Gene-environment interaction and aetiology of cancer: What does it mean and how can we measure it?

Carcinogenesis

Volumn 23, Issue 3, 2002, Pages 381-387

  Brennan, Paul ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TOXIC SUBSTANCE;

ARTICLE; CANCER; CANCER GENETICS; CANCER LOCALIZATION; CANCER RISK; CONTROLLED STUDY; DNA REPAIR; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EPIDEMIOLOGY; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HIGH RISK POPULATION; HUMAN; LABORATORY; MEDICAL RESEARCH; PRIORITY JOURNAL;

EID: 0036201835     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.3.381     Document Type: Article

References (38)

1. Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers
2. The glutathione S-transferases: Influence of polymorphism on cancer susceptibility
3. Polymorphic NATs and cancer predisposition
4. Markers of DNA repair and susceptibility to cancer in humans: An epidemiologic review
5. Inherited susceptibility to bleomycin-induced chromatid breaks in cultured peripheral blood lymphocytes
6. Functional significance of xpd polymorphic variants: Attenuated apoptosis in human lymphoblastoid cells with the xpd 312 asp/as genotype
7. Nicotine metabolism defect reduces smoking
8. D2 dopamine receptor gene polymorphisms among African-Americans and Mexican-Americans: A lung cancer case-control study
9. Well-done, grilled red meat increases the risk of colorectal adenomas
10. Functional relevance of human ADH polymorphism
11. Sick individuals and sick populations
12. Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland
13. Smoking, smoking cessation, and lung cancer in the UK since 1950: Combination of national statistics with two case-control studies
14. The genetics of smoking initiation and quantity smoked in Dutch adolescent and young adult twins
15. Colorectal tumours
16. The risk of colorectal cancer in ulcerative colitis: A meta-analysis
17. Relation between colitis and colon cancer
18. Causes
19. Design and analysis issues in case-control studies addressing genetic susceptibility
20. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
21. NAT2 slow acetylation and bladder cancer risk: A meta-analysis of 22 case-control studies conducted in the general population
22. N-Acetyltransferase 2 and bladder cancer: An overview and consideration of the evidence for gene-environment interaction
23. Bias in location and selection of studies
24. A comparison of methods to detect publication bias in meta-analysis
25. International collaborative study on genetic susceptibility to environmental carcinogens
26. The impact of misclassification in case-control studies of gene-environment interactions
27. The problem of multiple inference in studies designed to generate hypotheses
28. Sifting the evidence; what's wrong with significance tests? Another comment on the role of statistical methods
29. Choosing a retrospective design to assess joint genetic and environmental contributions to risk
30. Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: Case-control studies with no controls!
31. Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias
32. Environmental tobacco smoke, genetic susceptibility, and risk of lung cancer in never-smoking women
33. Sample size requirements in case-only designs to detect gene-environment interaction
34. Designing and analysing case-control studies to exploit independence of genotype and exposure
35. Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions
36. Power and sample size calculations in cace-control studies of gene-environmental interaction: Comments on different approaches