.3    Oshima, A.4    Hanai, A.5    Fujimoto, I.6
  • 35
    • 0024350057 scopus 로고
    • Rapid single-dose model for lung tumor induction in A/J mice by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the effect of diet
    • Hecht, S. S., Morse, M. A., Amin, S., Stoner, G. D., Jordan, K. G., Choi, C. I. and Chung, F. L. (1989) Rapid single-dose model for lung tumor induction in A/J mice by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the effect of diet. Carcinogenesis, 10, 1901-1904.
    • (1989) Carcinogenesis , vol.10 , pp. 1901-1904
    • Hecht, S.S.1    Morse, M.A.2    Amin, S.3    Stoner, G.D.4    Jordan, K.G.5    Choi, C.I.6    Chung, F.L.7
  • 36
    • 0027488025 scopus 로고
    • Cigarette smoking and adenocarcinoma of the lung: The relevance of nicotine-derived N-nitrosamines
    • Hoffmann, D., Rivenson, A., Murphy, S. E., Chung, F.-L., Amin, S. and Hecht, S. S. (1993) Cigarette smoking and adenocarcinoma of the lung: the relevance of nicotine-derived N-nitrosamines. J. Smoking Rel. Disord., 4, 165-190.
    • (1993) J. Smoking Rel. Disord. , vol.4 , pp. 165-190
    • Hoffmann, D.1    Rivenson, A.2    Murphy, S.E.3    Chung, F.-L.4    Amin, S.5    Hecht, S.S.6
  • 37
    • 0028177696 scopus 로고
    • Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: Chemistry, biochemistry, carcinogenicity, and relevance to humans
    • Hoffmann, D., Brunnemann, K. D., Prokopczyk, B. and Djordjevic, M. V. (1994) Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans. J. Toxicol. Environ. Health, 41, 1-52.
    • (1994) J. Toxicol. Environ. Health , vol.41 , pp. 1-52
    • Hoffmann, D.1    Brunnemann, K.D.2    Prokopczyk, B.3    Djordjevic, M.V.4
  • 38
    • 28544441700 scopus 로고    scopus 로고
    • Tobacco Smoke and Involuntary Smoking
    • IARC Monographs of the Evaluation of the Carcinogenic Risk of Chemicals to Humans IARC, Lyon
    • IARC Monographs of the Evaluation of the Carcinogenic Risk of Chemicals to Humans (2002) Tobacco Smoke and Involuntary Smoking, IARC Scientifc Publication no. 83, IARC, Lyon.
    • (2002) IARC Scientifc Publication No. 83
  • 39
    • 0019198928 scopus 로고
    • Risks the passive smoker runs
    • Stock, S. L. (1980) Risks the passive smoker runs. Lancet, 2, 1082.
    • (1980) Lancet , vol.2 , pp. 1082
    • Stock, S.L.1
  • 44
    • 0029336674 scopus 로고
    • Genetic-environmental interactions and low-level exposure to carcinogens
    • Vineis, P. and Martone, T. (1995) Genetic-environmental interactions and low-level exposure to carcinogens. Epidemiology, 6, 455-457.
    • (1995) Epidemiology , vol.6 , pp. 455-457
    • Vineis, P.1    Martone, T.2
  • 45
    • 0036912127 scopus 로고    scopus 로고
    • Why have we failed to find the low penetrance genetic constituents of common cancers?
    • Caporaso, N. E. (2002) Why have we failed to find the low penetrance genetic constituents of common cancers? Cancer Epidemiol. Biomarkers Prev., 11, 1544-1549.
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 1544-1549
    • Caporaso, N.E.1
  • 46
    • 0036201835 scopus 로고    scopus 로고
    • Gene-environment interaction and aetiology of cancer: What does it mean and how can we measure it?
    • Brennan, P. (2002) Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it? Carcinogenesis, 23, 381-387.
    • (2002) Carcinogenesis , vol.23 , pp. 381-387
    • Brennan, P.1
  • 47
    • 0036907407 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes and associations with cancer risk
    • Goode, E. L., Ulrich, C. M. and Potter, J. D. (2002) Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomarkers Prev., 11, 1513-1530.
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 1513-1530
    • Goode, E.L.1    Ulrich, C.M.2    Potter, J.D.3


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